JP2016104790A5 - - Google Patents
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- JP2016104790A5 JP2016104790A5 JP2016006778A JP2016006778A JP2016104790A5 JP 2016104790 A5 JP2016104790 A5 JP 2016104790A5 JP 2016006778 A JP2016006778 A JP 2016006778A JP 2016006778 A JP2016006778 A JP 2016006778A JP 2016104790 A5 JP2016104790 A5 JP 2016104790A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- vector
- tissue
- dna encoding
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 102000018803 Calgranulin A Human genes 0.000 claims 6
- 108010052500 Calgranulin A Proteins 0.000 claims 6
- 102000018755 Calgranulin B Human genes 0.000 claims 6
- 108010052495 Calgranulin B Proteins 0.000 claims 6
- 210000004027 cell Anatomy 0.000 claims 4
- 230000008929 regeneration Effects 0.000 claims 2
- 238000011069 regeneration method Methods 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- 210000000941 bile Anatomy 0.000 claims 1
- 210000004204 blood vessel Anatomy 0.000 claims 1
- 210000001185 bone marrow Anatomy 0.000 claims 1
- 210000002798 bone marrow cell Anatomy 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000002496 gastric effect Effects 0.000 claims 1
- 210000004392 genitalia Anatomy 0.000 claims 1
- 210000004185 liver Anatomy 0.000 claims 1
- 210000003205 muscle Anatomy 0.000 claims 1
- 210000004923 pancreatic tissue Anatomy 0.000 claims 1
- 210000005259 peripheral blood Anatomy 0.000 claims 1
- 239000011886 peripheral blood Substances 0.000 claims 1
- 230000003248 secreting effect Effects 0.000 claims 1
- 230000017423 tissue regeneration Effects 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008119324 | 2008-04-30 | ||
| JP2008119324 | 2008-04-30 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014019961A Division JP5960735B2 (ja) | 2008-04-30 | 2014-02-05 | 損傷組織の機能的再生促進医薬 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016104790A JP2016104790A (ja) | 2016-06-09 |
| JP2016104790A5 true JP2016104790A5 (cg-RX-API-DMAC7.html) | 2016-07-21 |
Family
ID=41255155
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010510169A Expired - Fee Related JP5814549B2 (ja) | 2008-04-30 | 2009-04-30 | 損傷組織の機能的再生促進医薬 |
| JP2014019961A Active JP5960735B2 (ja) | 2008-04-30 | 2014-02-05 | 損傷組織の機能的再生促進医薬 |
| JP2016006778A Ceased JP2016104790A (ja) | 2008-04-30 | 2016-01-18 | 損傷組織の機能的再生促進医薬 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010510169A Expired - Fee Related JP5814549B2 (ja) | 2008-04-30 | 2009-04-30 | 損傷組織の機能的再生促進医薬 |
| JP2014019961A Active JP5960735B2 (ja) | 2008-04-30 | 2014-02-05 | 損傷組織の機能的再生促進医薬 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20110097309A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2301560A4 (cg-RX-API-DMAC7.html) |
| JP (3) | JP5814549B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20110027665A (cg-RX-API-DMAC7.html) |
| CN (1) | CN102076351A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2009240885A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0911436A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2722906A1 (cg-RX-API-DMAC7.html) |
| RU (1) | RU2010148785A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2009133940A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102076351A (zh) * | 2008-04-30 | 2011-05-25 | 吉诺米克斯股份有限公司 | 损伤组织的功能性再生促进药物 |
| BRPI0911513A2 (pt) * | 2008-04-30 | 2016-07-12 | Genomix Co Ltd | métodos e agentes para coleta de células tronco da medula óssea funcionais in vivo com alta eficiência |
| CN102076350A (zh) * | 2008-04-30 | 2011-05-25 | 吉诺米克斯股份有限公司 | 将骨髓来源的多能干细胞动员到末梢循环的药物 |
| CN104825491A (zh) * | 2009-10-28 | 2015-08-12 | 吉诺米克斯股份有限公司 | 利用骨髓间充质干细胞和/或多能干细胞的血中动员的组织再生促进剂 |
| JP5852773B2 (ja) * | 2010-06-01 | 2016-02-03 | ピアス株式会社 | 骨髄間葉系幹細胞の誘引剤の製造方法、骨髄間葉系幹細胞の誘引方法、及び、骨髄間葉系幹細胞の誘引剤を製造するための使用 |
| CN107188948B (zh) | 2011-04-26 | 2021-11-30 | 斯特姆里姆有限公司 | 用于诱导组织再生的肽及其应用 |
| RU2649069C2 (ru) | 2012-10-25 | 2018-04-02 | Дженомикс Ко., Лтд. | Новый способ лечения повреждения спинного мозга с применением фрагмента hmgb1 |
| CA2889275C (en) | 2012-10-25 | 2021-06-15 | Katsuto Tamai | Novel method for treating cardiac infarction using hmgb1 fragment |
| CA2998410A1 (en) * | 2015-09-14 | 2017-03-23 | Universite Laval | Anti-s100a8 for treating leukemia |
| MX2019008949A (es) | 2017-01-27 | 2019-10-07 | Stemrim Inc | Agente terapeutico para cardiomiopatia, infarto al miocardio antiguo e insuficiencia cardiaca cronica. |
| CA3059544A1 (en) | 2017-04-25 | 2018-11-01 | Shionogi & Co., Ltd. | Peptide for inducing regeneration of tissue, and use thereof |
| EP3656850A4 (en) * | 2017-07-18 | 2021-03-31 | Shiseido Co., Ltd. | MESENCHYMATIC STEM CELL INDUCTION AGENT |
| US12421498B2 (en) | 2017-12-01 | 2025-09-23 | StemRIM Inc. | Ectodermal mesenchymal stem cells and method for producing same |
| CN111542335A (zh) | 2017-12-01 | 2020-08-14 | 斯特姆里姆有限公司 | 炎症性肠病的治疗药 |
| WO2019156137A1 (ja) | 2018-02-08 | 2019-08-15 | 株式会社ステムリム | 乾癬の治療薬 |
| US12304933B2 (en) | 2018-10-05 | 2025-05-20 | StemRIM Inc. | Disease treatment drug based on mesenchymal-stem-cell mobilization |
| EP3756679A1 (en) * | 2019-06-28 | 2020-12-30 | Université de Genève | Compositions for use in the treatment of insulin deficiency conditions |
| CN111494423B (zh) * | 2020-04-22 | 2022-01-25 | 上海市东方医院（同济大学附属东方医院） | 一种干细胞组合物及其应用和干细胞滴液 |
| CN115058388A (zh) * | 2022-03-14 | 2022-09-16 | 福建医科大学附属协和医院 | 间充质干细胞创面修复优势功能亚群及其鉴定和应用 |
| CN120837666A (zh) * | 2025-09-22 | 2025-10-28 | 中国人民解放军军事科学院军事医学研究院 | 靶向巨噬细胞s100a9蛋白在肝纤维化治疗中的应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5658894A (en) * | 1989-04-23 | 1997-08-19 | The Trustees Of The University Of Pennsylvania | Compositions for inhibiting restenosis |
| JP3018313B2 (ja) * | 1996-02-23 | 2000-03-13 | 雪印乳業株式会社 | 骨形成促進及び骨吸収防止剤 |
| EP1114862A3 (de) * | 1999-11-17 | 2003-08-06 | Switch Biotech Aktiengesellschaft | Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankungen sowie ihre Verwendung zur Identifizierung von pharmakologisch aktiven Substanzen |
| AU2001243288B2 (en) * | 2000-02-24 | 2005-11-24 | Life Technologies Corporation | Simultaneous stimulation and concentration of cells |
| US20040191246A1 (en) * | 2003-02-26 | 2004-09-30 | Connelly Patrick R. | Process for in vivo treatment of specific biological targets in bodily fluid |
| EP1390058A2 (en) * | 2001-04-30 | 2004-02-25 | Switch Biotech Aktiengesellschaft | Mrp8/mrp14 heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds and/or wound-healing disturbances |
| DE10121254A1 (de) * | 2001-04-30 | 2002-11-07 | Switch Biotech Ag | MRP8/MRP14 Heterodimers oder seiner Einzelkomponenten alleine oder in Kombination zur Behandlung und/oder Prävention von Hauterkrankungen, Wunden und/oder Wundheilungsstörungen, die durch eine verringerte Menge an MRP8/MRP14 Heterodimeren gekennzeichnet sind |
| AU2002311903A1 (en) * | 2001-05-09 | 2002-11-18 | University Hospitals Of Cleveland | Evaluation of ultraviolet radiation damage to skin using new genemarkers, methods and compositions related thereto |
| US7220723B2 (en) * | 2001-05-15 | 2007-05-22 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
| ITMI20011986A1 (it) * | 2001-09-25 | 2003-03-25 | San Raffaele Centro Fond | Metodo e composizione per l'attivazione di cellule presentanti l'antigene |
| JPWO2003043651A1 (ja) * | 2001-11-19 | 2005-03-10 | 協和醗酵工業株式会社 | 多分化能幹細胞を組織から末梢血へ動員する薬剤 |
| EP1519957B1 (en) * | 2002-07-03 | 2009-03-04 | Fondazione Centro San Raffaele Del Monte Tabor | Use of hmgb1 in the treatment of tissue damage and/or to promote tissue repair |
| WO2004004770A1 (en) * | 2002-07-05 | 2004-01-15 | Universite Laval | Chemotactic factor inhibitor for modulating inflammatory reactions |
| GB0226251D0 (en) * | 2002-11-11 | 2002-12-18 | San Raffaele Centro Fond | Acetylated protein |
| AU2004203732A1 (en) * | 2003-01-03 | 2004-07-22 | Alcedo Biotech Gmbh | Uses of HMGB, HMGN, HMGA proteins |
| DE602004017148D1 (de) * | 2003-03-28 | 2008-11-27 | Univ Laval | S100 protein als aktivator neutrophiler zellen zur verminderung der neutropenie bei der krebsbehandlung |
| WO2006008779A1 (en) * | 2004-07-20 | 2006-01-26 | Provincia Italiana Della Congregazione Dei Figli Dell'immacolata Concezione-Istituto Dermopatico Dell'immacolata | Use of hmgb1 for wound healing |
| KR100593397B1 (ko) * | 2004-10-27 | 2006-06-28 | 한국원자력연구소 | 중배엽 줄기세포 및/또는 ｐ 물질을 함유하는 상처 치유또는 상처 치유 촉진제, 또는 세포 치료제 |
| WO2006047820A1 (en) * | 2004-11-01 | 2006-05-11 | Newsouth Innovations Pty Limited | Use of calgranulin a and b in the promotion and inhibition of mineralized tissue formation |
| HUE035043T2 (en) * | 2006-10-30 | 2018-05-02 | Genomix Co Ltd | A pharmaceutical composition for promoting functional regeneration of damaged tissue |
| CN102076350A (zh) * | 2008-04-30 | 2011-05-25 | 吉诺米克斯股份有限公司 | 将骨髓来源的多能干细胞动员到末梢循环的药物 |
| BRPI0911513A2 (pt) * | 2008-04-30 | 2016-07-12 | Genomix Co Ltd | métodos e agentes para coleta de células tronco da medula óssea funcionais in vivo com alta eficiência |
| CN102076351A (zh) * | 2008-04-30 | 2011-05-25 | 吉诺米克斯股份有限公司 | 损伤组织的功能性再生促进药物 |
-
2009
- 2009-04-30 CN CN2009801252435A patent/CN102076351A/zh active Pending
- 2009-04-30 AU AU2009240885A patent/AU2009240885A1/en not_active Abandoned
- 2009-04-30 KR KR1020107026780A patent/KR20110027665A/ko not_active Withdrawn
- 2009-04-30 JP JP2010510169A patent/JP5814549B2/ja not_active Expired - Fee Related
- 2009-04-30 BR BRPI0911436A patent/BRPI0911436A2/pt not_active Application Discontinuation
- 2009-04-30 WO PCT/JP2009/058519 patent/WO2009133940A1/ja not_active Ceased
- 2009-04-30 RU RU2010148785/10A patent/RU2010148785A/ru not_active Application Discontinuation
- 2009-04-30 EP EP09738877A patent/EP2301560A4/en not_active Withdrawn
- 2009-04-30 CA CA2722906A patent/CA2722906A1/en not_active Abandoned
- 2009-04-30 US US12/990,060 patent/US20110097309A1/en not_active Abandoned
-
2014
- 2014-02-05 JP JP2014019961A patent/JP5960735B2/ja active Active
-
2016
- 2016-01-18 JP JP2016006778A patent/JP2016104790A/ja not_active Ceased
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