JP2015526391A - 抗ｉ型インターフェロン受容体（ｉｆｎａｒ）抗体のための固定用量レジメン - Google Patents

抗ｉ型インターフェロン受容体（ｉｆｎａｒ）抗体のための固定用量レジメン Download PDF

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JP2015526391A
JP2015526391A JP2015517382A JP2015517382A JP2015526391A JP 2015526391 A JP2015526391 A JP 2015526391A JP 2015517382 A JP2015517382 A JP 2015517382A JP 2015517382 A JP2015517382 A JP 2015517382A JP 2015526391 A JP2015526391 A JP 2015526391A
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patient
antibody
disorder
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JP2015526391A5 (enExample
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ヒッグズ，ブランドン
ヤオ，イホン
ワン，ビン
ロスコス，ローリン
チャン，リンダ
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メディミューン，エルエルシー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C—CHEMISTRY; METALLURGY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
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    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00—Oligonucleotides characterized by their use
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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JP2015517382A 2012-06-13 2013-06-12 抗ｉ型インターフェロン受容体（ｉｆｎａｒ）抗体のための固定用量レジメン Pending JP2015526391A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261659138P 2012-06-13 2012-06-13
US61/659,138 2012-06-13
PCT/US2013/045327 WO2013188494A1 (en) 2012-06-13 2013-06-12 Fixed dosage regimens for anti-type i interferon receptor (ifnar) antibodies

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JP2017231307A Division JP2018065845A (ja) 2012-06-13 2017-12-01 抗ｉ型インターフェロン受容体（ｉｆｎａｒ）抗体のための固定用量レジメン

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JP2015526391A true JP2015526391A (ja) 2015-09-10
JP2015526391A5 JP2015526391A5 (enExample) 2016-07-14

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JP2015517382A Pending JP2015526391A (ja) 2012-06-13 2013-06-12 抗ｉ型インターフェロン受容体（ｉｆｎａｒ）抗体のための固定用量レジメン
JP2017231307A Pending JP2018065845A (ja) 2012-06-13 2017-12-01 抗ｉ型インターフェロン受容体（ｉｆｎａｒ）抗体のための固定用量レジメン
JP2019033979A Active JP6814238B2 (ja) 2012-06-13 2019-02-27 抗ｉ型インターフェロン受容体（ｉｆｎａｒ）抗体のための固定用量レジメン
JP2020174325A Ceased JP2021042208A (ja) 2012-06-13 2020-10-16 抗ｉ型インターフェロン受容体（ｉｆｎａｒ）抗体のための固定用量レジメン
JP2021112707A Active JP7123225B2 (ja) 2012-06-13 2021-07-07 抗ｉ型インターフェロン受容体（ｉｆｎａｒ）抗体のための固定用量レジメン

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JP2019033979A Active JP6814238B2 (ja) 2012-06-13 2019-02-27 抗ｉ型インターフェロン受容体（ｉｆｎａｒ）抗体のための固定用量レジメン
JP2020174325A Ceased JP2021042208A (ja) 2012-06-13 2020-10-16 抗ｉ型インターフェロン受容体（ｉｆｎａｒ）抗体のための固定用量レジメン
JP2021112707A Active JP7123225B2 (ja) 2012-06-13 2021-07-07 抗ｉ型インターフェロン受容体（ｉｆｎａｒ）抗体のための固定用量レジメン

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US (1) US9493570B2 (enExample)
EP (1) EP2861621A4 (enExample)
JP (5) JP2015526391A (enExample)
KR (3) KR102185237B1 (enExample)
CN (3) CN104603152A (enExample)
AU (3) AU2013274389A1 (enExample)
CA (1) CA2876636C (enExample)
HK (1) HK1209758A1 (enExample)
WO (1) WO2013188494A1 (enExample)

Cited By (2)

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Publication number Priority date Publication date Assignee Title
JP2024511227A (ja) * 2021-04-23 2024-03-12 アストラゼネカ・アクチエボラーグ 皮下注射のための抗ｉｆｎａｒ１投薬計画
JP2024518735A (ja) * 2021-04-23 2024-05-02 アストラゼネカ・アクチエボラーグ 抗ｉ型ｉｎｆ受容体抗体アニフロルマブによるループス腎炎の治療

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KR100680048B1 (ko) * 2006-01-23 2007-02-08 쌍용자동차 주식회사 자동차 도장용 크레인의 구조
CN108699608A (zh) * 2015-10-09 2018-10-23 基因前沿公司 用于预测和诊断人巨细胞病毒(hCMV)先天性传播的方法和试剂盒
MA45554A (fr) 2016-07-01 2019-05-08 Resolve Therapeutics Llc Fusions de binucléase optimisées.
CN106243226B (zh) * 2016-08-05 2019-02-12 北京智仁美博生物科技有限公司 抗人ifnar1的抗体及其用途
US20200031943A1 (en) 2017-03-21 2020-01-30 Austrianni Gmbh Type 1 interferon receptor antagonists for use in methods of treating tuberculosis and other infectious diseases
CN111315767B (zh) 2017-08-22 2025-03-18 萨纳生物有限责任公司 可溶性干扰素受体及其用途
US11139051B2 (en) 2018-10-02 2021-10-05 Origent Data Sciences, Inc. Systems and methods for designing clinical trials
CA3117102A1 (en) 2018-10-26 2020-04-30 Janssen Biotech, Inc. Type i interferon signatures and methods of use
JP7386877B2 (ja) 2019-01-31 2023-11-27 イミューンセント バイオテクノロジー，インコーポレイテッド 新規の抗ｉｆｎａｒ１抗体
CN111892653A (zh) * 2019-07-03 2020-11-06 长春恒晓生物科技有限责任公司 制备粘病毒抗性蛋白1抗体及建立检测mx1方法
TW202317617A (zh) * 2021-04-23 2023-05-01 瑞典商阿斯特捷利康公司 皮膚紅斑狼瘡之治療
AU2022317215A1 (en) * 2021-07-27 2024-02-29 Astrazeneca Ab Treatment of lupus
WO2025022280A1 (en) 2023-07-21 2025-01-30 Astrazeneca Ab Treatment of neurodegenerative diseases
GB202402824D0 (en) * 2024-02-28 2024-04-10 Astrazeneca Ab Treatment of chronic kidney disease

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024511227A (ja) * 2021-04-23 2024-03-12 アストラゼネカ・アクチエボラーグ 皮下注射のための抗ｉｆｎａｒ１投薬計画
JP2024518735A (ja) * 2021-04-23 2024-05-02 アストラゼネカ・アクチエボラーグ 抗ｉ型ｉｎｆ受容体抗体アニフロルマブによるループス腎炎の治療
JP7484027B2 (ja) 2021-04-23 2024-05-15 アストラゼネカ・アクチエボラーグ 皮下注射のための抗ｉｆｎａｒ１投薬計画
JP7746407B2 (ja) 2021-04-23 2025-09-30 アストラゼネカ・アクチエボラーグ 抗ｉ型ｉｎｆ受容体抗体アニフロルマブによるループス腎炎の治療

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KR20210130270A (ko) 2021-10-29
KR102185237B9 (ko) 2021-08-06
CA2876636A1 (en) 2013-12-19
CN111494624A (zh) 2020-08-07
JP7123225B2 (ja) 2022-08-22
KR102320059B1 (ko) 2021-11-01
AU2020204613A1 (en) 2020-07-30
AU2018206851A1 (en) 2018-08-09
US20150158949A1 (en) 2015-06-11
EP2861621A1 (en) 2015-04-22
AU2020204613B2 (en) 2021-10-07
AU2018206851C1 (en) 2021-11-25
JP6814238B2 (ja) 2021-01-13
CN104603152A (zh) 2015-05-06
KR20200133395A (ko) 2020-11-27
AU2013274389A1 (en) 2015-01-22
JP2018065845A (ja) 2018-04-26
HK1209758A1 (en) 2016-04-08
US9493570B2 (en) 2016-11-15
CA2876636C (en) 2022-09-13
JP2019112429A (ja) 2019-07-11
KR102185237B1 (ko) 2020-12-02
JP2021167336A (ja) 2021-10-21
KR20150035825A (ko) 2015-04-07
JP2021042208A (ja) 2021-03-18
WO2013188494A1 (en) 2013-12-19
AU2018206851B2 (en) 2020-07-30
EP2861621A4 (en) 2016-01-20
CN108310375A (zh) 2018-07-24

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