JP2015081254A - Cosmetic composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a cosmetic composition preventing putrefaction and microbial contamination without containing an antiseptic agent.SOLUTION: By containing the following (A) to (D): (A) an extract obtained by removing an essential oil component from an extract extracted with a lower alcohol and/or water from a Syzygium aromaticum (Myrtaceae, a flower bud of Syzygium aromaticum) or an extract extracted with a lower alcohol and/or water from Syzygium aromaticum with an essential oil component being beforehand removed; (B) an extract extracted with lower alcohol and/or water from Artemisia capillaris (Asteraceae, a capitulum of Artemisia capillaris); (C) a monoglyceride of an aliphatic acid having a carbon number of 8 to 12; and (D) phenoxyethanol, a cosmetic composition can be given excellent antibacterial and antifungal properties.

Description

  The present invention provides a cosmetic composition that prevents spoilage and microbial contamination without compounding paraoxybenzoates (parabens).

  Cosmetics are composed of water, oils, surfactants, moisturizers, thickeners, plant extracts, and the like, and are often environments in which microorganisms are likely to grow. Therefore, the addition of preservatives is important in ensuring the quality of cosmetics. Parabens are widely used as preservatives, but some users called “sensitive skin” may have irritation and allergic reactions, and cosmetics that do not contain parabens are required. ing.

  In response to the above problems, as described in Non-Patent Document 1, cosmetics using phenoxyethanol as an alternative to parabens have been increasing in recent years. However, phenoxyethanol has low antibacterial properties against microorganisms, and the blending amount must be increased to impart high antibacterial properties. However, when the blending amount of phenoxyethanol is increased, a odor peculiar to phenoxyethanol appears, and it is necessary to mask using a fragrance or the like. In recent years, due to an increase in demand for unscented cosmetics, it is not possible to increase the amount of phenoxyethanol that emits a characteristic odor.

Cosmetic medicine Science of preservatives and fungicides p. 63-88

  An object of the present invention is to provide a cosmetic composition that prevents rot and microbial contamination by not containing parabens and further suppressing the amount of phenoxyethanol to a specific odor.

  As a result of diligent research to solve the above-mentioned problems, the present inventors have found that a wide variety of bacterial species can be obtained by using phenoxyethanol in combination with a clove extract obtained by removing an essential oil component, an extract of Kawamomogi, and a monoglyceride of a fatty acid having 8 to 12 carbon atoms. As a result, the antibacterial action is synergistically improved, and the effect of preventing spoilage and microbial contamination is enhanced against cosmetics, and the present invention has been completed.

  That is, in the present invention, the extract obtained by removing the essential oil component from the extract obtained by extracting (A) clove (Aceraceae, cinnamon flower bud) with a lower alcohol and / or water with respect to the cosmetic, or the essential oil component previously removed An extract obtained by extracting clove from lower alcohol and / or water (B) An extract obtained by extracting pearl millet (Asteraceae, head flower of pearl millet) with lower alcohol and / or water (C) Monoglyceride of fatty acid having 8 to 12 carbon atoms (D) A cosmetic composition containing (A) to (D) of phenoxyethanol.

  According to the present invention, a composition having excellent antibacterial and antifungal properties that can prevent the decay of cosmetics and can be applied in a wide range of fields can be obtained.

  Hereinafter, the present invention will be described in detail based on embodiments.

The clove used in the present invention is referred to as a clove, and is a flower bud of Euphoria caryophyllata (scientific name: Eugenia caryophyllata ), which is used as a spice or a stomach medicine, and can be easily obtained. In order to obtain the clove extract used in the present invention, it may contain leaves and stems in addition to florets, but it is desirable to use only florets.

  As an extraction solvent for obtaining a clove extract, one or more selected from lower alcohols such as methyl alcohol, ethyl alcohol, isopropyl alcohol and water can be used, and the concentration of ethyl alcohol is 50% by weight. The above-mentioned ethyl alcohol aqueous solution and / or methyl alcohol aqueous solution having a methyl alcohol concentration of 50% by weight or more is preferred, and an ethyl alcohol aqueous solution having an ethyl alcohol concentration of 70 to 90% by weight is particularly preferred. Antibacterial components are also extracted when using an ethyl alcohol aqueous solution or an aqueous methyl alcohol solution with an alcohol concentration of less than 50% by weight, but because many pigment components that are hardly involved in antibacterial properties are extracted, the color of the extract itself becomes dark, The appearance of the cosmetic to be added may be impaired, which is not preferable. In particular, it is particularly preferable to use an aqueous ethyl alcohol solution having an ethyl alcohol concentration of 70 to 90% by weight because there is little extraction of the pigment component.

  The amount of the extraction solvent is not particularly limited, but is 20 to 20 times, preferably 5 to 5 times the weight of clove. Extraction is preferably performed at room temperature or low temperature because the extraction of the pigment component can be suppressed. However, the extraction may be performed by heating in order to improve extraction efficiency or shorten the extraction time.

  The clove extract used in the present invention needs to remove essential oil components such as eugenol. Essential oil components such as eugenol have an antibacterial action, but are volatile and have a unique strong odor. Therefore, containing the essential oil component is not preferable because it impairs the scent of cosmetics to be added. Examples of methods for removing essential oil components such as eugenol include a method of removing by steam distillation before extraction of clove, a method of removing water by adding water or blowing water vapor and azeotropically with water after extraction, etc. Any method may be used.

  The thus obtained clove extract from which the essential oil component has been removed may be used as it is, concentrated or used after being completely or properly concentrated and dissolved in a solvent. The solvent that dissolves after the concentration is not particularly limited, but is preferably one commonly used in cosmetics, such as water, ethyl alcohol, isopropyl alcohol, glycerin, propylene glycol, 1,3-butylene glycol. Etc. can be illustrated.

  The clove extract from which these essential oil components have been removed, the concentrate obtained by concentrating the extract, or the extract dissolved in the solvent after the concentration may be added to the cosmetic composition as it is. Since an insoluble component is precipitated or separated, it is preferable to use it after removing a component insoluble in water. The removal of the water-insoluble component can be performed by filtration or the like after adding water to the extract or concentrate to dissolve the water-soluble component. The step of removing the water-insoluble component may be before or after the step of removing the essential oil component. If the water-insoluble component is removed after removing the essential oil component, it should be concentrated as it is to make a concentrate, or after concentration, dissolved in the above-mentioned solvent to make an extract, and then used in a cosmetic composition. Can do. When removing the essential oil component after removing the water-insoluble component, after removing the essential oil component, after concentrating it into a concentrate, or after concentrating, dissolving in the above solvent to obtain an extract, It can be used in cosmetic compositions.

  The amount of the clove extract thus obtained is not particularly limited with respect to the cosmetic composition, but preferably 0.0002 to 0.1 in terms of solid content in consideration of color, odor and antibacterial properties. Mix by weight.

The extract of the silkworm of the present invention can be extracted from the above-ground part of the Asteraceae capillaries (Scientific name: Artemisia capillaries Thumb.) Used as a herbal medicine. In order to obtain the extract of Kawaramugi to be used in the present invention, it may contain leaves and stems, but it is desirable to use only head flowers.

  The wormwood extract is obtained by immersing the wormwood in a solvent and then separating the solvent, and is obtained by distilling off the solvent as necessary. Moreover, it can be obtained by exposing the oleander or its extract to water vapor and recovering essential oil components from the water vapor. Extraction solvents include lower alcohols such as methanol, ethanol and isopropyl alcohol, polyhydric alcohols such as glycerin, propylene glycol and 1,3-butylene glycol, ketones such as acetone and methyl ethyl ketone, hydrocarbons such as hexane, cyclohexane and petroleum ether. And organic solvents such as ethers such as methyl ether, and among these solvents miscible with water, a mixed solvent with water can be used. Although it may be used as it is as long as it is an extraction solution using an extraction solvent that does not interfere with the intended use, it is desirable to use it by completely distilling off the solvent or concentrating it appropriately. At that time, glycerin, 1,3-butylene glycol, propylene glycol, glycerin fatty acid ester, polyglycerin fatty acid ester, sucrose fatty acid ester and the like may be added and concentrated. Moreover, you may use the essential oil component obtained by steam distillation from Kawara mugwort as it is. Furthermore, a solvent extract or an essential oil component obtained by steam distillation may be used after being purified by column chromatography or high performance liquid chromatography.

  The amount of the Kawara mugwort extract thus obtained is not particularly limited with respect to the cosmetic composition, but preferably 0.0002 to 0.2 in terms of solid content in consideration of color, odor, and antibacterial properties. Mix by weight.

  The monoglyceride of a fatty acid having 8 to 12 carbon atoms used in the present invention is a monoester of a fatty acid having 8 to 12 carbon atoms such as caprylic acid, pelargonic acid, capric acid, undecyl acid, undecylenic acid, lauric acid and glycerin. , One or more of these are used. Normally, these monoglycerides are produced by esterifying the above fatty acid and glycerin and separating the monoglyceride by molecular distillation or the like, but even those containing diglyceride or triglyceride can be used. Usually, these monoglycerides are produced by the above-mentioned chemical synthesis, but they are components that exist in nature, and the safety to the human body is superior to the above-mentioned chemical synthetic antibacterial agents. Since these monoglycerides have low solubility in water and precipitate or separate in aqueous cosmetics such as lotion, it is necessary to add a surfactant to the cosmetic composition to solubilize these monoglycerides. However, it is particularly preferable to use caprylic acid monoglyceride because solubilization becomes difficult because the longer the carbon chain length of the fatty acid constituting the monoglyceride, the more the surfactant is required.

  The monoglyceride of a fatty acid having 8 to 12 carbon atoms is blended in an amount of 0.001 to 2% by weight, preferably 0.005 to 1% by weight, based on the cosmetic composition.

  The upper limit of the amount of phenoxyethanol used in the present invention is limited to 1% by weight with respect to the cosmetic, but in view of odor, 0.01 to 0.5% by weight of phenoxyethanol is preferable. In this invention, the compounding quantity of phenoxyethanol can be reduced, it can be safer and antibacterial property can be improved.

  Cosmetic compositions in the present invention are basic cosmetics such as creams, milky lotions, skin lotions, and beauty essences, cosmetics for cleaning such as soaps, facial cleansers, shampoos and rinses, cosmetics for hair such as hair tonics and hair styling, foundations Makeup cosmetics such as eyeliner, mascara and lipstick, oral cosmetics such as toothpaste, and bath cosmetics.

  Examples of the dosage form of the cosmetic composition of the present invention include conventionally known dosage forms such as lotion, bilayer, water-in-oil emulsion, oil-in-water emulsion, gel, mousse, oily, solid, and sheet. Can be used.

  The cosmetic composition of the present invention includes, in addition to the above components, oils, powders (pigments, pigments, resins), fluorine compounds, resins, surfactants, which are usually used in cosmetics, depending on the product form. The purpose of the present invention is to use components such as a thickener, a fragrance, an ultraviolet absorber (organic and inorganic), a moisturizer, a physiologically active ingredient, a salt, a solvent, an antioxidant, a neutralizer, a pH adjuster and an enzyme It can be suitably used within the range that can be achieved.

  EXAMPLES The present invention will be described in more detail with reference to the following examples. However, the present invention is not limited to these examples unless it exceeds the gist.

(Production Example 1 [Preparation of clove extract])
200 g of an ethyl alcohol aqueous solution having an ethyl alcohol concentration of 80% by weight was added to 100 g of dried clove (flower bud) and extracted by immersion for 16 hours at room temperature, followed by vacuum filtration to obtain an extract. The operation of adding 400 g of purified water and concentrating the filtrate obtained by filtering the precipitate under reduced pressure was performed twice to remove the water-insoluble component and azeotropically remove the essential oil component together with water. . 1,3-butylene glycol was added to this concentrate and dissolved to make a total amount of 100 g to obtain a clove extract from which essential oil components were removed. The solid content of this clove extract was 6.2%.

(Production Example 2 [Preparation of Artemisia extract])
500 g of an ethyl alcohol aqueous solution having an ethyl alcohol concentration of 70% by weight was added to 100 g of dried Kawara mugwort (hospital), soaked at room temperature for 16 hours for extraction, and filtered under reduced pressure to obtain an extract. To this, 160 g of 1,3-butylene glycol was added, and then the mixture was concentrated under reduced pressure until the total amount became 200 g, to obtain a wormwood extract. The solid content of this extract was 3.8%.

(Examples 1-4, Comparative Examples 1-6)
Skin lotions of Examples 1 and 2 and Comparative Examples 1, 2 and 3 listed in Table 2 were prepared. Moreover, the emollient creams of Examples 3 and 4 and Comparative Examples 4, 5, and 6 shown in Table 3 were prepared. In addition, all the compounding quantities in these tables | surfaces are shown by weight%.

(Antiseptic test)
Table 3 skin lotions and described, for emollient cream according to Table 5, Pseudomonas aeruginosa (Pseudomonas aeruginosa ATCC 9027), Staphylococcus aureus (Staphylococcus aureus ATCC 6538), Escherichia coli (Escherichia coli ATCC 8739), Candida yeast (Candida albicans ATCC 10231) and Aspergillus niger ATCC 16404) were tested for preservative power. The test was carried out by inoculating 10 6 cells of bacteria and 10 5 cells of fungi per 1 g of the prepared test solution, storing at 25 ° C., and measuring the number of viable bacteria immediately after inoculation and on the 14th day. It was evaluated according to the criteria. The results of the antiseptic test are shown in Tables 3 and 5.

(Odor evaluation)
Odor evaluation was performed on the skin lotion described in Table 3 and the emollient cream described in Table 5. The odor of phenoxyethanol when 2 mL each was applied to the back of the hand was evaluated according to the criteria described in Table 2 by a total of 42 men (age 26-48 years), including 23 male panelists and 19 female panelists. The results are shown in Tables 4 and 6.

  As is apparent from the results in Tables 3 and 4, Comparative Example 1 has a weak antibacterial property against mold and a strong odor characteristic to phenoxyethanol. In Comparative Example 2, although the odor is reduced by reducing the amount of phenoxyethanol, the antibacterial property is also weakened. In Comparative Example 3, since phenoxyethanol is not blended, the odor is greatly suppressed, but the antibacterial properties are weak against some bacteria. On the other hand, in Example 1 which mix | blended phenoxyethanol, the clove extract, Kawara mugwort extract, and the fatty-acid monoglyceride, antibacterial property is synergistically high. Moreover, even in the combination according to the blending ratio of Example 2, high antibacterial properties were exhibited, and further, odor reduction was observed in both Examples 1 and 2 compared to Comparative Example 1.

  Similarly, as is clear from the results of Tables 5 and 6, Comparative Example 4 has a weak antibacterial property against mold and a strong odor. In Comparative Example 5, although the odor is suppressed by reducing the amount of phenoxyethanol, the antibacterial property is also weakened. Moreover, although the odor is also suppressed significantly in Comparative Example 6, the antibacterial property is weak against some bacteria. On the other hand, the antibacterial property is synergistically increased in Example 3 in which phenoxyethanol, clove extract, kawara mugi extract, and fatty acid monoglyceride are blended. Moreover, the combination by the mixture ratio of Example 4 also showed high antibacterial property, and furthermore, in Examples 3 and 4 compared to Comparative Example 4, reduction in odor was recognized.

  ADVANTAGE OF THE INVENTION According to this invention, the cosmetic composition which prevents decay and microbial contamination can be provided, without mix | blending a paraben with a cosmetic composition. Moreover, since the usage-amount of phenoxyethanol can be reduced, the cosmetic composition which reduced the odor of phenoxyethanol and the concern about a irritation feeling can be provided.

Claims (2)

The following (A) to (D):
(A) An extract obtained by extracting clove (Coleoptera: Chrysanthemum flower) with lower alcohol and / or water (B) C) Monoglyceride of a fatty acid having 8 to 12 carbon atoms (D) A cosmetic composition comprising phenoxyethanol. (A) is an extract obtained by removing essential oil components from an extract obtained by extracting clove (Firaceae, Cistaceae flower buds) with lower alcohol and / or water, or clove having previously removed essential oil components with lower alcohol and / or water. The cosmetic composition according to claim 1, wherein the cosmetic composition is an extracted extract.