JP2014518542A - 改善されたcckおよびglp−1放出活性を有するタンパク質加水分解組成物 - Google Patents

改善されたcckおよびglp−1放出活性を有するタンパク質加水分解組成物 Download PDF

Info

Publication number
JP2014518542A
JP2014518542A JP2013555539A JP2013555539A JP2014518542A JP 2014518542 A JP2014518542 A JP 2014518542A JP 2013555539 A JP2013555539 A JP 2013555539A JP 2013555539 A JP2013555539 A JP 2013555539A JP 2014518542 A JP2014518542 A JP 2014518542A
Authority
JP
Japan
Prior art keywords
protein
hydrolyzate
soy
composition
glp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2013555539A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014518542A5 (enExample
Inventor
イレーヌ エス クルル
バリー タルク
メアリー ケイ ポーリク
ジェイソン エフ ロンバルディ
Original Assignee
ソレイ リミテッド ライアビリティ カンパニー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ソレイ リミテッド ライアビリティ カンパニー filed Critical ソレイ リミテッド ライアビリティ カンパニー
Publication of JP2014518542A publication Critical patent/JP2014518542A/ja
Publication of JP2014518542A5 publication Critical patent/JP2014518542A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30Dietetic or nutritional methods, e.g. for losing weight
    • AHUMAN NECESSITIES
    • A21BAKING; EDIBLE DOUGHS
    • A21DTREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D2/00Treatment of flour or dough by adding materials thereto before or during baking
    • A21D2/08Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
    • A21D2/24Organic nitrogen compounds
    • A21D2/26Proteins
    • A21D2/268Hydrolysates from proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C11/00Milk substitutes, e.g. coffee whitener compositions
    • A23C11/02Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins
    • A23C11/10Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins containing or not lactose but no other milk components as source of fats, carbohydrates or proteins
    • A23C11/103Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins containing or not lactose but no other milk components as source of fats, carbohydrates or proteins containing only proteins from pulses, oilseeds or nuts, e.g. nut milk
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/12Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/13Fermented milk preparations; Treatment using microorganisms or enzymes using additives
    • A23C9/1322Inorganic compounds; Minerals, including organic salts thereof, oligo-elements; Amino-acids, peptides, protein-hydrolysates or derivatives; Nucleic acids or derivatives; Yeast extract or autolysate; Vitamins; Antibiotics; Bacteriocins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23JPROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00Working-up of proteins for foodstuffs
    • A23J3/14Vegetable proteins
    • A23J3/16Vegetable proteins from soybean
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23JPROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00Working-up of proteins for foodstuffs
    • A23J3/30Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A23J3/346Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of vegetable proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L11/00Pulses, i.e. fruits of leguminous plants, for production of food; Products from legumes; Preparation or treatment thereof
    • A23L11/60Drinks from legumes, e.g. lupine drinks
    • A23L11/65Soy drinks
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/385Concentrates of non-alcoholic beverages
    • A23L2/39Dry compositions
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52Adding ingredients
    • A23L2/66Proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/18Peptides; Protein hydrolysates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Agronomy & Crop Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP2013555539A 2011-02-23 2012-02-23 改善されたcckおよびglp−1放出活性を有するタンパク質加水分解組成物 Pending JP2014518542A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161445593P 2011-02-23 2011-02-23
US61/445,593 2011-02-23
PCT/US2012/026250 WO2012141795A1 (en) 2011-02-23 2012-02-23 Protein hydrolysate compositions having enhanced cck and glp-1 releasing activity

Publications (2)

Publication Number Publication Date
JP2014518542A true JP2014518542A (ja) 2014-07-31
JP2014518542A5 JP2014518542A5 (enExample) 2015-04-09

Family

ID=46001711

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013555539A Pending JP2014518542A (ja) 2011-02-23 2012-02-23 改善されたcckおよびglp−1放出活性を有するタンパク質加水分解組成物

Country Status (8)

Country Link
US (1) US20130331315A1 (enExample)
EP (1) EP2677885A1 (enExample)
JP (1) JP2014518542A (enExample)
CN (1) CN103561589A (enExample)
BR (1) BR112013021468A2 (enExample)
CA (1) CA2825119A1 (enExample)
MX (1) MX2013009772A (enExample)
WO (1) WO2012141795A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2020226046A1 (enExample) * 2019-05-08 2020-11-12

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2948003B1 (en) 2013-01-23 2020-03-18 Bottled Science Limited Skin enhancing beverage composition
CN105164149A (zh) * 2013-01-28 2015-12-16 索莱有限责任公司 具有饱腹感激素释放活性的新型多肽
US9820504B2 (en) 2013-03-08 2017-11-21 Axiom Foods, Inc. Rice protein supplement and methods of use thereof
CN108271917A (zh) 2013-03-08 2018-07-13 艾斯姆食品公司 大米蛋白补充剂
MX387503B (es) * 2013-03-11 2025-03-18 Burcon Nutrascience Mb Corp Producción de producto de proteína de legumbre.
CN105637096A (zh) * 2013-10-04 2016-06-01 英诺威有限公司 动物蛋白质的水解产物、其制造方法及其用途
US20160309755A1 (en) * 2013-12-09 2016-10-27 Abbott Laboratories Nutritional compositions containing rice protein together with pea and/or potato proteins
CN105476030A (zh) * 2015-12-15 2016-04-13 北京天肽生物科技有限公司 一种多功能复合低聚肽营养粉
US11129404B2 (en) 2015-12-28 2021-09-28 Abbott Laboratories Nutritional compositions comprising hydrolyzed protein and a modified fat system and uses thereof
EP3634155A4 (en) 2017-05-12 2021-02-17 Axiom Foods Inc. RICE PRODUCTS AND SYSTEMS AND PROCESSES FOR THEIR PRODUCTION
WO2019081706A1 (en) * 2017-10-26 2019-05-02 Basf Se PROTEIN HYDROLYSATES AS EMULSIFIERS FOR BAKERY PRODUCTS
DE112019005445T5 (de) 2018-10-30 2021-07-15 Michael Foods, Inc. Knuspriges proteinhaltiges lebensmittelprodukt
JP7326022B2 (ja) * 2019-05-17 2023-08-15 ユニ・チャーム株式会社 ペットフード
MX2022004904A (es) * 2019-10-25 2022-08-10 Supplant Foods Llp Un proceso para preparar harina de garbanzos.
JP7282269B2 (ja) * 2020-07-02 2023-05-26 サントリーホールディングス株式会社 ビールテイスト飲料
CN117529235A (zh) * 2021-04-12 2024-02-06 诺维信公司 用于生产人造肉产品的方法
EP4201220A1 (en) * 2021-12-24 2023-06-28 Compagnie Gervais Danone Plant-based composition and process of preparing the same
US20230292803A1 (en) * 2022-01-21 2023-09-21 Premier Nutrition Company, Llc Sweetener composition and resultant beverage product
CN116082451B (zh) * 2022-12-16 2024-08-27 上海理工大学 一种荞麦源促胆囊收缩素分泌肽及其制备方法和应用
CN120732163A (zh) * 2025-08-25 2025-10-03 北京幸福能量健康科技有限公司 提高glp-1激素分泌控制食欲的蛋白质膳食纤维组合物制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005538704A (ja) * 2002-07-01 2005-12-22 ユニリーバー・ナームローゼ・ベンノートシヤープ 満腹誘導組成物
JP2006510367A (ja) * 2002-12-20 2006-03-30 ユニリーバー・ナームローゼ・ベンノートシヤープ 血糖調節組成物
WO2009101134A1 (fr) * 2008-02-12 2009-08-20 Compagnie Des Peches Saint Malo Sante Hydrolysat de proteines de poissons presentant une activite satietogene, compositions nutraceutiques et pharmacologiques comprenant un tel hydrolysat et procede d'obtention
WO2010078461A1 (en) * 2008-12-31 2010-07-08 Solae, Llc Protein hydrolysate compositions having enhanced cck releasing ability

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR7904209A (pt) 1978-07-04 1980-06-17 Novo Industri As Preparacao de protease adequada para mistura a composicoes de lavagem processo para preparatease cepa de b licheniformis e composicao de lavagem
US5288627A (en) 1988-01-07 1994-02-22 Novo Nordisk A/S Endoprotease from Fusarium oxysporumDSM 2672 for use in detergents
CA2003078A1 (en) 1988-11-18 1990-05-18 Alan Sloma Protease deletion
DK19991D0 (da) 1991-02-06 1991-02-06 Novo Nordisk As Proteinpraeparationer
DK63490D0 (da) 1990-03-09 1990-03-09 Novo Nordisk As Fremgangsmaade til fremstilling af ost
JP3153237B2 (ja) 1990-03-09 2001-04-03 ノボ ノルディスク アクティーゼルスカブ タンパク質加水分解物
JP3046344B2 (ja) 1990-10-24 2000-05-29 塩野義製薬株式会社 新規プロテアーゼ
DK52393D0 (enExample) 1993-05-05 1993-05-05 Novo Nordisk As
DE69632630T2 (de) 1995-03-16 2005-05-25 Novozymes A/S Enzym mit aminopeptidaseactivität
EP2336331A1 (en) 1999-08-31 2011-06-22 Novozymes A/S Novel proteases and variants thereof
PL203212B1 (pl) 2000-02-08 2009-09-30 Dsm Ip Assets Bv Zastosowanie trwałej w kwasie proteazy w karmie zwierzęcej oraz w wytwarzaniu kompozycji do stosowania w karmie zwierzęcej, dodatek do karmy zwierzęcej, kompozycja karmy zwierzęcej i sposób obróbki białek roślinnych
CA2539693A1 (en) 2003-10-10 2005-04-21 Novozymes A/S Protease variants
US20070190130A1 (en) * 2006-02-16 2007-08-16 Mark William A Protein hydrolysate excipients
US9034402B2 (en) * 2007-04-16 2015-05-19 Solae, Llc Protein hydrolysate compositions having improved sensory characteristics and physical properties
EP2052734A1 (en) * 2007-10-26 2009-04-29 Universiteit Maastricht Proteins that stimulate the secretion of satiety hormones
CA2726110A1 (en) 2008-06-20 2009-12-23 Solae, Llc Protein hydrolysate compositions stable under acidic conditions

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005538704A (ja) * 2002-07-01 2005-12-22 ユニリーバー・ナームローゼ・ベンノートシヤープ 満腹誘導組成物
JP2006510367A (ja) * 2002-12-20 2006-03-30 ユニリーバー・ナームローゼ・ベンノートシヤープ 血糖調節組成物
WO2009101134A1 (fr) * 2008-02-12 2009-08-20 Compagnie Des Peches Saint Malo Sante Hydrolysat de proteines de poissons presentant une activite satietogene, compositions nutraceutiques et pharmacologiques comprenant un tel hydrolysat et procede d'obtention
WO2010078461A1 (en) * 2008-12-31 2010-07-08 Solae, Llc Protein hydrolysate compositions having enhanced cck releasing ability

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2020226046A1 (enExample) * 2019-05-08 2020-11-12
JP7722183B2 (ja) 2019-05-08 2025-08-13 不二製油株式会社 食肉加工食品及びその製造方法

Also Published As

Publication number Publication date
EP2677885A1 (en) 2014-01-01
BR112013021468A2 (pt) 2017-07-04
CN103561589A (zh) 2014-02-05
WO2012141795A1 (en) 2012-10-18
MX2013009772A (es) 2013-10-01
CA2825119A1 (en) 2012-10-18
US20130331315A1 (en) 2013-12-12

Similar Documents

Publication Publication Date Title
JP2014518542A (ja) 改善されたcckおよびglp−1放出活性を有するタンパク質加水分解組成物
EP2384125B1 (en) Protein hydrolysate compositions having enhanced cck releasing ability
Chandran et al. Sustainable plant protein: an up-to-date overview of sources, extraction techniques and utilization
Al‐Doury et al. Rice‐endosperm and rice‐bran proteins: A review
JP7783689B2 (ja) 改良された食品を得るためのペプチジルアルギニンデイミナーゼの使用
CN101558791A (zh) 一种基于双蛋白的多肽豆奶粉及其制备方法
CN102387711A (zh) 蛋白质水解产物组合物
US20140011742A1 (en) Bioactive Peptides and Proteins Containing Bioactive Peptides, their Uses and Processes for Making the Same
Anantharaman et al. Nutritional aspects of food proteins in relation to technology
Byanju et al. Protein-rich pulse ingredients: preparation, modification technologies and impact on important techno-functional and quality characteristics, and major food applications
EP3801068B1 (en) Modified rapeseed protein isolate
Segura-Campos et al. In vitro bioactivity, nutritional and sensory properties of semolina pasta added with hard-to-cook bean (Phaseolus vulgaris L.) protein hydrolysate
EP1641359B1 (en) Compositions and food products from oat
Howell Enzymatic Modifications
Winterová et al. Food allergies and intolerances-A review.
Anitha et al. A review on potato milk: A possible alternative for consumers allergic to cow milk proteins
Takacs et al. Mechanically deboned turkey meat with improved digestibility and biological value
Tu et al. Importance and nutritive value of plant proteins in human diet
Shanmugapriya et al. Hydrolysis of plant-based proteins
Joseph Protein quality of idli prepared from beans (Phaseolus vulgaris) and rice
Class et al. Patent application title: Bioactive Peptides and Proteins Containing Bioactive Peptides, their Uses and Processes for Making the Same Inventors: Jacqueline Sedman (Kirkland, CA) Ashraf A. Ismail (Westmount, CA) Ahmed I. Gomaa (Montreal, CA) Assignees: McGill University
MXPA01008531A (en) Nutritional composition intended for specific gastro-intestinal maturation in premature mammals

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150219

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20150219

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20160219

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20160224

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20161017