JP2015514096A5 - - Google Patents
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- Publication number
- JP2015514096A5 JP2015514096A5 JP2015503646A JP2015503646A JP2015514096A5 JP 2015514096 A5 JP2015514096 A5 JP 2015514096A5 JP 2015503646 A JP2015503646 A JP 2015503646A JP 2015503646 A JP2015503646 A JP 2015503646A JP 2015514096 A5 JP2015514096 A5 JP 2015514096A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- body weight
- weeks
- neuregulin
- effective amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000037396 body weight Effects 0.000 claims description 220
- 102000014413 Neuregulin Human genes 0.000 claims description 115
- 108050003475 Neuregulin Proteins 0.000 claims description 115
- 208000010886 Peripheral nerve injury Diseases 0.000 claims description 38
- 210000005036 nerve Anatomy 0.000 claims description 30
- 206010028980 Neoplasm Diseases 0.000 claims description 18
- 210000000578 peripheral nerve Anatomy 0.000 claims description 17
- 238000001356 surgical procedure Methods 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 13
- 201000011510 cancer Diseases 0.000 claims description 12
- 210000003497 sciatic nerve Anatomy 0.000 claims description 9
- 208000016192 Demyelinating disease Diseases 0.000 claims description 7
- 206010012305 Demyelination Diseases 0.000 claims description 7
- 208000010228 Erectile Dysfunction Diseases 0.000 claims description 7
- 201000001881 impotence Diseases 0.000 claims description 7
- 210000001519 tissue Anatomy 0.000 claims description 6
- 206010006187 Breast cancer Diseases 0.000 claims description 3
- 208000026310 Breast neoplasm Diseases 0.000 claims description 3
- 206010060862 Prostate cancer Diseases 0.000 claims description 3
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims description 3
- 230000003187 abdominal effect Effects 0.000 claims description 3
- 238000012084 abdominal surgery Methods 0.000 claims description 3
- 238000010878 colorectal surgery Methods 0.000 claims description 3
- 238000002271 resection Methods 0.000 claims description 3
- 239000007787 solid Substances 0.000 claims description 3
- 208000004296 neuralgia Diseases 0.000 claims 2
- 208000021722 neuropathic pain Diseases 0.000 claims 2
- 230000035606 childbirth Effects 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 230000006698 induction Effects 0.000 description 2
- 230000000472 traumatic effect Effects 0.000 description 2
- 230000002045 lasting effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261618381P | 2012-03-30 | 2012-03-30 | |
| US61/618,381 | 2012-03-30 | ||
| US201261674060P | 2012-07-20 | 2012-07-20 | |
| US61/674,060 | 2012-07-20 | ||
| US201261693585P | 2012-08-27 | 2012-08-27 | |
| US201261693589P | 2012-08-27 | 2012-08-27 | |
| US61/693,589 | 2012-08-27 | ||
| US61/693,585 | 2012-08-27 | ||
| US201361785419P | 2013-03-14 | 2013-03-14 | |
| US61/785,419 | 2013-03-14 | ||
| PCT/US2013/034634 WO2013149163A1 (en) | 2012-03-30 | 2013-03-29 | Use of neuregulin to treat peripheral nerve injury |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017076415A Division JP2017149746A (ja) | 2012-03-30 | 2017-04-07 | 末梢神経損傷を処置するためのニューレグリンの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015514096A JP2015514096A (ja) | 2015-05-18 |
| JP2015514096A5 true JP2015514096A5 (enExample) | 2015-08-06 |
| JP6420233B2 JP6420233B2 (ja) | 2018-11-07 |
Family
ID=48128617
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015503646A Expired - Fee Related JP6420233B2 (ja) | 2012-03-30 | 2013-03-29 | 末梢神経損傷を処置するためのニューレグリンの使用 |
| JP2017076415A Pending JP2017149746A (ja) | 2012-03-30 | 2017-04-07 | 末梢神経損傷を処置するためのニューレグリンの使用 |
| JP2019070976A Pending JP2019131582A (ja) | 2012-03-30 | 2019-04-03 | 末梢神経損傷を処置するためのニューレグリンの使用 |
| JP2021004728A Active JP7108724B2 (ja) | 2012-03-30 | 2021-01-15 | 末梢神経損傷を処置するためのニューレグリンの使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017076415A Pending JP2017149746A (ja) | 2012-03-30 | 2017-04-07 | 末梢神経損傷を処置するためのニューレグリンの使用 |
| JP2019070976A Pending JP2019131582A (ja) | 2012-03-30 | 2019-04-03 | 末梢神経損傷を処置するためのニューレグリンの使用 |
| JP2021004728A Active JP7108724B2 (ja) | 2012-03-30 | 2021-01-15 | 末梢神経損傷を処置するためのニューレグリンの使用 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20150094263A1 (enExample) |
| EP (3) | EP2830645B1 (enExample) |
| JP (4) | JP6420233B2 (enExample) |
| CN (2) | CN104321072A (enExample) |
| AU (4) | AU2013237896B2 (enExample) |
| BR (1) | BR112014024308B1 (enExample) |
| CA (1) | CA2869070A1 (enExample) |
| DK (2) | DK3278811T3 (enExample) |
| ES (2) | ES2647917T3 (enExample) |
| IL (3) | IL288785B2 (enExample) |
| MX (1) | MX354598B (enExample) |
| NZ (1) | NZ700546A (enExample) |
| PL (2) | PL3278811T3 (enExample) |
| PT (2) | PT2830645T (enExample) |
| WO (1) | WO2013149163A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3338791T3 (da) | 2008-07-17 | 2019-12-16 | Acorda Therapeutics Inc | Terapeutisk dosering af en neuregulin i behandling eller profylaxis af hjertesvigt |
| PL3235504T3 (pl) | 2009-10-14 | 2020-03-31 | Acorda Therapeutics, Inc. | Zastosowanie neureguliny do leczenia uszkodzenia nerwu obwodowego |
| ITUB20155471A1 (it) * | 2015-11-11 | 2017-05-11 | Univ Degli Studi Di Torino | Coniugato della neuregulina 1 per il trattamento delle lesioni dei nervi periferici |
| IL294038A (en) * | 2015-12-04 | 2022-08-01 | Univ Iowa Res Found | Device, systems and methods for prediction, screening and monitoring of encephalopathy / delirium |
| CA3082878C (en) | 2017-11-17 | 2024-02-20 | The Research Foundation for State University of New York | A method for treating damaged peripheral nerves using x-ray microbeam irradiation |
| CN110946991A (zh) * | 2018-09-27 | 2020-04-03 | 广州中医药大学(广州中医药研究院) | 神经调节蛋白1的应用 |
| CN114929099B (zh) * | 2019-08-01 | 2025-08-15 | 马克·埃文斯 | 用于在分娩期间和分娩之前降低人类胎儿神经损伤风险及鉴定神经损伤存在的方法和设备 |
| CN116116737B (zh) * | 2023-04-14 | 2023-06-30 | 新华手术器械有限公司 | 止血钳毛坯自动上料装置及使用方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US888A (en) | 1838-08-20 | perkins | ||
| US7037A (en) | 1850-01-22 | Grid-ikon slide-valve | ||
| US5716930A (en) | 1991-04-10 | 1998-02-10 | Ludwig Institute For Cancer Research | Glial growth factors |
| US5530109A (en) | 1991-04-10 | 1996-06-25 | Ludwig Institute For Cancer Research | DNA encoding glial mitogenic factors |
| US6087323A (en) * | 1992-04-03 | 2000-07-11 | Cambridge Neuroscience, Inc. | Use of neuregulins as modulators of cellular communication |
| US7037888B1 (en) | 1992-04-03 | 2006-05-02 | Acorda Therapeutics, Inc. | Methods for treating muscle diseases and disorders |
| EP1028735A4 (en) * | 1997-10-14 | 2003-08-06 | Cenes Pharmaceuticals Inc | THERAPEUTIC METHOD COMPRISING THE USE OF NEUREGULIN |
| CA2409996C (en) * | 2000-05-23 | 2016-03-01 | Cenes Pharmaceuticals, Inc. | Nrg-2 nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods |
| WO2009046453A2 (en) * | 2007-10-05 | 2009-04-09 | New England Medical Center (Nemc) | Use of neuregulin-1 in reducing brain damage |
| CN104645315A (zh) * | 2008-02-29 | 2015-05-27 | 阿索尔达治疗公司 | 达到所需胶质生长因子2血浆水平的方法 |
| DK3338791T3 (da) * | 2008-07-17 | 2019-12-16 | Acorda Therapeutics Inc | Terapeutisk dosering af en neuregulin i behandling eller profylaxis af hjertesvigt |
| KR101237927B1 (ko) * | 2009-05-07 | 2013-03-04 | (주)문엔제이 | 신경손상 및 신경질환 예방 또는 치료용 약학조성물 |
| PL3235504T3 (pl) * | 2009-10-14 | 2020-03-31 | Acorda Therapeutics, Inc. | Zastosowanie neureguliny do leczenia uszkodzenia nerwu obwodowego |
| CA2845198A1 (en) * | 2010-08-13 | 2012-02-16 | Georgetown University | Ggf2 and methods of use |
-
2013
- 2013-03-29 DK DK17187879.6T patent/DK3278811T3/da active
- 2013-03-29 AU AU2013237896A patent/AU2013237896B2/en not_active Ceased
- 2013-03-29 EP EP13716919.9A patent/EP2830645B1/en active Active
- 2013-03-29 JP JP2015503646A patent/JP6420233B2/ja not_active Expired - Fee Related
- 2013-03-29 IL IL288785A patent/IL288785B2/en unknown
- 2013-03-29 PL PL17187879T patent/PL3278811T3/pl unknown
- 2013-03-29 US US14/389,655 patent/US20150094263A1/en not_active Abandoned
- 2013-03-29 ES ES13716919.9T patent/ES2647917T3/es active Active
- 2013-03-29 CN CN201380026579.2A patent/CN104321072A/zh active Pending
- 2013-03-29 CN CN201610027758.3A patent/CN106511971A/zh active Pending
- 2013-03-29 PT PT137169199T patent/PT2830645T/pt unknown
- 2013-03-29 PT PT171878796T patent/PT3278811T/pt unknown
- 2013-03-29 CA CA2869070A patent/CA2869070A1/en active Pending
- 2013-03-29 PL PL13716919T patent/PL2830645T3/pl unknown
- 2013-03-29 WO PCT/US2013/034634 patent/WO2013149163A1/en not_active Ceased
- 2013-03-29 EP EP17187879.6A patent/EP3278811B1/en active Active
- 2013-03-29 ES ES17187879T patent/ES2857810T3/es active Active
- 2013-03-29 NZ NZ700546A patent/NZ700546A/en not_active IP Right Cessation
- 2013-03-29 BR BR112014024308-5A patent/BR112014024308B1/pt not_active IP Right Cessation
- 2013-03-29 DK DK13716919.9T patent/DK2830645T3/da active
- 2013-03-29 EP EP20211026.8A patent/EP3842059A1/en not_active Withdrawn
- 2013-03-29 MX MX2014011838A patent/MX354598B/es active IP Right Grant
-
2014
- 2014-09-29 IL IL234882A patent/IL234882B/en active IP Right Grant
-
2015
- 2015-12-22 US US14/978,287 patent/US20160346353A1/en not_active Abandoned
-
2017
- 2017-04-07 JP JP2017076415A patent/JP2017149746A/ja active Pending
-
2018
- 2018-01-24 AU AU2018200592A patent/AU2018200592A1/en not_active Abandoned
-
2019
- 2019-04-03 JP JP2019070976A patent/JP2019131582A/ja active Pending
- 2019-04-05 AU AU2019202401A patent/AU2019202401B2/en not_active Ceased
-
2020
- 2020-03-09 IL IL273186A patent/IL273186B/en unknown
- 2020-10-30 AU AU2020260539A patent/AU2020260539A1/en not_active Abandoned
-
2021
- 2021-01-15 JP JP2021004728A patent/JP7108724B2/ja active Active
-
2022
- 2022-03-28 US US17/705,840 patent/US20230117985A1/en not_active Abandoned
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