JP2015513403A5 - - Google Patents

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JP2015513403A5
JP2015513403A5 JP2014560106A JP2014560106A JP2015513403A5 JP 2015513403 A5 JP2015513403 A5 JP 2015513403A5 JP 2014560106 A JP2014560106 A JP 2014560106A JP 2014560106 A JP2014560106 A JP 2014560106A JP 2015513403 A5 JP2015513403 A5 JP 2015513403A5
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Japan
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treg
donor
cells
reactive
sbc
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JP2014560106A
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Japanese (ja)
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JP2015513403A (ja
JP6422344B2 (ja
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Priority claimed from PCT/US2013/028734 external-priority patent/WO2013131045A1/en
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Publication of JP2015513403A5 publication Critical patent/JP2015513403A5/ja
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JP2014560106A 2012-03-02 2013-03-01 同種抗原反応性の制御性ｔ細胞を増大させる方法 Expired - Fee Related JP6422344B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261606329P 2012-03-02 2012-03-02
US61/606,329 2012-03-02
PCT/US2013/028734 WO2013131045A1 (en) 2012-03-02 2013-03-01 Expansion of alloantigen-reactive regulatory t cells

Publications (3)

Publication Number Publication Date
JP2015513403A JP2015513403A (ja) 2015-05-14
JP2015513403A5 true JP2015513403A5 (enExample) 2017-08-10
JP6422344B2 JP6422344B2 (ja) 2018-11-14

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JP2014560106A Expired - Fee Related JP6422344B2 (ja) 2012-03-02 2013-03-01 同種抗原反応性の制御性ｔ細胞を増大させる方法

Country Status (8)

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US (2) US9801911B2 (enExample)
EP (2) EP2820125B1 (enExample)
JP (1) JP6422344B2 (enExample)
CN (1) CN104245923B (enExample)
AU (2) AU2013225721B2 (enExample)
CA (1) CA2866116C (enExample)
ES (1) ES2675317T3 (enExample)
WO (1) WO2013131045A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101697473B1 (ko) 2014-11-26 2017-01-18 주식회사 녹십자랩셀 T 세포를 이용한 자연살해세포의 배양방법
CN108463547A (zh) * 2015-10-28 2018-08-28 生命技术股份公司 通过改变细胞表面信号和信号比选择性扩增不同的t细胞亚群
CN105420190B (zh) * 2016-01-08 2018-07-31 无锡药明生基医药科技有限公司 B27添加剂及其类似物在利用无血清培养基培养淋巴细胞中的应用
EP3216861A1 (en) * 2016-03-11 2017-09-13 Fropharm GmbH Immunoregulatory cells and methods for their production
EP3633029A4 (en) 2017-05-26 2021-06-09 Green Cross Lab Cell Corporation METHOD OF DEVELOPING A NATURAL KILLER CELL USING A T-CELL
US20200179449A1 (en) * 2017-06-12 2020-06-11 The Trustees Of Columbia University In The City Of New York Methods for generating polyclonal regulatory t cells
TWI793151B (zh) 2017-08-23 2023-02-21 瑞士商諾華公司 3-(1-氧異吲哚啉-2-基)之氫吡啶-2,6-二酮衍生物及其用途
KR102232321B1 (ko) * 2018-03-23 2021-03-26 주식회사 녹십자랩셀 자연살해세포의 제조방법
BR122022012697B1 (pt) 2018-07-10 2023-04-04 Novartis Ag Usos de derivados de 3-(5-hidróxi-1-oxoisoindolin-2-il)piperidina-2,6- diona, e kit
AR116109A1 (es) 2018-07-10 2021-03-31 Novartis Ag Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
JP7179986B2 (ja) 2018-11-14 2022-11-29 グリーン クロス ラボ セル コーポレーション 形質転換されたｔ細胞を用いた臍帯血由来のナチュラルキラー細胞の培養方法
EP3963053A4 (en) * 2019-04-30 2023-01-18 The Regents of the University of California PEARL-FREE EX-VIVO EXPANSION OF HUMAN REGULATORY T-CELLS
CN110195041B (zh) * 2019-06-20 2023-04-25 威海正生生物科技有限公司 利用ASC三维培养体系获得高活性Tregs细胞的方法
WO2021007396A2 (en) 2019-07-09 2021-01-14 The Children's Mercy Hospital Engineered regulatory t cells
PL238336B1 (pl) 2019-08-22 2021-08-09 Gdanski Univ Medyczny Sposób otrzymywania in vitro antygenowo-specyficznych limfocytów T regulatorowych
CA3206049A1 (en) * 2021-02-23 2022-09-01 John Cho Methods for expanding regulatory t cells
WO2025081193A1 (en) * 2023-10-13 2025-04-17 Northwestern University Antigen specific expansion of regulatory t cells
JP7627920B1 (ja) 2023-12-11 2025-02-07 浩 宮内 移植材料の評価方法

Family Cites Families (15)

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US5540926A (en) 1992-09-04 1996-07-30 Bristol-Myers Squibb Company Soluble and its use in B cell stimulation
US7572631B2 (en) 2000-02-24 2009-08-11 Invitrogen Corporation Activation and expansion of T cells
US7541184B2 (en) 2000-02-24 2009-06-02 Invitrogen Corporation Activation and expansion of cells
ATE460475T1 (de) 2000-04-11 2010-03-15 Univ Southern California Methode zur verhinderung der transplantatabstossung unter verwendung von tgf- beta zur induktion von t-suppressorzellen
US6746670B2 (en) 2000-08-15 2004-06-08 Schering Corporation Regulatory T cells; methods
US6670146B2 (en) 2000-10-04 2003-12-30 Schering Corporation Regulatory T cells; methods
US7745140B2 (en) 2002-01-03 2010-06-29 The Trustees Of The University Of Pennsylvania Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool
US7494812B2 (en) 2003-04-01 2009-02-24 University Of Southern California Generation of human regulatory T cells by bacterial toxins for the treatment of inflammatory disorders
US7651855B2 (en) 2003-04-17 2010-01-26 The Trustees Of The University Of Pennsylvania Regulatory T cells and their use in immunotherapy and suppression of autoimmune responses
FR2856700B1 (fr) 2003-06-24 2007-06-08 Txcell Procede d'identification de lymphocytes tr1 regulateurs par la presence et la surexpression de molecules specifiques et ses applications
JP2007538000A (ja) 2004-01-08 2007-12-27 リージエンツ・オブ・ザ・ユニバーシテイ・オブ・カリフオルニア 制御性ｔ細胞は自己免疫を抑制する
ES2686593T3 (es) * 2006-05-31 2018-10-18 The Regents Of The University Of California Expresión de CD127 que correlaciona inversamente con FoxP3 y la función supresora de Treg CD4+
EP2225365A1 (en) * 2007-11-30 2010-09-08 Therakos, Inc. Process for reducing effects of graft versus host disease using ex vivo expanded cd4+cd25+ regulatory t cells
US8658159B2 (en) 2008-06-30 2014-02-25 Versitech Limited Method to induce and expand therapeutic alloantigen-specific human regulatory T cells in large-scale
WO2010129770A1 (en) 2009-05-07 2010-11-11 The University Of Utah Research Foundation Methods for expanding human t regulatory cells and uses of same

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