JP2016104790A5 - - Google Patents
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- JP2016104790A5 JP2016104790A5 JP2016006778A JP2016006778A JP2016104790A5 JP 2016104790 A5 JP2016104790 A5 JP 2016104790A5 JP 2016006778 A JP2016006778 A JP 2016006778A JP 2016006778 A JP2016006778 A JP 2016006778A JP 2016104790 A5 JP2016104790 A5 JP 2016104790A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- vector
- tissue
- dna encoding
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 102000018803 Calgranulin A Human genes 0.000 claims 6
- 108010052500 Calgranulin A Proteins 0.000 claims 6
- 102000018755 Calgranulin B Human genes 0.000 claims 6
- 108010052495 Calgranulin B Proteins 0.000 claims 6
- 210000004027 cell Anatomy 0.000 claims 4
- 230000008929 regeneration Effects 0.000 claims 2
- 238000011069 regeneration method Methods 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- 210000000941 bile Anatomy 0.000 claims 1
- 210000004204 blood vessel Anatomy 0.000 claims 1
- 210000001185 bone marrow Anatomy 0.000 claims 1
- 210000002798 bone marrow cell Anatomy 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000002496 gastric effect Effects 0.000 claims 1
- 210000004392 genitalia Anatomy 0.000 claims 1
- 210000004185 liver Anatomy 0.000 claims 1
- 210000003205 muscle Anatomy 0.000 claims 1
- 210000004923 pancreatic tissue Anatomy 0.000 claims 1
- 210000005259 peripheral blood Anatomy 0.000 claims 1
- 239000011886 peripheral blood Substances 0.000 claims 1
- 230000003248 secreting effect Effects 0.000 claims 1
- 230000017423 tissue regeneration Effects 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Claims (2)
- 以下の（ａ）から（ｆ）のいずれかに記載の成分を含有する、骨髄細胞を骨髄から末梢血に動員するために用いる薬剤であって、血管または筋肉に投与される薬剤；
（ａ）S100A8タンパク
（ｂ）S100A8タンパク質を分泌する細胞
（ｃ）S100A8タンパク質をコードするDNAが挿入されたベクター
（ｄ）S100A9タンパク質
（ｅ）S100A9タンパク質を分泌する細胞
（ｆ）S100A9タンパク質をコードするDNAが挿入されたベクター。 - 以下の（ａ）から（ｆ）のいずれかに記載の成分を含有する、組織再生促進剤であって、ここで再生が促進される組織が、消化管組織、肝・胆・膵組織、泌尿・生殖器から選択される、組織再生促進剤；
（ａ）S100A8タンパク質
（ｂ）S100A8タンパク質を分泌する細胞
（ｃ）S100A8タンパク質をコードするDNAが挿入されたベクター
（ｄ）S100A9タンパク質
（ｅ）S100A9タンパク質を分泌する細胞
（ｆ）S100A9タンパク質をコードするDNAが挿入されたベクター。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008119324 | 2008-04-30 | ||
| JP2008119324 | 2008-04-30 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014019961A Division JP5960735B2 (ja) | 2008-04-30 | 2014-02-05 | 損傷組織の機能的再生促進医薬 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016104790A JP2016104790A (ja) | 2016-06-09 |
| JP2016104790A5 true JP2016104790A5 (ja) | 2016-07-21 |
Family
ID=41255155
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010510169A Expired - Fee Related JP5814549B2 (ja) | 2008-04-30 | 2009-04-30 | 損傷組織の機能的再生促進医薬 |
| JP2014019961A Active JP5960735B2 (ja) | 2008-04-30 | 2014-02-05 | 損傷組織の機能的再生促進医薬 |
| JP2016006778A Ceased JP2016104790A (ja) | 2008-04-30 | 2016-01-18 | 損傷組織の機能的再生促進医薬 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010510169A Expired - Fee Related JP5814549B2 (ja) | 2008-04-30 | 2009-04-30 | 損傷組織の機能的再生促進医薬 |
| JP2014019961A Active JP5960735B2 (ja) | 2008-04-30 | 2014-02-05 | 損傷組織の機能的再生促進医薬 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20110097309A1 (ja) |
| EP (1) | EP2301560A4 (ja) |
| JP (3) | JP5814549B2 (ja) |
| KR (1) | KR20110027665A (ja) |
| CN (1) | CN102076351A (ja) |
| AU (1) | AU2009240885A1 (ja) |
| BR (1) | BRPI0911436A2 (ja) |
| CA (1) | CA2722906A1 (ja) |
| RU (1) | RU2010148785A (ja) |
| WO (1) | WO2009133940A1 (ja) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8673580B2 (en) * | 2008-04-30 | 2014-03-18 | Genomix Co., Ltd. | Agent for recruitment of bone-marrow-derived pluripotent stem cell into peripheral circulation |
| US9919010B2 (en) | 2008-04-30 | 2018-03-20 | Genomix Co., Ltd. | Method for collecting functional cells in vivo with high efficiency |
| RU2010148785A (ru) * | 2008-04-30 | 2012-06-10 | Дженомикс Ко., Лтд. (Jp) | Фармацевтическое средство для стимуляции функциональной регенерации поврежденной ткани |
| CN102711777B (zh) | 2009-10-28 | 2015-04-15 | 吉诺米克斯股份有限公司 | 利用骨髓间充质干细胞和/或多能干细胞的血中动员的组织再生促进剂 |
| JP5852773B2 (ja) * | 2010-06-01 | 2016-02-03 | ピアス株式会社 | 骨髄間葉系幹細胞の誘引剤の製造方法、骨髄間葉系幹細胞の誘引方法、及び、骨髄間葉系幹細胞の誘引剤を製造するための使用 |
| PT3358011T (pt) | 2011-04-26 | 2020-04-23 | Univ Osaka | Péptido para induzir a regeneração de um tecido e a sua utilização |
| SG11201503236RA (en) | 2012-10-25 | 2015-06-29 | Genomix Co Ltd | Novel method for treating cardiac infarction using hmgb1 fragment |
| ES2673861T3 (es) | 2012-10-25 | 2018-06-26 | Genomix Co., Ltd. | Método novedoso para tratar el daño a la médula espinal utilizando el fragmento de hmgb1 |
| CN108367068B (zh) * | 2015-09-14 | 2021-08-03 | 拉瓦尔大学 | 用于治疗白血病的抗-s100a8 |
| BR112019014921A2 (pt) | 2017-01-27 | 2020-03-31 | StemRIM Inc. | Agente terapêutico para miocardiopatia, infarto antigo do miocárdio e insuficiência cardíaca crônica |
| JP7113007B2 (ja) | 2017-04-25 | 2022-08-04 | 塩野義製薬株式会社 | 組織再生を誘導するためのペプチドとその利用 |
| CN110709506A (zh) * | 2017-07-18 | 2020-01-17 | 株式会社资生堂 | 间充质干细胞导引剂 |
| US20200291359A1 (en) | 2017-12-01 | 2020-09-17 | StemRIM Inc. | Ectodermal mesenchymal stem cells and method for producing same |
| US11298403B2 (en) | 2017-12-01 | 2022-04-12 | StemRIM Inc. | Therapeutic agent for inflammatory bowel disease |
| US20210347839A1 (en) * | 2018-10-05 | 2021-11-11 | StemRIM Inc. | Disease Treatment Drug Based on Mesenchymal-Stem-Cell Mobilization |
| CN111494423B (zh) * | 2020-04-22 | 2022-01-25 | 上海市东方医院（同济大学附属东方医院） | 一种干细胞组合物及其应用和干细胞滴液 |
| CN115058388A (zh) * | 2022-03-14 | 2022-09-16 | 福建医科大学附属协和医院 | 间充质干细胞创面修复优势功能亚群及其鉴定和应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5658894A (en) * | 1989-04-23 | 1997-08-19 | The Trustees Of The University Of Pennsylvania | Compositions for inhibiting restenosis |
| JP3018313B2 (ja) * | 1996-02-23 | 2000-03-13 | 雪印乳業株式会社 | 骨形成促進及び骨吸収防止剤 |
| EP1114862A3 (de) * | 1999-11-17 | 2003-08-06 | Switch Biotech Aktiengesellschaft | Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankungen sowie ihre Verwendung zur Identifizierung von pharmakologisch aktiven Substanzen |
| DK1257632T3 (da) * | 2000-02-24 | 2008-01-28 | Xcyte Therapies Inc | Samtidig stimulering og opkoncentrering af celler |
| US20040191246A1 (en) * | 2003-02-26 | 2004-09-30 | Connelly Patrick R. | Process for in vivo treatment of specific biological targets in bodily fluid |
| AU2002304710A1 (en) * | 2001-04-30 | 2002-11-11 | Switch Biotech Ag | Mrp8/mrp14 heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds and/or wound-healing disturbances |
| DE10121254A1 (de) * | 2001-04-30 | 2002-11-07 | Switch Biotech Ag | MRP8/MRP14 Heterodimers oder seiner Einzelkomponenten alleine oder in Kombination zur Behandlung und/oder Prävention von Hauterkrankungen, Wunden und/oder Wundheilungsstörungen, die durch eine verringerte Menge an MRP8/MRP14 Heterodimeren gekennzeichnet sind |
| AU2002311903A1 (en) * | 2001-05-09 | 2002-11-18 | University Hospitals Of Cleveland | Evaluation of ultraviolet radiation damage to skin using new genemarkers, methods and compositions related thereto |
| US7220723B2 (en) * | 2001-05-15 | 2007-05-22 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
| ITMI20011986A1 (it) * | 2001-09-25 | 2003-03-25 | San Raffaele Centro Fond | Metodo e composizione per l'attivazione di cellule presentanti l'antigene |
| EP1459759A4 (en) * | 2001-11-19 | 2007-08-29 | Kyowa Hakko Kogyo Kk | MEDICAMENT FOR THE MOBILIZATION OF PLURIPOTENTIAL STEM CELLS FROM TISSUE IN THE PERIPHERAL BLOOD |
| CN1671742A (zh) * | 2002-07-03 | 2005-09-21 | 塔博尔山圣拉弗尔基金中心 | Hmgb1在治疗组织损伤和/或促进组织修复中的用途 |
| DE60327075D1 (de) * | 2002-07-05 | 2009-05-20 | Univ Laval | Der entzündungsreaktionen |
| GB0226251D0 (en) * | 2002-11-11 | 2002-12-18 | San Raffaele Centro Fond | Acetylated protein |
| US20070154529A1 (en) * | 2003-01-03 | 2007-07-05 | Alcedo Biotech Gmbh | Uses of dna binding proteins |
| WO2004084928A1 (en) * | 2003-03-28 | 2004-10-07 | UNIVERSITé LAVAL | S100 protein as neutrophil activator for alleviating neutropenia in cancer treatment |
| EP1768693A1 (en) * | 2004-07-20 | 2007-04-04 | Provincia Italiana Della Congregazione Dei Figli Dell'Immacolata Concezione - Istituto Dermopatico Dell'Immacolata | Use of hmgb1 for wound healing |
| KR100593397B1 (ko) * | 2004-10-27 | 2006-06-28 | 한국원자력연구소 | 중배엽 줄기세포 및/또는 ｐ 물질을 함유하는 상처 치유또는 상처 치유 촉진제, 또는 세포 치료제 |
| WO2006047820A1 (en) * | 2004-11-01 | 2006-05-11 | Newsouth Innovations Pty Limited | Use of calgranulin a and b in the promotion and inhibition of mineralized tissue formation |
| DK2055308T3 (en) * | 2006-10-30 | 2017-07-17 | Genomix Co Ltd | PHARMACEUTICALS FOR PROMOTING FUNCTIONAL REGENERATION OF DAMAGED TISSUE |
| US8673580B2 (en) * | 2008-04-30 | 2014-03-18 | Genomix Co., Ltd. | Agent for recruitment of bone-marrow-derived pluripotent stem cell into peripheral circulation |
| US9919010B2 (en) * | 2008-04-30 | 2018-03-20 | Genomix Co., Ltd. | Method for collecting functional cells in vivo with high efficiency |
| RU2010148785A (ru) * | 2008-04-30 | 2012-06-10 | Дженомикс Ко., Лтд. (Jp) | Фармацевтическое средство для стимуляции функциональной регенерации поврежденной ткани |
-
2009
- 2009-04-30 RU RU2010148785/10A patent/RU2010148785A/ru not_active Application Discontinuation
- 2009-04-30 EP EP09738877A patent/EP2301560A4/en not_active Withdrawn
- 2009-04-30 BR BRPI0911436A patent/BRPI0911436A2/pt not_active Application Discontinuation
- 2009-04-30 AU AU2009240885A patent/AU2009240885A1/en not_active Abandoned
- 2009-04-30 CN CN2009801252435A patent/CN102076351A/zh active Pending
- 2009-04-30 WO PCT/JP2009/058519 patent/WO2009133940A1/ja active Application Filing
- 2009-04-30 CA CA2722906A patent/CA2722906A1/en not_active Abandoned
- 2009-04-30 KR KR1020107026780A patent/KR20110027665A/ko not_active Application Discontinuation
- 2009-04-30 US US12/990,060 patent/US20110097309A1/en not_active Abandoned
- 2009-04-30 JP JP2010510169A patent/JP5814549B2/ja not_active Expired - Fee Related
-
2014
- 2014-02-05 JP JP2014019961A patent/JP5960735B2/ja active Active
-
2016
- 2016-01-18 JP JP2016006778A patent/JP2016104790A/ja not_active Ceased
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