JP2015532641A5 - - Google Patents

Download PDF

Info

Publication number
JP2015532641A5
JP2015532641A5 JP2015527444A JP2015527444A JP2015532641A5 JP 2015532641 A5 JP2015532641 A5 JP 2015532641A5 JP 2015527444 A JP2015527444 A JP 2015527444A JP 2015527444 A JP2015527444 A JP 2015527444A JP 2015532641 A5 JP2015532641 A5 JP 2015532641A5
Authority
JP
Japan
Prior art keywords
composition
agent
subject
drug
item
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2015527444A
Other languages
English (en)
Japanese (ja)
Other versions
JP6370785B2 (ja
JP2015532641A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/032200 external-priority patent/WO2014028057A1/en
Publication of JP2015532641A publication Critical patent/JP2015532641A/ja
Publication of JP2015532641A5 publication Critical patent/JP2015532641A5/ja
Application granted granted Critical
Publication of JP6370785B2 publication Critical patent/JP6370785B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2015527444A 2012-08-15 2013-03-15 前立腺がんイメージングのための前立腺特異的抗原薬剤およびその使用方法 Active JP6370785B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261683305P 2012-08-15 2012-08-15
US61/683,305 2012-08-15
PCT/US2013/032200 WO2014028057A1 (en) 2012-08-15 2013-03-15 Prostate specific antigen agents and methods of using same for prostate cancer imaging

Publications (3)

Publication Number Publication Date
JP2015532641A JP2015532641A (ja) 2015-11-12
JP2015532641A5 true JP2015532641A5 (enExample) 2016-05-12
JP6370785B2 JP6370785B2 (ja) 2018-08-08

Family

ID=48170795

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015527444A Active JP6370785B2 (ja) 2012-08-15 2013-03-15 前立腺がんイメージングのための前立腺特異的抗原薬剤およびその使用方法

Country Status (7)

Country Link
US (1) US9371362B2 (enExample)
EP (1) EP2885006B1 (enExample)
JP (1) JP6370785B2 (enExample)
CN (1) CN104955484B (enExample)
AU (1) AU2013303233C1 (enExample)
CA (1) CA2882019C (enExample)
WO (1) WO2014028057A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5106397B2 (ja) 2005-09-02 2012-12-26 ビセン メディカル, インコーポレイテッド 生体適合性n,n−二置換スルホンアミド含有蛍光色素標識
EP1973575B1 (en) 2005-12-22 2019-07-24 Visen Medical, Inc. Biocompatible fluorescent metal oxide nanoparticles
EP2244741B1 (en) 2008-01-18 2015-03-25 VisEn Medical, Inc. Fluorescent imaging agents
EP2707102B1 (en) 2011-05-09 2019-11-13 Visen Medical, Inc. Carbonic anhydrase targeting agents and methods of using same
EP2831264B1 (en) 2012-03-30 2019-07-10 VisEn Medical, Inc. Bacterial imaging agents and methods of using same
WO2014028057A1 (en) 2012-08-15 2014-02-20 Visen Medical, Inc. Prostate specific antigen agents and methods of using same for prostate cancer imaging
CN105073761B (zh) 2013-03-15 2020-10-20 文森医学公司 用于体外和体内成像和检测的取代的硅杂蒽阳离子红至近红外荧光染料
EP2970674B1 (en) 2013-03-15 2018-12-12 VisEn Medical, Inc. 4,4-disubstituted cyclohexyl bridged heptamethine cyanine dyes and uses thereof
US9713649B2 (en) 2014-01-24 2017-07-25 The Cleveland Clinic Foundation PSMA-targeting imaging agents
ES2999358T3 (en) 2015-08-18 2025-02-25 Rakuten Medical Inc Phthalocyanine dye conjugates and their storage
ES2992591T3 (en) 2015-08-18 2024-12-16 Rakuten Medical Inc Compositions, combinations and related methods for photoimmunotherapy
JP2021500373A (ja) * 2017-10-23 2021-01-07 ザ・ジョンズ・ホプキンス・ユニバーシティ 線維芽細胞活性化タンパク質α(FAP−α)を標的とする撮像剤および放射線療法用薬剤
WO2024181455A1 (ja) * 2023-02-27 2024-09-06 富士フイルム株式会社 化合物及びこれを用いた標識生体物質
EP4674860A1 (en) * 2023-02-27 2026-01-07 FUJIFILM Corporation Compound and labeled biomaterial using same
WO2024181456A1 (ja) * 2023-02-27 2024-09-06 富士フイルム株式会社 化合物及びこれを用いた標識生体物質

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4647447A (en) 1981-07-24 1987-03-03 Schering Aktiengesellschaft Diagnostic media
US5627027A (en) 1986-04-18 1997-05-06 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
US5569587A (en) 1986-04-18 1996-10-29 Carnegie Mellon University Method for labeling and detecting materials employing luminescent arysulfonate cyanine dyes
US5268486A (en) 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes
US4981977A (en) 1989-06-09 1991-01-01 Carnegie-Mellon University Intermediate for and fluorescent cyanine dyes containing carboxylic acid groups
JPH08501097A (ja) 1992-09-04 1996-02-06 ザ ゼネラル ホスピタル コーポレーション 臨床診断及び治療用部分を含む生体適合性ポリマー
US5808044A (en) 1993-01-22 1998-09-15 Pharmacia Biotech Inc. Indocarbocyanine and benzindocarbocyanine phosphoramidites
US5866679A (en) 1994-06-28 1999-02-02 Merck & Co., Inc. Peptides
DE4445065A1 (de) 1994-12-07 1996-06-13 Diagnostikforschung Inst Verfahren zur In-vivo-Diagnostik mittels NIR-Strahlung
US6127134A (en) 1995-04-20 2000-10-03 Carnegie Mellon University Difference gel electrophoresis using matched multiple dyes
US6008373A (en) 1995-06-07 1999-12-28 Carnegie Mellon University Fluorescent labeling complexes with large stokes shift formed by coupling together cyanine and other fluorochromes capable of resonance energy transfer
IT1276833B1 (it) 1995-10-09 1997-11-03 Sorin Biomedica Cardio Spa Coloranti fluorescenti della famiglia della solfo benz e indocianina
US6004536A (en) 1995-11-14 1999-12-21 Molecular Probes, Inc. Lipophilic cyanine dyes with enchanced aqueous solubilty
CA2251985A1 (en) 1996-04-19 1997-10-30 Alan Lewis Hamilton Squarate dyes and their use in fluorescent sequencing method
US6177404B1 (en) 1996-10-15 2001-01-23 Merck & Co., Inc. Conjugates useful in the treatment of benign prostatic hyperplasia
DE19717904A1 (de) 1997-04-23 1998-10-29 Diagnostikforschung Inst Säurelabile und enzymatisch spaltbare Farbstoffkonstrukte zur Diagnostik mit Nahinfrarotlicht und zur Therapie
US5877310A (en) 1997-04-25 1999-03-02 Carnegie Mellon University Glycoconjugated fluorescent labeling reagents
US6127333A (en) 1997-07-10 2000-10-03 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6391305B1 (en) 1997-09-10 2002-05-21 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
EP1036093A1 (en) * 1997-12-02 2000-09-20 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
ZA9810974B (en) 1997-12-02 1999-06-03 Merck & Co Inc Conjugates useful in the treatment of prostate cancer
US6133445A (en) 1997-12-17 2000-10-17 Carnegie Mellon University Rigidized trimethine cyanine dyes
AU3386399A (en) 1998-04-08 1999-10-25 Ewald A. Terpetschnig Luminescent compounds
US6002003A (en) 1998-04-14 1999-12-14 Beckman Instruments, Inc. Cyanine dye activating group with improved coupling selectivity
US6592847B1 (en) 1998-05-14 2003-07-15 The General Hospital Corporation Intramolecularly-quenched near infrared flourescent probes
US6083486A (en) 1998-05-14 2000-07-04 The General Hospital Corporation Intramolecularly-quenched near infrared fluorescent probes
US6174858B1 (en) * 1998-11-17 2001-01-16 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
ATE284433T1 (de) 1999-07-02 2004-12-15 Visen Medical Inc Fluorescierende cyaninlabels mit einem sulphamidobrückenglied
DE60020584T2 (de) 1999-09-20 2006-04-27 Fuji Photo Film Co., Ltd., Minami-Ashigara Verbindungen zur fluoreszenz-kennzeichnung
EP1341557A2 (en) 2000-10-27 2003-09-10 Beth Israel Deaconess Medical Center Non-isotopic detection of osteoblastic activity in vivo using modified bisphosphonates
US6615063B1 (en) 2000-11-27 2003-09-02 The General Hospital Corporation Fluorescence-mediated molecular tomography
EP1209205A1 (en) 2000-11-28 2002-05-29 Innosense S.r.l. Improved process and method for the preparation of asymetric monofunctionalised indocyanine labelling reagents and obtained compounds
EP1221465A1 (en) 2001-01-03 2002-07-10 Innosense S.r.l. Symmetric, monofunctionalised polymethine dyes labelling reagents
US20030044353A1 (en) 2001-01-05 2003-03-06 Ralph Weissleder Activatable imaging probes
ATE536993T1 (de) 2002-01-02 2011-12-15 Visen Medical Inc Aminfunktionalisierte superparamagnetisierte nanoteilchen für die synthese von biokonjugaten
WO2003061711A2 (en) 2002-01-16 2003-07-31 Visen Medical, Inc. Chromophore probes for optical imaging
AU2003225763A1 (en) 2002-03-11 2003-09-29 Visen Medical, Inc. Optical imaging probes
EP2410315B1 (en) 2002-06-04 2020-04-01 Visen Medical, Inc. Imaging volumes with arbitrary geometries in contact and non-contact tomography
US20060239916A1 (en) 2005-01-07 2006-10-26 Kai Licha Use of cyanine dyes for the diagnosis of proliferative diseases
TW200624440A (en) * 2005-01-07 2006-07-16 Univ Kaohsiung Medical Prostate-specific antigen (psa) probes for optical imaging
ES2612738T3 (es) * 2005-09-02 2017-05-18 Visen Medical, Inc. Agentes de formación de imágenes fluorescentes biocompatibles
JP5106397B2 (ja) 2005-09-02 2012-12-26 ビセン メディカル, インコーポレイテッド 生体適合性n,n−二置換スルホンアミド含有蛍光色素標識
US8173819B2 (en) 2005-09-02 2012-05-08 Visen Medical, Inc. Nicotinic and picolinic acid derived near-infrared fluorophores
EP1973575B1 (en) 2005-12-22 2019-07-24 Visen Medical, Inc. Biocompatible fluorescent metal oxide nanoparticles
WO2007109364A2 (en) 2006-03-20 2007-09-27 The General Hospital Corporation Intramolecularly quenched fluorochrome conjugates and methods of use
EP2118206B9 (en) 2007-02-09 2018-08-29 Visen Medical, Inc. Polycyclo dyes and use thereof
WO2008109832A2 (en) 2007-03-08 2008-09-12 Visen Medical, Inc. Viable near-infrared fluorochrome labeled cells and methods of making and using same
EP2244741B1 (en) * 2008-01-18 2015-03-25 VisEn Medical, Inc. Fluorescent imaging agents
EP3673922A1 (en) 2008-03-14 2020-07-01 VisEn Medical, Inc. Integrin targeting agents and methods of using same
US8864821B2 (en) 2008-11-26 2014-10-21 Visen Medical, Inc. Methods and compositions for identifying subjects at risk of developing stent thrombosis
EP2571997A2 (en) * 2010-05-21 2013-03-27 Ohmx Corporation Enzymatic activity of psa as diagnostic marker for prostate cancer
EP2707102B1 (en) 2011-05-09 2019-11-13 Visen Medical, Inc. Carbonic anhydrase targeting agents and methods of using same
WO2014028057A1 (en) 2012-08-15 2014-02-20 Visen Medical, Inc. Prostate specific antigen agents and methods of using same for prostate cancer imaging

Similar Documents

Publication Publication Date Title
US20240042063A1 (en) LINKED AND OTHER pH-TRIGGERED COMPOUNDS
AU2022203395B2 (en) Fluorescent compound comprising a fluorophore conjugated to a pH -triggered polypeptide
JP6370785B2 (ja) 前立腺がんイメージングのための前立腺特異的抗原薬剤およびその使用方法
ES2876874T3 (es) Plataforma innovadora de tecnología para la unión específica de células necróticas
ES2488942T3 (es) Sustancias diagnósticas para un análisis por formación de imágenes óptica sobre la base de formulaciones de nanopartículas
CN103687854A (zh) 碳酸酐酶靶向剂及其使用方法
JP2016521254A5 (enExample)
JP5500875B2 (ja) 新規化合物、該新規化合物を用いたプローブ及び該新規化合物もしくは該プローブを用いた蛍光イメージング用造影剤
JP2016519080A5 (enExample)
EP1485716A1 (en) Optical imaging probes
JP2013526547A (ja) 光学造影および療法のタンデムのための官能性架橋型ナノ構造物
CN104245954A (zh) 细菌成像剂及其使用方法
KR101188979B1 (ko) 광역학 진단 또는 치료를 위한 생체 적합성 고분자와 광감작제의 결합체 및 이의 제조방법
US20210121569A1 (en) Nanotherapeutic systems and methods using particle-driven photodynamic therapy (pdt)
US20230416457A1 (en) Dual modality ups nanoprobes for tumor acidosis imaging
US10172964B2 (en) Compound or salt thereof and contrast agent for optical imaging
JP6711601B2 (ja) 光音響イメージング用造影剤
WO2021009219A1 (en) A receptor-targeting conjugate with an effective pharmacokinetic profile
US11986540B2 (en) Compositions including pafolacianine for the identification of malignant lesions
US20240066142A1 (en) A upar (urokinase plasminogen activator receptor)-targeting conjugate