JP2014532758A5 - - Google Patents
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- Publication number
- JP2014532758A5 JP2014532758A5 JP2014541011A JP2014541011A JP2014532758A5 JP 2014532758 A5 JP2014532758 A5 JP 2014532758A5 JP 2014541011 A JP2014541011 A JP 2014541011A JP 2014541011 A JP2014541011 A JP 2014541011A JP 2014532758 A5 JP2014532758 A5 JP 2014532758A5
- Authority
- JP
- Japan
- Prior art keywords
- day
- drug
- dose
- uric acid
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims 25
- 229940079593 drug Drugs 0.000 claims 17
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 claims 13
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 claims 13
- 229940116269 uric acid Drugs 0.000 claims 13
- 239000003795 chemical substances by application Substances 0.000 claims 11
- 229940123769 Xanthine oxidase inhibitor Drugs 0.000 claims 9
- BQSJTQLCZDPROO-UHFFFAOYSA-N febuxostat Chemical group C1=C(C#N)C(OCC(C)C)=CC=C1C1=NC(C)=C(C(O)=O)S1 BQSJTQLCZDPROO-UHFFFAOYSA-N 0.000 claims 9
- 229960005101 febuxostat Drugs 0.000 claims 9
- 229950000958 halofenate Drugs 0.000 claims 9
- 239000003064 xanthine oxidase inhibitor Substances 0.000 claims 9
- 201000005569 Gout Diseases 0.000 claims 5
- 201000001431 Hyperuricemia Diseases 0.000 claims 4
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 claims 3
- 239000002253 acid Substances 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 210000002966 serum Anatomy 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2011/059394 WO2013066349A1 (en) | 2011-11-04 | 2011-11-04 | Methods for treating hyperuricemia in patients with gout using halofenate or halofenic acid and a second urate-lowering agent |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016206043A Division JP6368756B2 (ja) | 2016-10-20 | 2016-10-20 | ハロフェナートまたはハロフェン酸および第２の尿酸低下薬を用いる痛風に罹っている患者の高尿酸血症の治療方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014532758A JP2014532758A (ja) | 2014-12-08 |
| JP2014532758A5 true JP2014532758A5 (enExample) | 2015-01-22 |
| JP6202633B2 JP6202633B2 (ja) | 2017-09-27 |
Family
ID=48192533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014541011A Expired - Fee Related JP6202633B2 (ja) | 2011-11-04 | 2011-11-04 | ハロフェナートまたはハロフェン酸および第２の尿酸低下薬を用いる痛風に罹っている患者の高尿酸血症の治療方法 |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP2773336A4 (enExample) |
| JP (1) | JP6202633B2 (enExample) |
| KR (1) | KR20140121383A (enExample) |
| CN (2) | CN104066427A (enExample) |
| AU (1) | AU2011380507B2 (enExample) |
| CA (1) | CA2859686C (enExample) |
| CL (1) | CL2014001155A1 (enExample) |
| IL (1) | IL232386A0 (enExample) |
| MX (1) | MX357507B (enExample) |
| NZ (1) | NZ624708A (enExample) |
| SG (1) | SG11201402032RA (enExample) |
| WO (1) | WO2013066349A1 (enExample) |
| ZA (1) | ZA201403575B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013245675B2 (en) * | 2012-04-13 | 2017-02-09 | Cymabay Therapeutics, Inc. | Method for treating hyperuricemia in patients with gout using halofenate or halofenic acid and an anti-inflammatory agent |
| TWI809304B (zh) | 2014-12-01 | 2023-07-21 | 奥默羅斯公司 | 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液 |
| JP6368756B2 (ja) * | 2016-10-20 | 2018-08-01 | サイマベイ・セラピューティクス・インコーポレイテッドＣｙｍａＢａｙ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | ハロフェナートまたはハロフェン酸および第２の尿酸低下薬を用いる痛風に罹っている患者の高尿酸血症の治療方法 |
| CN108014108A (zh) * | 2016-11-03 | 2018-05-11 | 江苏万邦生化医药股份有限公司 | lesinurad或其医药上可接受的盐在制备治疗或预防库欣综合征的药物中的应用 |
| JP7086980B2 (ja) * | 2017-10-26 | 2022-06-20 | 大塚製薬株式会社 | イノシトールリン酸含有組成物 |
| WO2021186250A2 (en) * | 2020-03-15 | 2021-09-23 | Allen Davidoff | Methods of treating viral infections and health consequences |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6262118B1 (en) * | 1999-06-04 | 2001-07-17 | Metabolex, Inc. | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia |
| US7576131B2 (en) * | 1999-06-04 | 2009-08-18 | Metabolex, Inc. | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia |
| WO2011032175A1 (en) * | 2009-09-14 | 2011-03-17 | Nuon Therapeutics, Inc. | Combination formulations of tranilast and allopurinol and methods related thereto |
| US9023856B2 (en) * | 2011-11-04 | 2015-05-05 | Cymabay Therapeutics, Inc. | Methods for treating hyperuricemia in patients with gout using halofenate or halogenic acid and a second urate-lowering agent |
-
2011
- 2011-11-04 AU AU2011380507A patent/AU2011380507B2/en not_active Ceased
- 2011-11-04 MX MX2014005400A patent/MX357507B/es active IP Right Grant
- 2011-11-04 CN CN201180076191.4A patent/CN104066427A/zh active Pending
- 2011-11-04 SG SG11201402032RA patent/SG11201402032RA/en unknown
- 2011-11-04 EP EP11875114.8A patent/EP2773336A4/en not_active Withdrawn
- 2011-11-04 NZ NZ624708A patent/NZ624708A/en not_active IP Right Cessation
- 2011-11-04 WO PCT/US2011/059394 patent/WO2013066349A1/en not_active Ceased
- 2011-11-04 CA CA2859686A patent/CA2859686C/en not_active Expired - Fee Related
- 2011-11-04 JP JP2014541011A patent/JP6202633B2/ja not_active Expired - Fee Related
- 2011-11-04 KR KR1020147015169A patent/KR20140121383A/ko not_active Abandoned
- 2011-11-04 CN CN201910004813.0A patent/CN109908124A/zh active Pending
-
2014
- 2014-04-30 IL IL232386A patent/IL232386A0/en unknown
- 2014-05-02 CL CL2014001155A patent/CL2014001155A1/es unknown
- 2014-05-16 ZA ZA2014/03575A patent/ZA201403575B/en unknown
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