CA2869070A1 - Use of neuregulin to treat peripheral nerve injury - Google Patents

Use of neuregulin to treat peripheral nerve injury Download PDF

Info

Publication number
CA2869070A1
CA2869070A1 CA2869070A CA2869070A CA2869070A1 CA 2869070 A1 CA2869070 A1 CA 2869070A1 CA 2869070 A CA2869070 A CA 2869070A CA 2869070 A CA2869070 A CA 2869070A CA 2869070 A1 CA2869070 A1 CA 2869070A1
Authority
CA
Canada
Prior art keywords
composition
body weight
neuregulin
weeks
effective amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA2869070A
Other languages
English (en)
French (fr)
Inventor
Anthony O. Caggiano
Anthony J. Bella
Anindita Ganguly
Jennifer Iaci
Thomas Parry
Raymond Warren Colburn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Acorda Therapeutics Inc
Original Assignee
Acorda Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acorda Therapeutics Inc filed Critical Acorda Therapeutics Inc
Publication of CA2869070A1 publication Critical patent/CA2869070A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1883—Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CA2869070A 2012-03-30 2013-03-29 Use of neuregulin to treat peripheral nerve injury Pending CA2869070A1 (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201261618381P 2012-03-30 2012-03-30
US61/618,381 2012-03-30
US201261674060P 2012-07-20 2012-07-20
US61/674,060 2012-07-20
US201261693585P 2012-08-27 2012-08-27
US201261693589P 2012-08-27 2012-08-27
US61/693,589 2012-08-27
US61/693,585 2012-08-27
US201361785419P 2013-03-14 2013-03-14
US61/785,419 2013-03-14
PCT/US2013/034634 WO2013149163A1 (en) 2012-03-30 2013-03-29 Use of neuregulin to treat peripheral nerve injury

Publications (1)

Publication Number Publication Date
CA2869070A1 true CA2869070A1 (en) 2013-10-03

Family

ID=48128617

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2869070A Pending CA2869070A1 (en) 2012-03-30 2013-03-29 Use of neuregulin to treat peripheral nerve injury

Country Status (15)

Country Link
US (3) US20150094263A1 (enExample)
EP (3) EP2830645B1 (enExample)
JP (4) JP6420233B2 (enExample)
CN (2) CN104321072A (enExample)
AU (4) AU2013237896B2 (enExample)
BR (1) BR112014024308B1 (enExample)
CA (1) CA2869070A1 (enExample)
DK (2) DK3278811T3 (enExample)
ES (2) ES2647917T3 (enExample)
IL (3) IL288785B2 (enExample)
MX (1) MX354598B (enExample)
NZ (1) NZ700546A (enExample)
PL (2) PL3278811T3 (enExample)
PT (2) PT2830645T (enExample)
WO (1) WO2013149163A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3338791T3 (da) 2008-07-17 2019-12-16 Acorda Therapeutics Inc Terapeutisk dosering af en neuregulin i behandling eller profylaxis af hjertesvigt
PL3235504T3 (pl) 2009-10-14 2020-03-31 Acorda Therapeutics, Inc. Zastosowanie neureguliny do leczenia uszkodzenia nerwu obwodowego
ITUB20155471A1 (it) * 2015-11-11 2017-05-11 Univ Degli Studi Di Torino Coniugato della neuregulina 1 per il trattamento delle lesioni dei nervi periferici
IL294038A (en) * 2015-12-04 2022-08-01 Univ Iowa Res Found Device, systems and methods for prediction, screening and monitoring of encephalopathy / delirium
CA3082878C (en) 2017-11-17 2024-02-20 The Research Foundation for State University of New York A method for treating damaged peripheral nerves using x-ray microbeam irradiation
CN110946991A (zh) * 2018-09-27 2020-04-03 广州中医药大学(广州中医药研究院) 神经调节蛋白1的应用
CN114929099B (zh) * 2019-08-01 2025-08-15 马克·埃文斯 用于在分娩期间和分娩之前降低人类胎儿神经损伤风险及鉴定神经损伤存在的方法和设备
CN116116737B (zh) * 2023-04-14 2023-06-30 新华手术器械有限公司 止血钳毛坯自动上料装置及使用方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US888A (en) 1838-08-20 perkins
US7037A (en) 1850-01-22 Grid-ikon slide-valve
US5716930A (en) 1991-04-10 1998-02-10 Ludwig Institute For Cancer Research Glial growth factors
US5530109A (en) 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
US6087323A (en) * 1992-04-03 2000-07-11 Cambridge Neuroscience, Inc. Use of neuregulins as modulators of cellular communication
US7037888B1 (en) 1992-04-03 2006-05-02 Acorda Therapeutics, Inc. Methods for treating muscle diseases and disorders
EP1028735A4 (en) * 1997-10-14 2003-08-06 Cenes Pharmaceuticals Inc THERAPEUTIC METHOD COMPRISING THE USE OF NEUREGULIN
CA2409996C (en) * 2000-05-23 2016-03-01 Cenes Pharmaceuticals, Inc. Nrg-2 nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
WO2009046453A2 (en) * 2007-10-05 2009-04-09 New England Medical Center (Nemc) Use of neuregulin-1 in reducing brain damage
CN104645315A (zh) * 2008-02-29 2015-05-27 阿索尔达治疗公司 达到所需胶质生长因子2血浆水平的方法
DK3338791T3 (da) * 2008-07-17 2019-12-16 Acorda Therapeutics Inc Terapeutisk dosering af en neuregulin i behandling eller profylaxis af hjertesvigt
KR101237927B1 (ko) * 2009-05-07 2013-03-04 (주)문엔제이 신경손상 및 신경질환 예방 또는 치료용 약학조성물
PL3235504T3 (pl) * 2009-10-14 2020-03-31 Acorda Therapeutics, Inc. Zastosowanie neureguliny do leczenia uszkodzenia nerwu obwodowego
CA2845198A1 (en) * 2010-08-13 2012-02-16 Georgetown University Ggf2 and methods of use

Also Published As

Publication number Publication date
JP7108724B2 (ja) 2022-07-28
PT3278811T (pt) 2021-03-03
EP3278811B1 (en) 2020-12-02
EP3842059A1 (en) 2021-06-30
EP2830645B1 (en) 2017-08-30
IL234882B (en) 2020-03-31
ES2647917T3 (es) 2017-12-27
HK1249038A1 (en) 2018-10-26
CN104321072A (zh) 2015-01-28
JP2021059605A (ja) 2021-04-15
DK3278811T3 (da) 2021-03-01
IL273186B (en) 2022-01-01
AU2018200592A1 (en) 2018-02-15
JP6420233B2 (ja) 2018-11-07
MX354598B (es) 2018-03-12
HK1206632A1 (en) 2016-01-15
PL3278811T3 (pl) 2021-08-02
US20230117985A1 (en) 2023-04-20
IL273186A (en) 2020-04-30
PL2830645T3 (pl) 2018-01-31
BR112014024308A2 (pt) 2017-08-08
IL288785A (en) 2022-02-01
IL234882A0 (en) 2014-12-31
AU2013237896A1 (en) 2014-10-16
AU2019202401A1 (en) 2019-05-02
EP2830645A1 (en) 2015-02-04
JP2019131582A (ja) 2019-08-08
EP3278811A1 (en) 2018-02-07
JP2015514096A (ja) 2015-05-18
AU2019202401B2 (en) 2020-10-15
AU2013237896B2 (en) 2017-11-02
BR112014024308B1 (pt) 2021-11-30
DK2830645T3 (da) 2017-11-20
CN106511971A (zh) 2017-03-22
BR112014024308A8 (pt) 2018-01-23
US20160346353A1 (en) 2016-12-01
PT2830645T (pt) 2017-11-28
AU2020260539A1 (en) 2020-11-26
MX2014011838A (es) 2015-03-09
WO2013149163A1 (en) 2013-10-03
ES2857810T3 (es) 2021-09-29
US20150094263A1 (en) 2015-04-02
NZ700546A (en) 2017-05-26
JP2017149746A (ja) 2017-08-31
IL288785B (en) 2022-11-01
IL288785B2 (en) 2023-03-01

Similar Documents

Publication Publication Date Title
US20230117985A1 (en) Use of neuregulin to treat peripheral nerve injury
US20180311312A1 (en) Use of a Neuregulin to Treat Peripheral Nerve Injury
HK40055472A (en) Ggf2 to treat surgical peripheral nerve injury or neuropathic pain therefrom
HK1249038B (en) Use of ggf2 to treat neuropathic pain upon peripheral nerve injury
HK1206632B (en) Neuregulin for use in treating peripheral nerve injury
HK40015800A (en) Use of a neuregulin to treat peripheral nerve injury
HK1174548B (en) Use of a neuregulin to treat cavernous nerve injury
HK1245142B (en) Use of a neuregulin to treat peripheral nerve injury
HK1204951B (en) Use of a neuregulin to treat peripheral nerve injury
NZ765776A (en) Use of a neuregulin to treat peripheral nerve injury
NZ763184B2 (en) Use of a neuregulin to treat peripheral nerve injury
NZ765776B2 (en) Use of a neuregulin to treat peripheral nerve injury

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20171004

EEER Examination request

Effective date: 20171004

EEER Examination request

Effective date: 20171004

EEER Examination request

Effective date: 20171004

EEER Examination request

Effective date: 20171004