JP2015505555A5 - - Google Patents

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Publication number
JP2015505555A5
JP2015505555A5 JP2014555310A JP2014555310A JP2015505555A5 JP 2015505555 A5 JP2015505555 A5 JP 2015505555A5 JP 2014555310 A JP2014555310 A JP 2014555310A JP 2014555310 A JP2014555310 A JP 2014555310A JP 2015505555 A5 JP2015505555 A5 JP 2015505555A5
Authority
JP
Japan
Prior art keywords
inhibition
cancer
compound
protein kinase
autoimmune disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014555310A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015505555A (ja
JP6199316B2 (ja
Filing date
Publication date
Priority claimed from GBGB1201566.5A external-priority patent/GB201201566D0/en
Application filed filed Critical
Publication of JP2015505555A publication Critical patent/JP2015505555A/ja
Publication of JP2015505555A5 publication Critical patent/JP2015505555A5/ja
Application granted granted Critical
Publication of JP6199316B2 publication Critical patent/JP6199316B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2014555310A 2012-01-30 2013-01-30 1H−ピロロ[2,3−b]ピリジン誘導体およびキナーゼ阻害剤としてのその使用 Expired - Fee Related JP6199316B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1201566.5A GB201201566D0 (en) 2012-01-30 2012-01-30 New chemical compounds
GB1201566.5 2012-01-30
PCT/GB2013/050212 WO2013114113A1 (en) 2012-01-30 2013-01-30 1h-pyrrolo[2,3-b] pyridine derivatives and their use as kinase inhibitors

Publications (3)

Publication Number Publication Date
JP2015505555A JP2015505555A (ja) 2015-02-23
JP2015505555A5 true JP2015505555A5 (enExample) 2015-11-12
JP6199316B2 JP6199316B2 (ja) 2017-09-20

Family

ID=45876325

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014555310A Expired - Fee Related JP6199316B2 (ja) 2012-01-30 2013-01-30 1H−ピロロ[2,3−b]ピリジン誘導体およびキナーゼ阻害剤としてのその使用

Country Status (21)

Country Link
US (3) US10000481B2 (enExample)
EP (1) EP2809670B1 (enExample)
JP (1) JP6199316B2 (enExample)
CN (4) CN107011341A (enExample)
AU (1) AU2013213954B2 (enExample)
BR (1) BR112014018795B1 (enExample)
CA (1) CA2862940C (enExample)
DK (1) DK2809670T3 (enExample)
EA (1) EA026657B1 (enExample)
ES (1) ES2637340T3 (enExample)
GB (1) GB201201566D0 (enExample)
HK (1) HK1200447A1 (enExample)
HU (1) HUE035332T2 (enExample)
IL (1) IL233595B (enExample)
IN (1) IN2014DN06104A (enExample)
MX (1) MX352927B (enExample)
NZ (1) NZ627361A (enExample)
PL (1) PL2809670T3 (enExample)
PT (1) PT2809670T (enExample)
WO (1) WO2013114113A1 (enExample)
ZA (1) ZA201405070B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201201566D0 (en) * 2012-01-30 2012-03-14 Vernalis R&D Ltd New chemical compounds
AU2013252514B2 (en) * 2012-04-23 2017-07-20 Genentech, Inc. Intermediates and processes for preparing compounds
KR102325163B1 (ko) * 2013-08-22 2021-11-11 제넨테크, 인크. 화합물의 제조 방법
CN104829609B (zh) * 2014-02-11 2016-08-03 北大方正集团有限公司 取代的吡啶并嘧啶化合物及其制备方法和应用
MA41559A (fr) * 2015-09-08 2017-12-26 Taiho Pharmaceutical Co Ltd Composé de pyrimidine condensé ou un sel de celui-ci
US10032914B2 (en) * 2015-10-20 2018-07-24 Taiwan Semiconductor Manufacturing Co., Ltd. Semiconductor device and manufacturing method thereof
IL261107B2 (en) 2016-02-23 2023-11-01 Taiho Pharmaceutical Co Ltd A novel compressed pyrimidine compound or a salt thereof
SG11202001212SA (en) 2017-08-21 2020-03-30 Taiho Pharmaceutical Co Ltd Fusion protein of dctn1 protein with ret protein
WO2020150417A2 (en) 2019-01-17 2020-07-23 Ifm Due, Inc. Compounds and compositions for treating conditions associated with sting activity
CN111518096B (zh) 2019-02-02 2022-02-11 江苏威凯尔医药科技有限公司 两面神激酶jak家族抑制剂及其制备和应用
CN114728949B (zh) 2019-08-01 2024-11-12 曙方医药 作为激酶抑制剂的杂环化合物及其用途
IT202000005527A1 (it) * 2020-03-16 2021-09-16 Univ Degli Studi Di Trento Trattamento terapeutico di cromatinopatie
EP4182310A1 (en) 2020-07-15 2023-05-24 IFM Due, Inc. Compounds and compositions for treating conditions associated with sting activity
US20230365553A1 (en) * 2020-07-15 2023-11-16 Ifm Due, Inc. Compounds and compositions for treating conditions associated with sting activity
TW202216685A (zh) * 2020-07-15 2022-05-01 美商Ifm Due有限公司 用於治療與sting活性相關的病狀之化合物及組合物
WO2022150585A1 (en) 2021-01-08 2022-07-14 Ifm Due, Inc. Heterobicyclic compounds having an urea or analogue and their compositions for treating conditions associated with sting activity
PY2269135A (es) 2021-08-10 2024-01-29 Ifm Due Inc Compuestos y composiciones para tratar afecciones asociadas con la actividad de sting
WO2023137034A1 (en) * 2022-01-12 2023-07-20 Ifm Due, Inc. Compounds and compositions for treating conditions associated with sting activity
CN116554170A (zh) * 2023-04-26 2023-08-08 上海大学 4-氟-7-氮杂吲哚的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1012976A (en) * 1909-03-25 1911-12-26 Adolf Bordt Adding-machine.
WO2003028724A1 (en) * 2001-10-04 2003-04-10 Smithkline Beecham Corporation Chk1 kinase inhibitors
US7531553B2 (en) * 2003-03-21 2009-05-12 Amgen Inc. Heterocyclic compounds and methods of use
US20050130954A1 (en) * 2003-11-21 2005-06-16 Mitchell Ian S. AKT protein kinase inhibitors
CN101959887B (zh) * 2008-01-08 2013-07-31 阵列生物制药公司 作为激酶抑制剂的吡咯并吡啶
JP5386508B2 (ja) 2008-01-22 2014-01-15 ヴァーナリス アールアンドディー リミテッド インドリル−ピリドン誘導体類
AR071717A1 (es) * 2008-05-13 2010-07-07 Array Biopharma Inc Pirrolo[2,3-b]piridinas inhibidoras de quinasas chk1 y chk2,composiciones farmaceuticas que las contienen,proceso para prepararlas y uso de las mismas en el tratamiento y prevencion del cancer.
US20110124654A1 (en) 2008-06-11 2011-05-26 Huifen Chen Diazacarbazoles and methods of use
MX2012001419A (es) * 2009-08-06 2012-03-16 Merck Patent Gmbh Compuestos biciclicos novedosos de urea.
WO2011146313A1 (en) * 2010-05-19 2011-11-24 The University Of North Carolina At Chapel Hill Pyrazolopyrimidine compounds for the treatment of cancer
GB201201566D0 (en) 2012-01-30 2012-03-14 Vernalis R&D Ltd New chemical compounds

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