JP2016500662A - 乳汁から成長因子を精製するための改良されたプロセスおよびその製品 - Google Patents

乳汁から成長因子を精製するための改良されたプロセスおよびその製品 Download PDF

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JP2016500662A
JP2016500662A JP2015534885A JP2015534885A JP2016500662A JP 2016500662 A JP2016500662 A JP 2016500662A JP 2015534885 A JP2015534885 A JP 2015534885A JP 2015534885 A JP2015534885 A JP 2015534885A JP 2016500662 A JP2016500662 A JP 2016500662A
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lactoferrin
milk
rnase
growth factor
permeate
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JP2016500662A5 (https=
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アンドリュー・ブラウン
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マレー・ゴールバーン・コー−オペラティヴ・カンパニー・リミテッド
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Priority claimed from AU2012904391A external-priority patent/AU2012904391A0/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Analytical Chemistry (AREA)
  • Water Supply & Treatment (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
JP2015534885A 2012-10-08 2013-10-08 乳汁から成長因子を精製するための改良されたプロセスおよびその製品 Pending JP2016500662A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2012904391A AU2012904391A0 (en) 2012-10-08 Improved process for purifying milk proteins and products thereof
AU2012904391 2012-10-08
AU2013204850 2013-04-12
AU2013204850A AU2013204850B2 (en) 2012-10-08 2013-04-12 Improved process for purifying milk proteins and products thereof
PCT/AU2013/001154 WO2014056026A1 (en) 2012-10-08 2013-10-08 Improved process for purifying growth factors from milk and products thereof

Publications (2)

Publication Number Publication Date
JP2016500662A true JP2016500662A (ja) 2016-01-14
JP2016500662A5 JP2016500662A5 (https=) 2016-11-24

Family

ID=50476774

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015534885A Pending JP2016500662A (ja) 2012-10-08 2013-10-08 乳汁から成長因子を精製するための改良されたプロセスおよびその製品

Country Status (12)

Country Link
US (1) US20150232823A1 (https=)
EP (1) EP2904007A4 (https=)
JP (1) JP2016500662A (https=)
KR (1) KR20150079618A (https=)
CN (1) CN104736560A (https=)
AU (1) AU2013204850B2 (https=)
BR (1) BR112015007675A2 (https=)
CA (1) CA2887003A1 (https=)
IN (1) IN2015DN02968A (https=)
NZ (1) NZ631827A (https=)
RU (1) RU2015116931A (https=)
WO (1) WO2014056026A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3636657A1 (en) 2018-10-08 2020-04-15 Ablynx N.V. Chromatography-free antibody purification method

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05202098A (ja) * 1992-01-29 1993-08-10 Snow Brand Milk Prod Co Ltd 乳質原料から生理活性物質の製造法
JPH09512536A (ja) * 1994-04-28 1997-12-16 グロペップ プロプライエタリー リミテッド 修飾乳成長因子
JPH1121299A (ja) * 1997-03-27 1999-01-26 Campina Melkunie Bv 牛乳あるいは牛乳誘導物から細胞増殖因子あるいは１種または２種以上の細胞増殖因子を含む組成物を回収する方法
WO2011113100A1 (en) * 2010-03-17 2011-09-22 Murray Goulburn Co-Operative Co. Limited Method of treating a bone disorder

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2584727B1 (fr) * 1985-07-11 1988-06-17 Roussel Uclaf Procede d'extraction de proteines du lait, produits, application du procede, et compositions pharmaceutiques
US5221734A (en) * 1987-10-01 1993-06-22 Ciba-Geigy Corporation Process for preparing a polypeptide growth factor for milk
GB8729031D0 (en) * 1987-12-11 1988-01-27 Express Foods Group Ltd Isolation of immunoglobulin rich fraction from whey
ATE209862T1 (de) * 1994-02-16 2001-12-15 Pharming Intellectual Pty Bv Isolierung von lactoferrin aus milch
US20040219225A1 (en) * 2001-07-20 2004-11-04 Kivits Marinus Gerardus Cornel Process for obtaining growth factor (tgf-beta and igf-1), lactoperoxidase and immunoglobulins preparations from milk products having low mutual cross-contamination
US6875459B2 (en) * 2001-09-10 2005-04-05 Henry B. Kopf Method and apparatus for separation of milk, colostrum, and whey
CN101027080A (zh) * 2004-03-04 2007-08-29 Gtc生物治疗有限公司 用高效切向流过滤进行蛋白质分级的方法
US20050208638A1 (en) * 2004-03-22 2005-09-22 Chao Wu Process for preparing bioactive protein-enriched whey products
US8252341B2 (en) * 2004-09-14 2012-08-28 Paul Brazeau Isolation of growth and differentiating factors from colostrum
FR2901796A1 (fr) * 2006-05-31 2007-12-07 Lab Francais Du Fractionnement Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait
CN101724013B (zh) * 2008-10-24 2012-05-30 哈尔滨康普乳品有限公司 从牛初乳中工业化分离纯化免疫球蛋白a、免疫球蛋白g和乳铁蛋白的方法
RU2579661C2 (ru) * 2009-01-28 2016-04-10 Жан-Поль ПЕРРОДЭН Способ производства лактоферрина, фракция, содержащая лактоферрин, и ее применения

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05202098A (ja) * 1992-01-29 1993-08-10 Snow Brand Milk Prod Co Ltd 乳質原料から生理活性物質の製造法
JPH09512536A (ja) * 1994-04-28 1997-12-16 グロペップ プロプライエタリー リミテッド 修飾乳成長因子
JPH1121299A (ja) * 1997-03-27 1999-01-26 Campina Melkunie Bv 牛乳あるいは牛乳誘導物から細胞増殖因子あるいは１種または２種以上の細胞増殖因子を含む組成物を回収する方法
WO2011113100A1 (en) * 2010-03-17 2011-09-22 Murray Goulburn Co-Operative Co. Limited Method of treating a bone disorder

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
SIIGUR, E. ET AL.: "Vipera Lebetina Venom Nucleases and Nucleotidases", TOXICON, vol. Vol. 60, Issue 2, JPN6017034122, August 2012 (2012-08-01), pages 200, ISSN: 0003780706 *
WHEELER, T.T. ET AL.: "Host-defence-related proteins in cows’ milk", ANIMAL, vol. 6, JPN6017034123, 11 November 2011 (2011-11-11), pages 415 - 422, ISSN: 0003780707 *
熊谷 秋三 ほか: "認知機能および脳由来神経栄養因子に関する運動疫学", RESEARCH IN EXERCISE EPIDEMIOLOGY, vol. 9, JPN6017034127, 2007, pages 1 - 15, ISSN: 0003780708 *

Also Published As

Publication number Publication date
CN104736560A (zh) 2015-06-24
AU2013204850A1 (en) 2014-04-24
AU2013204850B2 (en) 2015-06-25
CA2887003A1 (en) 2014-04-17
IN2015DN02968A (https=) 2015-09-18
RU2015116931A (ru) 2016-11-27
KR20150079618A (ko) 2015-07-08
BR112015007675A2 (pt) 2017-07-04
NZ631827A (en) 2017-01-27
WO2014056026A1 (en) 2014-04-17
EP2904007A4 (en) 2016-05-18
EP2904007A1 (en) 2015-08-12
US20150232823A1 (en) 2015-08-20

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