JP2015506371A5 - - Google Patents

Download PDF

Info

Publication number
JP2015506371A5
JP2015506371A5 JP2014554804A JP2014554804A JP2015506371A5 JP 2015506371 A5 JP2015506371 A5 JP 2015506371A5 JP 2014554804 A JP2014554804 A JP 2014554804A JP 2014554804 A JP2014554804 A JP 2014554804A JP 2015506371 A5 JP2015506371 A5 JP 2015506371A5
Authority
JP
Japan
Prior art keywords
group
aryl
alkyl
heteroaryl
cycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014554804A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015506371A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/022797 external-priority patent/WO2013112622A1/en
Publication of JP2015506371A publication Critical patent/JP2015506371A/ja
Publication of JP2015506371A5 publication Critical patent/JP2015506371A5/ja
Pending legal-status Critical Current

Links

JP2014554804A 2012-01-25 2013-01-23 (1r,4r)7−オキソ−2−アザビシクロ[2.2.2]オクタ−5−エンおよびその誘導体 Pending JP2015506371A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261741798P 2012-01-25 2012-01-25
US61/741,798 2012-01-25
PCT/US2013/022797 WO2013112622A1 (en) 2012-01-25 2013-01-23 (1r,4r) 7-oxo-2-azabicyclo[2.2.2]oct-5-ene and derivatives thereof

Publications (2)

Publication Number Publication Date
JP2015506371A JP2015506371A (ja) 2015-03-02
JP2015506371A5 true JP2015506371A5 (https=) 2016-03-17

Family

ID=48873876

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014554804A Pending JP2015506371A (ja) 2012-01-25 2013-01-23 (1r,4r)7−オキソ−2−アザビシクロ[2.2.2]オクタ−5−エンおよびその誘導体

Country Status (11)

Country Link
US (2) US20130267710A1 (https=)
EP (1) EP2807158A4 (https=)
JP (1) JP2015506371A (https=)
KR (1) KR20140117380A (https=)
CN (2) CN104169279A (https=)
AU (1) AU2013212209A1 (https=)
CA (1) CA2857969A1 (https=)
HK (1) HK1204615A1 (https=)
IL (1) IL233055A (https=)
RU (1) RU2014124531A (https=)
WO (1) WO2013112622A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2942638C (en) 2013-03-15 2026-03-10 Demerx, Inc. Method for noribogaine treatment of addiction in patients on methadone
US9561232B2 (en) 2014-02-18 2017-02-07 Demerx, Inc. Low dose noribogaine for treating nicotine addiction and preventing relapse of nicotine use
US9591978B2 (en) 2014-03-13 2017-03-14 Demerx, Inc. Methods and compositions for pre-screening patients for treatment with noribogaine
CA2989550C (en) * 2014-06-18 2023-08-08 Demerx, Inc. Halogenated indole and benzofuran derivatives of isoquinuclidene and processes for preparing them
US9549935B2 (en) 2014-07-14 2017-01-24 Demerx, Inc. Methods and compositions for treating migraines using noribogaine
AU2015353414B2 (en) 2014-11-26 2021-04-29 Demerx, Inc. Methods and compositions for potentiating the action of opioid analgesics using iboga alkaloids

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646289A (en) * 1994-10-24 1997-07-08 Eli Lilly And Company Heterocyclic compounds and their preparation and use
FR2884516B1 (fr) * 2005-04-15 2007-06-22 Cerep Sa Antagonistes npy, preparation et utilisations
JP2010229097A (ja) * 2009-03-27 2010-10-14 Tohoku Univ 新規オキサゾリジン誘導体及び新規オキサゾリジン誘導体塩、並びに該オキサゾリジン誘導体塩を不斉有機分子触媒とした光学活性化合物の製造方法
JP5622019B2 (ja) * 2009-09-25 2014-11-12 国立大学法人東北大学 アミノアルコール誘導体塩構造を有する不斉有機分子触媒及び該不斉有機分子触媒を用いた光学活性化合物の製造方法
WO2013028999A1 (en) * 2011-08-24 2013-02-28 The Trustees Of Columbia University In The City Of New York Small molecule inducers of gdnf as potential new therapeutics for neuropsychiatric disorders

Similar Documents

Publication Publication Date Title
JP2015506371A5 (https=)
JP2013507448A5 (https=)
JP2008525416A5 (https=)
JP2009143956A5 (https=)
JP2017119663A5 (https=)
JP2012515776A5 (https=)
RU2018111201A (ru) Фунгицидная композиция для применения в сельском хозяйстве и садоводстве
JP2014500870A5 (https=)
JP2010535722A5 (https=)
MX360667B (es) Derivados de etinilo como moduladores alostericos del receptor de glutamato metabotropico del subtipo 5 (mglur5).
JP2012092103A5 (https=)
AR113903A2 (es) Derivados fungicidas de pirazol carboxamidas
MX353957B (es) Carboxamidas heterociclicas fungicidas.
JP2016510323A5 (https=)
JP2013543842A5 (https=)
JP2017511321A5 (https=)
JP2014526533A5 (https=)
JP2015530408A5 (https=)
JP2018507273A5 (https=)
ZA201002139B (en) New compounds as adenosine a1 receptor antagonists
JP2016529319A5 (https=)
JP2016513122A5 (https=)
WO2009118473A3 (fr) Composés dérivés d'azétidines, leur préparation et leur application en thérapeutique
JP2012509265A5 (https=)
RU2019131147A (ru) Новые хиназолиноновые производные, ингибирующие pi3k, и содержащая их фармацевтическая композиция