JP2015503562A5 - - Google Patents

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Publication number
JP2015503562A5
JP2015503562A5 JP2014550353A JP2014550353A JP2015503562A5 JP 2015503562 A5 JP2015503562 A5 JP 2015503562A5 JP 2014550353 A JP2014550353 A JP 2014550353A JP 2014550353 A JP2014550353 A JP 2014550353A JP 2015503562 A5 JP2015503562 A5 JP 2015503562A5
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JP
Japan
Prior art keywords
disease
methyl
condition
carboxylic acid
pyrazole
Prior art date
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Granted
Application number
JP2014550353A
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English (en)
Japanese (ja)
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JP6132853B2 (ja
JP2015503562A (ja
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Publication date
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Priority claimed from PCT/US2012/070664 external-priority patent/WO2013101598A1/en
Publication of JP2015503562A publication Critical patent/JP2015503562A/ja
Publication of JP2015503562A5 publication Critical patent/JP2015503562A5/ja
Application granted granted Critical
Publication of JP6132853B2 publication Critical patent/JP6132853B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2014550353A 2011-12-27 2012-12-19 全身性抗炎症反応を提供する、複数のプロスタグランジン受容体で作用する化合物 Expired - Fee Related JP6132853B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161580474P 2011-12-27 2011-12-27
US61/580,474 2011-12-27
PCT/US2012/070664 WO2013101598A1 (en) 2011-12-27 2012-12-19 Compounds acting at multiple prostaglandin receptors giving a general anti-inflammatory response

Publications (3)

Publication Number Publication Date
JP2015503562A JP2015503562A (ja) 2015-02-02
JP2015503562A5 true JP2015503562A5 (enExample) 2016-02-18
JP6132853B2 JP6132853B2 (ja) 2017-05-24

Family

ID=47436293

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014550353A Expired - Fee Related JP6132853B2 (ja) 2011-12-27 2012-12-19 全身性抗炎症反応を提供する、複数のプロスタグランジン受容体で作用する化合物

Country Status (6)

Country Link
US (1) US9035071B2 (enExample)
EP (1) EP2797893B1 (enExample)
JP (1) JP6132853B2 (enExample)
AU (1) AU2012362724C1 (enExample)
CA (1) CA2862263C (enExample)
WO (1) WO2013101598A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8859606B2 (en) 2010-07-01 2014-10-14 Allergan, Inc. Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response
WO2014113814A1 (en) * 2013-01-21 2014-07-24 Allergan, Inc. Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response
ITMI20132201A1 (it) * 2013-12-23 2015-06-24 Isagro Spa Processo per la sintesi regioselettiva di pirazoli
AU2019387370A1 (en) 2018-11-30 2021-06-10 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
JP7816164B2 (ja) 2020-11-13 2026-02-18 小野薬品工業株式会社 Ｅｐ４拮抗薬と免疫チェックポイント阻害物質との併用によるがん治療

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
DE19924872A1 (de) * 1999-05-29 2000-11-30 Dresden Arzneimittel Antikonvulsiv wirkende Pyrazolo[3,4-d][1,2,3]triazine und Verfahren zu ihrer Herstellung
US6511999B2 (en) 2000-09-14 2003-01-28 Allergan, Inc. Interheteroaryl 7-oxabicyclic [2.2.1]heptane oxazoles as prostaglandin F2α antagonists
US7273883B2 (en) 2000-09-14 2007-09-25 Allergan, Inc. Prostaglandin EP4 antagonist
US7217725B2 (en) 2000-09-14 2007-05-15 Allergan, Inc. Prostaglandin D2 antagonist
AU2002359365B2 (en) * 2001-11-09 2008-07-10 Gilead Sciences, Inc. A2B adenosine receptor antagonists
US20050014813A1 (en) * 2001-11-13 2005-01-20 Hiroyuki Tawada Process for production of pyrazole compounds
EP1675832B1 (en) 2003-10-24 2008-02-20 Glaxo Group Limited Heterocyclyl compounds
US7449473B2 (en) 2003-10-31 2008-11-11 Cv Therapeutics, Inc. Substituted pyrrolo[3,2-d]pyrimidin-2,4-diones as A2b adenosine receptor antagonists
US7918014B2 (en) 2005-07-13 2011-04-05 Headway Technologies, Inc. Method of manufacturing a CPP structure with enhanced GMR ratio
WO2007014054A2 (en) * 2005-07-22 2007-02-01 Glaxo Group Limted Benzenesulfonamide inhibitor of ccr2 chemokine receptor
WO2008033455A2 (en) * 2006-09-13 2008-03-20 The Institutes For Pharmaceutical Discovery, Llc Biphenyl and heteroaryl phenyl derivatives as protein tyrosine phosphatases inhibitors
WO2008138876A1 (en) * 2007-05-10 2008-11-20 Glaxo Group Limited Pyrazole derivatives as p2x7 modulators
JP2010248183A (ja) * 2009-03-26 2010-11-04 Takeda Chem Ind Ltd 複素環化合物
ES2545865T3 (es) * 2010-01-27 2015-09-16 Boehringer Ingelheim International Gmbh Compuestos de pirazol como antagonistas de CRTH2
US8492424B2 (en) * 2010-07-01 2013-07-23 Allergan, Inc. Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response
EP2457900A1 (en) * 2010-11-25 2012-05-30 Almirall, S.A. New pyrazole derivatives having CRTh2 antagonistic behaviour
JP5999387B2 (ja) * 2011-03-25 2016-09-28 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｃｒｔｈ２拮抗薬としてのピラゾール化合物

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