JP2015512246A5 - - Google Patents

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Publication number
JP2015512246A5
JP2015512246A5 JP2015500675A JP2015500675A JP2015512246A5 JP 2015512246 A5 JP2015512246 A5 JP 2015512246A5 JP 2015500675 A JP2015500675 A JP 2015500675A JP 2015500675 A JP2015500675 A JP 2015500675A JP 2015512246 A5 JP2015512246 A5 JP 2015512246A5
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JP
Japan
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item
domain
polypeptide
protein
items
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JP2015500675A
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English (en)
Japanese (ja)
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JP2015512246A (ja
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Priority claimed from PCT/US2013/032686 external-priority patent/WO2013138795A1/en
Publication of JP2015512246A publication Critical patent/JP2015512246A/ja
Publication of JP2015512246A5 publication Critical patent/JP2015512246A5/ja
Pending legal-status Critical Current

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JP2015500675A 2012-03-15 2013-03-15 細胞内抗体および抗体様モイエティの送達のための細胞透過組成物ならびに使用方法 Pending JP2015512246A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261611493P 2012-03-15 2012-03-15
US61/611,493 2012-03-15
PCT/US2013/032686 WO2013138795A1 (en) 2012-03-15 2013-03-15 Cell penetrating compositions for delivery of intracellular antibodies and antibody-like moieties and methods of use

Publications (2)

Publication Number Publication Date
JP2015512246A JP2015512246A (ja) 2015-04-27
JP2015512246A5 true JP2015512246A5 (enExample) 2016-05-12

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ID=49161881

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015500675A Pending JP2015512246A (ja) 2012-03-15 2013-03-15 細胞内抗体および抗体様モイエティの送達のための細胞透過組成物ならびに使用方法

Country Status (6)

Country Link
US (1) US20150266939A1 (enExample)
EP (1) EP2825561A4 (enExample)
JP (1) JP2015512246A (enExample)
AU (1) AU2013231851A1 (enExample)
CA (1) CA2867188A1 (enExample)
WO (1) WO2013138795A1 (enExample)

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EP2928915A4 (en) * 2012-12-07 2016-07-27 Permeon Biolog Inc FGF-10 COMPLEX
WO2015069587A2 (en) 2013-11-06 2015-05-14 Merck Sharp & Dohme Corp. Peptide containing conjugates for dual molecular delivery of oligonucleotides
CN113105559A (zh) * 2013-12-12 2021-07-13 生命技术公司 增强转染的膜穿透性肽和组合物以及其使用方法
EP3094348B1 (en) 2014-01-14 2025-03-05 AbVacc, Inc. Targeting immunological functions to the site of bacterial infections using cell wall targeting domains of bacteriolysins
WO2015121457A1 (en) 2014-02-13 2015-08-20 Westphal Sören Fgf-8 for use in treating diseases or disorders of energy homeostasis
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
MX2017006167A (es) 2014-11-12 2018-03-23 Siamab Therapeutics Inc Compuestos que interactúan con glicanos y métodos de uso.
US10507228B2 (en) * 2015-04-20 2019-12-17 H. Lee Moffitt Cancer Center And Research Institute, Inc. Methods and compositions related to KRAS inhibitors
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US9957325B2 (en) * 2015-10-13 2018-05-01 Formurex, Inc. Synthetic antibody mimic peptides
CA3002097A1 (en) 2015-11-12 2017-05-18 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
WO2017120213A1 (en) * 2016-01-05 2017-07-13 Colorado State University Research Foundation Compositions comprising resurfaced cell-penetrating nanobodies and methods of use thereof
WO2017132235A1 (en) * 2016-01-26 2017-08-03 Dana-Farber Cancer Institute, Inc. METHODS FOR TREATING BRAIN METASTASES USING COMBINATIONS OF ANTI-P13K AND ANTI-mTOR AGENTS
CN105837665B (zh) * 2016-05-16 2019-04-30 江苏大学 特异性抑制hb-egf促肿瘤细胞迁移浸润的多肽
US9611297B1 (en) 2016-08-26 2017-04-04 Thrasos Therapeutics Inc. Compositions and methods for the treatment of cast nephropathy and related conditions
WO2018053463A1 (en) 2016-09-19 2018-03-22 H. Lee Moffitt Cancer Center And Research Institute, Inc. Artificial antigen presenting cells for genetic engineering of immune cells
WO2018094143A1 (en) 2016-11-17 2018-05-24 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
AU2017375828B2 (en) * 2016-12-16 2021-04-15 Avixgen Inc Cytoplasmic transduction peptide and intracellular messenger comprising same
WO2018111051A1 (ko) * 2016-12-16 2018-06-21 (주)에빅스젠 세포막 투과 펩티드 및 이를 포함하는 세포내 전달체
US12077590B2 (en) 2017-02-22 2024-09-03 H. Lee Moffitt Cancer Center And Research Institute, Inc. Bispecific antibody for cancer immunotherapy
KR20240044544A (ko) 2017-03-03 2024-04-04 씨젠 인크. 글리칸-상호작용 화합물 및 사용 방법
KR101933217B1 (ko) 2017-12-28 2018-12-27 (주) 에빅스젠 피부 염증 억제용 펩티드 및 이를 포함하는 피부 염증 예방 또는 치료용 조성물
EP3790571B1 (en) * 2018-05-03 2024-08-14 University Of Utah Research Foundation Peptides derived from oca-b for use in the treatment of autoimmune diseases and of leukemia
CN112912103B (zh) * 2018-05-21 2025-08-29 广州邦定生物技术有限公司 多价蛋白质复合物
EP3808840A4 (en) * 2018-06-14 2022-03-23 Avixgen Inc. Pharmaceutical composition comprising fusion protein of cell-penetrating peptide and rpe65 for treatment of leber's congenital amaurosis
JP7113918B2 (ja) * 2018-06-14 2022-08-05 アヴィックスジェン・インコーポレイテッド 細胞透過ペプチドと結合した融合タンパク質、および融合タンパク質または細胞透過ペプチドと上皮細胞成長因子を有効成分として含む組成物
GB201815045D0 (en) 2018-09-14 2018-10-31 Univ Ulster Bispecific antibody targeting IL-1R1 and NLPR3
US12643944B2 (en) 2019-11-12 2026-06-02 Iprogen Biotech Inc. Antibody-payload conjugates with enhanced delivery domain and uses thereof
EP4101866A4 (en) 2020-02-06 2024-04-24 Ajou University Industry-Academic Cooperation Foundation FUSION ANTIBODIES FOR PRESENTING AN ANTIGEN-DERIVED T-CELL ANTIGEN EPITOPE OR A PEPTIDE CONTAINING THE SAME ON THE CELL SURFACE AND COMPOSITION THEREOF
CN116234902A (zh) * 2020-05-04 2023-06-06 利兰·斯坦福青年大学托管委员会 用于激活和沉默基因表达的效应物结构域的生成、鉴定和表征的组合物、系统和方法
EP4185603A4 (en) * 2020-07-13 2025-04-09 National University of Singapore PEPTIDE ADDUCANT FOR ITS THERAPEUTIC APPLICATIONS IN THE DEVELOPMENT OF VIRAL AND TUMOR VACCINES AND CANCER IMMUNOTHERAPY AS WELL AS AUTOIMMUNE DISEASE DIAGNOSIS AND TREATMENTS
WO2023034993A1 (en) * 2021-09-03 2023-03-09 Gleich Gerald J Compositions and methods for diagnosing, detecting and treating eosinophil-related diseases
CN117736338A (zh) * 2023-12-08 2024-03-22 温州医科大学 一种角质细胞生长因子-透皮肽融合蛋白及其制备与应用
EP4711380A1 (en) * 2024-09-16 2026-03-18 Fundació Institut Hospital del Mar d'Investigacions Mèdiques Ligand-dependent corepressor, (lcor), mutants and fragments thereof, and uses for cancer therapy
WO2026087627A1 (en) * 2024-10-22 2026-04-30 Ospedale San Raffaele S.R.L. Fusion protein
KR102996327B1 (ko) 2025-11-03 2026-07-28 주식회사 코씨드바이오팜 베타 디펜신2 유래 세포 투과능을 개선한 개량형 신규 거대분자 전송 도메인 개발 및 이를 이용한 피부 생리 활성 분자의 경피 전달 시스템

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AU5440800A (en) * 1999-05-21 2000-12-12 Human Genome Sciences, Inc. Fibroblast growth factor 10
EE200200531A (et) * 2002-09-17 2004-04-15 O� InBio Terapeutiliste rakkusisenevate antikehade saamineja kasutamine
AU2010238346A1 (en) * 2009-04-14 2011-11-03 Trojan Technologies Ltd. Therapeutic Antennapedia-antibody molecules and methods of use thereof
WO2010129023A2 (en) * 2009-04-28 2010-11-11 President And Fellows Of Harvard College Supercharged proteins for cell penetration
EP2928915A4 (en) * 2012-12-07 2016-07-27 Permeon Biolog Inc FGF-10 COMPLEX

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