JP2014530842A5 - - Google Patents

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Publication number
JP2014530842A5
JP2014530842A5 JP2014536290A JP2014536290A JP2014530842A5 JP 2014530842 A5 JP2014530842 A5 JP 2014530842A5 JP 2014536290 A JP2014536290 A JP 2014536290A JP 2014536290 A JP2014536290 A JP 2014536290A JP 2014530842 A5 JP2014530842 A5 JP 2014530842A5
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JP
Japan
Prior art keywords
pharmaceutical composition
group
transthyretin
pharmaceutically acceptable
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014536290A
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English (en)
Japanese (ja)
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JP6068484B2 (ja
JP2014530842A (ja
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Publication date
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Priority claimed from PCT/EP2012/070945 external-priority patent/WO2013060668A1/en
Publication of JP2014530842A publication Critical patent/JP2014530842A/ja
Publication of JP2014530842A5 publication Critical patent/JP2014530842A5/ja
Application granted granted Critical
Publication of JP6068484B2 publication Critical patent/JP6068484B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2014536290A 2011-10-24 2012-10-23 トランスサイレチン関連アミロイドーシスの新規療法 Active JP6068484B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11382326.4 2011-10-24
EP11382326 2011-10-24
PCT/EP2012/070945 WO2013060668A1 (en) 2011-10-24 2012-10-23 New therapy for transthyretin-associated amyloidosis

Publications (3)

Publication Number Publication Date
JP2014530842A JP2014530842A (ja) 2014-11-20
JP2014530842A5 true JP2014530842A5 (https=) 2015-12-10
JP6068484B2 JP6068484B2 (ja) 2017-01-25

Family

ID=47076222

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014536290A Active JP6068484B2 (ja) 2011-10-24 2012-10-23 トランスサイレチン関連アミロイドーシスの新規療法

Country Status (19)

Country Link
US (5) US9610270B2 (https=)
EP (1) EP2770988B1 (https=)
JP (1) JP6068484B2 (https=)
KR (1) KR102017354B1 (https=)
CN (1) CN103889407B (https=)
AU (2) AU2012327275B2 (https=)
BR (1) BR112014009322B1 (https=)
CA (1) CA2852808C (https=)
CL (1) CL2014000893A1 (https=)
CY (1) CY1118151T1 (https=)
ES (1) ES2593038T3 (https=)
IL (1) IL231907B (https=)
MX (2) MX347784B (https=)
PL (1) PL2770988T3 (https=)
PT (1) PT2770988T (https=)
RU (2) RU2747536C2 (https=)
SG (2) SG11201401215VA (https=)
WO (1) WO2013060668A1 (https=)
ZA (1) ZA201402546B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2747536C2 (ru) * 2011-10-24 2021-05-06 Сом Инновэйшн Биотек, С.Л. Новая терапия транстиретин-ассоциированного амилоидоза
CN113599539A (zh) * 2014-08-29 2021-11-05 阿尔尼拉姆医药品有限公司 治疗甲状腺素运载蛋白(ttr)介导的淀粉样变性的方法
EP3275433A1 (en) * 2016-07-29 2018-01-31 Som Innovation Biotech S.L. Sustained release composition comprising micronized tolcapone
AU2019236469A1 (en) * 2018-03-12 2020-10-08 Corino Therapeutics, Inc. Combination therapy for TTR amyloidosis
CA3141998A1 (en) * 2019-05-31 2020-12-03 Plex Pharmaceuticals, Inc. Pharmacological agents for treating protein aggregation diseases of the eye
EP4243798A4 (en) * 2020-11-13 2024-08-21 Plex Pharmaceuticals, Inc. PHARMACOLOGICAL AGENTS FOR TREATING OCULAR PATHOLOGIES
CN114324693B (zh) * 2022-01-14 2023-01-13 大连博源医学科技有限公司 一种血液中转甲状腺素蛋白(ttr)四聚体浓度测定的预处理方法和检测方法
JP2025536853A (ja) * 2022-10-10 2025-11-07 コリノ セラピューティクス,インク. 放出調節トルカポン処方剤

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5744368A (en) 1993-11-04 1998-04-28 Research Foundation Of State University Of New York Methods for the detection of soluble amyloid β-protein (βAP) or soluble transthyretin (TTR)
AU5727798A (en) 1996-12-23 1998-07-17 Texas A & M University, The Anti-amyloidogenic agents
FI20002044A0 (fi) * 2000-09-15 2000-09-15 Orion Yhtymae Oyj Comt-entsyymiä estäviä naftaleenijohdannaisia
EP1372682B1 (en) 2001-03-15 2012-05-02 Proteotech Inc. Catechins for the treatment of fibrillogenesis in alzheimer's disease, parkinson's disease, systemic aa amyloidosis, and other amyloid disorders
WO2003063880A1 (en) 2002-01-29 2003-08-07 Protemix Corporation Limited Disruption of islet amyloid by polycyclic compounds
US20040175382A1 (en) 2003-03-06 2004-09-09 Schafer Peter H. Methods of using and compositions comprising selective cytokine inhibitory drugs for the treatment and management of disorders of the central nervous system
KR20060124712A (ko) 2004-02-20 2006-12-05 노파르티스 아게 신경퇴행 및 인지 장애를 치료하기 위한 dpp ⅳ 억제제
CN1921856A (zh) * 2004-02-20 2007-02-28 诺瓦提斯公司 用于治疗神经变性疾病和认知障碍的dpp-iv抑制剂
WO2005113523A1 (en) 2004-05-20 2005-12-01 Foldrx Pharmaceuticals, Inc. 2-((hetero) aryl)-benzoxazole compounds and derivatives, compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding
DE602005019582D1 (de) 2004-08-30 2010-04-08 Seo Hong Yoo Nervenschutzwirkung von aufgelöster udca bei einem fokalen ischämischen modell
GB2429645A (en) 2006-03-10 2007-03-07 Sekhsaria Chemicals Ltd Solid pharmaceutical composition comprising a COMT inhibitor, a starch and a wetting agent
US20120016037A1 (en) 2006-07-24 2012-01-19 Frank Toppo Method for prevention and treatment of Alzheimers
GB0718718D0 (en) 2007-09-25 2007-11-07 Pentraxin Therapeutics Ltd Compound and use thereof
DE102010010572A1 (de) 2010-03-08 2011-09-08 Mahle International Gmbh Trockenseparator
RU2747536C2 (ru) * 2011-10-24 2021-05-06 Сом Инновэйшн Биотек, С.Л. Новая терапия транстиретин-ассоциированного амилоидоза

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