JP2014517751A5 - - Google Patents
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- Publication number
- JP2014517751A5 JP2014517751A5 JP2014510437A JP2014510437A JP2014517751A5 JP 2014517751 A5 JP2014517751 A5 JP 2014517751A5 JP 2014510437 A JP2014510437 A JP 2014510437A JP 2014510437 A JP2014510437 A JP 2014510437A JP 2014517751 A5 JP2014517751 A5 JP 2014517751A5
- Authority
- JP
- Japan
- Prior art keywords
- scaffold
- plla
- stent
- kda
- radiation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920000642 polymer Polymers 0.000 claims description 40
- JVTAAEKCZFNVCJ-REOHCLBHSA-N L-lactic acid Chemical compound C[C@H](O)C(O)=O JVTAAEKCZFNVCJ-REOHCLBHSA-N 0.000 claims description 39
- 238000000034 method Methods 0.000 claims description 36
- 238000004519 manufacturing process Methods 0.000 claims description 25
- 239000000178 monomer Substances 0.000 claims description 23
- 229920001432 poly(L-lactide) Polymers 0.000 claims description 22
- 230000005855 radiation Effects 0.000 claims description 22
- 238000006731 degradation reaction Methods 0.000 claims description 19
- 230000015556 catabolic process Effects 0.000 claims description 18
- 230000001954 sterilising effect Effects 0.000 claims description 14
- 238000004659 sterilization and disinfection Methods 0.000 claims description 12
- 238000000354 decomposition reaction Methods 0.000 claims description 10
- 206010073306 Exposure to radiation Diseases 0.000 claims description 7
- 230000007062 hydrolysis Effects 0.000 claims description 7
- 238000006460 hydrolysis reaction Methods 0.000 claims description 7
- 229920005989 resin Polymers 0.000 claims description 5
- 239000011347 resin Substances 0.000 claims description 5
- 238000002788 crimping Methods 0.000 claims description 4
- 206010003549 asthenia Diseases 0.000 claims description 3
- 239000002952 polymeric resin Substances 0.000 claims description 3
- 229920003002 synthetic resin Polymers 0.000 claims description 3
- 229920001244 Poly(D,L-lactide) Polymers 0.000 claims description 2
- 239000011248 coating agent Substances 0.000 claims description 2
- 238000000576 coating method Methods 0.000 claims description 2
- 230000000593 degrading effect Effects 0.000 claims description 2
- JJTUDXZGHPGLLC-IMJSIDKUSA-N 4511-42-6 Chemical compound C[C@@H]1OC(=O)[C@H](C)OC1=O JJTUDXZGHPGLLC-IMJSIDKUSA-N 0.000 claims 6
- 238000003698 laser cutting Methods 0.000 claims 1
- 238000002513 implantation Methods 0.000 description 3
- 238000001125 extrusion Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000006116 polymerization reaction Methods 0.000 description 2
- 229920001002 functional polymer Polymers 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/104,732 US8834776B2 (en) | 2011-05-10 | 2011-05-10 | Control of degradation profile of bioabsorbable poly(l-lactide) scaffold |
| US13/104,732 | 2011-05-10 | ||
| PCT/US2012/037104 WO2012154842A2 (en) | 2011-05-10 | 2012-05-09 | Control of degradation profile of bioabsorbable poly(l-lactide) scaffold |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014517751A JP2014517751A (ja) | 2014-07-24 |
| JP2014517751A5 true JP2014517751A5 (enExample) | 2015-07-02 |
| JP6421034B2 JP6421034B2 (ja) | 2018-11-07 |
Family
ID=46147052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014510437A Expired - Fee Related JP6421034B2 (ja) | 2011-05-10 | 2012-05-09 | 生体吸収性ポリ（ｌ−ラクチド）スキャフォールドの分解プロファイルの管理 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8834776B2 (enExample) |
| EP (1) | EP2707046B1 (enExample) |
| JP (1) | JP6421034B2 (enExample) |
| CN (2) | CN103764183B (enExample) |
| WO (1) | WO2012154842A2 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8814930B2 (en) | 2007-01-19 | 2014-08-26 | Elixir Medical Corporation | Biodegradable endoprosthesis and methods for their fabrication |
| US8889823B2 (en) | 2009-07-21 | 2014-11-18 | Abbott Cardiovascular Systems Inc. | Method to make poly(L-lactide) stent with tunable degradation rate |
| US9889238B2 (en) | 2009-07-21 | 2018-02-13 | Abbott Cardiovascular Systems Inc. | Biodegradable stent with adjustable degradation rate |
| US8207240B2 (en) * | 2009-09-14 | 2012-06-26 | Abbott Cardiovascular Systems Inc | Method to minimize molecular weight drop of poly(L-lactide) stent during processing |
| US8841412B2 (en) | 2011-08-11 | 2014-09-23 | Abbott Cardiovascular Systems Inc. | Controlling moisture in and plasticization of bioresorbable polymer for melt processing |
| US9408952B2 (en) * | 2011-11-30 | 2016-08-09 | Abbott Cardiovascular Systems Inc. | Pediatric application of bioabsorbable polymer stents in infants and children with congenital heart defects |
| US9078740B2 (en) | 2013-01-21 | 2015-07-14 | Howmedica Osteonics Corp. | Instrumentation and method for positioning and securing a graft |
| MY195227A (en) * | 2013-07-09 | 2023-01-11 | National Univ Corporation Nagoya Institute Technology | Bone Defect Filling Material, and Production Method Therefor |
| US10143572B2 (en) | 2013-09-04 | 2018-12-04 | Abbott Cardiovascular Systems Inc. | Assessment of a drug eluting bioresorbable vascular scaffold |
| JP6356262B2 (ja) | 2014-04-08 | 2018-07-11 | ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． | ステント |
| US9855156B2 (en) * | 2014-08-15 | 2018-01-02 | Elixir Medical Corporation | Biodegradable endoprostheses and methods of their fabrication |
| US9730819B2 (en) | 2014-08-15 | 2017-08-15 | Elixir Medical Corporation | Biodegradable endoprostheses and methods of their fabrication |
| US9480588B2 (en) | 2014-08-15 | 2016-11-01 | Elixir Medical Corporation | Biodegradable endoprostheses and methods of their fabrication |
| GB2546319B (en) * | 2016-01-15 | 2019-07-03 | Cook Medical Technologies Llc | Coated medical device and method of coating such a device |
| US11622872B2 (en) | 2016-05-16 | 2023-04-11 | Elixir Medical Corporation | Uncaging stent |
| ES2873887T3 (es) | 2016-05-16 | 2021-11-04 | Elixir Medical Corp | Liberación de stent |
| JP7128120B2 (ja) | 2016-06-23 | 2022-08-30 | ポリ－メド インコーポレイテッド | 生分解が管理された医療デバイス |
| CN106073943B (zh) * | 2016-07-19 | 2019-06-04 | 青岛三帝生物科技有限公司 | 基于3d打印的防渗漏乳房假体成型方法和乳房假体 |
| US10966848B2 (en) | 2016-12-29 | 2021-04-06 | Boston Scientific Scimed, Inc. | Medical devices formed from polymer filaments |
| CN115219655A (zh) * | 2022-06-14 | 2022-10-21 | 南京浩衍鼎业科技技术有限公司 | 一种聚合物产品降解速率控制方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6206883B1 (en) | 1999-03-05 | 2001-03-27 | Stryker Technologies Corporation | Bioabsorbable materials and medical devices made therefrom |
| DK2298366T3 (da) | 2000-03-13 | 2012-11-26 | Kyoto Iryo Sekkei Kk | Lineært materiale til intravaskulær stent og intravaskulær stent med anvendelse deraf |
| WO2001095834A1 (en) * | 2000-06-13 | 2001-12-20 | Scimed Life Systems, Inc. | Disintegrating stent and method of making same |
| US20030069629A1 (en) | 2001-06-01 | 2003-04-10 | Jadhav Balkrishna S. | Bioresorbable medical devices |
| GB0116341D0 (en) | 2001-07-04 | 2001-08-29 | Smith & Nephew | Biodegradable polymer systems |
| US8747879B2 (en) | 2006-04-28 | 2014-06-10 | Advanced Cardiovascular Systems, Inc. | Method of fabricating an implantable medical device to reduce chance of late inflammatory response |
| US7731890B2 (en) | 2006-06-15 | 2010-06-08 | Advanced Cardiovascular Systems, Inc. | Methods of fabricating stents with enhanced fracture toughness |
| US8394446B2 (en) * | 2005-07-25 | 2013-03-12 | Abbott Cardiovascular Systems Inc. | Methods of providing antioxidants to implantable medical devices |
| US20070179276A1 (en) | 2006-01-31 | 2007-08-02 | Purac Biochem Bv | Method for the purification of resorbable polymers from residual monomers |
| US20070203564A1 (en) | 2006-02-28 | 2007-08-30 | Boston Scientific Scimed, Inc. | Biodegradable implants having accelerated biodegradation properties in vivo |
| US20090076594A1 (en) * | 2006-03-14 | 2009-03-19 | Patrick Sabaria | Method of monitoring positioning of polymer stents |
| US7794776B1 (en) | 2006-06-29 | 2010-09-14 | Abbott Cardiovascular Systems Inc. | Modification of polymer stents with radiation |
| US7794495B2 (en) * | 2006-07-17 | 2010-09-14 | Advanced Cardiovascular Systems, Inc. | Controlled degradation of stents |
| US8388673B2 (en) | 2008-05-02 | 2013-03-05 | Abbott Cardiovascular Systems Inc. | Polymeric stent |
| US8802126B2 (en) * | 2008-06-30 | 2014-08-12 | Abbott Cardiovascular Systems Inc. | Polyester implantable medical device with controlled in vivo biodegradability |
| US8889823B2 (en) | 2009-07-21 | 2014-11-18 | Abbott Cardiovascular Systems Inc. | Method to make poly(L-lactide) stent with tunable degradation rate |
| US9889238B2 (en) | 2009-07-21 | 2018-02-13 | Abbott Cardiovascular Systems Inc. | Biodegradable stent with adjustable degradation rate |
| US8685433B2 (en) | 2010-03-31 | 2014-04-01 | Abbott Cardiovascular Systems Inc. | Absorbable coating for implantable device |
| US8613880B2 (en) | 2010-04-21 | 2013-12-24 | Abbott Cardiovascular Systems Inc. | Post electron beam conditioning of polymeric medical devices |
| US8496865B2 (en) | 2010-10-15 | 2013-07-30 | Abbott Cardiovascular Systems Inc. | Method to minimize chain scission and monomer generation in processing of poly(L-lactide) stent |
-
2011
- 2011-05-10 US US13/104,732 patent/US8834776B2/en active Active
-
2012
- 2012-05-09 WO PCT/US2012/037104 patent/WO2012154842A2/en not_active Ceased
- 2012-05-09 JP JP2014510437A patent/JP6421034B2/ja not_active Expired - Fee Related
- 2012-05-09 CN CN201280028649.3A patent/CN103764183B/zh active Active
- 2012-05-09 CN CN201610524672.1A patent/CN106075607B/zh active Active
- 2012-05-09 EP EP12722605.8A patent/EP2707046B1/en not_active Not-in-force
-
2014
- 2014-08-14 US US14/460,199 patent/US20140353877A1/en not_active Abandoned
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