JP2014523421A5 - - Google Patents
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- Publication number
- JP2014523421A5 JP2014523421A5 JP2014516039A JP2014516039A JP2014523421A5 JP 2014523421 A5 JP2014523421 A5 JP 2014523421A5 JP 2014516039 A JP2014516039 A JP 2014516039A JP 2014516039 A JP2014516039 A JP 2014516039A JP 2014523421 A5 JP2014523421 A5 JP 2014523421A5
- Authority
- JP
- Japan
- Prior art keywords
- dll4
- formulation
- ionizing radiation
- cancer
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161498200P | 2011-06-17 | 2011-06-17 | |
| US61/498,200 | 2011-06-17 | ||
| PCT/US2012/042695 WO2012174394A1 (en) | 2011-06-17 | 2012-06-15 | Methods of enhancing the response to radiation in tumor therapy using anti-dll4 antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014523421A JP2014523421A (ja) | 2014-09-11 |
| JP2014523421A5 true JP2014523421A5 (https=) | 2015-08-06 |
Family
ID=46397640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014516039A Ceased JP2014523421A (ja) | 2011-06-17 | 2012-06-15 | 抗ｄｌｌ４抗体を使用して腫瘍治療における放射線に対する反応を増大させる方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8685401B2 (https=) |
| EP (1) | EP2721070A1 (https=) |
| JP (1) | JP2014523421A (https=) |
| AU (1) | AU2012271450A1 (https=) |
| CA (1) | CA2838973A1 (https=) |
| WO (1) | WO2012174394A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2700450T3 (es) | 2009-10-16 | 2019-02-15 | Oncomed Pharm Inc | Combinación terapéutica y uso de anticuerpos antagonistas de DLL4 y agentes antihipertensores |
| LT3485903T (lt) | 2011-09-23 | 2023-02-27 | Mereo Biopharma 5, Inc. | Vegf/ dll4 surišantys agentai ir jų panaudojimas |
| WO2016070051A2 (en) | 2014-10-31 | 2016-05-06 | Oncomed Pharmaceuticals, Inc. | Combination therapy for treatment of disease |
| EP3353204B1 (en) | 2015-09-23 | 2023-10-18 | Mereo BioPharma 5, Inc. | Bi-specific anti-vegf/dll4 antibody for use in treating platinum-resistant ovarian cancer |
| TWI821189B (zh) * | 2017-06-12 | 2023-11-11 | 法商施維雅藥廠 | 使用組合療法治療腦腫瘤之方法 |
| TW202440123A (zh) * | 2017-06-12 | 2024-10-16 | 法商施維雅藥廠 | 以組合療法治療腦瘤之方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
| US5229275A (en) | 1990-04-26 | 1993-07-20 | Akzo N.V. | In-vitro method for producing antigen-specific human monoclonal antibodies |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| ATE199392T1 (de) | 1992-12-04 | 2001-03-15 | Medical Res Council | Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung |
| US5916771A (en) | 1996-10-11 | 1999-06-29 | Abgenix, Inc. | Production of a multimeric protein by cell fusion method |
| EA018260B1 (ru) * | 2006-09-29 | 2013-06-28 | Онкомед Фармасьютикалз, Инк. | Антитела к дельта-подобному лиганду 4 человека и их применение |
| RU2581962C2 (ru) | 2008-09-19 | 2016-04-20 | Медиммун Ллк | Нацеленные средства связывания, направленные на dll4, и их применение |
| US20110059114A1 (en) * | 2009-08-05 | 2011-03-10 | Duke University | Compositions and Methods for the Treatment of Radioresistant Glioma Stem Cells |
| US9209965B2 (en) | 2014-01-14 | 2015-12-08 | Microsemi Semiconductor Ulc | Network interface with clock recovery module on line card |
-
2012
- 2012-06-15 AU AU2012271450A patent/AU2012271450A1/en not_active Abandoned
- 2012-06-15 EP EP12730733.8A patent/EP2721070A1/en not_active Withdrawn
- 2012-06-15 WO PCT/US2012/042695 patent/WO2012174394A1/en not_active Ceased
- 2012-06-15 US US13/524,396 patent/US8685401B2/en not_active Expired - Fee Related
- 2012-06-15 JP JP2014516039A patent/JP2014523421A/ja not_active Ceased
- 2012-06-15 CA CA2838973A patent/CA2838973A1/en not_active Abandoned
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