JP2015534134A - 標識を伴わない高コントラスト細胞撮像のための定量位相顕微鏡検査 - Google Patents
標識を伴わない高コントラスト細胞撮像のための定量位相顕微鏡検査 Download PDFInfo
- Publication number
- JP2015534134A JP2015534134A JP2015539558A JP2015539558A JP2015534134A JP 2015534134 A JP2015534134 A JP 2015534134A JP 2015539558 A JP2015539558 A JP 2015539558A JP 2015539558 A JP2015539558 A JP 2015539558A JP 2015534134 A JP2015534134 A JP 2015534134A
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- JP
- Japan
- Prior art keywords
- light
- phase
- sample
- image
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/06—Means for illuminating specimens
- G02B21/08—Condensers
- G02B21/14—Condensers affording illumination for phase-contrast observation
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0052—Optical details of the image generation
- G02B21/0056—Optical details of the image generation based on optical coherence, e.g. phase-contrast arrangements, interference arrangements
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Microscoopes, Condenser (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/663,069 | 2012-10-29 | ||
US13/663,069 US8934103B2 (en) | 2011-12-22 | 2012-10-29 | Quantitative phase microscopy for label-free high-contrast cell imaging |
PCT/SE2013/051257 WO2014070082A1 (fr) | 2012-10-29 | 2013-10-29 | Microscopie à phase quantitative pour l'imagerie cellulaire à contraste élevé sans marqueur |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2015534134A true JP2015534134A (ja) | 2015-11-26 |
JP2015534134A5 JP2015534134A5 (fr) | 2016-12-15 |
Family
ID=50627810
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015539558A Pending JP2015534134A (ja) | 2012-10-29 | 2013-10-29 | 標識を伴わない高コントラスト細胞撮像のための定量位相顕微鏡検査 |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2912512A4 (fr) |
JP (1) | JP2015534134A (fr) |
WO (1) | WO2014070082A1 (fr) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2018139532A (ja) * | 2017-02-28 | 2018-09-13 | 株式会社島津製作所 | 細胞観察装置 |
JP2019196947A (ja) * | 2018-05-08 | 2019-11-14 | 株式会社ミツトヨ | 光学装置及び形状測定方法 |
JP2020516953A (ja) * | 2017-04-11 | 2020-06-11 | カリコ ライフ サイエンシーズ エルエルシー | 刺激された放出に基づく蛍光顕微鏡法システムおよび方法 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR3050038B1 (fr) * | 2016-04-06 | 2018-05-18 | Lltech Management | Procede et dispositif de microscopie interferentielle plein champ en lumiere incoherente |
CN109375358B (zh) * | 2018-11-28 | 2020-07-24 | 南京理工大学 | 一种基于最优照明模式设计下的差分相衬定量相位显微成像方法 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH1123372A (ja) * | 1997-07-02 | 1999-01-29 | Res Dev Corp Of Japan | 光波コヒーレンス映像方法及びその装置 |
US6806963B1 (en) * | 1999-11-24 | 2004-10-19 | Haag-Streit Ag | Method and device for measuring the optical properties of at least two regions located at a distance from one another in a transparent and/or diffuse object |
JP2005283471A (ja) * | 2004-03-30 | 2005-10-13 | Topcon Corp | 光画像計測装置 |
JP2008534929A (ja) * | 2005-03-25 | 2008-08-28 | マサチユセツツ・インスチチユート・オブ・テクノロジイ | Hilbert位相画像処理のためのシステムと方法 |
US20090134310A1 (en) * | 2007-11-27 | 2009-05-28 | Gregory Douglas Goodno | System and Method for Coherent Beam Combination |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5241364A (en) * | 1990-10-19 | 1993-08-31 | Fuji Photo Film Co., Ltd. | Confocal scanning type of phase contrast microscope and scanning microscope |
US6304330B1 (en) * | 1999-10-06 | 2001-10-16 | Metrolaser, Inc. | Methods and apparatus for splitting, imaging, and measuring wavefronts in interferometry |
EP2420822B1 (fr) * | 2001-06-29 | 2020-09-02 | Universite Libre De Bruxelles | Dispositif destiné à l'obtention par microscopie d'images en trois dimensions d'un échantillon |
WO2006003867A2 (fr) * | 2004-06-30 | 2006-01-12 | Nikon Corporation | Procédé d’observation au microscope, microscope, microscope interférentiel différentiel, microscope de déphasage, microscope interférentiel, procédé de traitement de l’image, et dispositif de traitement de l’image |
TWI326354B (en) * | 2007-05-18 | 2010-06-21 | Univ Nat Taipei Technology | Method and apparatus for simultaneously acquiring interferograms and method for solving the phase |
US8537461B2 (en) * | 2007-11-26 | 2013-09-17 | Carl Zeiss Microimaging Gmbh | Method and configuration for the optical detection of an illuminated specimen |
US8264694B2 (en) * | 2009-03-16 | 2012-09-11 | Ut-Battelle, Llc | Quantitative phase-contrast and excitation-emission systems |
EP2668465A1 (fr) * | 2011-01-25 | 2013-12-04 | Massachusetts Institute Of Technology | Microscopie plein champ à phase de réflexion à prise unique |
US8693000B2 (en) * | 2011-12-22 | 2014-04-08 | General Electric Company | Quantitative phase microscopy for label-free high-contrast cell imaging |
US9097900B2 (en) * | 2012-06-14 | 2015-08-04 | General Electric Company | Quantitative phase microscopy for high-contrast cell imaging using frequency domain phase shift |
-
2013
- 2013-10-29 WO PCT/SE2013/051257 patent/WO2014070082A1/fr active Application Filing
- 2013-10-29 JP JP2015539558A patent/JP2015534134A/ja active Pending
- 2013-10-29 EP EP13851247.0A patent/EP2912512A4/fr not_active Withdrawn
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH1123372A (ja) * | 1997-07-02 | 1999-01-29 | Res Dev Corp Of Japan | 光波コヒーレンス映像方法及びその装置 |
US6806963B1 (en) * | 1999-11-24 | 2004-10-19 | Haag-Streit Ag | Method and device for measuring the optical properties of at least two regions located at a distance from one another in a transparent and/or diffuse object |
JP2005283471A (ja) * | 2004-03-30 | 2005-10-13 | Topcon Corp | 光画像計測装置 |
JP2008534929A (ja) * | 2005-03-25 | 2008-08-28 | マサチユセツツ・インスチチユート・オブ・テクノロジイ | Hilbert位相画像処理のためのシステムと方法 |
US20090134310A1 (en) * | 2007-11-27 | 2009-05-28 | Gregory Douglas Goodno | System and Method for Coherent Beam Combination |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2018139532A (ja) * | 2017-02-28 | 2018-09-13 | 株式会社島津製作所 | 細胞観察装置 |
JP2020516953A (ja) * | 2017-04-11 | 2020-06-11 | カリコ ライフ サイエンシーズ エルエルシー | 刺激された放出に基づく蛍光顕微鏡法システムおよび方法 |
JP7066740B2 (ja) | 2017-04-11 | 2022-05-13 | カリコ ライフ サイエンシーズ エルエルシー | 刺激された放出に基づく蛍光顕微鏡法システムおよび方法 |
JP2019196947A (ja) * | 2018-05-08 | 2019-11-14 | 株式会社ミツトヨ | 光学装置及び形状測定方法 |
JP7080718B2 (ja) | 2018-05-08 | 2022-06-06 | 株式会社ミツトヨ | 光学装置及び形状測定方法 |
Also Published As
Publication number | Publication date |
---|---|
EP2912512A1 (fr) | 2015-09-02 |
EP2912512A4 (fr) | 2016-07-13 |
WO2014070082A1 (fr) | 2014-05-08 |
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