JP2015505555A5 - - Google Patents
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- Publication number
- JP2015505555A5 JP2015505555A5 JP2014555310A JP2014555310A JP2015505555A5 JP 2015505555 A5 JP2015505555 A5 JP 2015505555A5 JP 2014555310 A JP2014555310 A JP 2014555310A JP 2014555310 A JP2014555310 A JP 2014555310A JP 2015505555 A5 JP2015505555 A5 JP 2015505555A5
- Authority
- JP
- Japan
- Prior art keywords
- inhibition
- cancer
- compound
- protein kinase
- autoimmune disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1201566.5A GB201201566D0 (en) | 2012-01-30 | 2012-01-30 | New chemical compounds |
| GB1201566.5 | 2012-01-30 | ||
| PCT/GB2013/050212 WO2013114113A1 (en) | 2012-01-30 | 2013-01-30 | 1h-pyrrolo[2,3-b] pyridine derivatives and their use as kinase inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015505555A JP2015505555A (ja) | 2015-02-23 |
| JP2015505555A5 true JP2015505555A5 (cg-RX-API-DMAC7.html) | 2015-11-12 |
| JP6199316B2 JP6199316B2 (ja) | 2017-09-20 |
Family
ID=45876325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014555310A Expired - Fee Related JP6199316B2 (ja) | 2012-01-30 | 2013-01-30 | １Ｈ−ピロロ［２，３−ｂ］ピリジン誘導体およびキナーゼ阻害剤としてのその使用 |
Country Status (21)
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201201566D0 (en) | 2012-01-30 | 2012-03-14 | Vernalis R&D Ltd | New chemical compounds |
| KR102096679B1 (ko) * | 2012-04-23 | 2020-04-02 | 제넨테크, 인크. | 화합물의 제조를 위한 중간체 및 방법 |
| JP6463758B2 (ja) * | 2013-08-22 | 2019-02-06 | ジェネンテック， インコーポレイテッド | 化合物の調製方法 |
| CN104829609B (zh) * | 2014-02-11 | 2016-08-03 | 北大方正集团有限公司 | 取代的吡啶并嘧啶化合物及其制备方法和应用 |
| MA41559A (fr) | 2015-09-08 | 2017-12-26 | Taiho Pharmaceutical Co Ltd | Composé de pyrimidine condensé ou un sel de celui-ci |
| US10032914B2 (en) * | 2015-10-20 | 2018-07-24 | Taiwan Semiconductor Manufacturing Co., Ltd. | Semiconductor device and manufacturing method thereof |
| EP3269370B1 (en) | 2016-02-23 | 2020-01-08 | Taiho Pharmaceutical Co., Ltd. | Novel condensed pyrimidine compound or salt thereof |
| EP3674325A4 (en) | 2017-08-21 | 2021-11-03 | Taiho Pharmaceutical Co., Ltd. | FUSION PROTEIN OF DCTN1 PROTEIN WITH RET PROTEIN |
| TW202043198A (zh) | 2019-01-17 | 2020-12-01 | 美商Ｉｆｍ Ｄｕｅ有限公司 | 用於治療與sting活性相關之病況的化合物及組合物 |
| CN111518096B (zh) | 2019-02-02 | 2022-02-11 | 江苏威凯尔医药科技有限公司 | 两面神激酶jak家族抑制剂及其制备和应用 |
| WO2021019514A1 (en) | 2019-08-01 | 2021-02-04 | Integral Biosciences Pvt. Ltd. | Heterocyclic compounds as kinase inhibitor and uses thereof |
| IT202000005527A1 (it) * | 2020-03-16 | 2021-09-16 | Univ Degli Studi Di Trento | Trattamento terapeutico di cromatinopatie |
| TW202216685A (zh) * | 2020-07-15 | 2022-05-01 | 美商Ｉｆｍ Ｄｕｅ有限公司 | 用於治療與sting活性相關的病狀之化合物及組合物 |
| EP4182310A1 (en) | 2020-07-15 | 2023-05-24 | IFM Due, Inc. | Compounds and compositions for treating conditions associated with sting activity |
| EP4182030A1 (en) * | 2020-07-15 | 2023-05-24 | IFM Due, Inc. | Compounds and compositions for treating conditions associated with sting activity |
| JP2024502474A (ja) | 2021-01-08 | 2024-01-19 | アイエフエム デュー インコーポレイテッド | Ｓｔｉｎｇ活性に関連する状態を治療するための、尿素を有するヘテロ二環式化合物または類似体およびその組成物 |
| US20230250060A1 (en) * | 2022-01-12 | 2023-08-10 | Ifm Due, Inc. | Compounds and compositions for treating conditions associated with sting activity |
| CN116554170A (zh) * | 2023-04-26 | 2023-08-08 | 上海大学 | 4-氟-7-氮杂吲哚的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1012976A (en) * | 1909-03-25 | 1911-12-26 | Adolf Bordt | Adding-machine. |
| WO2003028724A1 (en) * | 2001-10-04 | 2003-04-10 | Smithkline Beecham Corporation | Chk1 kinase inhibitors |
| US7531553B2 (en) * | 2003-03-21 | 2009-05-12 | Amgen Inc. | Heterocyclic compounds and methods of use |
| PH12012501891A1 (en) * | 2003-11-21 | 2013-09-02 | Array Biopharma Inc | Akt protein kinase inhibitors |
| CN101959887B (zh) * | 2008-01-08 | 2013-07-31 | 阵列生物制药公司 | 作为激酶抑制剂的吡咯并吡啶 |
| CA2712959C (en) * | 2008-01-22 | 2015-06-23 | Vernalis (R & D) Ltd | Indolyl-pyridone derivatives having checkpoint kinase 1 inhibitory activity |
| CL2009001152A1 (es) * | 2008-05-13 | 2009-10-16 | Array Biopharma Inc | Compuestos derivados de n-(4-(cicloalquilo nitrogenado-1-il)-1h-pirrolo[2,3-b]piridin-3-il)amida, inhibidores de cinasa; proceso de preparacion; composicion farmaceutica; y su uso para el tratamiento de una enfermedad proliferativa. |
| ES2392489T3 (es) * | 2008-06-11 | 2012-12-11 | Genentech, Inc. | Dicarbazoles y procedimientos de uso |
| WO2011017142A1 (en) * | 2009-08-06 | 2011-02-10 | Merck Patent Gmbh | Novel bicyclic urea compounds |
| EP2571361A4 (en) * | 2010-05-19 | 2013-11-13 | Univ North Carolina | PYRAZOLOPYRIMIDINE COMPOUNDS FOR CANCER TREATMENT |
| GB201201566D0 (en) * | 2012-01-30 | 2012-03-14 | Vernalis R&D Ltd | New chemical compounds |
-
2012
- 2012-01-30 GB GBGB1201566.5A patent/GB201201566D0/en not_active Ceased
-
2013
- 2013-01-30 HU HUE13703121A patent/HUE035332T2/en unknown
- 2013-01-30 EP EP13703121.7A patent/EP2809670B1/en active Active
- 2013-01-30 CA CA2862940A patent/CA2862940C/en active Active
- 2013-01-30 NZ NZ627361A patent/NZ627361A/en not_active IP Right Cessation
- 2013-01-30 AU AU2013213954A patent/AU2013213954B2/en active Active
- 2013-01-30 PL PL13703121T patent/PL2809670T3/pl unknown
- 2013-01-30 EA EA201491376A patent/EA026657B1/ru not_active IP Right Cessation
- 2013-01-30 CN CN201380014717.5A patent/CN104203948A/zh active Pending
- 2013-01-30 PT PT137031217T patent/PT2809670T/pt unknown
- 2013-01-30 CN CN202010405942.3A patent/CN111484493A/zh active Pending
- 2013-01-30 DK DK13703121.7T patent/DK2809670T3/en active
- 2013-01-30 JP JP2014555310A patent/JP6199316B2/ja not_active Expired - Fee Related
- 2013-01-30 IN IN6104DEN2014 patent/IN2014DN06104A/en unknown
- 2013-01-30 CN CN201610920724.7A patent/CN107011341A/zh active Pending
- 2013-01-30 HK HK15100794.1A patent/HK1200447A1/xx unknown
- 2013-01-30 CN CN201610920720.9A patent/CN106866658B/zh active Active
- 2013-01-30 WO PCT/GB2013/050212 patent/WO2013114113A1/en not_active Ceased
- 2013-01-30 BR BR112014018795-9A patent/BR112014018795B1/pt not_active IP Right Cessation
- 2013-01-30 ES ES13703121.7T patent/ES2637340T3/es active Active
- 2013-01-30 MX MX2014009112A patent/MX352927B/es active IP Right Grant
- 2013-01-30 US US14/375,353 patent/US10000481B2/en active Active
-
2014
- 2014-07-10 IL IL233595A patent/IL233595B/en active IP Right Grant
- 2014-07-11 ZA ZA2014/05070A patent/ZA201405070B/en unknown
-
2018
- 2018-06-15 US US16/009,439 patent/US10889582B2/en active Active
-
2020
- 2020-11-30 US US17/107,176 patent/US20210206762A1/en not_active Abandoned
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