JP2015520175A5 - - Google Patents
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- Publication number
- JP2015520175A5 JP2015520175A5 JP2015515352A JP2015515352A JP2015520175A5 JP 2015520175 A5 JP2015520175 A5 JP 2015520175A5 JP 2015515352 A JP2015515352 A JP 2015515352A JP 2015515352 A JP2015515352 A JP 2015515352A JP 2015520175 A5 JP2015520175 A5 JP 2015520175A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- antagonist
- polynucleotide
- subject
- virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000427 antigen Substances 0.000 claims 40
- 102000036639 antigens Human genes 0.000 claims 40
- 108091007433 antigens Proteins 0.000 claims 39
- 239000003814 drug Substances 0.000 claims 30
- 102000040430 polynucleotide Human genes 0.000 claims 23
- 108091033319 polynucleotide Proteins 0.000 claims 23
- 239000002157 polynucleotide Substances 0.000 claims 23
- 102000010787 Interleukin-4 Receptors Human genes 0.000 claims 21
- 108010038486 Interleukin-4 Receptors Proteins 0.000 claims 21
- 241000700605 Viruses Species 0.000 claims 17
- 239000005557 antagonist Substances 0.000 claims 17
- 229940079593 drug Drugs 0.000 claims 17
- 239000003795 chemical substances by application Substances 0.000 claims 10
- 230000035772 mutation Effects 0.000 claims 8
- 230000037430 deletion Effects 0.000 claims 6
- 238000012217 deletion Methods 0.000 claims 6
- 241000725303 Human immunodeficiency virus Species 0.000 claims 5
- 238000004519 manufacturing process Methods 0.000 claims 5
- 108090000978 Interleukin-4 Proteins 0.000 claims 4
- 230000002238 attenuated effect Effects 0.000 claims 4
- 239000012634 fragment Substances 0.000 claims 4
- 101710177291 Gag polyprotein Proteins 0.000 claims 3
- 210000001744 T-lymphocyte Anatomy 0.000 claims 3
- 108010078428 env Gene Products Proteins 0.000 claims 3
- 210000002865 immune cell Anatomy 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 108010089520 pol Gene Products Proteins 0.000 claims 3
- 230000037452 priming Effects 0.000 claims 3
- 241000178270 Canarypox virus Species 0.000 claims 2
- 241000700662 Fowlpox virus Species 0.000 claims 2
- 101001002709 Homo sapiens Interleukin-4 Proteins 0.000 claims 2
- 229940123418 Interleukin 4 receptor antagonist Drugs 0.000 claims 2
- 102000012347 Interleukin-4 Receptor alpha Subunit Human genes 0.000 claims 2
- 108010061858 Interleukin-4 Receptor alpha Subunit Proteins 0.000 claims 2
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 2
- 241000700618 Vaccinia virus Species 0.000 claims 2
- 206010046865 Vaccinia virus infection Diseases 0.000 claims 2
- 230000000890 antigenic effect Effects 0.000 claims 2
- 210000003719 b-lymphocyte Anatomy 0.000 claims 2
- 230000000903 blocking effect Effects 0.000 claims 2
- 102000055229 human IL4 Human genes 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 230000011664 signaling Effects 0.000 claims 2
- 241000701161 unidentified adenovirus Species 0.000 claims 2
- 208000007089 vaccinia Diseases 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 108010083359 Antigen Receptors Proteins 0.000 claims 1
- 238000001647 drug administration Methods 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 230000004083 survival effect Effects 0.000 claims 1
- 230000001052 transient effect Effects 0.000 claims 1
- 238000002255 vaccination Methods 0.000 claims 1
- 230000009385 viral infection Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2012902345 | 2012-06-05 | ||
| AU2012902345A AU2012902345A0 (en) | 2012-06-05 | Vaccination with Interleukin-4 Antagonists | |
| PCT/AU2013/000589 WO2013181696A1 (en) | 2012-06-05 | 2013-06-05 | Vaccination with interleukin-4 antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015520175A JP2015520175A (ja) | 2015-07-16 |
| JP2015520175A5 true JP2015520175A5 (cg-RX-API-DMAC7.html) | 2016-07-21 |
Family
ID=49711200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015515352A Pending JP2015520175A (ja) | 2012-06-05 | 2013-06-05 | インターロイキン−４アンタゴニストを伴うワクチン接種 |
Country Status (15)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109069625A (zh) * | 2016-02-19 | 2018-12-21 | 瑞泽恩制药公司 | 通过施用il-4r拮抗剂来增强疫苗功效的方法 |
| CN113527485B (zh) | 2020-04-17 | 2024-11-15 | 湖南麦济生物技术股份有限公司 | 抗人白细胞介素-4受体α抗体及其制备方法和应用 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5505941A (en) | 1981-12-24 | 1996-04-09 | Health Research, Inc. | Recombinant avipox virus and method to induce an immune response |
| US7045313B1 (en) | 1982-11-30 | 2006-05-16 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant vaccinia virus containing a chimeric gene having foreign DNA flanked by vaccinia regulatory DNA |
| US5219740A (en) | 1987-02-13 | 1993-06-15 | Fred Hutchinson Cancer Research Center | Retroviral gene transfer into diploid fibroblasts for gene therapy |
| HU212924B (en) | 1989-05-25 | 1996-12-30 | Chiron Corp | Adjuvant formulation comprising a submicron oil droplet emulsion |
| MY109299A (en) | 1990-08-15 | 1996-12-31 | Virogenetics Corp | Recombinant pox virus encoding flaviviral structural proteins |
| US5173414A (en) | 1990-10-30 | 1992-12-22 | Applied Immune Sciences, Inc. | Production of recombinant adeno-associated virus vectors |
| JP3282188B2 (ja) | 1991-06-27 | 2002-05-13 | 日本電気株式会社 | 半導体メモリ装置 |
| US5383851A (en) | 1992-07-24 | 1995-01-24 | Bioject Inc. | Needleless hypodermic injection device |
| EP0692532B1 (en) | 1993-03-31 | 2004-09-01 | Nippon Zeon Co., Ltd. | Novel polypeptide, dna coding for said polypeptide, recombinant vector containing said dna, recombinant virus prepared using said vector, and use thereof |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| CA2158733C (en) | 1994-01-21 | 2007-01-16 | Dennis E. Mccabe | Gas driven gene delivery instrument |
| GB9502879D0 (en) | 1995-02-14 | 1995-04-05 | Oxford Biosciences Ltd | Particle delivery |
| US6265387B1 (en) | 1995-10-11 | 2001-07-24 | Mirus, Inc. | Process of delivering naked DNA into a hepatocyte via bile duct |
| US6458560B1 (en) | 1996-04-05 | 2002-10-01 | Chiron Corporation | Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis |
| US6451592B1 (en) | 1996-04-05 | 2002-09-17 | Chiron Corporation | Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis |
| JP2000514290A (ja) | 1996-07-01 | 2000-10-31 | ローヌ―プーラン・ロレ・エス・アー | 組換えアデノウイルスの製造方法 |
| US5993412A (en) | 1997-05-19 | 1999-11-30 | Bioject, Inc. | Injection apparatus |
| EP1042494A1 (en) | 1997-12-23 | 2000-10-11 | Introgene B.V. | Adeno-associated virus and adenovirus chimeric recombinant viruses useful for the integration of foreign genetic information into the chromosomal dna of target cells |
| US7922709B2 (en) | 1998-07-13 | 2011-04-12 | Genetronics, Inc. | Enhanced delivery of naked DNA to skin by non-invasive in vivo electroporation |
| US6972013B1 (en) | 1998-07-13 | 2005-12-06 | Genetronics, Inc. | Enhanced delivery of naked DNA to skin by non-invasive in vivo electroporation |
| US7608273B2 (en) | 1998-08-12 | 2009-10-27 | University Of Western Ontario | Recombinant lentivirus encoding modified GP 120 signal sequences |
| AT408615B (de) | 1998-09-15 | 2002-01-25 | Immuno Ag | Neue influenzavirus-impfstoffzusammensetzung |
| JP4693244B2 (ja) | 1999-03-18 | 2011-06-01 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | 組換えアデノ随伴ウイルスのヘルパー無しの生産のための組成物および方法 |
| ATE368122T1 (de) | 1999-04-29 | 2007-08-15 | Cell Genesys Inc | Verfahren und mittel für die herstellung von sicheren rekombinanten lentiviralen vektoren mit hohem titer |
| GB9923176D0 (en) | 1999-09-30 | 1999-12-01 | Smithkline Beecham Biolog | Novel composition |
| WO2001083797A2 (en) | 2000-04-28 | 2001-11-08 | Avigen, Inc. | Polynucleotides for use in recombinant adeno-associated virus virion production |
| EP1407033B1 (en) | 2002-05-16 | 2006-01-11 | Bavarian Nordic A/S | Intergenic regions as insertion sites in the genome of modified vaccinia virus ankara (mva) |
| WO2004028563A1 (en) | 2002-09-27 | 2004-04-08 | Genexine Inc. | A vaccine enhancing the protective immunity to hepatitis c virus using plasmid dna and recombinant adenovirus |
| WO2007121194A1 (en) * | 2006-04-10 | 2007-10-25 | The Regents Of The University Of California | Immunostimulatory recombinant intracellular pathogen immunogenic compositions and methods of use |
| WO2006012221A2 (en) | 2004-06-25 | 2006-02-02 | The Regents Of The University Of California | Target cell-specific short interfering rna and methods of use thereof |
| WO2006135436A2 (en) | 2004-10-22 | 2006-12-21 | University Of Florida Research Foundation, Inc. | Inhibition of gene expression and therapeutic uses thereof |
| US8048404B1 (en) | 2005-01-04 | 2011-11-01 | Gp Medical, Inc. | Pharmaceutical composition of nanoparticles for protein drug delivery |
| US7611690B2 (en) | 2005-01-04 | 2009-11-03 | Gp Medical, Inc. | Nanoparticles for protein drug delivery |
| US7541046B1 (en) | 2005-01-04 | 2009-06-02 | Gp Medical, Inc. | Nanoparticles for protein drug delivery |
| BRPI0609949A2 (pt) | 2005-04-24 | 2010-05-11 | Acambis Inc | flavivìrus recombinante, seu uso na preparação de vacina, composição farmacêutica compreendendo o mesmo, molécula de ácido nucléico e método para atenuar candidato a vacina de flavivìrus |
| AR054822A1 (es) | 2005-07-07 | 2007-07-18 | Sanofi Pasteur | Emulsion inmuno adyuvante |
| MX2008008968A (es) * | 2006-01-11 | 2008-09-10 | Aerovance Inc | Metodos y composiciones para tratar asma en primates humanos y no humanos. |
| CN101977935A (zh) * | 2007-04-23 | 2011-02-16 | 惠氏公司 | 用于治疗和监测il-13相关病症的方法和组合物 |
| EP2414520A2 (en) * | 2009-03-31 | 2012-02-08 | Altair Therapeutics, Inc. | Methods of modulating an immune response to a viral infection |
| AU2010269120B2 (en) * | 2009-07-06 | 2015-09-24 | The Australian National University | Immunomodulating compositions comprising interleukin 13 inhibitors and uses therefor |
-
2013
- 2013-06-05 US US14/405,704 patent/US20150150963A1/en not_active Abandoned
- 2013-06-05 SG SG11201408101TA patent/SG11201408101TA/en unknown
- 2013-06-05 JP JP2015515352A patent/JP2015520175A/ja active Pending
- 2013-06-05 IN IN10408DEN2014 patent/IN2014DN10408A/en unknown
- 2013-06-05 EP EP13800233.2A patent/EP2854837A4/en not_active Withdrawn
- 2013-06-05 HK HK15103819.6A patent/HK1203358A1/xx unknown
- 2013-06-05 WO PCT/AU2013/000589 patent/WO2013181696A1/en not_active Ceased
- 2013-06-05 BR BR112014030436A patent/BR112014030436A2/pt not_active IP Right Cessation
- 2013-06-05 EP EP19150395.2A patent/EP3530283A1/en not_active Withdrawn
- 2013-06-05 NZ NZ702721A patent/NZ702721A/en not_active IP Right Cessation
- 2013-06-05 KR KR20147037109A patent/KR20150021088A/ko not_active Withdrawn
- 2013-06-05 AU AU2013271338A patent/AU2013271338B2/en not_active Ceased
- 2013-06-05 CN CN201380040156.6A patent/CN104717971A/zh active Pending
- 2013-06-05 CA CA2875683A patent/CA2875683A1/en not_active Abandoned
-
2014
- 2014-12-04 IL IL236092A patent/IL236092A0/en unknown
- 2014-12-10 ZA ZA2014/09076A patent/ZA201409076B/en unknown