JP2014518232A5 - - Google Patents
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- Publication number
- JP2014518232A5 JP2014518232A5 JP2014517657A JP2014517657A JP2014518232A5 JP 2014518232 A5 JP2014518232 A5 JP 2014518232A5 JP 2014517657 A JP2014517657 A JP 2014517657A JP 2014517657 A JP2014517657 A JP 2014517657A JP 2014518232 A5 JP2014518232 A5 JP 2014518232A5
- Authority
- JP
- Japan
- Prior art keywords
- applicable
- acceptable
- vehicle
- stirring
- room temperature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 239000000203 mixture Substances 0.000 description 3
- 239000000546 pharmaceutical excipient Substances 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- MLDQJTXFUGDVEO-UHFFFAOYSA-N BAY-43-9006 Chemical compound C1=NC(C(=O)NC)=CC(OC=2C=CC(NC(=O)NC=3C=C(C(Cl)=CC=3)C(F)(F)F)=CC=2)=C1 MLDQJTXFUGDVEO-UHFFFAOYSA-N 0.000 description 1
- 239000005511 L01XE05 - Sorafenib Substances 0.000 description 1
- 241000036848 Porzana carolina Species 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229960003787 sorafenib Drugs 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 238000003260 vortexing Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11171715.3 | 2011-06-28 | ||
| EP11171715 | 2011-06-28 | ||
| EP12161989.4 | 2012-03-29 | ||
| EP12161989 | 2012-03-29 | ||
| PCT/EP2012/062354 WO2013000909A1 (en) | 2011-06-28 | 2012-06-26 | Topical ophthalmological pharmaceutical composition containing sorafenib |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014518232A JP2014518232A (ja) | 2014-07-28 |
| JP2014518232A5 true JP2014518232A5 (cg-RX-API-DMAC7.html) | 2014-09-04 |
Family
ID=46397246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014517657A Ceased JP2014518232A (ja) | 2011-06-28 | 2012-06-26 | ソラフェニブを含有する眼科用局所医薬組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20140235678A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2726057A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2014518232A (cg-RX-API-DMAC7.html) |
| CN (1) | CN103764118A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2840491A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013000909A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2581843C (en) | 2004-09-29 | 2012-05-15 | Bayer Healthcare Ag | Thermodynamically stable form of bay 43-9006 tosylate |
| CN104688697A (zh) | 2005-03-07 | 2015-06-10 | 拜尔健康护理有限责任公司 | 用于治疗癌症的包含ω-羧芳基取代的二苯基脲的药物组合物 |
| AR081060A1 (es) | 2010-04-15 | 2012-06-06 | Bayer Schering Pharma Ag | Procedimiento para preparar 4-{4-[({[4-cloro-3-(trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}-n-metilpiridin-2-carboxamida |
| US9206423B2 (en) * | 2012-12-30 | 2015-12-08 | The Regents Of The University Of California | Methods of modulating compliance of the trabecular meshwork |
| US8901144B2 (en) | 2013-02-07 | 2014-12-02 | Scifluor Life Sciences, Llc | Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives |
| EP2953948B1 (en) | 2013-02-07 | 2017-09-27 | Scifluor Life Sciences, Inc | Fluorinated integrin antagonists |
| US11136625B2 (en) | 2013-08-28 | 2021-10-05 | Crown Bioscience, Inc. (Taicang) | Gene expression signatures predictive of subject response to a multi-kinase inhibitor and methods of using the same |
| PL3203989T3 (pl) | 2014-10-09 | 2020-06-29 | Distretto Tecnologico Sicilia Micro E Nano Sistemi S.C.A.R.L. | Nanostrukturalne preparaty do dostarczania sylibininy i innych składników czynnych do leczenia chorób oczu |
| CN114805342A (zh) | 2015-02-19 | 2022-07-29 | 赛弗卢尔生命科学公司 | 氟化四氢萘啶基壬酸衍生物及其用途 |
| MX385405B (es) * | 2015-05-05 | 2025-03-18 | Eyepoint Pharmaceuticals Us Inc | Composición inyectable en el vítreo de un ojo que comprende un inhibidor de cinasa y el uso de la misma para tratar una enfermedad ocular. |
| EP4335418A3 (en) | 2015-06-06 | 2024-05-22 | Cloudbreak Therapeutics, LLC | Compositions and methods for treating pterygium |
| TWI664965B (zh) * | 2015-06-22 | 2019-07-11 | 新源生物科技股份有限公司 | 酪胺酸激酶抑制劑之眼用調配物、其使用方法、及其製備方法 |
| ES2886542T3 (es) | 2016-05-25 | 2021-12-20 | Santen Pharmaceutical Co Ltd | Uso de sirolimus para tratar la degeneración macular asociada con la edad exudativa con edema persistente |
| KR20240052865A (ko) | 2016-06-02 | 2024-04-23 | 에이디에스 테라퓨틱스 엘엘씨 | 녹내장 수술 성공을 개선하기 위해 닌테다닙을 사용하는 조성물 및 방법 |
| CN114288242B (zh) * | 2022-01-14 | 2023-05-23 | 中国药科大学 | 一种索拉非尼纳米混悬滴眼液及其制备方法 |
| WO2025169089A1 (en) | 2024-02-05 | 2025-08-14 | Sun Pharmaceutical Industries Limited | Ophthalmic compositions of tyrosine kinase inhibitors and their uses |
| CN117982434A (zh) * | 2024-02-22 | 2024-05-07 | 中国药科大学 | 一种治疗湿性年龄相关性黄斑病变的对甲苯磺酸索拉非尼聚乳酸微球 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1140840B1 (en) | 1999-01-13 | 2006-03-22 | Bayer Pharmaceuticals Corp. | -g(v)-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| ES2305808T3 (es) | 2003-05-20 | 2008-11-01 | Bayer Healthcare Llc | Diarilureas con actividad inhibidora de quinasas. |
| CA2581843C (en) | 2004-09-29 | 2012-05-15 | Bayer Healthcare Ag | Thermodynamically stable form of bay 43-9006 tosylate |
| PL1885336T3 (pl) | 2005-05-10 | 2009-08-31 | Alcon Inc | Kompozycja w postaci zawiesiny zawierająca substancję aktywną, poloksamerowy lub meroksapolowy surfaktant i glikol oraz zastosowanie kompozycji do wytwarzania leku do leczenia chorób oczu |
| US20060292203A1 (en) | 2005-06-08 | 2006-12-28 | Targegen, Inc. | Methods and compositions for the treatment of ocular disorders |
| SI1968594T1 (sl) | 2005-11-29 | 2011-01-31 | Glaxosmithkline Llc | Tretma okularnih neovaskularnih motenj, kot makularne degeneracije, angiodnih prog. uveitisa in makularnega edema |
| CA2633411A1 (en) * | 2005-12-15 | 2007-06-21 | Bayer Healthcare Ag | Diaryl ureas for treating inflammatory skin, eye and/or ear diseases |
| US20070149593A1 (en) | 2005-12-23 | 2007-06-28 | Alcon, Inc. | PHARMACEUTICAL FORMULATION FOR DELIVERY OF RECEPTOR TYROSINE KINASE INHIBITING (RTKi) COMPOUNDS TO THE EYE |
| WO2008027341A2 (en) | 2006-08-30 | 2008-03-06 | Merck & Co., Inc. | Topical ophthalmic formulations |
| EP2156834A1 (en) * | 2008-08-08 | 2010-02-24 | S.I.F.I - Società Industria Farmaceutica Italiana - S.P.A. | Ophthalmic pharmaceutical compositions comprising Sorafenib for the treatment of neoangiogenic pathologies of the eye |
| EP3028707A1 (en) | 2009-05-01 | 2016-06-08 | Ophthotech Corporation | Methods for treating or preventing ophthalmological diseases |
| JP2012533562A (ja) | 2009-07-16 | 2012-12-27 | グラクソ ウェルカム マニュファクチュアリング ピーティーイー リミテッド | 治療法 |
-
2012
- 2012-06-26 JP JP2014517657A patent/JP2014518232A/ja not_active Ceased
- 2012-06-26 EP EP12730512.6A patent/EP2726057A1/en not_active Withdrawn
- 2012-06-26 WO PCT/EP2012/062354 patent/WO2013000909A1/en not_active Ceased
- 2012-06-26 CN CN201280031848.XA patent/CN103764118A/zh active Pending
- 2012-06-26 US US14/129,557 patent/US20140235678A1/en not_active Abandoned
- 2012-06-26 CA CA2840491A patent/CA2840491A1/en not_active Abandoned
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