JP2014533102A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014533102A5 JP2014533102A5 JP2014539995A JP2014539995A JP2014533102A5 JP 2014533102 A5 JP2014533102 A5 JP 2014533102A5 JP 2014539995 A JP2014539995 A JP 2014539995A JP 2014539995 A JP2014539995 A JP 2014539995A JP 2014533102 A5 JP2014533102 A5 JP 2014533102A5
- Authority
- JP
- Japan
- Prior art keywords
- clonotype
- segment
- patient
- pharmaceutical composition
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161556125P | 2011-11-04 | 2011-11-04 | |
| US61/556,125 | 2011-11-04 | ||
| US201161561234P | 2011-11-17 | 2011-11-17 | |
| US61/561,234 | 2011-11-17 | ||
| PCT/US2012/061977 WO2013066726A1 (en) | 2011-11-04 | 2012-10-25 | T-cell receptor clonotypes shared among ankylosing spondylitis patients |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014533102A JP2014533102A (ja) | 2014-12-11 |
| JP2014533102A5 true JP2014533102A5 (enExample) | 2015-12-10 |
| JP6130387B2 JP6130387B2 (ja) | 2017-05-17 |
Family
ID=48192637
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014539995A Active JP6130387B2 (ja) | 2011-11-04 | 2012-10-25 | 強直性脊椎炎の患者間で共有されるｔ細胞受容体クロノタイプ |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20150252422A1 (enExample) |
| EP (1) | EP2773773B1 (enExample) |
| JP (1) | JP6130387B2 (enExample) |
| ES (1) | ES2619713T3 (enExample) |
| WO (1) | WO2013066726A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9394567B2 (en) | 2008-11-07 | 2016-07-19 | Adaptive Biotechnologies Corporation | Detection and quantification of sample contamination in immune repertoire analysis |
| US8748103B2 (en) | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| US8628927B2 (en) | 2008-11-07 | 2014-01-14 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| EP2719774B8 (en) | 2008-11-07 | 2020-04-22 | Adaptive Biotechnologies Corporation | Methods of monitoring conditions by sequence analysis |
| US9528160B2 (en) | 2008-11-07 | 2016-12-27 | Adaptive Biotechnolgies Corp. | Rare clonotypes and uses thereof |
| US9365901B2 (en) | 2008-11-07 | 2016-06-14 | Adaptive Biotechnologies Corp. | Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia |
| US9506119B2 (en) | 2008-11-07 | 2016-11-29 | Adaptive Biotechnologies Corp. | Method of sequence determination using sequence tags |
| HUE029424T2 (en) | 2009-01-15 | 2017-02-28 | Adaptive Biotechnologies Corp | Adaptive immunity profiling and a method for producing monoclonal antibodies |
| RU2539032C2 (ru) | 2009-06-25 | 2015-01-10 | Фред Хатчинсон Кансэр Рисёч Сентер | Способ измерения искусственного иммунитета |
| US9043160B1 (en) | 2009-11-09 | 2015-05-26 | Sequenta, Inc. | Method of determining clonotypes and clonotype profiles |
| US10385475B2 (en) | 2011-09-12 | 2019-08-20 | Adaptive Biotechnologies Corp. | Random array sequencing of low-complexity libraries |
| AU2012325791B2 (en) | 2011-10-21 | 2018-04-05 | Adaptive Biotechnologies Corporation | Quantification of adaptive immune cell genomes in a complex mixture of cells |
| ES2867924T3 (es) | 2011-12-09 | 2021-10-21 | Adaptive Biotechnologies Corp | Diagnóstico de tumores malignos linfoides y detección de enfermedad residual mínima |
| US9499865B2 (en) | 2011-12-13 | 2016-11-22 | Adaptive Biotechnologies Corp. | Detection and measurement of tissue-infiltrating lymphocytes |
| EP2823060B1 (en) | 2012-03-05 | 2018-02-14 | Adaptive Biotechnologies Corporation | Determining paired immune receptor chains from frequency matched subunits |
| DK2831276T3 (da) | 2012-05-08 | 2016-08-01 | Adaptive Biotechnologies Corp | Sammensætninger og fremgangsmåde til at måle og kalibrere amplifikations-bias i multipleks-PCR-reaktioner |
| US20160002731A1 (en) | 2012-10-01 | 2016-01-07 | Adaptive Biotechnologies Corporation | Immunocompetence assessment by adaptive immune receptor diversity and clonality characterization |
| US9708657B2 (en) * | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
| AU2015227054A1 (en) | 2014-03-05 | 2016-09-22 | Adaptive Biotechnologies Corporation | Methods using randomer-containing synthetic molecules |
| US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
| EP3132059B1 (en) | 2014-04-17 | 2020-01-08 | Adaptive Biotechnologies Corporation | Quantification of adaptive immune cell genomes in a complex mixture of cells |
| CA2966201A1 (en) | 2014-10-29 | 2016-05-06 | Adaptive Biotechnologies Corp. | Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples |
| US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
| AU2015353581A1 (en) | 2014-11-25 | 2017-06-15 | Adaptive Biotechnologies Corporation | Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing |
| ES2858306T3 (es) | 2015-02-24 | 2021-09-30 | Adaptive Biotechnologies Corp | Método para determinar el estado de HLA mediante secuenciación del repertorio inmunitario |
| EP3277294B1 (en) | 2015-04-01 | 2024-05-15 | Adaptive Biotechnologies Corp. | Method of identifying human compatible t cell receptors specific for an antigenic target |
| CN107345240A (zh) * | 2016-05-12 | 2017-11-14 | 眭维国 | T细胞抗原受体β链CDR3的处理方法 |
| US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
| US11254980B1 (en) | 2017-11-29 | 2022-02-22 | Adaptive Biotechnologies Corporation | Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5667967A (en) * | 1990-05-01 | 1997-09-16 | The Board Of Trustees Of The Leland Stanford Junior University | T-cell receptor varible transcripts as disease related markers |
| AU736742B2 (en) * | 1996-06-03 | 2001-08-02 | Governors Of The University Of Alberta, The | Methods for detection of rearranged DNA |
| CA2626804A1 (en) * | 2005-11-01 | 2007-08-09 | Abbott Biotechnology Ltd. | Methods and compositions for diagnosing ankylosing spondylitis using biomarkers |
| ES2261104B1 (es) * | 2006-06-19 | 2007-06-16 | Grifols, S.A. | "tapon para frascos de productos esteriles y utilizacion de dicho tapon en la dosificacion esteril". |
| US8748103B2 (en) * | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| KR20110110247A (ko) * | 2008-12-30 | 2011-10-06 | 센토코 오르토 바이오테크 인코포레이티드 | 강직성 척추염 환자에서 항-ＴＮＦα 항체에 대한 임상적 반응을 예측하는 혈청 마커 |
| KR101323827B1 (ko) * | 2010-01-08 | 2013-10-31 | 키스트 유럽 에프게엠베하 | 강직성척추염 진단용 프라이머 및 이를 이용한 강직성 척추염 진단 방법 |
-
2012
- 2012-10-25 ES ES12844825.5T patent/ES2619713T3/es active Active
- 2012-10-25 JP JP2014539995A patent/JP6130387B2/ja active Active
- 2012-10-25 US US14/350,785 patent/US20150252422A1/en not_active Abandoned
- 2012-10-25 EP EP12844825.5A patent/EP2773773B1/en active Active
- 2012-10-25 WO PCT/US2012/061977 patent/WO2013066726A1/en not_active Ceased
-
2017
- 2017-02-03 US US15/424,550 patent/US20170191132A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2014533102A5 (enExample) | ||
| JP5690588B2 (ja) | 肝細胞癌のサブタイプを決定し、肝癌幹細胞を検出するための方法 | |
| JP2011188853A5 (enExample) | ||
| JP2016519763A5 (enExample) | ||
| JP6755241B2 (ja) | 新規分子バイオマーカーを使用して慢性閉塞性肺疾患（ｃｏｐｄ）を診断する方法 | |
| WO2018195328A1 (en) | Methods of predicting non-response to anti-tnf treatment in subjects with inflammatory bowel disease | |
| Fleming-Canepa et al. | Duck innate immune responses to high and low pathogenicity H5 avian influenza viruses | |
| JP6755240B2 (ja) | 新規分子バイオマーカーを使用して慢性閉塞性肺疾患（ｃｏｐｄ）を診断する方法 | |
| JP6755242B2 (ja) | 新規分子バイオマーカーを使用して慢性閉塞性肺疾患（ｃｏｐｄ）を診断する方法 | |
| JP2015530868A5 (enExample) | ||
| JP2019518063A5 (enExample) | ||
| JP2017532961A (ja) | Ｓｍａｄ７アンチセンスオリゴヌクレオチドによる対象を処置するための方法および組成物 | |
| JP2017532961A5 (enExample) | ||
| JP2013518579A5 (enExample) | ||
| JP2018504909A5 (enExample) | ||
| Brandt et al. | Consistent detection of bovine papillomavirus in lesions, intact skin and peripheral blood mononuclear cells of horses affected by hoof canker | |
| AU2019253079A1 (en) | miRNAs for treatment and in vitro diagnosis of drug resistant tumors | |
| US20190249261A1 (en) | Methods For Identifying Clonal Mutations And Treating Cancer | |
| Campos Gudino et al. | Aberrant HMGA2 expression sustains genome instability that promotes metastasis and therapeutic resistance in colorectal cancer | |
| US20220364184A1 (en) | Compositions and methods for treatment of a poor prognosis subtype of colorectal cancer | |
| JP6346493B2 (ja) | ペプチドワクチン療法の効果予測方法 | |
| CN102787163B (zh) | 检测OTOF基因c.1671_1673delG突变的试剂盒 | |
| CN102732613A (zh) | 检测OTOF基因c.5833delG突变的试剂盒 | |
| Iyer et al. | SORT LNPs encapsulating Cas9 mRNA achieve efficient editing in skeletal muscle in a dystrophic mouse model | |
| CN105349632A (zh) | 原发性高血压易感基因Mfn2的基因变异及其检测方法 |