JP2015142720A5 - - Google Patents
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- Publication number
- JP2015142720A5 JP2015142720A5 JP2014225283A JP2014225283A JP2015142720A5 JP 2015142720 A5 JP2015142720 A5 JP 2015142720A5 JP 2014225283 A JP2014225283 A JP 2014225283A JP 2014225283 A JP2014225283 A JP 2014225283A JP 2015142720 A5 JP2015142720 A5 JP 2015142720A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- self
- hemostatic material
- gel
- material according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000002439 hemostatic effect Effects 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 8
- 150000003839 salts Chemical class 0.000 claims description 8
- 239000002253 acid Substances 0.000 claims description 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 8
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 238000001338 self-assembly Methods 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- 238000002834 transmittance Methods 0.000 claims 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical class Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical class OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 238000010494 dissociation reaction Methods 0.000 description 1
- 230000005593 dissociations Effects 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014225283A JP2015142720A (ja) | 2013-12-27 | 2014-11-05 | 止血材 |
| PCT/JP2014/082653 WO2015098515A1 (ja) | 2013-12-27 | 2014-12-10 | 止血材 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013271430 | 2013-12-27 | ||
| JP2013271430 | 2013-12-27 | ||
| JP2014225283A JP2015142720A (ja) | 2013-12-27 | 2014-11-05 | 止血材 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015142720A JP2015142720A (ja) | 2015-08-06 |
| JP2015142720A5 true JP2015142720A5 (enExample) | 2016-06-16 |
Family
ID=53478379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014225283A Pending JP2015142720A (ja) | 2013-12-27 | 2014-11-05 | 止血材 |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP2015142720A (enExample) |
| WO (1) | WO2015098515A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015288635B2 (en) * | 2014-07-11 | 2018-07-26 | Menicon Co., Ltd. | Visibility-ensuring material, and device for discharging visibility-ensuring material |
| US11298397B2 (en) | 2015-12-18 | 2022-04-12 | 3-D Matrix, Ltd. | Hemostatic composition and hemostatic method using hemostatic composition |
| KR102647642B1 (ko) * | 2021-05-04 | 2024-03-15 | (주)케어젠 | 혈액 응고 활성을 갖는 펩타이드와 이의 용도 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9327010B2 (en) * | 2005-04-25 | 2016-05-03 | Massachusetts Institute Of Technology | Compositions and methods for promoting hemostasis and other physiological activities |
| US8299032B2 (en) * | 2005-06-27 | 2012-10-30 | Menicon Co., Ltd. | Self-assembling peptide and gel produced from the same |
| EP2345433B1 (en) * | 2008-10-06 | 2017-03-01 | 3-D Matrix, Ltd. | Tissue plug |
| JP6084352B2 (ja) * | 2010-12-24 | 2017-02-22 | 国立大学法人 岡山大学 | 高強度ペプチドゲル |
-
2014
- 2014-11-05 JP JP2014225283A patent/JP2015142720A/ja active Pending
- 2014-12-10 WO PCT/JP2014/082653 patent/WO2015098515A1/ja not_active Ceased
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