JP2014509648A

JP2014509648A - （α−置換シクロアルキルアミノ及びヘテロシクリルアミノ）ピリミジニル及び１，３，５−トリアジニルベンズイミダゾール、その医薬組成物、並びに増殖性疾患の治療におけるそれらの使用

（α−置換シクロアルキルアミノ及びヘテロシクリルアミノ）ピリミジニル及び１，３，５−トリアジニルベンズイミダゾール、その医薬組成物、並びに増殖性疾患の治療におけるそれらの使用 Download PDF

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Publication number: JP2014509648A
Authority: JP; Japan
Prior art keywords: compound; certain embodiments; substituents; optionally substituted; alkyl
Prior art date: 2011-03-28
Legal status : Pending

Application number

JP2014502672A

Other languages

English (en)

Japanese (ja)

Other versions

JP2014509648A5 (enExample

Inventor

ブロウンエス．ダビド

ジェイ．マトトヘウスダビド

Original Assignee

メイプハルマ，インコーポレーテッド

Priority date

2011-03-28

Filing date

2012-03-27

Publication date

2014-04-21

2012-03-27 Application filed by メイプハルマ，インコーポレーテッド filed Critical メイプハルマ，インコーポレーテッド

2014-04-21 Publication of JP2014509648A publication Critical patent/JP2014509648A/ja

2015-05-14 Publication of JP2014509648A5 publication Critical patent/JP2014509648A5/ja

Status Pending legal-status Critical Current

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239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 87
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CAWUKUTZZCUVSH-UHFFFAOYSA-N 2-(1,3,5-triazin-2-yl)-1h-benzimidazole Chemical class N=1C2=CC=CC=C2NC=1C1=NC=NC=N1 CAWUKUTZZCUVSH-UHFFFAOYSA-N 0.000 title abstract description 3
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HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 claims description 50
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