JP2015514062A5 - - Google Patents

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Publication number
JP2015514062A5
JP2015514062A5 JP2015500673A JP2015500673A JP2015514062A5 JP 2015514062 A5 JP2015514062 A5 JP 2015514062A5 JP 2015500673 A JP2015500673 A JP 2015500673A JP 2015500673 A JP2015500673 A JP 2015500673A JP 2015514062 A5 JP2015514062 A5 JP 2015514062A5
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JP
Japan
Prior art keywords
agent
cadherin
fragment
secad
inhibits
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2015500673A
Other languages
English (en)
Japanese (ja)
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JP2015514062A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/032656 external-priority patent/WO2013138790A1/en
Publication of JP2015514062A publication Critical patent/JP2015514062A/ja
Publication of JP2015514062A5 publication Critical patent/JP2015514062A5/ja
Pending legal-status Critical Current

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JP2015500673A 2012-03-15 2013-03-15 Ｅ−カドヘリンの細胞外ドメインの阻害剤を含む併用療法 Pending JP2015514062A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261611390P 2012-03-15 2012-03-15
US61/611,390 2012-03-15
US201261736475P 2012-12-12 2012-12-12
US61/736,475 2012-12-12
PCT/US2013/032656 WO2013138790A1 (en) 2012-03-15 2013-03-15 Combination therapies including inhibitors of the extracellular domain of e-cadherin

Publications (2)

Publication Number Publication Date
JP2015514062A JP2015514062A (ja) 2015-05-18
JP2015514062A5 true JP2015514062A5 (enExample) 2016-05-12

Family

ID=49161879

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015500673A Pending JP2015514062A (ja) 2012-03-15 2013-03-15 Ｅ−カドヘリンの細胞外ドメインの阻害剤を含む併用療法

Country Status (8)

Country Link
US (2) US20150037354A1 (enExample)
EP (1) EP2844270A4 (enExample)
JP (1) JP2015514062A (enExample)
KR (1) KR20140138956A (enExample)
CN (1) CN104519899A (enExample)
CA (1) CA2867456A1 (enExample)
RU (1) RU2014141114A (enExample)
WO (1) WO2013138790A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9618514B2 (en) 2012-09-17 2017-04-11 Agios Pharmaceuticals, Inc Methods of evaluating patients using E-cadherin and vimentin
KR20150085078A (ko) 2012-11-21 2015-07-22 아지오스 파마슈티컬스 아이엔씨. 글루타마제 억제제 및 사용 방법
WO2014079011A1 (en) 2012-11-22 2014-05-30 Agios Pharmaceuticals, Inc. Heterocyclic compounds for inhibiting glutaminase and their methods of use
KR20160127149A (ko) 2014-03-21 2016-11-02 아지오스 파마슈티컬스 아이엔씨. 화합물 및 이의 사용 방법
WO2016008975A1 (en) * 2014-07-18 2016-01-21 Sanofi Method for predicting the outcome of a treatment with aflibercept of a patient suspected to suffer from a cancer
CN111208283B (zh) * 2018-11-21 2023-09-26 中国科学院分子细胞科学卓越创新中心 增效的肿瘤抑制组合物及其应用
CN115040695B (zh) * 2021-03-09 2023-10-13 南开大学 一种基于VE-cad-Fc/N-cad-Fc的融合蛋白活性界面的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT414097B (de) * 2004-06-25 2006-09-15 Petzelbauer Peter Dr Pharmazeutische zubereitung zur behandlung von schock
US8455249B2 (en) * 2009-05-01 2013-06-04 The University Of Tokyo Highly effective anti-cadherin antibody for induction of antibody-dependent cellular cytotoxicity in vivo
KR20140075639A (ko) * 2010-10-27 2014-06-19 더 리서치 파운데이션 포 더 스테이트 유니버시티 오브 뉴욕 암 치료법을 위한 e-카드헤린의 가용성 세포외 도메인의 표적화 조성물 및 관련 방법

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