JP2014533702A5 - - Google Patents
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- Publication number
- JP2014533702A5 JP2014533702A5 JP2014542643A JP2014542643A JP2014533702A5 JP 2014533702 A5 JP2014533702 A5 JP 2014533702A5 JP 2014542643 A JP2014542643 A JP 2014542643A JP 2014542643 A JP2014542643 A JP 2014542643A JP 2014533702 A5 JP2014533702 A5 JP 2014533702A5
- Authority
- JP
- Japan
- Prior art keywords
- inulin
- pharmaceutical composition
- formulation
- sulfonylurea
- sulfonamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920001202 Inulin Polymers 0.000 claims 20
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 claims 20
- 229940029339 inulin Drugs 0.000 claims 20
- 239000000203 mixture Substances 0.000 claims 19
- 238000009472 formulation Methods 0.000 claims 18
- 239000008194 pharmaceutical composition Substances 0.000 claims 17
- 229940100389 Sulfonylurea Drugs 0.000 claims 16
- 229940124530 sulfonamide Drugs 0.000 claims 16
- 150000003456 sulfonamides Chemical class 0.000 claims 16
- 239000002207 metabolite Substances 0.000 claims 14
- YROXIXLRRCOBKF-UHFFFAOYSA-N sulfonylurea Chemical class OC(=N)N=S(=O)=O YROXIXLRRCOBKF-UHFFFAOYSA-N 0.000 claims 14
- 238000006116 polymerization reaction Methods 0.000 claims 9
- 239000002552 dosage form Substances 0.000 claims 8
- 206010012601 diabetes mellitus Diseases 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 3
- BOVGTQGAOIONJV-BETUJISGSA-N 1-[(3ar,6as)-3,3a,4,5,6,6a-hexahydro-1h-cyclopenta[c]pyrrol-2-yl]-3-(4-methylphenyl)sulfonylurea Chemical compound C1=CC(C)=CC=C1S(=O)(=O)NC(=O)NN1C[C@H]2CCC[C@H]2C1 BOVGTQGAOIONJV-BETUJISGSA-N 0.000 claims 2
- RKWGIWYCVPQPMF-UHFFFAOYSA-N Chloropropamide Chemical compound CCCNC(=O)NS(=O)(=O)C1=CC=C(Cl)C=C1 RKWGIWYCVPQPMF-UHFFFAOYSA-N 0.000 claims 2
- PJSFRIWCGOHTNF-UHFFFAOYSA-N Sulphormetoxin Chemical compound COC1=NC=NC(NS(=O)(=O)C=2C=CC(N)=CC=2)=C1OC PJSFRIWCGOHTNF-UHFFFAOYSA-N 0.000 claims 2
- JLRGJRBPOGGCBT-UHFFFAOYSA-N Tolbutamide Chemical compound CCCCNC(=O)NS(=O)(=O)C1=CC=C(C)C=C1 JLRGJRBPOGGCBT-UHFFFAOYSA-N 0.000 claims 2
- 229960001466 acetohexamide Drugs 0.000 claims 2
- VGZSUPCWNCWDAN-UHFFFAOYSA-N acetohexamide Chemical compound C1=CC(C(=O)C)=CC=C1S(=O)(=O)NC(=O)NC1CCCCC1 VGZSUPCWNCWDAN-UHFFFAOYSA-N 0.000 claims 2
- 229960003362 carbutamide Drugs 0.000 claims 2
- VDTNNGKXZGSZIP-UHFFFAOYSA-N carbutamide Chemical compound CCCCNC(=O)NS(=O)(=O)C1=CC=C(N)C=C1 VDTNNGKXZGSZIP-UHFFFAOYSA-N 0.000 claims 2
- 229960001761 chlorpropamide Drugs 0.000 claims 2
- GJQPMPFPNINLKP-UHFFFAOYSA-N diclofenamide Chemical compound NS(=O)(=O)C1=CC(Cl)=C(Cl)C(S(N)(=O)=O)=C1 GJQPMPFPNINLKP-UHFFFAOYSA-N 0.000 claims 2
- IAVUPMFITXYVAF-XPUUQOCRSA-N dorzolamide Chemical compound CCN[C@H]1C[C@H](C)S(=O)(=O)C2=C1C=C(S(N)(=O)=O)S2 IAVUPMFITXYVAF-XPUUQOCRSA-N 0.000 claims 2
- 229960003933 dorzolamide Drugs 0.000 claims 2
- BJHIKXHVCXFQLS-UYFOZJQFSA-N fructose group Chemical group OCC(=O)[C@@H](O)[C@H](O)[C@H](O)CO BJHIKXHVCXFQLS-UYFOZJQFSA-N 0.000 claims 2
- 229960004580 glibenclamide Drugs 0.000 claims 2
- 229960001764 glibornuride Drugs 0.000 claims 2
- RMTYNAPTNBJHQI-LLDVTBCESA-N glibornuride Chemical compound C1=CC(C)=CC=C1S(=O)(=O)NC(=O)N[C@H]1[C@H](C2(C)C)CC[C@@]2(C)[C@H]1O RMTYNAPTNBJHQI-LLDVTBCESA-N 0.000 claims 2
- 229960000346 gliclazide Drugs 0.000 claims 2
- 229960004346 glimepiride Drugs 0.000 claims 2
- WIGIZIANZCJQQY-RUCARUNLSA-N glimepiride Chemical compound O=C1C(CC)=C(C)CN1C(=O)NCCC1=CC=C(S(=O)(=O)NC(=O)N[C@@H]2CC[C@@H](C)CC2)C=C1 WIGIZIANZCJQQY-RUCARUNLSA-N 0.000 claims 2
- 229960001381 glipizide Drugs 0.000 claims 2
- ZJJXGWJIGJFDTL-UHFFFAOYSA-N glipizide Chemical compound C1=NC(C)=CN=C1C(=O)NCCC1=CC=C(S(=O)(=O)NC(=O)NC2CCCCC2)C=C1 ZJJXGWJIGJFDTL-UHFFFAOYSA-N 0.000 claims 2
- ZNNLBTZKUZBEKO-UHFFFAOYSA-N glyburide Chemical compound COC1=CC=C(Cl)C=C1C(=O)NCCC1=CC=C(S(=O)(=O)NC(=O)NC2CCCCC2)C=C1 ZNNLBTZKUZBEKO-UHFFFAOYSA-N 0.000 claims 2
- -1 glycoxepide Chemical compound 0.000 claims 2
- 229960005125 metahexamide Drugs 0.000 claims 2
- XXYTXQGCRQLRHA-UHFFFAOYSA-N metahexamide Chemical compound C1=C(N)C(C)=CC=C1S(=O)(=O)NC(=O)NC1CCCCC1 XXYTXQGCRQLRHA-UHFFFAOYSA-N 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- SKIVFJLNDNKQPD-UHFFFAOYSA-N sulfacetamide Chemical compound CC(=O)NS(=O)(=O)C1=CC=C(N)C=C1 SKIVFJLNDNKQPD-UHFFFAOYSA-N 0.000 claims 2
- 229960002673 sulfacetamide Drugs 0.000 claims 2
- 229960004673 sulfadoxine Drugs 0.000 claims 2
- 229960005404 sulfamethoxazole Drugs 0.000 claims 2
- YZMCKZRAOLZXAZ-UHFFFAOYSA-N sulfisomidine Chemical compound CC1=NC(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 YZMCKZRAOLZXAZ-UHFFFAOYSA-N 0.000 claims 2
- 229960001975 sulfisomidine Drugs 0.000 claims 2
- JLKIGFTWXXRPMT-UHFFFAOYSA-N sulphamethoxazole Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 JLKIGFTWXXRPMT-UHFFFAOYSA-N 0.000 claims 2
- 229960002277 tolazamide Drugs 0.000 claims 2
- OUDSBRTVNLOZBN-UHFFFAOYSA-N tolazamide Chemical compound C1=CC(C)=CC=C1S(=O)(=O)NC(=O)NN1CCCCCC1 OUDSBRTVNLOZBN-UHFFFAOYSA-N 0.000 claims 2
- 229960005371 tolbutamide Drugs 0.000 claims 2
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 208000024172 Cardiovascular disease Diseases 0.000 claims 1
- 206010012374 Depressed mood Diseases 0.000 claims 1
- 208000020564 Eye injury Diseases 0.000 claims 1
- 208000017899 Foot injury Diseases 0.000 claims 1
- 208000018522 Gastrointestinal disease Diseases 0.000 claims 1
- 208000013016 Hypoglycemia Diseases 0.000 claims 1
- 206010061225 Limb injury Diseases 0.000 claims 1
- 208000028389 Nerve injury Diseases 0.000 claims 1
- 206010061481 Renal injury Diseases 0.000 claims 1
- 208000021017 Weight Gain Diseases 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 206010016256 fatigue Diseases 0.000 claims 1
- 201000001421 hyperglycemia Diseases 0.000 claims 1
- 230000002218 hypoglycaemic effect Effects 0.000 claims 1
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 1
- 208000037806 kidney injury Diseases 0.000 claims 1
- 239000011707 mineral Substances 0.000 claims 1
- 230000008764 nerve damage Effects 0.000 claims 1
- 230000000069 prophylactic effect Effects 0.000 claims 1
- 230000036186 satiety Effects 0.000 claims 1
- 235000019627 satiety Nutrition 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 1
- 230000004584 weight gain Effects 0.000 claims 1
- 235000019786 weight gain Nutrition 0.000 claims 1
- 230000004580 weight loss Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2011904887 | 2011-11-23 | ||
| AU2011904887A AU2011904887A0 (en) | 2011-11-23 | Improved synergistic anti-diabetic compositions | |
| AU2012902723 | 2012-06-27 | ||
| AU2012902723A AU2012902723A0 (en) | 2012-06-27 | Improved synergistic anti-diabetic compositions -II | |
| PCT/AU2012/001442 WO2013075172A1 (en) | 2011-11-23 | 2012-11-23 | Improved synergistic anti-diabetic compositions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017133685A Division JP6609287B2 (ja) | 2011-11-23 | 2017-07-07 | 改良された相乗作用を示す抗糖尿病、抗高血糖症又は抗副作用のための医薬組成物及び製剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014533702A JP2014533702A (ja) | 2014-12-15 |
| JP2014533702A5 true JP2014533702A5 (enExample) | 2016-01-21 |
Family
ID=48468910
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014542643A Pending JP2014533702A (ja) | 2011-11-23 | 2012-11-23 | 改良された相乗作用抗糖尿病組成物 |
| JP2017133685A Active JP6609287B2 (ja) | 2011-11-23 | 2017-07-07 | 改良された相乗作用を示す抗糖尿病、抗高血糖症又は抗副作用のための医薬組成物及び製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017133685A Active JP6609287B2 (ja) | 2011-11-23 | 2017-07-07 | 改良された相乗作用を示す抗糖尿病、抗高血糖症又は抗副作用のための医薬組成物及び製剤 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9737559B2 (enExample) |
| EP (1) | EP2782586A4 (enExample) |
| JP (2) | JP2014533702A (enExample) |
| KR (1) | KR102104384B1 (enExample) |
| CN (1) | CN104244958B (enExample) |
| AU (1) | AU2012343332B2 (enExample) |
| BR (1) | BR112014012401A2 (enExample) |
| CA (1) | CA2861661C (enExample) |
| IN (1) | IN2014KN01304A (enExample) |
| RU (1) | RU2642633C2 (enExample) |
| WO (1) | WO2013075172A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109498611B (zh) * | 2019-01-15 | 2020-09-01 | 张惊宇 | 一种治疗糖尿病周围神经痛的药物及其用途 |
| RU2741079C1 (ru) * | 2020-04-06 | 2021-01-22 | Общество С Ограниченной Ответственностью "Технологии Дкв" | Пищевая добавка «пребио дкв» |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4082842A (en) * | 1975-02-21 | 1978-04-04 | Armando Nahle | Medicant composition for the treatment of diabetes |
| US5859037A (en) | 1997-02-19 | 1999-01-12 | Warner-Lambert Company | Sulfonylurea-glitazone combinations for diabetes |
| EP1310173B2 (en) * | 1997-06-23 | 2014-12-31 | Société des Produits Nestlé S.A. | Composition for providing nutrition to diabetics |
| US20030130205A1 (en) * | 2000-04-12 | 2003-07-10 | Christian Samuel T. | Novel pharmaceutical anti-infective agents containing carbohydrate moieties and methods of their preparation and use |
| US6689385B2 (en) * | 2000-11-03 | 2004-02-10 | Chronorx Llc | Formulations for the treatment of insulin resistance and type 2 diabetes mellitus |
| WO2004070009A2 (en) * | 2003-01-31 | 2004-08-19 | Targesome Inc. | Targeted multivalent macromolecules |
| US20070004623A1 (en) | 2003-10-27 | 2007-01-04 | Innodia Inc. | Use of hydroxylated amino acids for treating diabetes |
| JP2006052191A (ja) * | 2004-08-16 | 2006-02-23 | Taiyo Kagaku Co Ltd | 糖尿病予防、改善、または治療用組成物 |
| CN1861173A (zh) | 2005-05-13 | 2006-11-15 | 王锦 | 糖尿病人营养治疗药品膳食纤维素粉产品 |
| EP1893041A4 (en) * | 2005-06-17 | 2009-05-13 | Henry H Ottens Mfg Company Inc | FIBER-REINFORCED CEREALS, CEREAL BARS AND FOODS AND METHODS OF MAKING |
| EP1832179B1 (en) * | 2005-12-20 | 2018-11-07 | N.V. Nutricia | Carbohydrate composition and flat glucose response |
| EP2146680B1 (en) * | 2007-05-10 | 2011-10-19 | L'Oréal | Cosmetic composition comprising an inulin derivative in the form of an emulsion expanded in volume |
| US20090214511A1 (en) * | 2008-02-21 | 2009-08-27 | Trung Hong Tran | Digestible compositions of inulin for managing blood glucose levels |
| GB0907019D0 (en) * | 2009-04-24 | 2009-06-03 | Oxford Nutrascience Ltd | Pharmaceutical,therapeutic or nutritional delivery systems for functional ingredients |
| KR20120015335A (ko) * | 2009-05-01 | 2012-02-21 | 마이크로파마 리미티드 | 퇴행성 질환의 예방 및 치료를 위한 박테리아 조성물 |
| AU2011257964B2 (en) * | 2010-05-24 | 2014-10-30 | Ozstar Therapeutics Pty Ltd | Anti-diabetic compositions and methods |
-
2012
- 2012-11-23 JP JP2014542643A patent/JP2014533702A/ja active Pending
- 2012-11-23 WO PCT/AU2012/001442 patent/WO2013075172A1/en not_active Ceased
- 2012-11-23 US US14/359,759 patent/US9737559B2/en active Active
- 2012-11-23 KR KR1020147017070A patent/KR102104384B1/ko active Active
- 2012-11-23 CN CN201280067463.9A patent/CN104244958B/zh active Active
- 2012-11-23 EP EP12851708.3A patent/EP2782586A4/en not_active Ceased
- 2012-11-23 AU AU2012343332A patent/AU2012343332B2/en active Active
- 2012-11-23 CA CA2861661A patent/CA2861661C/en active Active
- 2012-11-23 BR BR112014012401A patent/BR112014012401A2/pt not_active Application Discontinuation
- 2012-11-23 RU RU2014125249A patent/RU2642633C2/ru active
-
2014
- 2014-06-19 IN IN1304/KOLNP/2014A patent/IN2014KN01304A/en unknown
-
2017
- 2017-07-07 JP JP2017133685A patent/JP6609287B2/ja active Active
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