JP2014511393A - イソインドリン化合物を用いた疾患の治療方法 - Google Patents
イソインドリン化合物を用いた疾患の治療方法 Download PDFInfo
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- JP2014511393A JP2014511393A JP2013557763A JP2013557763A JP2014511393A JP 2014511393 A JP2014511393 A JP 2014511393A JP 2013557763 A JP2013557763 A JP 2013557763A JP 2013557763 A JP2013557763 A JP 2013557763A JP 2014511393 A JP2014511393 A JP 2014511393A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
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- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161449716P | 2011-03-07 | 2011-03-07 | |
| US61/449,716 | 2011-03-07 | ||
| PCT/US2012/027368 WO2012121988A2 (en) | 2011-03-07 | 2012-03-02 | Methods for treating diseases using isoindoline compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014511393A true JP2014511393A (ja) | 2014-05-15 |
| JP2014511393A5 JP2014511393A5 (enExample) | 2015-04-16 |
Family
ID=45852726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013557763A Pending JP2014511393A (ja) | 2011-03-07 | 2012-03-02 | イソインドリン化合物を用いた疾患の治療方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9387195B2 (enExample) |
| EP (2) | EP2683376B1 (enExample) |
| JP (1) | JP2014511393A (enExample) |
| ES (2) | ES2711100T3 (enExample) |
| WO (1) | WO2012121988A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020505469A (ja) * | 2017-01-27 | 2020-02-20 | サルドバーヴァ フォーミュレーションズ プライベート リミテッドSarudbhava Formulations Private Limited | 治療用アプレミラスト局所組成物 |
| WO2023120466A1 (ja) * | 2021-12-23 | 2023-06-29 | 沢井製薬株式会社 | アプレミラスト水和物含有製剤 |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2884454C (en) * | 2012-10-11 | 2021-07-27 | Nerre Therapeutics Limited | Orvepitant and uses thereof |
| EP3010490A1 (en) * | 2013-06-17 | 2016-04-27 | Celgene Corporation | Tablet formulations of (+)-2-[1 -(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione |
| RU2538615C1 (ru) * | 2013-08-20 | 2015-01-10 | Общество с ограниченной ответственностью "УНИФАРМ" (ООО "УНИФАРМ"). | Средство для профилактики и лечения простатита и аденомы предстательной железы |
| CN105669478A (zh) * | 2014-11-17 | 2016-06-15 | 重庆医药工业研究院有限责任公司 | 一种制备3-氨基邻苯二甲酸及其衍生物的方法 |
| AU2015371308A1 (en) | 2014-12-23 | 2017-08-03 | Intellectual Property Associates, Llc | Methods and formulations for transdermal administration |
| WO2017085568A1 (en) * | 2015-11-19 | 2017-05-26 | Alembic Pharmaceuticals Limited | An improved process and novel polymorphic form of apremilast |
| CN105388237B (zh) * | 2015-12-28 | 2017-02-01 | 成都百裕金阁莱药业有限公司 | 阿普斯特中3‑乙酰氨基邻苯二甲酸的检测方法 |
| EP3435973B1 (en) * | 2016-03-30 | 2023-11-01 | Sarudbhava Formulations Private Limited | Apremilast pharmaceutical compositions |
| JP6827113B2 (ja) * | 2017-01-21 | 2021-02-10 | 広州白雲山漢方現代薬業有限公司Guangzhou Hanfang Pharmaceutical Co.,Ltd. | シェーグレン症候群の治療におけるペオニフロリン−6’−o−ベンゼンスルホン酸の使用 |
| JP2020534285A (ja) | 2017-09-15 | 2020-11-26 | アンパサンド バイオファーマシューティカルズ インコーポレイテッドAmpersand Biopharmaceuticals Inc. | 投与および処置の方法 |
| US20240252426A1 (en) * | 2018-09-21 | 2024-08-01 | Apramitha Innovations Private Limited | Improved and stable apremilast pharmaceutical compositions |
| BR112021013174A2 (pt) | 2019-01-11 | 2021-11-03 | Novartis Ag | Anticorpos anti-cd40 para uso no tratamento da hidradenite supurativa |
| CN115068406A (zh) * | 2021-03-12 | 2022-09-20 | 浙江万晟药业有限公司 | 一种用于治疗斑秃的阿普斯特凝胶及其制备工艺 |
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| JP2004500346A (ja) * | 1999-11-12 | 2004-01-08 | セルジーン コーポレイション | 薬剤活性のあるイソインドリン誘導体 |
| JP2005525386A (ja) * | 2002-03-20 | 2005-08-25 | セルジーン・コーポレーション | (+)−2−[1−(3−エトキシ−4−メトキシフェニル)−2−メチルスルホニルエチル]−4−アセチルアミノイソインドリン−1,3−ジオン、その使用方法及び組成物 |
| JP2005529930A (ja) * | 2002-05-28 | 2005-10-06 | アルタナ ファルマ アクチエンゲゼルシャフト | 局所適用可能な薬剤学的製剤 |
| JP2006511479A (ja) * | 2002-09-27 | 2006-04-06 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 3,4−二置換ピロールおよび炎症性疾患の治療におけるこれらの使用 |
| JP2007536222A (ja) * | 2004-05-05 | 2007-12-13 | セルジーン・コーポレーション | 癌及び他の疾患を治療及び管理するための選択的サイトカイン阻害薬を用いた方法及び組成物 |
| JP2008518891A (ja) * | 2004-11-02 | 2008-06-05 | スイッチ バイオテック アーゲー | Tリンパ球の増殖および/またはケラチノサイトの過剰増殖を特徴とする疾患、特にアトピー性皮膚炎および乾癬を処置するための、ピルリンドールの使用 |
| JP2008523102A (ja) * | 2004-12-13 | 2008-07-03 | セルジーン・コーポレーション | Pde4モジュレーターを含有する組成物及び気道炎症の治療又は予防のためのそれらの使用 |
| JP2009522289A (ja) * | 2005-12-29 | 2009-06-11 | セルジーン・コーポレーション | アミノイソインドリン化合物を使用した皮膚狼瘡治療方法 |
| WO2009120167A1 (en) * | 2008-03-27 | 2009-10-01 | Celgene Corporation | Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof |
| WO2010069322A1 (en) * | 2008-12-19 | 2010-06-24 | Leo Pharma A/S | Triazolopyridines as phosphodiesterase inhibitors for treatment of dermal diseases |
| JP2010523725A (ja) * | 2007-04-16 | 2010-07-15 | レオ ファーマ アクティーゼルスカブ | 皮膚疾患処置用ホスホジエステラーゼ阻害剤としてのトリアゾロピリジン |
| WO2010091894A2 (en) * | 2009-02-16 | 2010-08-19 | Giuliani International Limited | Methods of treating hair related conditions |
| WO2011001212A1 (en) * | 2009-06-30 | 2011-01-06 | Piramal Life Sciences Limited | Imidazo [4,5-c]quinoline derivatives and their use in the treatment of tumors and/or inflammation |
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| CN101745112A (zh) | 2002-07-19 | 2010-06-23 | 艾博特生物技术有限公司 | TNFα相关疾病的治疗 |
| DE102004046235A1 (de) * | 2004-09-22 | 2006-03-30 | Altana Pharma Ag | Arzneimittelzubereitung |
| WO2008013791A2 (en) * | 2006-07-24 | 2008-01-31 | University Of Delaware | Pan-antagonists for the androgen receptor and androgen receptor mutants associated with anti-androgen withdrawal |
| EP2498753B1 (en) * | 2009-11-10 | 2019-03-06 | Celgene Corporation | Nanosuspension of a poorly soluble drug made by microfluidization process |
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2012
- 2012-03-02 ES ES12709437T patent/ES2711100T3/es active Active
- 2012-03-02 EP EP12709437.3A patent/EP2683376B1/en active Active
- 2012-03-02 WO PCT/US2012/027368 patent/WO2012121988A2/en not_active Ceased
- 2012-03-02 ES ES17208060T patent/ES2868231T3/es active Active
- 2012-03-02 JP JP2013557763A patent/JP2014511393A/ja active Pending
- 2012-03-02 US US14/003,750 patent/US9387195B2/en active Active
- 2012-03-02 EP EP17208060.8A patent/EP3320902B1/en not_active Revoked
Patent Citations (13)
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| WO2023120466A1 (ja) * | 2021-12-23 | 2023-06-29 | 沢井製薬株式会社 | アプレミラスト水和物含有製剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20140187599A1 (en) | 2014-07-03 |
| WO2012121988A3 (en) | 2013-01-10 |
| EP2683376A2 (en) | 2014-01-15 |
| WO2012121988A2 (en) | 2012-09-13 |
| ES2868231T3 (es) | 2021-10-21 |
| ES2711100T3 (es) | 2019-04-30 |
| EP3320902A1 (en) | 2018-05-16 |
| EP2683376B1 (en) | 2018-11-28 |
| EP3320902B1 (en) | 2021-02-17 |
| US9387195B2 (en) | 2016-07-12 |
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