JP2015520161A5 - - Google Patents

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Publication number
JP2015520161A5
JP2015520161A5 JP2015512644A JP2015512644A JP2015520161A5 JP 2015520161 A5 JP2015520161 A5 JP 2015520161A5 JP 2015512644 A JP2015512644 A JP 2015512644A JP 2015512644 A JP2015512644 A JP 2015512644A JP 2015520161 A5 JP2015520161 A5 JP 2015520161A5
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JP
Japan
Prior art keywords
composition
mammal
nucleic acid
aav
vector
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JP2015512644A
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English (en)
Japanese (ja)
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JP6469000B2 (ja
JP2015520161A (ja
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Priority claimed from PCT/US2013/031725 external-priority patent/WO2013172964A1/en
Publication of JP2015520161A publication Critical patent/JP2015520161A/ja
Publication of JP2015520161A5 publication Critical patent/JP2015520161A5/ja
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Publication of JP6469000B2 publication Critical patent/JP6469000B2/ja
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JP2015512644A 2012-05-18 2013-03-14 アミロイドの沈着を処置するための方法および組成物 Active JP6469000B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261648801P 2012-05-18 2012-05-18
US61/648,801 2012-05-18
PCT/US2013/031725 WO2013172964A1 (en) 2012-05-18 2013-03-14 Methods and compositions for treating amyloid deposits

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018207331A Division JP2019031564A (ja) 2012-05-18 2018-11-02 アミロイドの沈着を処置するための方法および組成物

Publications (3)

Publication Number Publication Date
JP2015520161A JP2015520161A (ja) 2015-07-16
JP2015520161A5 true JP2015520161A5 (enExample) 2016-05-12
JP6469000B2 JP6469000B2 (ja) 2019-02-13

Family

ID=49584137

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015512644A Active JP6469000B2 (ja) 2012-05-18 2013-03-14 アミロイドの沈着を処置するための方法および組成物
JP2018207331A Pending JP2019031564A (ja) 2012-05-18 2018-11-02 アミロイドの沈着を処置するための方法および組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2018207331A Pending JP2019031564A (ja) 2012-05-18 2018-11-02 アミロイドの沈着を処置するための方法および組成物

Country Status (12)

Country Link
US (1) US20150183850A1 (enExample)
EP (1) EP2850195B1 (enExample)
JP (2) JP6469000B2 (enExample)
CN (2) CN104540952A (enExample)
AU (1) AU2013263346B2 (enExample)
BR (1) BR112014028666B1 (enExample)
CA (1) CA2873890C (enExample)
ES (1) ES2786078T3 (enExample)
HK (1) HK1207109A1 (enExample)
IN (1) IN2014KN02672A (enExample)
RU (1) RU2673484C2 (enExample)
WO (1) WO2013172964A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112375760A (zh) 2014-11-14 2021-02-19 沃雅戈治疗公司 调节性多核苷酸
US11027024B2 (en) 2015-05-29 2021-06-08 University Of Iowa Research Foundation Methods of delivery of transgenes for treating brain diseases
EP3307391A1 (en) * 2015-06-12 2018-04-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical composition for the treatment of alzheimer's disease
EP3444344A4 (en) * 2016-04-14 2020-02-19 TAO Health Life Pharma Co., Ltd. AMYLOSPHEROID TYPE STRUCTURE (ASPD) AND PHARMACEUTICAL COMPOSITION
CN117904112A (zh) 2016-05-18 2024-04-19 沃雅戈治疗公司 调节性多核苷酸
CA3032697A1 (en) * 2016-08-03 2018-02-08 University Of South Florida Reelin compositions for treatment of neurological disorders
WO2018045347A1 (en) * 2016-09-02 2018-03-08 Spark Therapeutics, Inc. Methods and vectors for treating cns disorders
EP3309550A1 (en) * 2016-10-12 2018-04-18 sphingotec GmbH Method for the detection of apolipoprotein e4
MX2020003965A (es) 2017-10-03 2020-10-05 Prevail Therapeutics Inc Terapias genicas para los trastornos lisosomales.
MX2020004005A (es) 2017-10-03 2020-10-05 Prevail Therapeutics Inc Terapias genicas para los trastornos lisosomales.
JP7616995B2 (ja) * 2018-11-28 2025-01-17 プリベイル セラピューティクス,インコーポレーテッド 神経変性疾患のための遺伝子治療
KR20220082050A (ko) * 2019-10-16 2022-06-16 코넬 유니버시티 알츠하이머병에 대한 유전자 요법
IL296494A (en) * 2020-03-31 2022-11-01 Nuo Beta Pharmarceutical Tech Shanghai Co Ltd Deuterated oxophenylarsine compound and use thereof
CN116670291A (zh) * 2020-11-25 2023-08-29 普利维尔治疗公司 用于神经退行性疾病的基因疗法
WO2023108507A1 (en) * 2021-12-15 2023-06-22 National Institute Of Biological Sciences, Beijing Recombinant aav vectors and use thereof
CN116063405B (zh) * 2022-09-27 2025-08-29 广州译码基因科技有限公司 可提高AAV病毒包装能力的衣壳蛋白突变体MutC及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589154A (en) * 1994-11-22 1996-12-31 Rutgers, The State University Of New Jersey Methods for the prevention or treatment of vascular hemorrhaging and Alzheimer's disease
US6436996B1 (en) * 1997-09-30 2002-08-20 Duke University Modulation of nitric oxide production
US6855314B1 (en) 2000-03-22 2005-02-15 The United States Of America As Represented By The Department Of Health And Human Services AAV5 vector for transducing brain cells and lung cells
US6468524B1 (en) 2000-03-22 2002-10-22 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services AAV4 vector and uses thereof
GB0322645D0 (en) * 2003-09-26 2003-10-29 Melacure Therapeutics Ab Use of antisecretory factor peptides
EP1828390B1 (en) * 2004-12-15 2012-06-13 The University Of North Carolina At Chapel Hill Chimeric vectors
DK1879623T3 (da) * 2005-05-02 2012-12-17 Genzyme Corp Genterapi til rygmarvssygdomme
CN102886052B (zh) * 2006-09-14 2014-07-30 迈德詹尼克斯医疗以色列有限公司 长效药物制剂
CA2684946C (en) * 2007-05-16 2015-03-31 The Brigham And Women's Hospital, Inc. Treatment of synucleinopathies
EP2561075B1 (en) * 2010-04-23 2018-06-27 University of Massachusetts Aav-based treatment of cholesterol-related disorders

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