JP2014532728A5 - - Google Patents
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- Publication number
- JP2014532728A5 JP2014532728A5 JP2014540197A JP2014540197A JP2014532728A5 JP 2014532728 A5 JP2014532728 A5 JP 2014532728A5 JP 2014540197 A JP2014540197 A JP 2014540197A JP 2014540197 A JP2014540197 A JP 2014540197A JP 2014532728 A5 JP2014532728 A5 JP 2014532728A5
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- hydrogen
- group
- composition
- opioid agonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161556693P | 2011-11-07 | 2011-11-07 | |
| US61/556,693 | 2011-11-07 | ||
| PCT/US2012/063725 WO2013070617A1 (en) | 2011-11-07 | 2012-11-06 | Compositions, dosage forms, and coadministration of an opioid agonist compound and an analgesic compound |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018118989A Division JP2018158940A (ja) | 2011-11-07 | 2018-06-22 | オピオイドアゴニスト化合物と鎮痛性化合物との組成物、剤形、および同時投与 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014532728A JP2014532728A (ja) | 2014-12-08 |
| JP2014532728A5 true JP2014532728A5 (cg-RX-API-DMAC7.html) | 2015-12-10 |
| JP6593993B2 JP6593993B2 (ja) | 2019-10-23 |
Family
ID=47297432
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014540197A Expired - Fee Related JP6593993B2 (ja) | 2011-11-07 | 2012-11-06 | オピオイドアゴニスト化合物と鎮痛性化合物との組成物、剤形、および同時投与 |
| JP2018118989A Withdrawn JP2018158940A (ja) | 2011-11-07 | 2018-06-22 | オピオイドアゴニスト化合物と鎮痛性化合物との組成物、剤形、および同時投与 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018118989A Withdrawn JP2018158940A (ja) | 2011-11-07 | 2018-06-22 | オピオイドアゴニスト化合物と鎮痛性化合物との組成物、剤形、および同時投与 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9457024B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2776046A1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6593993B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102016305B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN103906522B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2012336030B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2854512A1 (cg-RX-API-DMAC7.html) |
| MX (1) | MX348933B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013070617A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10512644B2 (en) * | 2007-03-12 | 2019-12-24 | Inheris Pharmaceuticals, Inc. | Oligomer-opioid agonist conjugates |
| CA2854512A1 (en) * | 2011-11-07 | 2013-05-16 | Nektar Therapeutics | Compositions, dosage forms, and co-administration of an opioid agonist compound and an analgesic compound |
| US10525054B2 (en) * | 2011-11-07 | 2020-01-07 | Inheris Biopharma, Inc. | Compositions, dosage forms, and co-administration of an opioid agonist compound and an analgesic compound |
| CA2919892C (en) | 2013-08-12 | 2019-06-18 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| US9688638B2 (en) | 2013-11-27 | 2017-06-27 | Nektar Therapeutics | Opioid agonists and uses thereof |
| WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| EP3169315B1 (en) | 2014-07-17 | 2020-06-24 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
| AU2015336065A1 (en) | 2014-10-20 | 2017-05-04 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| CN105111136B (zh) * | 2015-09-16 | 2017-07-04 | 上海皓伯化工科技有限公司 | 一种制备3‑甲基‑1‑苯乙基哌啶‑4‑酮或1‑苯乙基哌啶‑4‑酮的方法 |
| CN107033154B (zh) | 2016-02-02 | 2020-02-04 | 上海瀚迈生物医药科技有限公司 | 阿片受体拮抗剂缀合物及其应用 |
| CN117003693A (zh) * | 2022-05-05 | 2023-11-07 | 四川大学华西医院 | 一类哌啶衍生物及其制备方法和用途 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2628962A (en) | 1949-10-20 | 1953-02-17 | Mallinckrodt Chemical Works | Method for preparing dihydrocodeinone, dihydromorphinone, and codeinone |
| US2654756A (en) | 1949-10-20 | 1953-10-06 | Mallinckrodt Chemical Works | Process of preparing codeinone, dihydrocodeinone, and dihydromorphinone |
| US2649454A (en) | 1951-08-20 | 1953-08-18 | Univ California | Method for preparing dihydromorphinone, dihydrocodeinone, and dihydropseudocodeinone |
| US2806033A (en) | 1955-08-03 | 1957-09-10 | Lewenstein | Morphine derivative |
| GB971700A (en) * | 1961-02-02 | 1964-09-30 | Boots Pure Drug Co Ltd | Anti-Inflammatory Agents |
| AU661723B2 (en) * | 1991-10-30 | 1995-08-03 | Mcneilab, Inc. | Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug |
| US5672662A (en) | 1995-07-07 | 1997-09-30 | Shearwater Polymers, Inc. | Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications |
| US5840731A (en) | 1995-08-02 | 1998-11-24 | Virginia Commonwealth University | Pain-alleviating drug composition and method for alleviating pain |
| US6835802B2 (en) | 2001-06-04 | 2004-12-28 | Nobex Corporation | Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties |
| EP1436012B1 (en) * | 2001-10-18 | 2017-12-20 | Nektar Therapeutics | Polymer conjugates of opioid antagonists |
| DE60318041T2 (de) | 2002-05-16 | 2008-11-27 | N.V. Organon | Synergetische Kombination eines Opiatanalgetikums und eines NSAID's |
| KR101168620B1 (ko) | 2003-12-16 | 2012-08-03 | 넥타르 테라퓨틱스 | Ｐｅｇ화된 소분자 |
| AU2007224229B2 (en) * | 2006-03-06 | 2012-10-11 | Pozen Inc. | Dosage forms for administering combinations of drugs |
| CA2661818A1 (en) * | 2006-05-03 | 2007-11-15 | Kowa Pharmaceuticals America, Inc. | Acute pain medications based on fast acting diclofenac-opioid combinations |
| EA201100544A1 (ru) * | 2006-11-07 | 2012-01-30 | Нектар Терапьютикс | Применение комбинации опиоидного агониста и конъюгата полимер-опиоидный антагонист для изготовления лекарственного средства для лечения и предупреждения боли |
| US8173666B2 (en) | 2007-03-12 | 2012-05-08 | Nektar Therapeutics | Oligomer-opioid agonist conjugates |
| RS53937B1 (sr) | 2007-03-12 | 2015-08-31 | Nektar Therapeutics | Konjugati oligomerno-opioidnog agonista |
| EP2022778A1 (en) * | 2007-08-07 | 2009-02-11 | Laboratorios del Dr. Esteve S.A. | A crystalline form of (R,R)-tramadol-(S)-naproxene salt |
| JP5827123B2 (ja) | 2008-09-16 | 2015-12-02 | ウェルズ ファーゴ バンク ナショナル アソシエイション | 乱用の可能性が低いｐｅｇ化オピオイド |
| CA2750144C (en) * | 2008-12-31 | 2016-10-25 | Upsher-Smith Laboratories, Inc. | Opioid-containing oral pharmaceutical compositions and methods |
| EP2456469A1 (en) | 2009-07-21 | 2012-05-30 | Nektar Therapeutics | Oligomer-opioid agonist conjugates |
| US8551949B2 (en) * | 2009-07-27 | 2013-10-08 | Nocicepta Llc | Methods for treatment of pain |
| US8202525B2 (en) * | 2009-12-22 | 2012-06-19 | Pondera Biotechnologies, LLC | Methods and compositions for treating distress dysfunction and enhancing safety and efficacy of specific medications |
| US20130023553A1 (en) | 2010-01-12 | 2013-01-24 | Nektar Therapeutics | Pegylated opioids with low potential for abuse and side effects |
| CA2854512A1 (en) | 2011-11-07 | 2013-05-16 | Nektar Therapeutics | Compositions, dosage forms, and co-administration of an opioid agonist compound and an analgesic compound |
-
2012
- 2012-11-06 CA CA2854512A patent/CA2854512A1/en not_active Abandoned
- 2012-11-06 KR KR1020147015187A patent/KR102016305B1/ko not_active Expired - Fee Related
- 2012-11-06 EP EP12798075.3A patent/EP2776046A1/en not_active Withdrawn
- 2012-11-06 WO PCT/US2012/063725 patent/WO2013070617A1/en not_active Ceased
- 2012-11-06 CN CN201280054543.0A patent/CN103906522B/zh not_active Expired - Fee Related
- 2012-11-06 JP JP2014540197A patent/JP6593993B2/ja not_active Expired - Fee Related
- 2012-11-06 US US14/356,486 patent/US9457024B2/en active Active
- 2012-11-06 AU AU2012336030A patent/AU2012336030B2/en not_active Ceased
- 2012-11-06 MX MX2014005571A patent/MX348933B/es active IP Right Grant
-
2016
- 2016-09-01 US US15/254,830 patent/US9925182B2/en active Active
-
2018
- 2018-06-22 JP JP2018118989A patent/JP2018158940A/ja not_active Withdrawn