JP2015518827A5 - - Google Patents
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- JP2015518827A5 JP2015518827A5 JP2015512727A JP2015512727A JP2015518827A5 JP 2015518827 A5 JP2015518827 A5 JP 2015518827A5 JP 2015512727 A JP2015512727 A JP 2015512727A JP 2015512727 A JP2015512727 A JP 2015512727A JP 2015518827 A5 JP2015518827 A5 JP 2015518827A5
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- JP
- Japan
- Prior art keywords
- seq
- sequence number
- sequence
- variable region
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261648391P | 2012-05-17 | 2012-05-17 | |
| US61/648,391 | 2012-05-17 | ||
| PCT/US2013/040827 WO2013173255A2 (en) | 2012-05-17 | 2013-05-13 | Antigen binding proteins that bind egfr |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015518827A JP2015518827A (ja) | 2015-07-06 |
| JP2015518827A5 true JP2015518827A5 (https=) | 2016-06-30 |
| JP6441792B2 JP6441792B2 (ja) | 2018-12-19 |
Family
ID=49581478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015512727A Expired - Fee Related JP6441792B2 (ja) | 2012-05-17 | 2013-05-13 | Egfrに結合する抗原結合蛋白質 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9944707B2 (https=) |
| EP (1) | EP2850105A4 (https=) |
| JP (1) | JP6441792B2 (https=) |
| CN (1) | CN104918956A (https=) |
| CA (1) | CA2872018A1 (https=) |
| HK (1) | HK1208474A1 (https=) |
| WO (1) | WO2013173255A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10100118B2 (en) | 2015-04-08 | 2018-10-16 | Sorrento Therapeutics, Inc. | Antibody therapeutics that bind CD123 |
| EP3280442A4 (en) | 2015-04-08 | 2018-10-31 | Sorrento Therapeutics, Inc. | Antibody therapeutics that bind cd123 |
| KR20180086502A (ko) * | 2015-12-16 | 2018-07-31 | 머크 샤프 앤드 돔 코포레이션 | 항-lag3 항체 및 항원-결합 단편 |
| TWI736575B (zh) | 2016-01-22 | 2021-08-21 | 美商默沙東藥廠 | 抗凝固因子xi抗體 |
| SI3449939T1 (sl) * | 2016-04-27 | 2022-06-30 | Green Cross Corporation | Farmacevtski sestavek za zaviranje metastaz pri raku, ki kot učinkovino obsega protitelo, ki se specifično veže na receptor za epidermalni rastni faktor |
| IL263272B2 (en) | 2016-06-14 | 2025-07-01 | Merck Sharp & Dohme | Antibodies to coagulation factor xi |
| WO2020247290A1 (en) * | 2019-06-04 | 2020-12-10 | Academia Sinica | Ligands targed to epidermal growth factor receptors and compositions for use in treating tumors |
| US20230001008A1 (en) * | 2019-08-20 | 2023-01-05 | Kumquat Biosciences Inc. | Compositions and methods for targeting cellular molecules |
| EP4347643A4 (en) * | 2021-05-27 | 2025-09-17 | Us Gov Veterans Affairs | HUMAN MONOCLONAL ANTIBODIES SPECIFIC TO STREPTOLYSIN O AND METHODS OF USE |
| CN119053621A (zh) * | 2022-02-04 | 2024-11-29 | 维硕公司 | 结合b7-h3的抗原结合蛋白 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ292061B6 (cs) | 1994-03-17 | 2003-07-16 | Merck Patent Gmbh | Jednořetězcové fragmenty protilátek a protilátky proti receptoru epidermálního růstového faktoru, způsob jejich přípravy a farmaceutický prostředek, který je obsahuje |
| EP1500329B1 (en) | 1996-12-03 | 2012-03-21 | Amgen Fremont Inc. | Human antibodies that specifically bind human TNF alpha |
| US6235883B1 (en) * | 1997-05-05 | 2001-05-22 | Abgenix, Inc. | Human monoclonal antibodies to epidermal growth factor receptor |
| US20020173629A1 (en) | 1997-05-05 | 2002-11-21 | Aya Jakobovits | Human monoclonal antibodies to epidermal growth factor receptor |
| TR200200472T2 (tr) | 1999-08-27 | 2002-06-21 | Genentech, Inc. | Anti-Erb B2 antikorları ile tedavi için dozajlar |
| US7595378B2 (en) * | 2001-06-13 | 2009-09-29 | Genmab A/S | Human monoclonal antibodies to epidermal growth factor receptor (EGFR) |
| NZ530212A (en) | 2001-06-13 | 2006-09-29 | Genmab As | An isolated human monoclonal antibody that binds to human epidermal growth factor receptor (EGFR) |
| CN101233155B (zh) * | 2004-03-19 | 2013-06-19 | 英克隆有限责任公司 | 人抗表皮生长因子受体抗体 |
| EP2332990A1 (en) | 2004-03-19 | 2011-06-15 | Imclone LLC | Human anti-epidermal growth factor receptor antibody |
| AU2006211037B2 (en) * | 2005-02-07 | 2012-05-24 | Roche Glycart Ag | Antigen binding molecules that bind EGFR, vectors encoding same, and uses thereof |
| US20060216288A1 (en) | 2005-03-22 | 2006-09-28 | Amgen Inc | Combinations for the treatment of cancer |
| WO2007058823A2 (en) | 2005-11-12 | 2007-05-24 | Eli Lilly And Company | Anti-egfr antibodies |
| US20090017050A1 (en) | 2007-07-13 | 2009-01-15 | Ventana Medical Systems, Inc. | Egfr antigen-binding molecules and uses thereof |
| AU2009296297A1 (en) | 2008-09-26 | 2010-04-01 | Roche Glycart Ag | Bispecific anti-EGFR/anti-IGF-1R antibodies |
| JPWO2010087425A1 (ja) | 2009-01-30 | 2012-08-02 | 国立大学法人京都大学 | 前立腺癌の進行抑制剤および進行抑制方法 |
| CA2754646A1 (en) | 2009-03-31 | 2010-10-07 | Roche Glycart Ag | Treatment of cancer with a humanized anti-egfr igg1 antibody and irinotecan |
| TW201122101A (en) | 2009-10-28 | 2011-07-01 | Facet Biotech Corp | Anti-EGFR antibodies and their uses |
| JP5818003B2 (ja) | 2009-11-18 | 2015-11-18 | 国立大学法人東北大学 | ヒト型化抗egfr抗体可変領域の高機能性変異体 |
| WO2011156617A2 (en) | 2010-06-09 | 2011-12-15 | Aveo Pharmaceuticals, Inc. | Anti-egfr antibodies |
| CN103298489A (zh) * | 2010-10-29 | 2013-09-11 | 伊缪诺金公司 | 新型egfr结合分子及其免疫偶联物 |
| US8691231B2 (en) | 2011-06-03 | 2014-04-08 | Merrimack Pharmaceuticals, Inc. | Methods of treatment of tumors expressing predominantly high affinity EGFR ligands or tumors expressing predominantly low affinity EGFR ligands with monoclonal and oligoclonal anti-EGFR antibodies |
| TWI443108B (zh) | 2011-12-28 | 2014-07-01 | Ind Tech Res Inst | 抗人類表皮生長因子受體抗體及其應用 |
-
2013
- 2013-05-13 WO PCT/US2013/040827 patent/WO2013173255A2/en not_active Ceased
- 2013-05-13 JP JP2015512727A patent/JP6441792B2/ja not_active Expired - Fee Related
- 2013-05-13 US US13/893,312 patent/US9944707B2/en active Active
- 2013-05-13 HK HK15109023.5A patent/HK1208474A1/xx unknown
- 2013-05-13 EP EP13790813.3A patent/EP2850105A4/en not_active Withdrawn
- 2013-05-13 CN CN201380038496.5A patent/CN104918956A/zh active Pending
- 2013-05-13 CA CA2872018A patent/CA2872018A1/en not_active Abandoned
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