JP2016506722A5 - - Google Patents
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- Publication number
- JP2016506722A5 JP2016506722A5 JP2015554120A JP2015554120A JP2016506722A5 JP 2016506722 A5 JP2016506722 A5 JP 2016506722A5 JP 2015554120 A JP2015554120 A JP 2015554120A JP 2015554120 A JP2015554120 A JP 2015554120A JP 2016506722 A5 JP2016506722 A5 JP 2016506722A5
- Authority
- JP
- Japan
- Prior art keywords
- invasive
- deltac
- strong
- cancer
- infectious
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 201000011510 cancer Diseases 0.000 claims 55
- 206010028980 Neoplasm Diseases 0.000 claims 41
- 241000712079 Measles morbillivirus Species 0.000 claims 39
- 208000015181 infectious disease Diseases 0.000 claims 23
- 230000002458 infectious effect Effects 0.000 claims 23
- 210000005134 plasmacytoid dendritic cell Anatomy 0.000 claims 22
- 230000036210 malignancy Effects 0.000 claims 12
- 238000000034 method Methods 0.000 claims 12
- 229960005486 vaccine Drugs 0.000 claims 10
- 230000002238 attenuated effect Effects 0.000 claims 9
- 210000004027 cell Anatomy 0.000 claims 8
- 101710117545 C protein Proteins 0.000 claims 7
- 108090000623 proteins and genes Proteins 0.000 claims 7
- 230000003612 virological effect Effects 0.000 claims 7
- 229960003213 live attenuated measles Drugs 0.000 claims 5
- 208000006178 malignant mesothelioma Diseases 0.000 claims 5
- 239000013592 cell lysate Substances 0.000 claims 4
- 201000001441 melanoma Diseases 0.000 claims 4
- 208000010507 Adenocarcinoma of Lung Diseases 0.000 claims 3
- 239000004480 active ingredient Substances 0.000 claims 3
- 201000005249 lung adenocarcinoma Diseases 0.000 claims 3
- 238000000338 in vitro Methods 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 102000004082 Calreticulin Human genes 0.000 claims 1
- 108090000549 Calreticulin Proteins 0.000 claims 1
- 101100507655 Canis lupus familiaris HSPA1 gene Proteins 0.000 claims 1
- 102000003952 Caspase 3 Human genes 0.000 claims 1
- 108090000397 Caspase 3 Proteins 0.000 claims 1
- 201000005505 Measles Diseases 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 208000009956 adenocarcinoma Diseases 0.000 claims 1
- 230000016571 aggressive behavior Effects 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 230000001640 apoptogenic effect Effects 0.000 claims 1
- 210000000170 cell membrane Anatomy 0.000 claims 1
- 208000035250 cutaneous malignant susceptibility to 1 melanoma Diseases 0.000 claims 1
- 229940127089 cytotoxic agent Drugs 0.000 claims 1
- 230000002068 genetic effect Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 230000009545 invasion Effects 0.000 claims 1
- 230000003211 malignant effect Effects 0.000 claims 1
- 201000005282 malignant pleural mesothelioma Diseases 0.000 claims 1
- 230000005012 migration Effects 0.000 claims 1
- 238000013508 migration Methods 0.000 claims 1
- 238000011275 oncology therapy Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13305086.4A EP2759301A1 (en) | 2013-01-24 | 2013-01-24 | Use of a genetically modified infectious measles virus with enhanced pro-apoptotic properties (MV-DeltaC virus) |
| EP13305086.4 | 2013-01-24 | ||
| PCT/EP2014/051063 WO2014114605A1 (en) | 2013-01-24 | 2014-01-20 | Use of a genetically modified infectious measles virus with enhanced pro-apoptotic properties (mv-deltac virus) in cancer therapy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016506722A JP2016506722A (ja) | 2016-03-07 |
| JP2016506722A5 true JP2016506722A5 (enExample) | 2016-10-20 |
| JP6382223B2 JP6382223B2 (ja) | 2018-08-29 |
Family
ID=47683672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015554120A Active JP6382223B2 (ja) | 2013-01-24 | 2014-01-20 | 癌治療における、遺伝的に改変された、増強されたアポトーシス促進性を有する感染性麻疹ウイルス（ｍｖ−ｄｅｌｔａｃウイルス）の使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US9889193B2 (enExample) |
| EP (2) | EP2759301A1 (enExample) |
| JP (1) | JP6382223B2 (enExample) |
| CN (1) | CN107223055A (enExample) |
| BR (1) | BR112015017692B1 (enExample) |
| CA (1) | CA2898370C (enExample) |
| DK (1) | DK2948157T3 (enExample) |
| ES (1) | ES2700749T3 (enExample) |
| PL (1) | PL2948157T3 (enExample) |
| RU (1) | RU2700083C2 (enExample) |
| WO (1) | WO2014114605A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2759301A1 (en) * | 2013-01-24 | 2014-07-30 | Institut Pasteur | Use of a genetically modified infectious measles virus with enhanced pro-apoptotic properties (MV-DeltaC virus) |
| CN107085095A (zh) * | 2017-03-02 | 2017-08-22 | 江苏华冠生物技术股份有限公司 | 用作酶联试剂盒包被抗原的麻疹病毒裂解液的制备方法 |
| CA3082961A1 (en) * | 2017-12-01 | 2019-06-06 | Gerd Sutter | Immuno-modulated replication-efficient vaccinia virus strain |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7118740B1 (en) | 2000-09-22 | 2006-10-10 | Mayo Foundation For Medical Education And Research | Method for limiting the growth of cancer cells using an attenuated measles virus |
| PT1375512E (pt) | 2002-06-20 | 2009-09-23 | Pasteur Institut | Adnc infeccioso de uma estirpe de vacina aprovada do vírus do sarampo. utilização de composições imunogénicas |
| CA2432738A1 (en) | 2003-02-26 | 2004-08-26 | Philippe Despres | New dengue and west nile viruses proteins and genes coding the foregoing, and their use in vaccinal, therapeutic and diagnostic applications |
| CA2508266A1 (fr) | 2005-06-20 | 2006-12-20 | Institut Pasteur | Polypeptides chimeriques et leurs applications therapeutiques contre une infection a flaviviridae |
| ES2423518T3 (es) | 2006-12-22 | 2013-09-20 | Institut Pasteur | Células y metodología para generar virus de ARN de cadena de sentido negativo no segmentada |
| EP2058003A1 (en) | 2007-10-10 | 2009-05-13 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Medicaments and methods for treating mesothelioma |
| EP2420242A1 (en) * | 2010-08-20 | 2012-02-22 | Lauer, Ulrich M. | Oncolytic measles virus |
| US9399062B2 (en) * | 2011-01-18 | 2016-07-26 | Christopher D. Richardson | PVRL4 (Nectin4) is a receptor for measles virus |
| EP2759301A1 (en) * | 2013-01-24 | 2014-07-30 | Institut Pasteur | Use of a genetically modified infectious measles virus with enhanced pro-apoptotic properties (MV-DeltaC virus) |
-
2013
- 2013-01-24 EP EP13305086.4A patent/EP2759301A1/en not_active Withdrawn
-
2014
- 2014-01-20 ES ES14701698T patent/ES2700749T3/es active Active
- 2014-01-20 BR BR112015017692-5A patent/BR112015017692B1/pt not_active IP Right Cessation
- 2014-01-20 PL PL14701698T patent/PL2948157T3/pl unknown
- 2014-01-20 EP EP14701698.4A patent/EP2948157B1/en active Active
- 2014-01-20 CA CA2898370A patent/CA2898370C/en active Active
- 2014-01-20 US US14/762,559 patent/US9889193B2/en active Active
- 2014-01-20 WO PCT/EP2014/051063 patent/WO2014114605A1/en not_active Ceased
- 2014-01-20 DK DK14701698.4T patent/DK2948157T3/en active
- 2014-01-20 CN CN201480017539.6A patent/CN107223055A/zh active Pending
- 2014-01-20 JP JP2015554120A patent/JP6382223B2/ja active Active
- 2014-01-20 RU RU2015128913A patent/RU2700083C2/ru active
-
2018
- 2018-01-25 US US15/880,133 patent/US10314905B2/en active Active
-
2019
- 2019-06-03 US US16/429,571 patent/US10980873B2/en active Active
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