JP2014529399A5 - - Google Patents
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- Publication number
- JP2014529399A5 JP2014529399A5 JP2014525175A JP2014525175A JP2014529399A5 JP 2014529399 A5 JP2014529399 A5 JP 2014529399A5 JP 2014525175 A JP2014525175 A JP 2014525175A JP 2014525175 A JP2014525175 A JP 2014525175A JP 2014529399 A5 JP2014529399 A5 JP 2014529399A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- polypeptide
- residue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 21
- 125000003275 alpha amino acid group Chemical group 0.000 claims 17
- 239000008194 pharmaceutical composition Substances 0.000 claims 7
- 150000007523 nucleic acids Chemical class 0.000 claims 6
- 108020004707 nucleic acids Proteins 0.000 claims 6
- 206010009839 Coeliac disease Diseases 0.000 claims 5
- 150000001413 amino acids Chemical class 0.000 claims 5
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims 2
- 230000000593 degrading Effects 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161521899P | 2011-08-10 | 2011-08-10 | |
| US61/521,899 | 2011-08-10 | ||
| PCT/US2012/050364 WO2013023151A2 (en) | 2011-08-10 | 2012-08-10 | Compositions and methods for treating celiac sprue disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017133615A Division JP6502428B2 (ja) | 2011-08-10 | 2017-07-07 | セリアックスプルー病を治療するための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014529399A JP2014529399A (ja) | 2014-11-13 |
| JP2014529399A5 true JP2014529399A5 (US20090208454A1-20090820-C00047.png) | 2015-09-03 |
| JP6342802B2 JP6342802B2 (ja) | 2018-06-13 |
Family
ID=46690751
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014525175A Active JP6342802B2 (ja) | 2011-08-10 | 2012-08-10 | セリアックスプルー病を治療するための組成物および方法 |
| JP2017133615A Active JP6502428B2 (ja) | 2011-08-10 | 2017-07-07 | セリアックスプルー病を治療するための組成物および方法 |
| JP2019052599A Pending JP2019162107A (ja) | 2011-08-10 | 2019-03-20 | セリアックスプルー病を治療するための組成物および方法 |
| JP2021048356A Pending JP2021094031A (ja) | 2011-08-10 | 2021-03-23 | セリアックスプルー病を治療するための組成物および方法 |
| JP2024002401A Pending JP2024028452A (ja) | 2011-08-10 | 2024-01-11 | セリアックスプルー病を治療するための組成物および方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017133615A Active JP6502428B2 (ja) | 2011-08-10 | 2017-07-07 | セリアックスプルー病を治療するための組成物および方法 |
| JP2019052599A Pending JP2019162107A (ja) | 2011-08-10 | 2019-03-20 | セリアックスプルー病を治療するための組成物および方法 |
| JP2021048356A Pending JP2021094031A (ja) | 2011-08-10 | 2021-03-23 | セリアックスプルー病を治療するための組成物および方法 |
| JP2024002401A Pending JP2024028452A (ja) | 2011-08-10 | 2024-01-11 | セリアックスプルー病を治療するための組成物および方法 |
Country Status (17)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2718434B1 (en) | 2011-08-10 | 2018-03-28 | University of Washington through its Center for Commercialization | Compositions and methods for treating celiac sprue disease |
| EP4008340A1 (en) | 2013-08-14 | 2022-06-08 | University of Washington Through Its Center for Commercialization | Compositions for treating celiac sprue disease |
| EP3081942A1 (en) * | 2015-04-17 | 2016-10-19 | Roche Diagniostics GmbH | Pressure transmission liquid for cellular analyzer, cellular analyzer and method for analyzing a liquid cellular sample |
| EA037603B1 (ru) * | 2015-06-08 | 2021-04-20 | Юниверсити Оф Вашингтон | Композиции и способы для лечения целиакии спру |
| KR102553627B1 (ko) | 2016-12-22 | 2023-07-07 | 에베 누트리찌온 게엠베하 | 안정한 프로테아제 변이체 |
| WO2020087017A1 (en) * | 2018-10-26 | 2020-04-30 | The Regents Of The University Of California | Use of proteolytic enzymes to enhance protein bioavailability |
| CN116829166A (zh) | 2020-10-30 | 2023-09-29 | 华盛顿大学 | 用于治疗乳糜泻的组合物和方法 |
| WO2023147350A1 (en) | 2022-01-26 | 2023-08-03 | Digestiva, Inc. | Blood glucose stabilizing methods and compositions |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2688229B1 (fr) | 1992-03-09 | 1995-06-23 | Ulice Soc | Procede de synthese enzymatique d'esters alkyliques de peptides, produits ainsi obtenus et utilisation desdits produits. |
| JP2002078489A (ja) * | 2000-09-04 | 2002-03-19 | Daiwa Kasei Kk | セリン残基が活性発現に関与する新規酸性プロテアーゼ |
| US8143210B2 (en) | 2002-02-14 | 2012-03-27 | The Board Of Trustees Of The Leland Stanford Junior University | Enzyme treatment of foodstuffs for celiac sprue |
| US7320788B2 (en) * | 2002-02-14 | 2008-01-22 | The Board Of Trustees Of The Leland Stanford Junior University | Enzyme treatment of foodstuffs for Celiac Sprue |
| DK1572127T4 (da) | 2002-02-14 | 2014-11-24 | Univ Leland Stanford Junior | Enzymbehandling af fødevarer til cøliaki |
| US7462688B2 (en) | 2002-05-14 | 2008-12-09 | The Board Of Trustees Of The Leland Stanford Junior University | Peptides for diagnostic and therapeutic methods for celiac sprue |
| EP1507549A4 (en) | 2002-05-14 | 2009-07-01 | Univ Leland Stanford Junior | MEDICAMENT THERAPY AGAINST CELIAC SPRUE |
| US7202216B2 (en) | 2002-05-14 | 2007-04-10 | The Board Of Trustees Of The Leland Stanford Junior University | Drug therapy for celiac sprue |
| US7265093B2 (en) | 2002-05-14 | 2007-09-04 | The Board Of Trustees Of The Leland Stanford Junior University | Drug therapy for Celiac Sprue |
| CA2502700C (en) | 2002-11-20 | 2017-01-17 | Chaitan Khosla | Diagnostic method for celiac sprue |
| US7579313B2 (en) | 2003-11-18 | 2009-08-25 | The Board Of Trustees Of The Leland Stanford Junior University | Transglutaminase inhibitors and methods of use thereof |
| US7628985B2 (en) | 2004-04-26 | 2009-12-08 | The Board Of Regents Of The Leland Stanford Junior University | Therapeutic enzyme formulations and uses thereof in celiac sprue and/or dermatitis herpetoformis |
| US7563864B2 (en) | 2004-04-26 | 2009-07-21 | Celiac Sprue Research Foundation | Prolyl endopeptidase mediated destruction of T cell epitopes in whole gluten |
| US7534426B2 (en) | 2004-04-26 | 2009-05-19 | The Board Of Trustees Of The Leland Stanford Junior University | Glutenase enzyme assays |
| EP1600141B1 (en) | 2004-05-24 | 2013-04-17 | 3M Deutschland GmbH | Collagenolytic active enzyme containing compositions for the treatment of dental caries |
| EP1726643A1 (en) * | 2005-05-27 | 2006-11-29 | Direvo Biotech AG | Method for the provision, identification and selection of proteases with altered sensitivity to activity-modulating substances |
| CA2733514C (en) | 2008-08-21 | 2017-10-24 | Alvine Pharmaceuticals, Inc. | Formulation for oral administration of proteins |
| EP2718434B1 (en) * | 2011-08-10 | 2018-03-28 | University of Washington through its Center for Commercialization | Compositions and methods for treating celiac sprue disease |
| IN2014CN04131A (US20090208454A1-20090820-C00047.png) | 2011-12-06 | 2015-07-17 | Fond Istituto Insubrico Di Ricerca Per La Vita | |
| EP4008340A1 (en) | 2013-08-14 | 2022-06-08 | University of Washington Through Its Center for Commercialization | Compositions for treating celiac sprue disease |
-
2012
- 2012-08-10 EP EP12748354.3A patent/EP2718434B1/en active Active
- 2012-08-10 EP EP21187810.3A patent/EP4023243A3/en active Pending
- 2012-08-10 NO NO12748354A patent/NO2718434T3/no unknown
- 2012-08-10 DK DK12748354.3T patent/DK2718434T3/en active
- 2012-08-10 PT PT127483543T patent/PT2718434T/pt unknown
- 2012-08-10 EP EP18162586.4A patent/EP3400958B1/en active Active
- 2012-08-10 LT LTEP12748354.3T patent/LT2718434T/lt unknown
- 2012-08-10 ES ES18162586T patent/ES2896489T3/es active Active
- 2012-08-10 WO PCT/US2012/050364 patent/WO2013023151A2/en active Application Filing
- 2012-08-10 RS RS20180609A patent/RS57234B1/sr unknown
- 2012-08-10 SI SI201231269T patent/SI2718434T1/en unknown
- 2012-08-10 HU HUE12748354A patent/HUE037870T2/hu unknown
- 2012-08-10 CA CA2882502A patent/CA2882502A1/en active Pending
- 2012-08-10 PL PL18162586T patent/PL3400958T3/pl unknown
- 2012-08-10 TR TR2018/06885T patent/TR201806885T4/tr unknown
- 2012-08-10 JP JP2014525175A patent/JP6342802B2/ja active Active
- 2012-08-10 ES ES12748354.3T patent/ES2667418T3/es active Active
- 2012-08-10 PL PL12748354T patent/PL2718434T3/pl unknown
- 2012-08-10 US US14/131,601 patent/US9289473B2/en active Active
-
2016
- 2016-01-26 US US15/006,341 patent/US9707280B2/en active Active
-
2017
- 2017-06-26 US US15/633,065 patent/US9925249B2/en active Active
- 2017-07-07 JP JP2017133615A patent/JP6502428B2/ja active Active
-
2018
- 2018-02-14 US US15/896,536 patent/US10149892B2/en active Active
- 2018-05-03 HR HRP20180687TT patent/HRP20180687T1/hr unknown
- 2018-06-21 CY CY181100648T patent/CY1120877T1/el unknown
- 2018-11-28 US US16/203,109 patent/US10874720B2/en active Active
-
2019
- 2019-03-20 JP JP2019052599A patent/JP2019162107A/ja active Pending
-
2020
- 2020-12-07 US US17/114,294 patent/US20210085761A1/en not_active Abandoned
-
2021
- 2021-03-23 JP JP2021048356A patent/JP2021094031A/ja active Pending
-
2024
- 2024-01-11 JP JP2024002401A patent/JP2024028452A/ja active Pending
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