JP2015533791A5 - - Google Patents
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- JP2015533791A5 JP2015533791A5 JP2015530440A JP2015530440A JP2015533791A5 JP 2015533791 A5 JP2015533791 A5 JP 2015533791A5 JP 2015530440 A JP2015530440 A JP 2015530440A JP 2015530440 A JP2015530440 A JP 2015530440A JP 2015533791 A5 JP2015533791 A5 JP 2015533791A5
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- JP
- Japan
- Prior art keywords
- seq
- peptide
- amino acid
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 125000003275 alpha amino acid group Chemical group 0.000 claims 6
- 208000008787 Cardiovascular Disease Diseases 0.000 claims 4
- 150000007523 nucleic acids Chemical group 0.000 claims 3
- 229920001850 Nucleic acid sequence Polymers 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 206010003210 Arteriosclerosis Diseases 0.000 claims 1
- 208000010125 Myocardial Infarction Diseases 0.000 claims 1
- 230000000996 additive Effects 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 201000001320 atherosclerosis Diseases 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12306079 | 2012-09-07 | ||
| EP12306079.0 | 2012-09-07 | ||
| PCT/EP2013/068628 WO2014037565A2 (en) | 2012-09-07 | 2013-09-09 | Inhibiting peptides derived from triggering receptor expressed on myeloid cells-1 (trem-1) trem-like transcript 1 (tlt-1) and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015533791A JP2015533791A (ja) | 2015-11-26 |
| JP2015533791A5 true JP2015533791A5 (US20090208454A1-20090820-C00047.png) | 2016-06-02 |
| JP6307080B2 JP6307080B2 (ja) | 2018-04-04 |
Family
ID=46826397
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015530440A Active JP6307080B2 (ja) | 2012-09-07 | 2013-09-09 | 骨髄細胞に発現する誘発性受容体１（ｔｒｅｍ−１）ｔｒｅｍ様転写産物１（ｔｌｔ−１）に由来する阻害ペプチドおよびその使用 |
Country Status (24)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3307782A4 (en) * | 2015-06-12 | 2018-12-26 | MacKay Medical Foundation the Presbyterian Church in Taiwan MacKay Memorial Hospital | Methods and antibodies for modulation of immunoresponse |
| JP7023853B2 (ja) | 2016-03-04 | 2022-02-22 | アレクトル エルエルシー | 抗ｔｒｅｍ１抗体及びその使用方法 |
| JOP20190248A1 (ar) | 2017-04-21 | 2019-10-20 | Amgen Inc | بروتينات ربط مولد ضد trem2 واستخداماته |
| EP3836951A1 (en) | 2018-08-13 | 2021-06-23 | Signablok, Inc. | Peptides and compositions for targeted treatment and imaging |
| US20230016187A1 (en) * | 2019-11-25 | 2023-01-19 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Trem-1 inhibitors for the treatment of vaso-occlusions and tissue injuries in patients suffering from sickle cell disease |
| CN116490199A (zh) * | 2020-06-05 | 2023-07-25 | 伊诺特伦公司 | 用于治疗患有冠状病毒感染的受试者的trem-1抑制剂 |
| MX2022016548A (es) | 2020-06-26 | 2023-03-14 | Amgen Inc | Muteínas de il-10 y proteínas de fusión de las mismas. |
| WO2022189659A1 (en) | 2021-03-12 | 2022-09-15 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Trem-1 inhibitors for the treatment of marfan syndrome |
| CA3224001A1 (en) | 2021-06-25 | 2022-12-29 | Amgen Inc. | Treatment of cardiovascular disease with trem-1 antigen binding proteins |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4861719A (en) | 1986-04-25 | 1989-08-29 | Fred Hutchinson Cancer Research Center | DNA constructs for retrovirus packaging cell lines |
| US5278056A (en) | 1988-02-05 | 1994-01-11 | The Trustees Of Columbia University In The City Of New York | Retroviral packaging cell lines and process of using same |
| US5670488A (en) | 1992-12-03 | 1997-09-23 | Genzyme Corporation | Adenovirus vector for gene therapy |
| CA2156725A1 (en) | 1993-02-22 | 1994-09-01 | Warren S. Pear | Production of high titer helper-free retroviruses by transient transfection |
| FR2712812B1 (fr) | 1993-11-23 | 1996-02-09 | Centre Nat Rech Scient | Composition pour la production de produits thérapeutiques in vivo. |
| RU2186110C2 (ru) | 1994-09-12 | 2002-07-27 | Шеринг Аг | Рекомбинантный белок asp-паллидипин, способ его производства и очистки, вектор, штамм, фармацевтическая композиция |
| IL116816A (en) | 1995-01-20 | 2003-05-29 | Rhone Poulenc Rorer Sa | Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof |
| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| IL149251A0 (en) * | 2000-08-22 | 2002-11-10 | Brigham & Womens Hospital | Diagnosis and treatment of cardiovascular conditions |
| US20040180409A1 (en) | 2003-03-16 | 2004-09-16 | Mcvicar Daniel | TLT-1, a novel platelet-associated receptor and uses therefor |
| GB0426146D0 (en) * | 2004-11-29 | 2004-12-29 | Bioxell Spa | Therapeutic peptides and method |
| US7553936B2 (en) * | 2006-12-04 | 2009-06-30 | The United States of America as represented by Secretary Department of Health and Human Services | Anti-TREM-like transcript-1 (TLT-1) antibodies and compositions |
| CN101821621A (zh) | 2007-07-23 | 2010-09-01 | 拜奥克塞尔有限公司 | 筛选、治疗和诊断 |
| DE102009018620A1 (de) | 2009-04-27 | 2010-10-28 | Carefusion Germany 234 Gmbh | Ansteuer- und Auswerteschaltung, Messgerät sowie Verfahren zum Messen der Konzentration eines Gases |
| JP5467313B2 (ja) * | 2009-09-28 | 2014-04-09 | 国立大学法人 岡山大学 | アテローム動脈硬化抑制剤 |
| HUE050815T2 (hu) | 2010-04-08 | 2021-01-28 | Inst Nat Sante Rech Med | A trem-szerû 1. transzkriptumból (tlt-1) származó gátló peptidek és azok felhasználása |
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2013
- 2013-09-09 RS RS20200634A patent/RS60421B1/sr unknown
- 2013-09-09 NZ NZ705899A patent/NZ705899A/en unknown
- 2013-09-09 HU HUE13759234A patent/HUE051557T2/hu unknown
- 2013-09-09 SI SI201331729T patent/SI2892920T1/sl unknown
- 2013-09-09 US US14/426,562 patent/US9657081B2/en active Active
- 2013-09-09 EP EP13759234.1A patent/EP2892920B1/en active Active
- 2013-09-09 PT PT137592341T patent/PT2892920T/pt unknown
- 2013-09-09 CN CN201380058170.9A patent/CN104837865B/zh active Active
- 2013-09-09 KR KR1020157008973A patent/KR102181384B1/ko active IP Right Grant
- 2013-09-09 PL PL13759234T patent/PL2892920T3/pl unknown
- 2013-09-09 LT LTEP13759234.1T patent/LT2892920T/lt unknown
- 2013-09-09 ES ES13759234T patent/ES2797625T3/es active Active
- 2013-09-09 CA CA2884121A patent/CA2884121C/en active Active
- 2013-09-09 AU AU2013311606A patent/AU2013311606B2/en active Active
- 2013-09-09 RU RU2015112625A patent/RU2672341C2/ru not_active Application Discontinuation
- 2013-09-09 DK DK13759234.1T patent/DK2892920T3/da active
- 2013-09-09 MX MX2015002994A patent/MX2015002994A/es unknown
- 2013-09-09 JP JP2015530440A patent/JP6307080B2/ja active Active
- 2013-09-09 WO PCT/EP2013/068628 patent/WO2014037565A2/en active Application Filing
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2015
- 2015-03-08 IL IL237615A patent/IL237615B/en active IP Right Grant
- 2015-03-16 ZA ZA2015/01779A patent/ZA201501779B/en unknown
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2016
- 2016-01-08 HK HK16100154.4A patent/HK1212360A1/xx unknown
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2020
- 2020-06-02 HR HRP20200875TT patent/HRP20200875T8/hr unknown
- 2020-06-02 CY CY20201100521T patent/CY1123014T1/el unknown
