JP2014523516A5 - - Google Patents
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- Publication number
- JP2014523516A5 JP2014523516A5 JP2014508165A JP2014508165A JP2014523516A5 JP 2014523516 A5 JP2014523516 A5 JP 2014523516A5 JP 2014508165 A JP2014508165 A JP 2014508165A JP 2014508165 A JP2014508165 A JP 2014508165A JP 2014523516 A5 JP2014523516 A5 JP 2014523516A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- inhibitor
- pathway
- hsp90
- component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161480198P | 2011-04-28 | 2011-04-28 | |
| US61/480,198 | 2011-04-28 | ||
| PCT/US2012/035690 WO2012149493A2 (en) | 2011-04-28 | 2012-04-27 | Hsp90 combination therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016175431A Division JP6375345B2 (ja) | 2011-04-28 | 2016-09-08 | Hsp90併用療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014523516A JP2014523516A (ja) | 2014-09-11 |
| JP2014523516A5 true JP2014523516A5 (enExample) | 2015-06-18 |
| JP6363502B2 JP6363502B2 (ja) | 2018-07-25 |
Family
ID=47073116
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014508165A Expired - Fee Related JP6363502B2 (ja) | 2011-04-28 | 2012-04-27 | Hsp90併用療法 |
| JP2016175431A Expired - Fee Related JP6375345B2 (ja) | 2011-04-28 | 2016-09-08 | Hsp90併用療法 |
| JP2018106047A Withdrawn JP2018153194A (ja) | 2011-04-28 | 2018-06-01 | Hsp90併用療法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016175431A Expired - Fee Related JP6375345B2 (ja) | 2011-04-28 | 2016-09-08 | Hsp90併用療法 |
| JP2018106047A Withdrawn JP2018153194A (ja) | 2011-04-28 | 2018-06-01 | Hsp90併用療法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20140315929A1 (enExample) |
| EP (1) | EP2701747A4 (enExample) |
| JP (3) | JP6363502B2 (enExample) |
| KR (2) | KR102027448B1 (enExample) |
| CN (2) | CN109498812A (enExample) |
| AU (3) | AU2012249322B2 (enExample) |
| BR (1) | BR112013027448A2 (enExample) |
| CA (1) | CA2833390A1 (enExample) |
| EA (1) | EA201391587A1 (enExample) |
| MX (1) | MX2013012183A (enExample) |
| NZ (1) | NZ618062A (enExample) |
| WO (1) | WO2012149493A2 (enExample) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2841069C (en) | 2011-07-08 | 2021-11-23 | Sloan-Kettering Institute For Cancer Research | Uses of labeled hsp90 inhibitors |
| US20140079636A1 (en) * | 2012-04-16 | 2014-03-20 | Dinesh U. Chimmanamada | Targeted therapeutics |
| US8993555B2 (en) | 2012-12-21 | 2015-03-31 | Epizyme, Inc. | PRMT5 inhibitors and uses thereof |
| WO2015089402A1 (en) * | 2013-12-12 | 2015-06-18 | The University Of Chicago | Methods and compositions related to hsp90 inhibitors and breast cancer |
| AU2014386214B2 (en) | 2013-12-23 | 2020-05-21 | Memorial Sloan-Kettering Cancer Center | Methods and reagents for radiolabeling |
| WO2015168599A1 (en) * | 2014-05-02 | 2015-11-05 | The Wistar Institute Of Anatomy And Biology | Combination therapies targeting mitochondria for cancer therapy |
| BR112017005313A2 (pt) | 2014-09-17 | 2017-12-05 | Memorial Sloan Kettering Cancer Center | formação de imagem e terapia para inflamação e infecção direcionadas por hsp90 |
| US9710606B2 (en) | 2014-10-21 | 2017-07-18 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues |
| US10325685B2 (en) | 2014-10-21 | 2019-06-18 | uBiome, Inc. | Method and system for characterizing diet-related conditions |
| US10793907B2 (en) | 2014-10-21 | 2020-10-06 | Psomagen, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions |
| US10346592B2 (en) | 2014-10-21 | 2019-07-09 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues |
| US10381112B2 (en) | 2014-10-21 | 2019-08-13 | uBiome, Inc. | Method and system for characterizing allergy-related conditions associated with microorganisms |
| US10409955B2 (en) | 2014-10-21 | 2019-09-10 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for locomotor system conditions |
| US9760676B2 (en) | 2014-10-21 | 2017-09-12 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions |
| US11783914B2 (en) | 2014-10-21 | 2023-10-10 | Psomagen, Inc. | Method and system for panel characterizations |
| US10073952B2 (en) | 2014-10-21 | 2018-09-11 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions |
| US10388407B2 (en) | 2014-10-21 | 2019-08-20 | uBiome, Inc. | Method and system for characterizing a headache-related condition |
| US10777320B2 (en) | 2014-10-21 | 2020-09-15 | Psomagen, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for mental health associated conditions |
| US10169541B2 (en) | 2014-10-21 | 2019-01-01 | uBiome, Inc. | Method and systems for characterizing skin related conditions |
| US9758839B2 (en) | 2014-10-21 | 2017-09-12 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome functional features |
| US10265009B2 (en) | 2014-10-21 | 2019-04-23 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome taxonomic features |
| US10410749B2 (en) | 2014-10-21 | 2019-09-10 | uBiome, Inc. | Method and system for microbiome-derived characterization, diagnostics and therapeutics for cutaneous conditions |
| EP3209803A4 (en) | 2014-10-21 | 2018-06-13 | Ubiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics |
| US9754080B2 (en) | 2014-10-21 | 2017-09-05 | uBiome, Inc. | Method and system for microbiome-derived characterization, diagnostics and therapeutics for cardiovascular disease conditions |
| US10357157B2 (en) | 2014-10-21 | 2019-07-23 | uBiome, Inc. | Method and system for microbiome-derived characterization, diagnostics and therapeutics for conditions associated with functional features |
| US10789334B2 (en) | 2014-10-21 | 2020-09-29 | Psomagen, Inc. | Method and system for microbial pharmacogenomics |
| US10311973B2 (en) | 2014-10-21 | 2019-06-04 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions |
| US10366793B2 (en) | 2014-10-21 | 2019-07-30 | uBiome, Inc. | Method and system for characterizing microorganism-related conditions |
| US10395777B2 (en) | 2014-10-21 | 2019-08-27 | uBiome, Inc. | Method and system for characterizing microorganism-associated sleep-related conditions |
| WO2016168344A1 (en) * | 2015-04-13 | 2016-10-20 | uBiome, Inc. | Method and system for microbiome-derived characterization, diaganostics and therapeutics for conditions associated with functional features |
| US10246753B2 (en) | 2015-04-13 | 2019-04-02 | uBiome, Inc. | Method and system for characterizing mouth-associated conditions |
| CN106265660B (zh) * | 2015-05-21 | 2019-08-02 | 中国科学院合肥物质科学研究院 | A674563在携带flt3突变型基因的急性白血病中的用途 |
| CN106349180B (zh) * | 2015-07-14 | 2020-05-19 | 上海翰森生物医药科技有限公司 | 4,5-二苯基异噁唑衍生物及其制备方法和应用 |
| WO2018027084A2 (en) * | 2016-08-03 | 2018-02-08 | Remd Biotherapeutics, Inc. | Combination of glucagon receptor antagonists and pi3k pathway inhibitors for the treatment of cancer |
| TW201840337A (zh) | 2017-02-03 | 2018-11-16 | 美商藍治療公司 | 使用hsp90抑制劑治療癌症的方法 |
| JP2020524156A (ja) | 2017-06-20 | 2020-08-13 | マドリガル ファーマシューティカルズ インコーポレイテッドMadrigal Pharmaceuticals,Inc. | 標的治療薬を含む併用療法 |
| JP2020524154A (ja) | 2017-06-20 | 2020-08-13 | マドリガル ファーマシューティカルズ インコーポレイテッドMadrigal Pharmaceuticals,Inc. | 標的治療薬 |
| JP7558167B2 (ja) | 2018-12-03 | 2024-09-30 | ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム | オリゴベンズアミド類似体およびがん処置におけるそれらの使用 |
| CN109554343B (zh) * | 2018-12-29 | 2022-04-19 | 吉林大学 | 一种适于神经元粘附与存活的涂层材料及制备方法 |
| WO2020206608A1 (en) | 2019-04-09 | 2020-10-15 | Ranok Therapeutics (Hangzhou) Co., Ltd. | Methods and compositions for targeted protein degradation |
| CN111467472B (zh) * | 2020-04-21 | 2020-12-25 | 南京中医药大学 | 一种靶向肿瘤相关巨噬细胞的免疫调节微球制剂及其制备方法与应用 |
| WO2021252490A2 (en) * | 2020-06-11 | 2021-12-16 | The Children's Medical Center Corporation | Use of heat shock protein inhibitors for the treatment of neurodevelopmental disorders |
| KR20240073137A (ko) | 2020-09-09 | 2024-05-24 | 소셜 프로핏 네트워크 | 미토콘드리아에 비오틴의 전달을 위한 방법 및 조성물 |
| IL302081A (en) * | 2020-10-14 | 2023-06-01 | Ranok Therapeutics Hangzhou Co Ltd | Methods and compositions for targeted protein degradation |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6303652B1 (en) * | 1998-08-21 | 2001-10-16 | Hughes Institute | BTK inhibitors and methods for their identification and use |
| US20070105874A1 (en) | 2005-09-23 | 2007-05-10 | Conforma Therapeutics Corporation | Anti-Tumor Methods Using Multi Drug Resistance Independent Synthetic HSP90 Inhibitors |
| JP5721949B2 (ja) * | 2006-10-12 | 2015-05-20 | アステックス、セラピューティックス、リミテッドAstex Therapeutics Limited | 複合薬剤 |
| EP2491923A3 (en) * | 2007-02-15 | 2012-12-26 | Novartis AG | Combinations of therapeutic agents for treating cancer |
| WO2008114812A1 (ja) * | 2007-03-19 | 2008-09-25 | Kyowa Hakko Kirin Co., Ltd. | Jak阻害剤 |
| KR20140098185A (ko) * | 2007-07-30 | 2014-08-07 | 아디아 바이오사이언스즈 인크. | 다형체를 포함하는, mek의 억제제로서의 n-(아릴아미노) 술폰아미드의 유도체 및 조성물, 사용 방법 및 이의 제조 방법 |
| US20100310563A1 (en) * | 2007-11-30 | 2010-12-09 | Bumm Thomas G P | Methods for treating induced cellular proliferative disorders |
| WO2010006072A2 (en) * | 2008-07-08 | 2010-01-14 | The Regents Of The University Of California | Mtor modulators and uses thereof |
| EP2321645A1 (en) * | 2008-08-18 | 2011-05-18 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Susceptibility to hsp90-inhibitors |
| ES2621141T3 (es) * | 2008-11-28 | 2017-07-03 | Novartis Ag | Combinación farmacéutica que comprende un inhibidor de Hsp 90 y un inhibidor de mTOR |
| US8669289B2 (en) | 2009-04-24 | 2014-03-11 | The Jackson Laboratory | Methods and compositions relating to hematologic malignancies |
| ES2632220T3 (es) * | 2009-06-15 | 2017-09-11 | Rigel Pharmaceuticals, Inc. | Inhibidores de moléculas pequeñas de tirosina cinasa del bazo (SYK) |
| NZ598262A (en) * | 2009-08-17 | 2014-05-30 | Sloan Kettering Inst Cancer | Heat shock protein binding compounds, compositions, and methods for making and using same |
| CN102713606A (zh) * | 2009-11-13 | 2012-10-03 | 无限制药股份有限公司 | 用于鉴定、评估、预防和治疗癌症的组合物、试剂盒和方法 |
| NZ772688A (en) * | 2010-06-03 | 2022-09-30 | Pharmacyclics Llc | The use of inhibitors of bruton’s tyrosine kinase (btk) |
| US20140315943A1 (en) * | 2011-05-24 | 2014-10-23 | Synta Pharmaceuticals Corp. | Combination therapy of hsp90 inhibitory compounds with mtor/p13k inhibitors |
-
2012
- 2012-04-27 BR BR112013027448-4A patent/BR112013027448A2/pt not_active IP Right Cessation
- 2012-04-27 CN CN201811083946.3A patent/CN109498812A/zh active Pending
- 2012-04-27 CN CN201280030064.5A patent/CN103998935B/zh not_active Expired - Fee Related
- 2012-04-27 EA EA201391587A patent/EA201391587A1/ru unknown
- 2012-04-27 MX MX2013012183A patent/MX2013012183A/es unknown
- 2012-04-27 WO PCT/US2012/035690 patent/WO2012149493A2/en not_active Ceased
- 2012-04-27 CA CA2833390A patent/CA2833390A1/en not_active Abandoned
- 2012-04-27 AU AU2012249322A patent/AU2012249322B2/en not_active Ceased
- 2012-04-27 KR KR1020137031561A patent/KR102027448B1/ko not_active Expired - Fee Related
- 2012-04-27 US US14/113,779 patent/US20140315929A1/en not_active Abandoned
- 2012-04-27 EP EP12777773.8A patent/EP2701747A4/en not_active Withdrawn
- 2012-04-27 KR KR1020197028143A patent/KR102196424B1/ko not_active Expired - Fee Related
- 2012-04-27 JP JP2014508165A patent/JP6363502B2/ja not_active Expired - Fee Related
- 2012-04-27 NZ NZ618062A patent/NZ618062A/en not_active IP Right Cessation
-
2016
- 2016-09-08 JP JP2016175431A patent/JP6375345B2/ja not_active Expired - Fee Related
-
2017
- 2017-12-08 AU AU2017272303A patent/AU2017272303A1/en not_active Abandoned
-
2018
- 2018-06-01 JP JP2018106047A patent/JP2018153194A/ja not_active Withdrawn
-
2020
- 2020-01-14 AU AU2020200262A patent/AU2020200262A1/en not_active Abandoned
- 2020-08-28 US US17/006,359 patent/US20220074941A1/en not_active Abandoned
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