AU2013237896B2 - Use of neuregulin to treat peripheral nerve injury - Google Patents

Use of neuregulin to treat peripheral nerve injury Download PDF

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Publication number
AU2013237896B2
AU2013237896B2 AU2013237896A AU2013237896A AU2013237896B2 AU 2013237896 B2 AU2013237896 B2 AU 2013237896B2 AU 2013237896 A AU2013237896 A AU 2013237896A AU 2013237896 A AU2013237896 A AU 2013237896A AU 2013237896 B2 AU2013237896 B2 AU 2013237896B2
Authority
AU
Australia
Prior art keywords
weeks
neuregulin
injury
nerve
ggf2
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2013237896A
Other languages
English (en)
Other versions
AU2013237896A1 (en
Inventor
Anthony J. Bella
Anthony O. Caggiano
Raymond Warren Colburn
Anindita Ganguly
Jennifer Iaci
Thomas Parry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Acorda Therapeutics Inc
Original Assignee
Acorda Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acorda Therapeutics Inc filed Critical Acorda Therapeutics Inc
Publication of AU2013237896A1 publication Critical patent/AU2013237896A1/en
Application granted granted Critical
Publication of AU2013237896B2 publication Critical patent/AU2013237896B2/en
Priority to AU2018200592A priority Critical patent/AU2018200592A1/en
Priority to AU2019202401A priority patent/AU2019202401B2/en
Priority to AU2020260539A priority patent/AU2020260539A1/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1883Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AU2013237896A 2012-03-30 2013-03-29 Use of neuregulin to treat peripheral nerve injury Ceased AU2013237896B2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2018200592A AU2018200592A1 (en) 2012-03-30 2018-01-24 Use of Neuregulin to Treat Peripheral Nerve Injury
AU2019202401A AU2019202401B2 (en) 2012-03-30 2019-04-05 Use of neuregulin to treat peripheral nerve injury
AU2020260539A AU2020260539A1 (en) 2012-03-30 2020-10-30 Use of neuregulin to treat peripheral nerve injury

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201261618381P 2012-03-30 2012-03-30
US61/618,381 2012-03-30
US201261674060P 2012-07-20 2012-07-20
US61/674,060 2012-07-20
US201261693585P 2012-08-27 2012-08-27
US201261693589P 2012-08-27 2012-08-27
US61/693,589 2012-08-27
US61/693,585 2012-08-27
US201361785419P 2013-03-14 2013-03-14
US61/785,419 2013-03-14
PCT/US2013/034634 WO2013149163A1 (en) 2012-03-30 2013-03-29 Use of neuregulin to treat peripheral nerve injury

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2018200592A Division AU2018200592A1 (en) 2012-03-30 2018-01-24 Use of Neuregulin to Treat Peripheral Nerve Injury

Publications (2)

Publication Number Publication Date
AU2013237896A1 AU2013237896A1 (en) 2014-10-16
AU2013237896B2 true AU2013237896B2 (en) 2017-11-02

Family

ID=48128617

Family Applications (4)

Application Number Title Priority Date Filing Date
AU2013237896A Ceased AU2013237896B2 (en) 2012-03-30 2013-03-29 Use of neuregulin to treat peripheral nerve injury
AU2018200592A Abandoned AU2018200592A1 (en) 2012-03-30 2018-01-24 Use of Neuregulin to Treat Peripheral Nerve Injury
AU2019202401A Ceased AU2019202401B2 (en) 2012-03-30 2019-04-05 Use of neuregulin to treat peripheral nerve injury
AU2020260539A Abandoned AU2020260539A1 (en) 2012-03-30 2020-10-30 Use of neuregulin to treat peripheral nerve injury

Family Applications After (3)

Application Number Title Priority Date Filing Date
AU2018200592A Abandoned AU2018200592A1 (en) 2012-03-30 2018-01-24 Use of Neuregulin to Treat Peripheral Nerve Injury
AU2019202401A Ceased AU2019202401B2 (en) 2012-03-30 2019-04-05 Use of neuregulin to treat peripheral nerve injury
AU2020260539A Abandoned AU2020260539A1 (en) 2012-03-30 2020-10-30 Use of neuregulin to treat peripheral nerve injury

Country Status (15)

Country Link
US (3) US20150094263A1 (enExample)
EP (3) EP2830645B1 (enExample)
JP (4) JP6420233B2 (enExample)
CN (2) CN104321072A (enExample)
AU (4) AU2013237896B2 (enExample)
BR (1) BR112014024308B1 (enExample)
CA (1) CA2869070A1 (enExample)
DK (2) DK3278811T3 (enExample)
ES (2) ES2647917T3 (enExample)
IL (3) IL288785B2 (enExample)
MX (1) MX354598B (enExample)
NZ (1) NZ700546A (enExample)
PL (2) PL3278811T3 (enExample)
PT (2) PT2830645T (enExample)
WO (1) WO2013149163A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3338791T3 (da) 2008-07-17 2019-12-16 Acorda Therapeutics Inc Terapeutisk dosering af en neuregulin i behandling eller profylaxis af hjertesvigt
PL3235504T3 (pl) 2009-10-14 2020-03-31 Acorda Therapeutics, Inc. Zastosowanie neureguliny do leczenia uszkodzenia nerwu obwodowego
ITUB20155471A1 (it) * 2015-11-11 2017-05-11 Univ Degli Studi Di Torino Coniugato della neuregulina 1 per il trattamento delle lesioni dei nervi periferici
IL294038A (en) * 2015-12-04 2022-08-01 Univ Iowa Res Found Device, systems and methods for prediction, screening and monitoring of encephalopathy / delirium
CA3082878C (en) 2017-11-17 2024-02-20 The Research Foundation for State University of New York A method for treating damaged peripheral nerves using x-ray microbeam irradiation
CN110946991A (zh) * 2018-09-27 2020-04-03 广州中医药大学(广州中医药研究院) 神经调节蛋白1的应用
CN114929099B (zh) * 2019-08-01 2025-08-15 马克·埃文斯 用于在分娩期间和分娩之前降低人类胎儿神经损伤风险及鉴定神经损伤存在的方法和设备
CN116116737B (zh) * 2023-04-14 2023-06-30 新华手术器械有限公司 止血钳毛坯自动上料装置及使用方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996015812A1 (en) * 1994-11-17 1996-05-30 Cambridge Neuroscience, Inc. Use of neuregulins as modulators of cellular communication
WO2001089568A1 (en) * 2000-05-23 2001-11-29 Cenes Pharmaceuticals, Inc. Nrg-2 nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
WO2009108390A2 (en) * 2008-02-29 2009-09-03 Acorda Therapeutics, Inc. Method for achieving desired glial growth factor 2 plasma levels
WO2010030317A2 (en) * 2008-07-17 2010-03-18 Acorda Therapeutics, Inc. Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure
US20100286043A1 (en) * 2007-10-05 2010-11-11 Tufts Medical Center, Inc. Use of neuregulin-1 in reducing brain damage
WO2011047183A2 (en) * 2009-10-14 2011-04-21 Acorda Therapeutics, Inc. Use of a neuregulin to treat peripheral nerve injury
WO2012021818A2 (en) * 2010-08-13 2012-02-16 Georgetown University Ggf2 and methods of use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US888A (en) 1838-08-20 perkins
US7037A (en) 1850-01-22 Grid-ikon slide-valve
US5716930A (en) 1991-04-10 1998-02-10 Ludwig Institute For Cancer Research Glial growth factors
US5530109A (en) 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
US7037888B1 (en) 1992-04-03 2006-05-02 Acorda Therapeutics, Inc. Methods for treating muscle diseases and disorders
EP1028735A4 (en) * 1997-10-14 2003-08-06 Cenes Pharmaceuticals Inc THERAPEUTIC METHOD COMPRISING THE USE OF NEUREGULIN
KR101237927B1 (ko) * 2009-05-07 2013-03-04 (주)문엔제이 신경손상 및 신경질환 예방 또는 치료용 약학조성물

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996015812A1 (en) * 1994-11-17 1996-05-30 Cambridge Neuroscience, Inc. Use of neuregulins as modulators of cellular communication
WO2001089568A1 (en) * 2000-05-23 2001-11-29 Cenes Pharmaceuticals, Inc. Nrg-2 nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
US20100286043A1 (en) * 2007-10-05 2010-11-11 Tufts Medical Center, Inc. Use of neuregulin-1 in reducing brain damage
WO2009108390A2 (en) * 2008-02-29 2009-09-03 Acorda Therapeutics, Inc. Method for achieving desired glial growth factor 2 plasma levels
WO2010030317A2 (en) * 2008-07-17 2010-03-18 Acorda Therapeutics, Inc. Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure
WO2011047183A2 (en) * 2009-10-14 2011-04-21 Acorda Therapeutics, Inc. Use of a neuregulin to treat peripheral nerve injury
WO2012021818A2 (en) * 2010-08-13 2012-02-16 Georgetown University Ggf2 and methods of use

Also Published As

Publication number Publication date
JP7108724B2 (ja) 2022-07-28
PT3278811T (pt) 2021-03-03
EP3278811B1 (en) 2020-12-02
EP3842059A1 (en) 2021-06-30
EP2830645B1 (en) 2017-08-30
IL234882B (en) 2020-03-31
ES2647917T3 (es) 2017-12-27
HK1249038A1 (en) 2018-10-26
CN104321072A (zh) 2015-01-28
JP2021059605A (ja) 2021-04-15
DK3278811T3 (da) 2021-03-01
IL273186B (en) 2022-01-01
AU2018200592A1 (en) 2018-02-15
JP6420233B2 (ja) 2018-11-07
CA2869070A1 (en) 2013-10-03
MX354598B (es) 2018-03-12
HK1206632A1 (en) 2016-01-15
PL3278811T3 (pl) 2021-08-02
US20230117985A1 (en) 2023-04-20
IL273186A (en) 2020-04-30
PL2830645T3 (pl) 2018-01-31
BR112014024308A2 (pt) 2017-08-08
IL288785A (en) 2022-02-01
IL234882A0 (en) 2014-12-31
AU2013237896A1 (en) 2014-10-16
AU2019202401A1 (en) 2019-05-02
EP2830645A1 (en) 2015-02-04
JP2019131582A (ja) 2019-08-08
EP3278811A1 (en) 2018-02-07
JP2015514096A (ja) 2015-05-18
AU2019202401B2 (en) 2020-10-15
BR112014024308B1 (pt) 2021-11-30
DK2830645T3 (da) 2017-11-20
CN106511971A (zh) 2017-03-22
BR112014024308A8 (pt) 2018-01-23
US20160346353A1 (en) 2016-12-01
PT2830645T (pt) 2017-11-28
AU2020260539A1 (en) 2020-11-26
MX2014011838A (es) 2015-03-09
WO2013149163A1 (en) 2013-10-03
ES2857810T3 (es) 2021-09-29
US20150094263A1 (en) 2015-04-02
NZ700546A (en) 2017-05-26
JP2017149746A (ja) 2017-08-31
IL288785B (en) 2022-11-01
IL288785B2 (en) 2023-03-01

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired