JP2015505555A5 - - Google Patents

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Publication number
JP2015505555A5
JP2015505555A5 JP2014555310A JP2014555310A JP2015505555A5 JP 2015505555 A5 JP2015505555 A5 JP 2015505555A5 JP 2014555310 A JP2014555310 A JP 2014555310A JP 2014555310 A JP2014555310 A JP 2014555310A JP 2015505555 A5 JP2015505555 A5 JP 2015505555A5
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JP
Japan
Prior art keywords
inhibition
cancer
compound
protein kinase
autoimmune disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014555310A
Other languages
English (en)
Japanese (ja)
Other versions
JP6199316B2 (ja
JP2015505555A (ja
Filing date
Publication date
Priority claimed from GBGB1201566.5A external-priority patent/GB201201566D0/en
Application filed filed Critical
Publication of JP2015505555A publication Critical patent/JP2015505555A/ja
Publication of JP2015505555A5 publication Critical patent/JP2015505555A5/ja
Application granted granted Critical
Publication of JP6199316B2 publication Critical patent/JP6199316B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2014555310A 2012-01-30 2013-01-30 1H−ピロロ[2,3−b]ピリジン誘導体およびキナーゼ阻害剤としてのその使用 Expired - Fee Related JP6199316B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1201566.5 2012-01-30
GBGB1201566.5A GB201201566D0 (en) 2012-01-30 2012-01-30 New chemical compounds
PCT/GB2013/050212 WO2013114113A1 (en) 2012-01-30 2013-01-30 1h-pyrrolo[2,3-b] pyridine derivatives and their use as kinase inhibitors

Publications (3)

Publication Number Publication Date
JP2015505555A JP2015505555A (ja) 2015-02-23
JP2015505555A5 true JP2015505555A5 (enExample) 2015-11-12
JP6199316B2 JP6199316B2 (ja) 2017-09-20

Family

ID=45876325

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014555310A Expired - Fee Related JP6199316B2 (ja) 2012-01-30 2013-01-30 1H−ピロロ[2,3−b]ピリジン誘導体およびキナーゼ阻害剤としてのその使用

Country Status (21)

Country Link
US (3) US10000481B2 (enExample)
EP (1) EP2809670B1 (enExample)
JP (1) JP6199316B2 (enExample)
CN (4) CN107011341A (enExample)
AU (1) AU2013213954B2 (enExample)
BR (1) BR112014018795B1 (enExample)
CA (1) CA2862940C (enExample)
DK (1) DK2809670T3 (enExample)
EA (1) EA026657B1 (enExample)
ES (1) ES2637340T3 (enExample)
GB (1) GB201201566D0 (enExample)
HK (1) HK1200447A1 (enExample)
HU (1) HUE035332T2 (enExample)
IL (1) IL233595B (enExample)
IN (1) IN2014DN06104A (enExample)
MX (1) MX352927B (enExample)
NZ (1) NZ627361A (enExample)
PL (1) PL2809670T3 (enExample)
PT (1) PT2809670T (enExample)
WO (1) WO2013114113A1 (enExample)
ZA (1) ZA201405070B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201201566D0 (en) 2012-01-30 2012-03-14 Vernalis R&D Ltd New chemical compounds
AR090789A1 (es) * 2012-04-23 2014-12-10 Genentech Inc Intermediarios y procesos para la preparacion de compuestos
US10329288B2 (en) 2013-08-22 2019-06-25 Genentech, Inc. Process for preparing a compound
CN104829609B (zh) * 2014-02-11 2016-08-03 北大方正集团有限公司 取代的吡啶并嘧啶化合物及其制备方法和应用
MA41559A (fr) * 2015-09-08 2017-12-26 Taiho Pharmaceutical Co Ltd Composé de pyrimidine condensé ou un sel de celui-ci
US10032914B2 (en) * 2015-10-20 2018-07-24 Taiwan Semiconductor Manufacturing Co., Ltd. Semiconductor device and manufacturing method thereof
EP3269370B1 (en) 2016-02-23 2020-01-08 Taiho Pharmaceutical Co., Ltd. Novel condensed pyrimidine compound or salt thereof
MY201941A (en) 2017-08-21 2024-03-25 Taiho Pharmaceutical Co Ltd Fusion protein of dctn1 protein with ret protein
WO2020150417A2 (en) 2019-01-17 2020-07-23 Ifm Due, Inc. Compounds and compositions for treating conditions associated with sting activity
CN111518096B (zh) 2019-02-02 2022-02-11 江苏威凯尔医药科技有限公司 两面神激酶jak家族抑制剂及其制备和应用
KR20220042159A (ko) 2019-08-01 2022-04-04 인테그랄 바이오사이언스 피브이티. 엘티디. 키나제 억제제로서의 헤테로사이클릭 화합물 및 이의 용도
IT202000005527A1 (it) * 2020-03-16 2021-09-16 Univ Degli Studi Di Trento Trattamento terapeutico di cromatinopatie
JP2023540674A (ja) * 2020-07-15 2023-09-26 アイエフエム デュー インコーポレイテッド Sting活性に関連する状態を治療するための化合物および組成物
US20230271941A1 (en) 2020-07-15 2023-08-31 Ifm Due, Inc. Compounds and compositions for treating conditions associated with sting activity
TW202216685A (zh) * 2020-07-15 2022-05-01 美商Ifm Due有限公司 用於治療與sting活性相關的病狀之化合物及組合物
CN117529475A (zh) 2021-01-08 2024-02-06 艾福姆德尤股份有限公司 用于治疗与sting活性有关的疾病的含脲或类似物的杂双环化合物及其化合物
JP2025503675A (ja) * 2022-01-12 2025-02-04 アイエフエム デュー インコーポレイテッド Sting活性に関連する病態を治療するための化合物及び組成物
CN116554170A (zh) * 2023-04-26 2023-08-08 上海大学 4-氟-7-氮杂吲哚的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1012976A (en) * 1909-03-25 1911-12-26 Adolf Bordt Adding-machine.
WO2003028724A1 (en) * 2001-10-04 2003-04-10 Smithkline Beecham Corporation Chk1 kinase inhibitors
US7531553B2 (en) * 2003-03-21 2009-05-12 Amgen Inc. Heterocyclic compounds and methods of use
BRPI0416852A (pt) * 2003-11-21 2007-02-27 Array Biopharma Inc inibidores da quinase akt
JP5608097B2 (ja) * 2008-01-08 2014-10-15 アレイ バイオファーマ、インコーポレイテッド キナーゼ阻害薬としてのピロロピリジン
US8916591B2 (en) * 2008-01-22 2014-12-23 Vernalis (R&D) Ltd Indolyl-pyridone derivatives having checkpoint kinase 1 inhibitory activity
CL2009001152A1 (es) * 2008-05-13 2009-10-16 Array Biopharma Inc Compuestos derivados de n-(4-(cicloalquilo nitrogenado-1-il)-1h-pirrolo[2,3-b]piridin-3-il)amida, inhibidores de cinasa; proceso de preparacion; composicion farmaceutica; y su uso para el tratamiento de una enfermedad proliferativa.
KR101764556B1 (ko) 2008-06-11 2017-08-02 제넨테크, 인크. 디아자카르바졸 및 사용 방법
CN102573994B (zh) * 2009-08-06 2015-06-24 默克专利有限公司 双环脲化合物
WO2011146313A1 (en) * 2010-05-19 2011-11-24 The University Of North Carolina At Chapel Hill Pyrazolopyrimidine compounds for the treatment of cancer
GB201201566D0 (en) 2012-01-30 2012-03-14 Vernalis R&D Ltd New chemical compounds

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