JP2015502340A5 - - Google Patents

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Publication number
JP2015502340A5
JP2015502340A5 JP2014539044A JP2014539044A JP2015502340A5 JP 2015502340 A5 JP2015502340 A5 JP 2015502340A5 JP 2014539044 A JP2014539044 A JP 2014539044A JP 2014539044 A JP2014539044 A JP 2014539044A JP 2015502340 A5 JP2015502340 A5 JP 2015502340A5
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JP
Japan
Prior art keywords
seq
antibody
variable region
chain variable
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014539044A
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English (en)
Japanese (ja)
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JP2015502340A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2012/062124 external-priority patent/WO2013063395A1/en
Publication of JP2015502340A publication Critical patent/JP2015502340A/ja
Publication of JP2015502340A5 publication Critical patent/JP2015502340A5/ja
Pending legal-status Critical Current

Links

JP2014539044A 2011-10-27 2012-10-26 iNKTに対するヒト化抗体 Pending JP2015502340A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161552337P 2011-10-27 2011-10-27
US61/552,337 2011-10-27
PCT/US2012/062124 WO2013063395A1 (en) 2011-10-27 2012-10-26 Humanized antibodies to inkt

Publications (2)

Publication Number Publication Date
JP2015502340A JP2015502340A (ja) 2015-01-22
JP2015502340A5 true JP2015502340A5 (https=) 2015-12-17

Family

ID=48168549

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014539044A Pending JP2015502340A (ja) 2011-10-27 2012-10-26 iNKTに対するヒト化抗体

Country Status (13)

Country Link
US (1) US9932402B2 (https=)
EP (1) EP2755688A4 (https=)
JP (1) JP2015502340A (https=)
KR (1) KR20140093964A (https=)
CN (1) CN103945867B (https=)
AU (1) AU2012328588C1 (https=)
BR (1) BR112014009962A2 (https=)
CA (1) CA2853719A1 (https=)
HK (2) HK1199837A1 (https=)
IL (1) IL232017A0 (https=)
RU (1) RU2014120694A (https=)
SG (1) SG11201401319XA (https=)
WO (1) WO2013063395A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014244444A1 (en) * 2013-03-14 2015-09-24 Amgen Inc. CHRDL-1 antigen binding proteins and methods of treatment
WO2015069697A2 (en) * 2013-11-05 2015-05-14 Nkt Therapeutics Inc. Combination therapy
SG11201605580RA (en) 2014-01-10 2016-10-28 Anaptysbio Inc Antibodies directed against interleukin-33 (il-33)
WO2015121393A1 (en) * 2014-02-14 2015-08-20 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of acute exacerbations of chronic obstructive pulmonary disease
TWI664190B (zh) * 2014-06-27 2019-07-01 美商C2N醫療診斷有限責任公司 人類化抗-tau抗體
WO2016013672A1 (ja) * 2014-07-25 2016-01-28 国立研究開発法人理化学研究所 メモリーインバリアントnkt細胞マーカー
WO2016018850A1 (en) * 2014-07-28 2016-02-04 Nkt Therapeutics Inc. Combination therapy with il-12
US11933786B2 (en) 2015-03-30 2024-03-19 Stcube, Inc. Antibodies specific to glycosylated PD-L1 and methods of use thereof
KR102809728B1 (ko) 2015-12-02 2025-05-21 주식회사 에스티큐브 글리코실화된 pd-1에 대해 특이적인 항체 및 이의 사용 방법
KR20180130541A (ko) 2016-03-29 2018-12-07 주식회사 에스티큐브앤컴퍼니 글리코실화된 면역체크포인트 단백질에 특이적으로 결합하는 항체를 선택하는 방법
JP6967528B2 (ja) 2016-04-04 2021-11-17 バイオベラティブ ユーエスエー インコーポレイテッド 抗補体Bb因子抗体及びその使用
EP3487883B1 (en) 2016-07-20 2023-01-04 Stcube, Inc. Methods of cancer treatment and therapy using a combination of antibodies that bind glycosylated pd-l1
WO2018052818A1 (en) * 2016-09-16 2018-03-22 Henlix, Inc. Anti-pd-1 antibodies
WO2020156335A1 (zh) * 2019-01-29 2020-08-06 上海交通大学 一种嵌合抗原受体及其应用
KR20230004686A (ko) * 2020-04-20 2023-01-06 젠자임 코포레이션 인간화 항-보체 인자 Bb 항체 및 그의 용도
CN115666586A (zh) * 2020-04-23 2023-01-31 加州大学评议会 通过激活iNKT细胞清除衰老细胞
CN117222414A (zh) 2021-03-01 2023-12-12 脱落性治疗公司 用于激活恒定自然杀伤t-细胞的化合物和用于消除炎性衰老细胞的方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7119248B1 (en) 1994-04-12 2006-10-10 Miltenyi Biotec Gmbh Antibodies against epitopes with homology to self antigens, methods of preparation and applications thereof
WO1997016203A1 (en) 1995-11-01 1997-05-09 Genetics Institute, Inc. Methods for administration of il-12
WO1999034209A1 (en) 1997-12-31 1999-07-08 The Brigham And Women's Hospital, Inc. DIAGNOSTIC AND THERAPEUTIC METHODS BASED UPON Vα24JαQ T CELLS
DK2336187T3 (en) * 2000-06-19 2016-08-22 Beth Israel Deaconess Medical Ct Inc Compositions and Methods of monoclonal and polyclonal antibodies which are specific for T-cell subpopulations
US7101977B2 (en) * 2001-07-17 2006-09-05 Research Development Foundation Therapeutic agents comprising pro-apoptotic proteins
HK1079882B (en) 2002-06-14 2011-11-25 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of treating and preventing colitis involving il-13 and nk-t cells
US9809654B2 (en) * 2002-09-27 2017-11-07 Vaccinex, Inc. Targeted CD1d molecules
CA2577009C (en) 2004-08-27 2017-05-02 Albert Einstein College Of Medicine, Inc. Ceramide derivatives as modulators of immunity and autoimmunity
CA2584971C (en) * 2004-11-02 2013-08-06 The Board Of Trustees Of The Leland Stanford Junior University Methods for inhibition of nkt cells
PE20071101A1 (es) 2005-08-31 2007-12-21 Amgen Inc Polipeptidos y anticuerpos
WO2008140487A2 (en) * 2006-11-14 2008-11-20 Elusys Therapeutics, Inc. Improved staphylococcal protein a mono- and bispecific antibodies and methods of their use
US20100035843A1 (en) 2007-02-12 2010-02-11 The General Hospital Corporation Methods for attenuating allergen-induced airway hyperreactivity using cd1d dependent antagonists
US8012484B2 (en) * 2007-04-12 2011-09-06 University Of Virginia Patent Foundation Method of treating ischemia reperfusion injury by inhibiting NKT cell activity
US20090028849A1 (en) 2007-07-24 2009-01-29 O'brien Rebecca L Agents and methods for inhibition of airway hyperresponsiveness
US20110300154A1 (en) * 2007-08-21 2011-12-08 Children's Medical Center Corporation Treatment of airway hyperreactivity
EP2222700A2 (en) 2007-11-27 2010-09-01 Medtronic, Inc. Humanized anti-amyloid beta antibodies
GB0902916D0 (en) 2009-02-20 2009-04-08 Fusion Antibodies Ltd Antibody therapy
WO2011112889A2 (en) 2010-03-12 2011-09-15 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services β-MANNOSYLCERAMIDE AND STIMULATION OF NKT CELL ANTI-TUMOR IMMUNITY
EP2575824A4 (en) 2010-05-24 2014-02-19 Childrens Medical Center METHOD FOR THE TREATMENT AND PREVENTION OF INFLAMMATORY DISEASES
US9365496B2 (en) 2011-11-30 2016-06-14 Ludwig Institute For Cancer Research iNKT cell modulators and methods of using the same
WO2015069697A2 (en) 2013-11-05 2015-05-14 Nkt Therapeutics Inc. Combination therapy
WO2016018850A1 (en) 2014-07-28 2016-02-04 Nkt Therapeutics Inc. Combination therapy with il-12

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