JP2015502588A - ゲノム及び他の情報を保護及び管理するシステム及び方法 - Google Patents
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Abstract
Description
本出願は2011年10月17日付出願の仮出願番号第61/548161号及び2012年3月29日付出願の仮出願番号第61/617593号の優先権の利益を請求し、それらの全体が参照より本願明細書に組み込まれる。
この特許文献の一部の開示は、著作権の保護を受ける資料を含む。本著作権者は、本特許文書又は本特許の開示事項が米国特許商標局の特許ファイル又は記録に示されているので、本特許文書又は本特許の開示事項を誰かがファクシミリで複写することに異議を申立てないが、その外のものについては全著作権を留保するものである。
Claims (21)
- ヒトゲノムデータに関する信頼性のある計算を行う方法であって、
ゲノムデータセットと、ゲノムデータに作用するように設計されたコンピュータプログラムとを受信することと、
演算処理システムで、前記コンピュータプログラムの信頼性を評価することと、
演算処理システムで、前記ゲノムデータセットの少なくとも一部の信頼性を評価することと、
演算処理システムで、前記コンピュータプログラムが前記ゲノムデータに作用することを許可するか決めるために、前記ゲノムデータに関連するポリシーを評価することと、
前記信頼性およびポリシーの評価が十分なときに、前記ゲノムデータセットの少なくとも一部について、前記コンピュータプログラムを実行すること
を備える方法。 - 前記コンピュータプログラムの信頼性と前記ゲノムデータセットの少なくとも一部の信頼性とを評価すること、及び、前記ゲノムデータに関連するポリシーを評価することは、自動的に実施される、請求項1に記載の方法。
- 前記自動的に実施される評価は、信頼性のある医療コンピュータシステムにより実施される、請求項2に記載の方法。
- 前記コンピュータプログラムの実行の少なくとも一部に基づいて医療診断に有益な診断結果を生成することをさらに備える、請求項1に記載の方法。
- 前記コンピュータプログラムの信頼性と前記ゲノムデータセットの少なくとも一部の信頼性との前記評価の少なくとも一部に基づいて、前記生成された診断結果の信頼性を保証することをさらに備える、請求項4に記載の方法。
- 前記コンピュータプログラムの信頼性の評価は、受信したコンピュータプログラムとともにパッケージ化された少なくとも一つのデジタル署名を検証することを含む、請求項1に記載の方法。
- 前記受信したコンピュータプログラムとともにパッケージ化された情報に基づいて前記コンピュータプログラムのデータ条件を判断することをさらに備える、請求項1に記載の方法。
- 前記ゲノムデータセットの少なくとも一部の信頼性の評価は、前記受信したゲノムデータセットとともにパッケージ化された少なくとも一つのデジタル署名を検証することを含む、請求項1に記載の方法。
- 前記ゲノムデータセットを、データフォーマット異常について確認することをさらに備える、請求項1に記載の方法。
- 1又は複数のプライバシーポリシーに基づいて、前記ゲノムデータセットと関連するプライバシーを自動的に保つことをさらに備える、請求項1に記載の方法。
- 前記コンピュータプログラムは、一連の実行可能プログラムを含む、請求項1に記載の方法。
- ゲノムデータセットの少なくとも一部とコンピュータプログラムとを格納するよう構成された安全な記憶装置と、
前記コンピュータプログラムの信頼性を評価し、前記ゲノムデータセットの少なくとも一部の信頼性を評価し、前記ゲノムデータセットの少なくとも一部に対する前記コンピュータプログラムの許可を評価し、前記信頼性評価および前記許可評価が十分なときに、前記ゲノムデータセットの少なくとも一部に対して前記コンピュータプログラムを実行するようプログラムされ構成された安全な演算処理システムと
を備える信頼性のある医療コンピュータシステム。 - 前記コンピュータプログラムの信頼性の評価は、前記コンピュータプログラムとともにパッケージ化された少なくとも一つのデジタル署名を検証することを含む、請求項12に記載のシステム。
- 前記ゲノムデータセットの少なくとも一部の信頼性の評価は、前記ゲノムデータセットともにパッケージ化された少なくとも一つのデジタル署名を検証することを含む、請求項12に記載のシステム。
- 前記安全な演算処理システムは、さらに、前記コンピュータプログラムの実行の少なくとも一部に基づいて医療診断に有益な診断結果を生成するようにプログラムされ構成される、請求項12に記載のシステム。
- 前記安全な演算処理システムは、さらに、前記コンピュータプログラムの信頼性と前記ゲノムデータセットの少なくとも一部の信頼性との前記評価の少なくとも一部に基づいて、前記生成された診断結果の信頼性を保証するようにプログラムされ構成される、請求項15に記載のシステム。
- DNA配列決定装置からゲノムデータを受信することと、
前記受信したゲノムデータを暗号化することと、
前記ゲノムデータについての後の検証を容易にするデジタル署名を生成することと、
前記ゲノムデータへのアクセスまたは使用を管理するよう構成されるポリシー情報を前記ゲノムデータと関連づけることと、
前記暗号化されたゲノムデータとともに前記デジタル署名をパッケージ化すること
を備えるパッケージ化されたゲノムデータを生成する方法。 - 前記デジタル署名は、前記DNA配列決定装置に関連する秘密鍵を使用して生成される、請求項17に記載の方法。
- 前記DNA配列決定は配列決定施設によって行われ、前記デジタル署名は前記配列決定施設に関連する秘密鍵を使用して生成される、請求項17に記載の方法。
- 前記ゲノムデータを生成するために用いるサンプルについてのサンプル収集情報およびサンプル・ソース情報を記述するメタデータを、前記暗号化されたゲノムデータとともにパッケージ化する、請求項17に記載の方法。
- 第1の事業体から第1のデータセットを受信することと
第2の事業体から第2にデータセットを受信することと、
少なくとも第3の事業体から、前記第1のデータセットの少なくとも一部と前記第2のデータセットの少なくとも一部とを含むデータセットに作用するように設計されたコンピュータプログラムを受信することと、
演算処理システムで、前記コンピュータプログラムの信頼性を評価することと、
演算処理システムで、前記第1のデータセットと前記第2のデータセットとの少なくとも一部の信頼性を評価することと、
演算処理システムで、前記コンピュータプログラムが前記第1のデータセットに作用することを許可するかを決めるために、前記第1のデータセットに関連する第1のポリシーを評価することと、
演算処理システムで、前記コンピュータプログラムが前記第2のデータセットに作用することを許可するかを決めるために、前記第2のデータセットに関連する第2のポリシーを評価することと、
前記信頼性およびポリシーの評価が十分なときに、前記第1のデータセットの少なくとも一部と前記第2のデータセットの少なくとも一部とについて、前記コンピュータプログラムを実行して、前記第1のデータセットの少なくとも一部と前記第2のデータセットの少なくとも一部とによる結果を作成する、信頼性のある計算を行う方法。
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CA2852916A1 (en) | 2013-04-25 |
EP2769322A1 (en) | 2014-08-27 |
US20230074310A1 (en) | 2023-03-09 |
ZA201403056B (en) | 2015-07-29 |
AU2012326132A1 (en) | 2014-05-08 |
WO2013059368A1 (en) | 2013-04-25 |
US20200242557A1 (en) | 2020-07-30 |
CN107301332A (zh) | 2017-10-27 |
US20130096943A1 (en) | 2013-04-18 |
CN104054084A (zh) | 2014-09-17 |
JP6199297B2 (ja) | 2017-09-20 |
AU2016201692A1 (en) | 2016-04-07 |
EP2769322A4 (en) | 2015-03-04 |
US10621550B2 (en) | 2020-04-14 |
CN104054084B (zh) | 2017-07-28 |
CN107301332B (zh) | 2021-10-29 |
US11481729B2 (en) | 2022-10-25 |
BR112014009413A2 (pt) | 2017-04-18 |
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