JP2015520161A5 - - Google Patents

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Publication number
JP2015520161A5
JP2015520161A5 JP2015512644A JP2015512644A JP2015520161A5 JP 2015520161 A5 JP2015520161 A5 JP 2015520161A5 JP 2015512644 A JP2015512644 A JP 2015512644A JP 2015512644 A JP2015512644 A JP 2015512644A JP 2015520161 A5 JP2015520161 A5 JP 2015520161A5
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JP
Japan
Prior art keywords
composition
mammal
nucleic acid
aav
vector
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Application number
JP2015512644A
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English (en)
Japanese (ja)
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JP2015520161A (ja
JP6469000B2 (ja
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Priority claimed from PCT/US2013/031725 external-priority patent/WO2013172964A1/en
Publication of JP2015520161A publication Critical patent/JP2015520161A/ja
Publication of JP2015520161A5 publication Critical patent/JP2015520161A5/ja
Application granted granted Critical
Publication of JP6469000B2 publication Critical patent/JP6469000B2/ja
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JP2015512644A 2012-05-18 2013-03-14 アミロイドの沈着を処置するための方法および組成物 Active JP6469000B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261648801P 2012-05-18 2012-05-18
US61/648,801 2012-05-18
PCT/US2013/031725 WO2013172964A1 (en) 2012-05-18 2013-03-14 Methods and compositions for treating amyloid deposits

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018207331A Division JP2019031564A (ja) 2012-05-18 2018-11-02 アミロイドの沈着を処置するための方法および組成物

Publications (3)

Publication Number Publication Date
JP2015520161A JP2015520161A (ja) 2015-07-16
JP2015520161A5 true JP2015520161A5 (enExample) 2016-05-12
JP6469000B2 JP6469000B2 (ja) 2019-02-13

Family

ID=49584137

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015512644A Active JP6469000B2 (ja) 2012-05-18 2013-03-14 アミロイドの沈着を処置するための方法および組成物
JP2018207331A Pending JP2019031564A (ja) 2012-05-18 2018-11-02 アミロイドの沈着を処置するための方法および組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2018207331A Pending JP2019031564A (ja) 2012-05-18 2018-11-02 アミロイドの沈着を処置するための方法および組成物

Country Status (12)

Country Link
US (1) US20150183850A1 (enExample)
EP (1) EP2850195B1 (enExample)
JP (2) JP6469000B2 (enExample)
CN (2) CN112574964A (enExample)
AU (1) AU2013263346B2 (enExample)
BR (1) BR112014028666B1 (enExample)
CA (1) CA2873890C (enExample)
ES (1) ES2786078T3 (enExample)
HK (1) HK1207109A1 (enExample)
IN (1) IN2014KN02672A (enExample)
RU (1) RU2673484C2 (enExample)
WO (1) WO2013172964A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112410338A (zh) 2014-11-14 2021-02-26 沃雅戈治疗公司 调节性多核苷酸
US11027024B2 (en) 2015-05-29 2021-06-08 University Of Iowa Research Foundation Methods of delivery of transgenes for treating brain diseases
WO2016198627A1 (en) * 2015-06-12 2016-12-15 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical composition for the treatment of alzheimer's disease
WO2017179646A1 (ja) * 2016-04-14 2017-10-19 Taoヘルスライフファーマ株式会社 アミロスフェロイド(aspd)様構造体及び医薬組成物
SG11201809699XA (en) 2016-05-18 2018-12-28 Voyager Therapeutics Inc Modulatory polynucleotides
CN109715194B (zh) * 2016-08-03 2024-06-11 南佛罗里达大学 用于治疗神经障碍的颤蛋白组合物
BR112019004353A2 (pt) * 2016-09-02 2019-05-28 Spark Therapeutics, Inc. métodos e vetores para tratar distúrbios do cns
EP3309550A1 (en) * 2016-10-12 2018-04-18 sphingotec GmbH Method for the detection of apolipoprotein e4
CN112553210B (zh) 2017-10-03 2024-09-24 普利维尔治疗公司 用于溶酶体障碍的基因疗法
CA3078501A1 (en) 2017-10-03 2019-04-11 Prevail Therapeutics, Inc. Gene therapies for lysosomal disorders
BR112021010234A2 (pt) * 2018-11-28 2021-08-24 Prevail Therapeutics, Inc. Terapias de gene para doença neurodegenerativa
US20230405148A1 (en) * 2019-10-16 2023-12-21 Cornell University Gene therapy for alzheimer's disease
IL293116A (en) 2019-11-25 2022-07-01 Univ Cornell apoe gene therapy
CA3171783A1 (en) * 2020-03-31 2021-10-07 Fude HUANG Deuterated oxophenylarsine compound and use thereof
JP2023551254A (ja) * 2020-11-25 2023-12-07 プリベイル セラピューティクス,インコーポレーテッド 神経変性疾患のための遺伝子治療
WO2023108507A1 (en) * 2021-12-15 2023-06-22 National Institute Of Biological Sciences, Beijing Recombinant aav vectors and use thereof
CN116063405B (zh) * 2022-09-27 2025-08-29 广州译码基因科技有限公司 可提高AAV病毒包装能力的衣壳蛋白突变体MutC及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589154A (en) * 1994-11-22 1996-12-31 Rutgers, The State University Of New Jersey Methods for the prevention or treatment of vascular hemorrhaging and Alzheimer's disease
US6436996B1 (en) * 1997-09-30 2002-08-20 Duke University Modulation of nitric oxide production
US6855314B1 (en) 2000-03-22 2005-02-15 The United States Of America As Represented By The Department Of Health And Human Services AAV5 vector for transducing brain cells and lung cells
US6468524B1 (en) * 2000-03-22 2002-10-22 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services AAV4 vector and uses thereof
GB0322645D0 (en) * 2003-09-26 2003-10-29 Melacure Therapeutics Ab Use of antisecretory factor peptides
AU2005316476A1 (en) * 2004-12-15 2006-06-22 University Of Florida Research Foundation, Inc. Chimeric vectors
AU2006242129A1 (en) * 2005-05-02 2006-11-09 Genzyme Corporation Gene therapy for spinal cord disorders
WO2008033375A2 (en) * 2006-09-14 2008-03-20 Medgenics Ltd. Long lasting drug formulations
US8454954B2 (en) * 2007-05-16 2013-06-04 The Brigham And Women's Hospital, Inc. Treatment of synucleinopathies
US9272053B2 (en) * 2010-04-23 2016-03-01 University Of Massachusetts AAV-based treatment of cholesterol-related disorders

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