JP2015501782A5 - - Google Patents
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- Publication number
- JP2015501782A5 JP2015501782A5 JP2014539984A JP2014539984A JP2015501782A5 JP 2015501782 A5 JP2015501782 A5 JP 2015501782A5 JP 2014539984 A JP2014539984 A JP 2014539984A JP 2014539984 A JP2014539984 A JP 2014539984A JP 2015501782 A5 JP2015501782 A5 JP 2015501782A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- aryl
- heteroaryl
- group
- perfluoroalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CNC(CC1)CCC1N(*)c1nc(C=C(C(N2*)=O)SC2=O)ccn1 Chemical compound CNC(CC1)CCC1N(*)c1nc(C=C(C(N2*)=O)SC2=O)ccn1 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161555617P | 2011-11-04 | 2011-11-04 | |
| US61/555,617 | 2011-11-04 | ||
| PCT/US2012/061597 WO2013066684A1 (en) | 2011-11-04 | 2012-10-24 | Aminopyrimidine kinase inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015501782A JP2015501782A (ja) | 2015-01-19 |
| JP2015501782A5 true JP2015501782A5 (enExample) | 2015-12-17 |
| JP6215832B2 JP6215832B2 (ja) | 2017-10-18 |
Family
ID=47116510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014539984A Expired - Fee Related JP6215832B2 (ja) | 2011-11-04 | 2012-10-24 | アミノピリミジンキナーゼ阻害剤 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US8927525B2 (enExample) |
| EP (1) | EP2776432B1 (enExample) |
| JP (1) | JP6215832B2 (enExample) |
| KR (1) | KR101990605B1 (enExample) |
| CN (1) | CN104011046B (enExample) |
| AU (1) | AU2012332931B2 (enExample) |
| BR (1) | BR112014010563B1 (enExample) |
| CA (1) | CA2853454C (enExample) |
| ES (1) | ES2629690T3 (enExample) |
| IL (1) | IL232234A0 (enExample) |
| MX (1) | MX347191B (enExample) |
| PL (1) | PL2776432T3 (enExample) |
| RU (1) | RU2674017C2 (enExample) |
| WO (1) | WO2013066684A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102884062B (zh) * | 2009-12-23 | 2016-08-03 | 嘉世高制药公司 | 氨基嘧啶激酶抑制剂 |
| AU2012245344B2 (en) * | 2011-04-22 | 2017-11-09 | Jasco Pharmaceuticals, LLC | Aminopyrimidine kinase inhibitors |
| CN104011046B (zh) | 2011-11-04 | 2017-05-03 | 嘉世高制药公司 | 氨基嘧啶激酶抑制剂 |
| JP6437452B2 (ja) | 2013-01-14 | 2018-12-12 | インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅ Ｈｏｌｄｉｎｇｓ Ｃｏｒｐｏｒａｔｉｏｎ | Ｐｉｍキナーゼ阻害剤として有用な二環式芳香族カルボキサミド化合物 |
| LT2945939T (lt) | 2013-01-15 | 2020-07-27 | Incyte Holdings Corporation | Triazolkarboksamidai ir piridinkarboksamido junginiai, naudotini kaip pim kinazės inhibitoriai |
| EP3036238A1 (en) | 2013-08-23 | 2016-06-29 | Incyte Corporation | Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors |
| US9580418B2 (en) | 2014-07-14 | 2017-02-28 | Incyte Corporation | Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors |
| US9822124B2 (en) | 2014-07-14 | 2017-11-21 | Incyte Corporation | Bicyclic heteroaromatic carboxamide compounds useful as Pim kinase inhibitors |
| US9540347B2 (en) | 2015-05-29 | 2017-01-10 | Incyte Corporation | Pyridineamine compounds useful as Pim kinase inhibitors |
| JP7083309B2 (ja) | 2015-08-04 | 2022-06-10 | イッサム リサーチ ディベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティ オブ エルサレム エルティーディー． | ピラゾールピリミジン誘導体及びその使用 |
| AR105967A1 (es) | 2015-09-09 | 2017-11-29 | Incyte Corp | Sales de un inhibidor de pim quinasa |
| WO2017059251A1 (en) | 2015-10-02 | 2017-04-06 | Incyte Corporation | Heterocyclic compounds useful as pim kinase inhibitors |
| US11072599B2 (en) | 2017-02-01 | 2021-07-27 | Biotheryx, Inc. | Pyrazole compounds and uses thereof |
| TW201924683A (zh) | 2017-12-08 | 2019-07-01 | 美商英塞特公司 | 用於治療骨髓增生性贅瘤的低劑量組合療法 |
| KR20220081359A (ko) | 2019-10-09 | 2022-06-15 | 바이엘 악티엔게젤샤프트 | 살충제로서의 신규 헤테로아릴-트리아졸 화합물 |
| WO2025132870A1 (en) * | 2023-12-21 | 2025-06-26 | Glaxosmithkline Intellectual Property (No.4) Limited | Chemical compounds and uses thereof |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW245716B (enExample) | 1992-12-28 | 1995-04-21 | Takeda Pharm Industry Co | |
| IL113112A (en) * | 1994-03-28 | 2000-06-01 | Nissan Chemical Ind Ltd | Pyridine substituted thiazolidinediones and pharmaceutical compositions comprising them |
| US5955481A (en) | 1994-03-28 | 1999-09-21 | Nissan Chemical Industries, Ltd. | Pyridine type thiazolidines |
| AU712802B2 (en) | 1994-10-20 | 1999-11-18 | Nippon Chemiphar Co. Ltd. | Quinoline derivatives |
| BRPI0512261A (pt) | 2004-06-17 | 2008-02-26 | Wyeth Corp | antagonistas de receptor de hormÈnio liberador de gonadotropina |
| PL1786812T3 (pl) * | 2004-09-03 | 2012-04-30 | Merck Serono Sa | Pirydynometylenoazolidynony i ich zastosowanie jako inhibitorów fosfoinozytydów |
| US20090042773A1 (en) | 2004-10-12 | 2009-02-12 | Reinhard Wetzker | P13 kinase gamma inhibitors for the treatment of anaemia |
| EP1916249A1 (en) | 2006-10-10 | 2008-04-30 | LEK Pharmaceuticals D.D. | 3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(thio)oxo-2-(thio)oxo-azolidin-5-ylidene derivatives as antibacterial agents |
| WO2009064486A2 (en) * | 2007-11-15 | 2009-05-22 | Musc Foundation For Research Development | Inhibitors of pim protein kinases, compositions, and methods for treating cancer |
| US8252823B2 (en) | 2008-01-28 | 2012-08-28 | New York University | Oxazole and thiazole compounds as beta-catenin modulators and uses thereof |
| MX2011004553A (es) | 2008-10-29 | 2011-07-20 | Sirtris Pharmaceuticals Inc | Piridina, piridina biciclica y analogos relacionados como moduladores de sirtuina. |
| US20100331315A1 (en) * | 2009-06-18 | 2010-12-30 | Mustapha Haddach | Rhodanines and related heterocycles as kinase inhibitors |
| CN102884062B (zh) | 2009-12-23 | 2016-08-03 | 嘉世高制药公司 | 氨基嘧啶激酶抑制剂 |
| AU2012245344B2 (en) | 2011-04-22 | 2017-11-09 | Jasco Pharmaceuticals, LLC | Aminopyrimidine kinase inhibitors |
| CN104011046B (zh) | 2011-11-04 | 2017-05-03 | 嘉世高制药公司 | 氨基嘧啶激酶抑制剂 |
-
2012
- 2012-10-24 CN CN201280053781.XA patent/CN104011046B/zh not_active Expired - Fee Related
- 2012-10-24 EP EP12780393.0A patent/EP2776432B1/en active Active
- 2012-10-24 MX MX2014005052A patent/MX347191B/es active IP Right Grant
- 2012-10-24 JP JP2014539984A patent/JP6215832B2/ja not_active Expired - Fee Related
- 2012-10-24 US US13/659,343 patent/US8927525B2/en active Active
- 2012-10-24 CA CA2853454A patent/CA2853454C/en active Active
- 2012-10-24 RU RU2014122344A patent/RU2674017C2/ru active
- 2012-10-24 PL PL12780393T patent/PL2776432T3/pl unknown
- 2012-10-24 BR BR112014010563-4A patent/BR112014010563B1/pt not_active IP Right Cessation
- 2012-10-24 KR KR1020147014718A patent/KR101990605B1/ko not_active Expired - Fee Related
- 2012-10-24 AU AU2012332931A patent/AU2012332931B2/en active Active
- 2012-10-24 ES ES12780393.0T patent/ES2629690T3/es active Active
- 2012-10-24 WO PCT/US2012/061597 patent/WO2013066684A1/en not_active Ceased
-
2014
- 2014-04-24 IL IL232234A patent/IL232234A0/en active IP Right Grant
- 2014-12-19 US US14/577,079 patent/US9629840B2/en active Active
-
2016
- 2016-12-09 US US15/374,013 patent/US10336743B2/en active Active
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