JP2015501782A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015501782A5 JP2015501782A5 JP2014539984A JP2014539984A JP2015501782A5 JP 2015501782 A5 JP2015501782 A5 JP 2015501782A5 JP 2014539984 A JP2014539984 A JP 2014539984A JP 2014539984 A JP2014539984 A JP 2014539984A JP 2015501782 A5 JP2015501782 A5 JP 2015501782A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- aryl
- heteroaryl
- group
- perfluoroalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CNC(CC1)CCC1N(*)c1nc(C=C(C(N2*)=O)SC2=O)ccn1 Chemical compound CNC(CC1)CCC1N(*)c1nc(C=C(C(N2*)=O)SC2=O)ccn1 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161555617P | 2011-11-04 | 2011-11-04 | |
| US61/555,617 | 2011-11-04 | ||
| PCT/US2012/061597 WO2013066684A1 (en) | 2011-11-04 | 2012-10-24 | Aminopyrimidine kinase inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015501782A JP2015501782A (ja) | 2015-01-19 |
| JP2015501782A5 true JP2015501782A5 (enExample) | 2015-12-17 |
| JP6215832B2 JP6215832B2 (ja) | 2017-10-18 |
Family
ID=47116510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014539984A Expired - Fee Related JP6215832B2 (ja) | 2011-11-04 | 2012-10-24 | アミノピリミジンキナーゼ阻害剤 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US8927525B2 (enExample) |
| EP (1) | EP2776432B1 (enExample) |
| JP (1) | JP6215832B2 (enExample) |
| KR (1) | KR101990605B1 (enExample) |
| CN (1) | CN104011046B (enExample) |
| AU (1) | AU2012332931B2 (enExample) |
| BR (1) | BR112014010563B1 (enExample) |
| CA (1) | CA2853454C (enExample) |
| ES (1) | ES2629690T3 (enExample) |
| IL (1) | IL232234A0 (enExample) |
| MX (1) | MX347191B (enExample) |
| PL (1) | PL2776432T3 (enExample) |
| RU (1) | RU2674017C2 (enExample) |
| WO (1) | WO2013066684A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011079274A1 (en) * | 2009-12-23 | 2011-06-30 | Jasco Pharmaceuticals, LLC | Aminopyrimidine kinase inhibitors |
| WO2012145617A2 (en) * | 2011-04-22 | 2012-10-26 | Jasco Pharmaceuticals, LLC | Aminopyrimidine kinase inhibitors |
| BR112014010563B1 (pt) | 2011-11-04 | 2021-01-12 | Jasco Pharmaceuticals, LLC | compostos inibidores da aminopirimidina quinase |
| EP2943485B1 (en) | 2013-01-14 | 2017-09-20 | Incyte Holdings Corporation | Bicyclic aromatic carboxamide compounds useful as pim kinase inhibitors |
| TWI662030B (zh) | 2013-01-15 | 2019-06-11 | 英塞特控股公司 | 適用作ｐｉｍ激酶抑制劑之噻唑甲醯胺及吡啶甲醯胺化合物 |
| US9556197B2 (en) | 2013-08-23 | 2017-01-31 | Incyte Corporation | Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors |
| WO2016010897A1 (en) | 2014-07-14 | 2016-01-21 | Incyte Corporation | Bicyclic heteroaromatic carboxamide compounds useful as pim kinase inhibitors |
| US9580418B2 (en) | 2014-07-14 | 2017-02-28 | Incyte Corporation | Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors |
| WO2016196244A1 (en) | 2015-05-29 | 2016-12-08 | Incyte Corporation | Pyridineamine compounds useful as pim kinase inhibitors |
| RS62728B1 (sr) | 2015-08-04 | 2022-01-31 | Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd | Derivat pirazol pirimidina i njegove upotrebe |
| AR105967A1 (es) | 2015-09-09 | 2017-11-29 | Incyte Corp | Sales de un inhibidor de pim quinasa |
| WO2017059251A1 (en) | 2015-10-02 | 2017-04-06 | Incyte Corporation | Heterocyclic compounds useful as pim kinase inhibitors |
| WO2018142393A1 (en) | 2017-02-01 | 2018-08-09 | Yissum Research Development Company Of The Hebrew | N1 -(4-(5-(cyclopropylmethyl)-1 -methyl-1 h-pyrazol-4-yl)pyridin-2-yl)cyclohexane-1,4-diamine derivatives and related compounds as ck1 and/or iraki inhibitors for treating cancer |
| TW201924683A (zh) | 2017-12-08 | 2019-07-01 | 美商英塞特公司 | 用於治療骨髓增生性贅瘤的低劑量組合療法 |
| CN117567338A (zh) | 2019-10-09 | 2024-02-20 | 拜耳公司 | 作为农药的新的杂芳基三唑化合物 |
| IL328905A (en) * | 2023-12-21 | 2026-08-01 | Glaxosmithkline Intellectual Property No 4 Ltd | Chemical compounds and their uses |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW245716B (enExample) | 1992-12-28 | 1995-04-21 | Takeda Pharm Industry Co | |
| US5955481A (en) | 1994-03-28 | 1999-09-21 | Nissan Chemical Industries, Ltd. | Pyridine type thiazolidines |
| IL113112A (en) * | 1994-03-28 | 2000-06-01 | Nissan Chemical Ind Ltd | Pyridine substituted thiazolidinediones and pharmaceutical compositions comprising them |
| WO1996012719A1 (en) | 1994-10-20 | 1996-05-02 | Nippon Chemiphar Co., Ltd. | Quinoline derivative |
| EP1758895A1 (en) | 2004-06-17 | 2007-03-07 | Wyeth a Corporation of the State of Delaware | Gonadotropin releasing hormone receptor antagonists |
| KR101229647B1 (ko) * | 2004-09-03 | 2013-02-05 | 메르크 세로노 에스.에이. | 피리딘 메틸렌 아조리디논 및 포스포이노시타이드 저해제의용도 |
| MX2007004302A (es) | 2004-10-12 | 2007-06-07 | Applied Research Systems | Inhibidores de pi3 cinasa gamma para el tratamiento de anemia. |
| EP1916249A1 (en) | 2006-10-10 | 2008-04-30 | LEK Pharmaceuticals D.D. | 3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(thio)oxo-2-(thio)oxo-azolidin-5-ylidene derivatives as antibacterial agents |
| CA2743756A1 (en) * | 2007-11-15 | 2009-05-22 | Musc Foundation For Research Development | Inhibitors of pim protein kinases, compositions, and methods for treating cancer |
| US8252823B2 (en) | 2008-01-28 | 2012-08-28 | New York University | Oxazole and thiazole compounds as beta-catenin modulators and uses thereof |
| EP2350051A4 (en) | 2008-10-29 | 2012-05-30 | Sirtris Pharmaceuticals Inc | PYRIDINE, BICYCLIC PYRIDINE AND ITS ANALOGS AS SIRTUINE MODULATORS |
| WO2010148351A1 (en) * | 2009-06-18 | 2010-12-23 | Cylene Pharmaceuticals, Inc. | Rhodanines and related heterocycles as kinase inhibitors |
| WO2011079274A1 (en) | 2009-12-23 | 2011-06-30 | Jasco Pharmaceuticals, LLC | Aminopyrimidine kinase inhibitors |
| WO2012145617A2 (en) * | 2011-04-22 | 2012-10-26 | Jasco Pharmaceuticals, LLC | Aminopyrimidine kinase inhibitors |
| BR112014010563B1 (pt) | 2011-11-04 | 2021-01-12 | Jasco Pharmaceuticals, LLC | compostos inibidores da aminopirimidina quinase |
-
2012
- 2012-10-24 BR BR112014010563-4A patent/BR112014010563B1/pt not_active IP Right Cessation
- 2012-10-24 WO PCT/US2012/061597 patent/WO2013066684A1/en not_active Ceased
- 2012-10-24 ES ES12780393.0T patent/ES2629690T3/es active Active
- 2012-10-24 AU AU2012332931A patent/AU2012332931B2/en active Active
- 2012-10-24 KR KR1020147014718A patent/KR101990605B1/ko not_active Expired - Fee Related
- 2012-10-24 CA CA2853454A patent/CA2853454C/en active Active
- 2012-10-24 MX MX2014005052A patent/MX347191B/es active IP Right Grant
- 2012-10-24 EP EP12780393.0A patent/EP2776432B1/en active Active
- 2012-10-24 JP JP2014539984A patent/JP6215832B2/ja not_active Expired - Fee Related
- 2012-10-24 RU RU2014122344A patent/RU2674017C2/ru active
- 2012-10-24 CN CN201280053781.XA patent/CN104011046B/zh not_active Expired - Fee Related
- 2012-10-24 PL PL12780393T patent/PL2776432T3/pl unknown
- 2012-10-24 US US13/659,343 patent/US8927525B2/en active Active
-
2014
- 2014-04-24 IL IL232234A patent/IL232234A0/en active IP Right Grant
- 2014-12-19 US US14/577,079 patent/US9629840B2/en active Active
-
2016
- 2016-12-09 US US15/374,013 patent/US10336743B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2014122344A (ru) | Аминопиримидиновые ингибиторы киназ | |
| RU2477723C2 (ru) | Ингибиторы протеинкиназ (варианты), их применение для лечения онкологических заболеваний и фармацевтическая композиция на их основе | |
| JP2016503799A5 (enExample) | ||
| JP2019518766A5 (enExample) | ||
| ME02452B (me) | Sredstva za induciranje apoptoze namijenjena liječenju raka i imunih i autoimunih bolesti | |
| RU2019142795A (ru) | Производное n-(азаарил)циклолактам-1-карбоксамида, метод его получения и его применение | |
| JP2013535491A5 (enExample) | ||
| JP2014520898A5 (enExample) | ||
| JP2013537203A5 (enExample) | ||
| JP2019524883A5 (enExample) | ||
| RU2018138828A (ru) | Уменьшение массы опухоли путем введения ccr1 антагонистов в комбинации с pd-1 ингибиторами или pd-l1 ингибиторами | |
| JP2009263394A5 (enExample) | ||
| CN106660974A (zh) | 含氨磺酰基的1,2,5‑噁二唑类衍生物、其制备方法及其在医药上的应用 | |
| JP2016513660A5 (enExample) | ||
| JP2012153722A5 (enExample) | ||
| JP2015531747A5 (enExample) | ||
| JP2013502441A5 (enExample) | ||
| RU2016143333A (ru) | Амидные производные и их фармацевтически приемлемые соли, способ их получения и медицинское применение | |
| ME02838B (me) | 3,4-dihidroizokinolin-2(1h)-ilni spojevi | |
| JP2013525458A5 (enExample) | ||
| JP2013509431A5 (enExample) | ||
| JP2017502940A5 (enExample) | ||
| JP2017508782A5 (enExample) | ||
| RU2017104856A (ru) | Функционализированные и замещенные индолы в качестве противораковых средств | |
| JP2015511232A5 (enExample) |