JP2016023188A5 - - Google Patents
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- JP2016023188A5 JP2016023188A5 JP2015142061A JP2015142061A JP2016023188A5 JP 2016023188 A5 JP2016023188 A5 JP 2016023188A5 JP 2015142061 A JP2015142061 A JP 2015142061A JP 2015142061 A JP2015142061 A JP 2015142061A JP 2016023188 A5 JP2016023188 A5 JP 2016023188A5
- Authority
- JP
- Japan
- Prior art keywords
- nanoparticles
- particles
- composition
- metal
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 21
- 239000002245 particle Substances 0.000 claims 18
- 239000002105 nanoparticle Substances 0.000 claims 16
- 239000002082 metal nanoparticle Substances 0.000 claims 13
- 239000002923 metal particle Substances 0.000 claims 9
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims 8
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 claims 8
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims 8
- 239000010931 gold Substances 0.000 claims 8
- 229910052737 gold Inorganic materials 0.000 claims 8
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 8
- 208000011580 syndromic disease Diseases 0.000 claims 7
- 208000033808 peripheral neuropathy Diseases 0.000 claims 6
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims 4
- 229910052782 aluminium Inorganic materials 0.000 claims 4
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims 4
- 239000010941 cobalt Substances 0.000 claims 4
- 229910017052 cobalt Inorganic materials 0.000 claims 4
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 claims 4
- 229910052802 copper Inorganic materials 0.000 claims 4
- 239000010949 copper Substances 0.000 claims 4
- 201000001119 neuropathy Diseases 0.000 claims 4
- 230000007823 neuropathy Effects 0.000 claims 4
- 229910052759 nickel Inorganic materials 0.000 claims 4
- 229910052763 palladium Inorganic materials 0.000 claims 4
- 229910052697 platinum Inorganic materials 0.000 claims 4
- 206010003694 Atrophy Diseases 0.000 claims 3
- 230000037444 atrophy Effects 0.000 claims 3
- 210000002569 neuron Anatomy 0.000 claims 3
- 206010065040 AIDS dementia complex Diseases 0.000 claims 2
- 206010006542 Bulbar palsy Diseases 0.000 claims 2
- 208000010693 Charcot-Marie-Tooth Disease Diseases 0.000 claims 2
- 201000011240 Frontotemporal dementia Diseases 0.000 claims 2
- 208000032319 Primary lateral sclerosis Diseases 0.000 claims 2
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims 2
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 claims 2
- 206010046298 Upper motor neurone lesion Diseases 0.000 claims 2
- 208000027418 Wounds and injury Diseases 0.000 claims 2
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 claims 2
- 230000006378 damage Effects 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000007918 intramuscular administration Methods 0.000 claims 2
- 238000007912 intraperitoneal administration Methods 0.000 claims 2
- 238000001990 intravenous administration Methods 0.000 claims 2
- 201000010901 lateral sclerosis Diseases 0.000 claims 2
- 208000005264 motor neuron disease Diseases 0.000 claims 2
- 210000005036 nerve Anatomy 0.000 claims 2
- 210000002241 neurite Anatomy 0.000 claims 2
- 201000002241 progressive bulbar palsy Diseases 0.000 claims 2
- 230000000750 progressive effect Effects 0.000 claims 2
- 229910052709 silver Inorganic materials 0.000 claims 2
- 239000004332 silver Substances 0.000 claims 2
- 238000007920 subcutaneous administration Methods 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 208000030507 AIDS Diseases 0.000 claims 1
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 208000006373 Bell palsy Diseases 0.000 claims 1
- 241000283690 Bos taurus Species 0.000 claims 1
- 208000014644 Brain disease Diseases 0.000 claims 1
- 206010008111 Cerebral haemorrhage Diseases 0.000 claims 1
- 208000009802 Colorado tick fever Diseases 0.000 claims 1
- 208000011990 Corticobasal Degeneration Diseases 0.000 claims 1
- 208000020406 Creutzfeldt Jacob disease Diseases 0.000 claims 1
- 208000003407 Creutzfeldt-Jakob Syndrome Diseases 0.000 claims 1
- 208000010859 Creutzfeldt-Jakob disease Diseases 0.000 claims 1
- 206010012289 Dementia Diseases 0.000 claims 1
- 206010067889 Dementia with Lewy bodies Diseases 0.000 claims 1
- 208000016192 Demyelinating disease Diseases 0.000 claims 1
- 208000032274 Encephalopathy Diseases 0.000 claims 1
- 208000001034 Frostbite Diseases 0.000 claims 1
- 208000021965 Glossopharyngeal Nerve disease Diseases 0.000 claims 1
- 208000035895 Guillain-Barré syndrome Diseases 0.000 claims 1
- 208000031886 HIV Infections Diseases 0.000 claims 1
- 208000037357 HIV infectious disease Diseases 0.000 claims 1
- 206010018985 Haemorrhage intracranial Diseases 0.000 claims 1
- 208000023105 Huntington disease Diseases 0.000 claims 1
- 208000003618 Intervertebral Disc Displacement Diseases 0.000 claims 1
- 206010050296 Intervertebral disc protrusion Diseases 0.000 claims 1
- 208000008574 Intracranial Hemorrhages Diseases 0.000 claims 1
- 206010024229 Leprosy Diseases 0.000 claims 1
- 201000002832 Lewy body dementia Diseases 0.000 claims 1
- 208000016604 Lyme disease Diseases 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 206010049567 Miller Fisher syndrome Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 208000028389 Nerve injury Diseases 0.000 claims 1
- 208000001738 Nervous System Trauma Diseases 0.000 claims 1
- 206010034620 Peripheral sensory neuropathy Diseases 0.000 claims 1
- 208000000609 Pick Disease of the Brain Diseases 0.000 claims 1
- 208000024571 Pick disease Diseases 0.000 claims 1
- 206010035226 Plasma cell myeloma Diseases 0.000 claims 1
- 241000097929 Porphyria Species 0.000 claims 1
- 208000010642 Porphyrias Diseases 0.000 claims 1
- 208000024777 Prion disease Diseases 0.000 claims 1
- 208000012287 Prolapse Diseases 0.000 claims 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 claims 1
- 206010041591 Spinal osteoarthritis Diseases 0.000 claims 1
- 208000036826 VIIth nerve paralysis Diseases 0.000 claims 1
- 208000018756 Variant Creutzfeldt-Jakob disease Diseases 0.000 claims 1
- 206010052428 Wound Diseases 0.000 claims 1
- 210000003050 axon Anatomy 0.000 claims 1
- 230000008499 blood brain barrier function Effects 0.000 claims 1
- 210000001218 blood-brain barrier Anatomy 0.000 claims 1
- 208000005881 bovine spongiform encephalopathy Diseases 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 208000036319 cervical spondylosis Diseases 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 208000010877 cognitive disease Diseases 0.000 claims 1
- 230000007547 defect Effects 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 206010013023 diphtheria Diseases 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 206010015037 epilepsy Diseases 0.000 claims 1
- 201000005442 glossopharyngeal neuralgia Diseases 0.000 claims 1
- 208000006454 hepatitis Diseases 0.000 claims 1
- 231100000283 hepatitis Toxicity 0.000 claims 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 206010022437 insomnia Diseases 0.000 claims 1
- 238000007913 intrathecal administration Methods 0.000 claims 1
- 208000028867 ischemia Diseases 0.000 claims 1
- 231100000518 lethal Toxicity 0.000 claims 1
- 230000001665 lethal effect Effects 0.000 claims 1
- 208000027061 mild cognitive impairment Diseases 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 201000000585 muscular atrophy Diseases 0.000 claims 1
- 201000006938 muscular dystrophy Diseases 0.000 claims 1
- 206010028417 myasthenia gravis Diseases 0.000 claims 1
- 230000008764 nerve damage Effects 0.000 claims 1
- 208000028412 nervous system injury Diseases 0.000 claims 1
- 208000004296 neuralgia Diseases 0.000 claims 1
- 230000014511 neuron projection development Effects 0.000 claims 1
- 210000000578 peripheral nerve Anatomy 0.000 claims 1
- 201000006292 polyarteritis nodosa Diseases 0.000 claims 1
- 208000022256 primary systemic amyloidosis Diseases 0.000 claims 1
- 201000002212 progressive supranuclear palsy Diseases 0.000 claims 1
- 230000002035 prolonged effect Effects 0.000 claims 1
- 201000000196 pseudobulbar palsy Diseases 0.000 claims 1
- 230000008085 renal dysfunction Effects 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 201000000306 sarcoidosis Diseases 0.000 claims 1
- 210000003497 sciatic nerve Anatomy 0.000 claims 1
- 201000005572 sensory peripheral neuropathy Diseases 0.000 claims 1
- 208000002320 spinal muscular atrophy Diseases 0.000 claims 1
- 208000005801 spondylosis Diseases 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- 208000006379 syphilis Diseases 0.000 claims 1
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 1
- 230000008685 targeting Effects 0.000 claims 1
- 210000000115 thoracic cavity Anatomy 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- 206010044652 trigeminal neuralgia Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462025176P | 2014-07-16 | 2014-07-16 | |
| US62/025,176 | 2014-07-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016023188A JP2016023188A (ja) | 2016-02-08 |
| JP2016023188A5 true JP2016023188A5 (https=) | 2018-08-23 |
Family
ID=53758016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015142061A Pending JP2016023188A (ja) | 2014-07-16 | 2015-07-16 | 神経突起伸長の促進におけるナノ金属の使用および神経障害の処置および／または予防 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9655923B2 (https=) |
| EP (1) | EP2974717A3 (https=) |
| JP (1) | JP2016023188A (https=) |
| CN (1) | CN105267235A (https=) |
| TW (1) | TWI643624B (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111848471A (zh) * | 2016-08-05 | 2020-10-30 | 深圳深见医药科技有限公司 | 含金团簇的物质在制备预防和治疗帕金森症药物中的应用 |
| CN111936151A (zh) * | 2017-02-22 | 2020-11-13 | 铠耀纳米银Rx(香港)有限公司 | 利用纳米颗粒银的用于神经保护的组合物和方法 |
| HUE068741T2 (hu) * | 2017-12-19 | 2025-01-28 | Nanobiotix | Nanorészecskék idegi zavarok kezelésére |
| AU2018390163B2 (en) * | 2017-12-19 | 2024-05-02 | Nanobiotix | Nanoparticles for use in enhancing brain performances or in treating stress |
| EP4045063B1 (en) * | 2019-12-27 | 2024-10-02 | Wuhan Vast Conduct Science Foundation Co., Ltd. | Composition and method for treatment of multiple sclerosis |
| CN115317510B (zh) * | 2021-04-25 | 2023-12-01 | 深圳深见医药科技有限公司 | 治疗抑郁症的金团簇、组合物和方法 |
| BR112023022273A2 (pt) * | 2021-04-25 | 2024-01-23 | Shenzhen Profound View Pharmaceutical Tech Co Ltd | Agrupamentos de ouro, composições e métodos para tratamento de depressão |
| CN116870027B (zh) * | 2023-08-07 | 2024-09-20 | 江南大学 | 手性钴纳米粒子在制备治疗阿尔兹海默症药物中的应用 |
| CN117679488B (zh) * | 2023-12-13 | 2024-07-05 | 暨南大学附属第一医院（广州华侨医院） | 纳米拮抗剂Au-ADH1在制备治疗脊髓损伤修复药物的用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20060024343A (ko) * | 2003-02-20 | 2006-03-16 | 가부시키가이샤 시테크 | 귀금속 미립자를 함유하는 의약 |
| TWI414328B (zh) | 2008-09-18 | 2013-11-11 | Nat Health Research Institutes | 可植入性神經再生導管 |
| TWI430858B (zh) * | 2010-07-07 | 2014-03-21 | Leader Machine Co Ltd | Metal particle manufacturing system and method |
-
2015
- 2015-07-16 US US14/800,997 patent/US9655923B2/en not_active Expired - Fee Related
- 2015-07-16 CN CN201510419242.9A patent/CN105267235A/zh active Pending
- 2015-07-16 TW TW104123188A patent/TWI643624B/zh not_active IP Right Cessation
- 2015-07-16 EP EP15177107.8A patent/EP2974717A3/en not_active Withdrawn
- 2015-07-16 JP JP2015142061A patent/JP2016023188A/ja active Pending
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