JP2015516156A5 - - Google Patents
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- Publication number
- JP2015516156A5 JP2015516156A5 JP2015509008A JP2015509008A JP2015516156A5 JP 2015516156 A5 JP2015516156 A5 JP 2015516156A5 JP 2015509008 A JP2015509008 A JP 2015509008A JP 2015509008 A JP2015509008 A JP 2015509008A JP 2015516156 A5 JP2015516156 A5 JP 2015516156A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- cells
- isolated
- cell
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108090000623 proteins and genes Proteins 0.000 claims 27
- 102000004169 proteins and genes Human genes 0.000 claims 21
- 210000003719 b-lymphocyte Anatomy 0.000 claims 15
- 241000701044 Human gammaherpesvirus 4 Species 0.000 claims 12
- 239000003795 chemical substances by application Substances 0.000 claims 8
- 102000003814 Interleukin-10 Human genes 0.000 claims 7
- 108090000174 Interleukin-10 Proteins 0.000 claims 7
- 229940076144 interleukin-10 Drugs 0.000 claims 7
- 238000000034 method Methods 0.000 claims 7
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 claims 6
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 claims 6
- 230000001939 inductive effect Effects 0.000 claims 5
- 241000124008 Mammalia Species 0.000 claims 3
- 239000003112 inhibitor Substances 0.000 claims 3
- 210000004698 lymphocyte Anatomy 0.000 claims 3
- 102000015696 Interleukins Human genes 0.000 claims 2
- 108010063738 Interleukins Proteins 0.000 claims 2
- 230000005784 autoimmunity Effects 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 210000002707 regulatory b cell Anatomy 0.000 claims 2
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 206010039710 Scleroderma Diseases 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 206010046851 Uveitis Diseases 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261637915P | 2012-04-25 | 2012-04-25 | |
| US61/637,915 | 2012-04-25 | ||
| PCT/US2013/036175 WO2013162905A1 (en) | 2012-04-25 | 2013-04-11 | Methods of producing and using regulatory b-cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015516156A JP2015516156A (ja) | 2015-06-11 |
| JP2015516156A5 true JP2015516156A5 (enExample) | 2016-05-19 |
| JP6258922B2 JP6258922B2 (ja) | 2018-01-10 |
Family
ID=48183014
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015509008A Active JP6258922B2 (ja) | 2012-04-25 | 2013-04-11 | 制御性ｂ細胞の製造及び使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9629897B2 (enExample) |
| EP (1) | EP2841562B1 (enExample) |
| JP (1) | JP6258922B2 (enExample) |
| AU (1) | AU2013252771B2 (enExample) |
| CA (1) | CA2871499C (enExample) |
| WO (1) | WO2013162905A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015526520A (ja) * | 2012-08-31 | 2015-09-10 | プリンシピア バイオファーマ インコーポレイテッド | Ｉｔｋ阻害剤としてのベンズイミダゾール誘導体 |
| WO2018013897A1 (en) * | 2016-07-15 | 2018-01-18 | Board Of Regents, The University Of Texas System | Regulatory b cells and uses thereof |
| GB201707238D0 (en) | 2017-05-05 | 2017-06-21 | Univ Oxford Innovation Ltd | Composition |
| EP4302768A3 (en) * | 2017-06-22 | 2024-05-01 | Board Of Regents, The University Of Texas System | Methods for producing regulatory immune cells and uses thereof |
| WO2019165447A1 (en) * | 2018-02-26 | 2019-08-29 | Claudia Zylberberg | Immune cell activation |
| CA3136551A1 (en) | 2019-04-12 | 2020-10-15 | Board Of Regents, The University Of Texas System | Methods for producing regulatory b cells and uses thereof |
| CA3143998A1 (en) | 2019-06-18 | 2020-12-24 | Charles E. EGWUAGU | Interleukin-27 producing b-cells and uses thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008500812A (ja) | 2004-03-18 | 2008-01-17 | ザ ユニバーシティー コート オブ ザ ユニバーシティー オブ グラスゴウ | 免疫抑制サイトカイン |
| AU2006261527B2 (en) | 2005-05-16 | 2012-11-22 | Prometic Pharma Smt Limited | Purine derivatives and their use for treatment of autoimmune diseases |
| WO2009131712A2 (en) * | 2008-04-25 | 2009-10-29 | Duke University Medical Center | Regulatory b cells and their uses |
| US8592364B2 (en) * | 2010-02-11 | 2013-11-26 | Ecole Polytechnique Federale de Lausanne (“EPFL”) | CCR7 ligand delivery and co-delivery in immunotherapy |
| WO2012082771A1 (en) * | 2010-12-13 | 2012-06-21 | The Board Of Trustees Of The Leland Stanford Junior University | Cardiac glycosides for treating autoimmune disease |
-
2013
- 2013-04-11 EP EP13718448.7A patent/EP2841562B1/en active Active
- 2013-04-11 JP JP2015509008A patent/JP6258922B2/ja active Active
- 2013-04-11 WO PCT/US2013/036175 patent/WO2013162905A1/en not_active Ceased
- 2013-04-11 CA CA2871499A patent/CA2871499C/en active Active
- 2013-04-11 AU AU2013252771A patent/AU2013252771B2/en active Active
- 2013-04-11 US US14/396,475 patent/US9629897B2/en active Active
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