JP2014508799A5 - - Google Patents

Download PDF

Info

Publication number
JP2014508799A5
JP2014508799A5 JP2014500487A JP2014500487A JP2014508799A5 JP 2014508799 A5 JP2014508799 A5 JP 2014508799A5 JP 2014500487 A JP2014500487 A JP 2014500487A JP 2014500487 A JP2014500487 A JP 2014500487A JP 2014508799 A5 JP2014508799 A5 JP 2014508799A5
Authority
JP
Japan
Prior art keywords
composition
cells
stromal cells
adherent stromal
effective amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014500487A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014508799A (ja
JP6030114B2 (ja
Filing date
Publication date
Priority claimed from US13/069,130 external-priority patent/US20110171182A1/en
Priority claimed from US13/161,334 external-priority patent/US20110293583A1/en
Application filed filed Critical
Priority claimed from PCT/IB2012/000664 external-priority patent/WO2012127320A1/en
Publication of JP2014508799A publication Critical patent/JP2014508799A/ja
Publication of JP2014508799A5 publication Critical patent/JP2014508799A5/ja
Application granted granted Critical
Publication of JP6030114B2 publication Critical patent/JP6030114B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2014500487A 2011-03-22 2012-03-22 放射線照射または化学物質による傷害を治療するための方法 Active JP6030114B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US13/069,130 2011-03-22
US13/069,130 US20110171182A1 (en) 2006-03-23 2011-03-22 Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
US201161497400P 2011-06-15 2011-06-15
US61/497,400 2011-06-15
US13/161,334 US20110293583A1 (en) 2006-03-23 2011-06-15 Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
US13/161,334 2011-06-15
US201261595485P 2012-02-06 2012-02-06
US61/595,485 2012-02-06
PCT/IB2012/000664 WO2012127320A1 (en) 2011-03-22 2012-03-22 Methods for treating radiation or chemical injury

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016205482A Division JP6266726B2 (ja) 2011-03-22 2016-10-19 放射線照射または化学物質による傷害を治療するための方法

Publications (3)

Publication Number Publication Date
JP2014508799A JP2014508799A (ja) 2014-04-10
JP2014508799A5 true JP2014508799A5 (enExample) 2015-11-26
JP6030114B2 JP6030114B2 (ja) 2016-11-24

Family

ID=45976430

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2014500487A Active JP6030114B2 (ja) 2011-03-22 2012-03-22 放射線照射または化学物質による傷害を治療するための方法
JP2016205482A Active JP6266726B2 (ja) 2011-03-22 2016-10-19 放射線照射または化学物質による傷害を治療するための方法
JP2017244534A Active JP6548714B2 (ja) 2011-03-22 2017-12-20 放射線照射または化学物質による傷害を治療するための方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2016205482A Active JP6266726B2 (ja) 2011-03-22 2016-10-19 放射線照射または化学物質による傷害を治療するための方法
JP2017244534A Active JP6548714B2 (ja) 2011-03-22 2017-12-20 放射線照射または化学物質による傷害を治療するための方法

Country Status (7)

Country Link
US (2) US10722541B2 (enExample)
EP (2) EP2689008B1 (enExample)
JP (3) JP6030114B2 (enExample)
KR (2) KR101903339B1 (enExample)
HK (1) HK1244502A1 (enExample)
IL (3) IL228470A (enExample)
WO (1) WO2012127320A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101490449B1 (ko) * 2006-03-23 2015-02-05 플루리스템 리미티드 세포 증식 방법 및 세포의 용도 및 치료를 위해 그 세포에 의해 제조되는 조절된 배지
US9725689B2 (en) 2010-10-08 2017-08-08 Terumo Bct, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
KR101903339B1 (ko) * 2011-03-22 2018-10-01 플루리스템 리미티드 방사선 또는 화학적 손상을 치료하는 방법
EP2731440A4 (en) * 2011-07-15 2015-04-29 Anthrogenesis Corp RADIATION LESSON TREATMENT USING ADHESENT CELLS DERIVED FROM AMNIOS
JP2015521630A (ja) * 2012-06-26 2015-07-30 ラスティー プロパティー ホールディングス プロプライエタリー リミテッド 頭痛の頻度および／または重症度を下げるための組成物および方法
EP3068867B1 (en) 2013-11-16 2018-04-18 Terumo BCT, Inc. Expanding cells in a bioreactor
US11008547B2 (en) 2014-03-25 2021-05-18 Terumo Bct, Inc. Passive replacement of media
EP3198006B1 (en) 2014-09-26 2021-03-24 Terumo BCT, Inc. Scheduled feed
CN107864627A (zh) * 2015-03-23 2018-03-30 普拉里斯坦有限公司 包含粘附基质细胞的方法和组合物
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
WO2017205667A1 (en) 2016-05-25 2017-11-30 Terumo Bct, Inc. Cell expansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US10932711B2 (en) 2017-02-27 2021-03-02 Payman Sadeghi Method and system for neurohydrodissection
US10456419B2 (en) 2017-02-27 2019-10-29 Payman Sadeghi Method for treating migraine headaches
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
JP7393945B2 (ja) 2017-03-31 2023-12-07 テルモ ビーシーティー、インコーポレーテッド 細胞増殖
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
CA3125311A1 (en) * 2019-03-27 2020-10-01 Pluristem Ltd. Methods and compositions for aesthetic and cosmetic treatment and stimulating hair growth
EP4164706A1 (en) 2019-12-04 2023-04-19 Centre Hospitalier Universitaire Vaudois (CHUV) Device and process for tissue-engineering and regenerative medicine
EP4314244B1 (en) 2021-03-23 2025-07-23 Terumo BCT, Inc. Cell capture and expansion
US12152699B2 (en) 2022-02-28 2024-11-26 Terumo Bct, Inc. Multiple-tube pinch valve assembly
US20230293598A1 (en) * 2022-03-15 2023-09-21 Narkeshyo LLC Prevention of radiation exposure associated pathology by treatment with umbilical cord derived regenerative cells
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device

Family Cites Families (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154600B (nl) 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
NL154599B (nl) 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
US3901654A (en) 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
US3853987A (en) 1971-09-01 1974-12-10 W Dreyer Immunological reagent and radioimmuno assay
US3867517A (en) 1971-12-21 1975-02-18 Abbott Lab Direct radioimmunoassay for antigens and their antibodies
NL171930C (nl) 1972-05-11 1983-06-01 Akzo Nv Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.
US3850578A (en) 1973-03-12 1974-11-26 H Mcconnell Process for assaying for biologically active molecules
US3935074A (en) 1973-12-17 1976-01-27 Syva Company Antibody steric hindrance immunoassay with two antibodies
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4034074A (en) 1974-09-19 1977-07-05 The Board Of Trustees Of Leland Stanford Junior University Universal reagent 2-site immunoradiometric assay using labelled anti (IgG)
US3984533A (en) 1975-11-13 1976-10-05 General Electric Company Electrophoretic method of detecting antigen-antibody reaction
US4098876A (en) 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4879219A (en) 1980-09-19 1989-11-07 General Hospital Corporation Immunoassay utilizing monoclonal high affinity IgM antibodies
US5011771A (en) 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
US4666828A (en) 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4801531A (en) 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
US5266476A (en) 1985-06-18 1993-11-30 Yeda Research & Development Co., Ltd. Fibrous matrix for in vitro cell cultivation
US4963489A (en) 1987-04-14 1990-10-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5902741A (en) 1986-04-18 1999-05-11 Advanced Tissue Sciences, Inc. Three-dimensional cartilage cultures
US5272057A (en) 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5192659A (en) 1989-08-25 1993-03-09 Genetype Ag Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US6010696A (en) 1990-11-16 2000-01-04 Osiris Therapeutics, Inc. Enhancing hematopoietic progenitor cell engraftment using mesenchymal stem cells
US5281521A (en) 1992-07-20 1994-01-25 The Trustees Of The University Of Pennsylvania Modified avidin-biotin technique
US5629186A (en) 1994-04-28 1997-05-13 Lockheed Martin Corporation Porous matrix and method of its production
US5736396A (en) 1995-01-24 1998-04-07 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation
US6132463A (en) 1995-05-19 2000-10-17 Etex Corporation Cell seeding of ceramic compositions
CA2237890C (en) 1995-11-16 2011-03-29 Case Western Reserve University In vitro chondrogenic induction of human mesenchymal stem cells
US6291240B1 (en) 1998-01-29 2001-09-18 Advanced Tissue Sciences, Inc. Cells or tissues with increased protein factors and methods of making and using same
DE69922933T2 (de) 1998-03-13 2005-12-29 Osiris Therapeutics, Inc. Anwendungen für humane nicht autologe, mesenchymale stammzellen
EP1064353B1 (en) 1998-03-18 2002-11-06 Massachusetts Institute Of Technology Vascularized perfused microtissue/micro-organ arrays
CA2348770A1 (en) 1998-10-26 2000-05-04 Philadelphia Health & Education Corporation Stromal cell use
US6153432A (en) 1999-01-29 2000-11-28 Zen-Bio, Inc Methods for the differentiation of human preadipocytes into adipocytes
MXPA01007820A (es) 1999-02-04 2003-06-19 Technion Res & Dev Foundation Metodo y aparato para mantenimiento y expansion de celulas de tallo hemopoyeticas y/o celulas progenitoras.
RU2306335C2 (ru) 1999-03-10 2007-09-20 Юниверсити Оф Питтсбург Оф Дзе Коммонвелт Систем Оф Хайер Эдьюкейшн Стволовые клетки и решетки, полученные из жировой ткани
US6555374B1 (en) 1999-08-19 2003-04-29 Artecel Sciences, Inc. Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof
US20030161817A1 (en) 2001-03-28 2003-08-28 Young Henry E. Pluripotent embryonic-like stem cells, compositions, methods and uses thereof
EP1261694B1 (en) 2000-02-26 2008-01-16 Artecel, Inc. Pleuripotent stem cells generated from adipose tissue-derived stromal cells and uses thereof
ATE360063T1 (de) 2000-10-12 2007-05-15 Agency Science Tech & Res Nicht störendes, dreidimensionales system für die kultivierung und ernte verankerungsabhängiger zellen
US20020045260A1 (en) 2000-10-17 2002-04-18 Shih-Chieh Hung Method of isolating mesenchymal stem cells
WO2002040639A2 (en) 2000-11-14 2002-05-23 The University Of Louisville Research Foundation, Inc. Methods for enhancing engraftment of purified hematopoietic stem cells in allogeneic recipients
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
MXPA03005014A (es) 2000-12-06 2004-09-10 Robert J Hariri Metodo para recolectar celulas madres de la placenta.
AU2002251935B2 (en) 2001-02-14 2007-11-29 Celularity Inc. Post-partum mammalian placenta, its use and placental stem cells therefrom
EP2338983B1 (en) 2001-02-14 2015-10-07 Anthrogenesis Corporation Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells
US7504099B2 (en) 2001-12-27 2009-03-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of inducing or enhancing connective tissue repair
US7282222B2 (en) 2002-03-15 2007-10-16 The United States Of America As Represented By The Department Of Veterans Affairs Methods and compositions for directing cells to target organs
AU2003220424A1 (en) 2002-03-19 2003-10-08 Advanced Research And Technology Transfer Adipose stromal stem cells for tissue and vascular modification
US7498171B2 (en) 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
CA2483010A1 (en) 2002-04-19 2003-10-30 University Of Pittsburgh Of The Commonwealth System Of Higher Education Placental derived stem cells and uses thereof
US6875605B1 (en) 2002-08-21 2005-04-05 Florida State University Research Foundation, Inc. Modular cell culture bioreactor and associated methods
US20040258670A1 (en) 2002-12-05 2004-12-23 Case Western Reserve University Cell-based therapies for ischemia
WO2004076642A2 (en) 2003-02-27 2004-09-10 The Rockefeller University Method for modulating epithelial stem cell lineage
ES2569780T3 (es) 2003-06-27 2016-05-12 DePuy Synthes Products, Inc. Células posparto derivadas de tejido placentario y métodos de preparación y uso de las mismas
WO2005113751A1 (en) 2004-05-14 2005-12-01 Becton, Dickinson And Company Cell culture environments for the serum-free expansion of mesenchymal stem cells
DE102004043256B4 (de) 2004-09-07 2013-09-19 Rheinische Friedrich-Wilhelms-Universität Bonn Skalierbarer Prozess zur Kultivierung undifferenzierter Stammzellen in Suspension
WO2006138552A2 (en) 2005-06-15 2006-12-28 Government Of The Usa, As Represented By The Secretary, Dept. Of Health & Human Services Tissue engineered cartilage, method of making same, therapeutic and cosmetic surgical applications using same
KR20180105266A (ko) 2005-12-29 2018-09-27 안트로제네시스 코포레이션 태반 줄기 세포 집단
US20070253931A1 (en) 2006-01-12 2007-11-01 Osiris Therapeutics, Inc. Use of mesenchymal stem cells for treating genetic diseases and disorders
US20080286249A1 (en) * 2006-01-12 2008-11-20 Varney Timothy R Use of mesenchymal stem cells for treating genetic diseases and disorders
US20110171182A1 (en) 2006-03-23 2011-07-14 Pluristem Ltd. Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
US20110293583A1 (en) 2006-03-23 2011-12-01 Pluristem Ltd. Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
KR101490449B1 (ko) 2006-03-23 2015-02-05 플루리스템 리미티드 세포 증식 방법 및 세포의 용도 및 치료를 위해 그 세포에 의해 제조되는 조절된 배지
US20180008649A1 (en) 2006-03-23 2018-01-11 Pluristem Ltd. Adherent stromal cells derived from placentas of multiple donors and uses thereof
WO2011132087A1 (en) * 2010-04-23 2011-10-27 Pluristem Ltd. Adherent stromal cells derived from plancentas of multiple donors and uses thereof
EP1845154A1 (en) * 2006-04-12 2007-10-17 RNL Bio Co., Ltd. Multipotent stem cells derived from placenta tissue and cellular therapeutic agents comprising the same
CN103356710A (zh) 2007-02-12 2013-10-23 人类起源公司 利用胎盘干细胞治疗炎性疾病
ES2392729T5 (es) 2007-09-19 2015-08-28 Pluristem Ltd. Células adherentes de tejidos adiposos o de placenta y uso de las mismas en terapia
US8222206B2 (en) * 2008-03-04 2012-07-17 Taiwan Advance Bio-Pharm Inc. Method of enhancing the mobilization of hematopoietic stem cells using TAT-HOXB4H
EP2303293A1 (en) 2008-05-27 2011-04-06 Pluristem Ltd. Methods of treating inflammatory colon diseases
WO2010033285A2 (en) 2008-06-26 2010-03-25 Spectrum Health Method for treating and preventing radiation damage using genetically modified mesenchymal stem cells
US9096827B2 (en) 2008-09-02 2015-08-04 Pluristem Ltd. Adherent cells from placenta tissue and use thereof in therapy
CA2735790C (en) 2008-09-02 2017-02-28 Pluristem Ltd. Adherent cells from placenta tissue and use thereof in therapy
EP2331957B1 (en) 2008-09-02 2016-11-02 Pluristem Ltd. Methods of selection of cells for transplantation
EP2375907B1 (en) * 2008-11-21 2019-02-27 Celularity, Inc. Treatment of diseases, disorders or conditions of the lung using placental cells
US9175262B2 (en) 2009-11-30 2015-11-03 Pluristerm Ltd. Adherent cells from placenta and use of same in disease treatment
WO2011147967A1 (en) 2010-05-27 2011-12-01 Georg Duda Skeletal muscle regeneration using mesenchymal stem cells
KR101903339B1 (ko) * 2011-03-22 2018-10-01 플루리스템 리미티드 방사선 또는 화학적 손상을 치료하는 방법
KR101910685B1 (ko) 2011-04-15 2018-10-22 플루리스템 리미티드 세포 수집 방법 및 시스템
AU2013311289B2 (en) 2012-09-04 2017-11-16 Pluristem Ltd. Methods for prevention and treatment of preeclampsia
US9512393B2 (en) 2012-09-06 2016-12-06 Pluristem Ltd. Devices and methods for culture of cells
KR102074024B1 (ko) 2012-10-31 2020-02-05 플루리스템 리미티드 생물학적 물질을 해동하기 위한 방법 및 장치

Similar Documents

Publication Publication Date Title
US12545889B2 (en) Colony forming medium and use thereof
JP6654670B2 (ja) 幹細胞の免疫制御作用を調節する方法
Zhou et al. Development and function of myeloid-derived suppressor cells generated from mouse embryonic and hematopoietic stem cells
Kariminekoo et al. Implications of mesenchymal stem cells in regenerative medicine
ES2771248T3 (es) Diferenciación de células NK ex vivo de células hematopoyéticas CD34+
Chen et al. Bone marrow-derived mesenchymal stem cells promote cell proliferation of multiple myeloma through inhibiting T cell immune responses via PD-1/PD-L1 pathway
Aljagthmi et al. Hematopoietic stem cells: Understanding the mechanisms to unleash the therapeutic potential of hematopoietic stem cell transplantation
Huang et al. Sca-1+ cardiac stem cells mediate acute cardioprotection via paracrine factor SDF-1 following myocardial ischemia/reperfusion
Rahimzadeh et al. Biotechnological and biomedical applications of mesenchymal stem cells as a therapeutic system
Pochon et al. Wharton’s jelly‐derived stromal cells and their cell therapy applications in allogeneic haematopoietic stem cell transplantation
KR101968184B1 (ko) 저산소 조건을 이용한 면역세포의 증식 배양 방법
Raheem et al. The emerging role of tissue regulatory T cells in tissue repair and regeneration
Lee et al. The effect of umbilical cord blood derived mesenchymal stem cells in monocrotaline-induced pulmonary artery hypertension rats
JP2015521630A5 (enExample)
Cao et al. Culture and properties of adipose-derived mesenchymal stem cells: characteristics in vitro and immunosuppression in vivo
Wan et al. Cell therapy: A beacon of hope in the battle against pulmonary fibrosis
US20220273716A1 (en) Populations of natural killer cells comprising a cd38 chimeric antigen receptor
JP2014227418A (ja) Ｎｋ細胞の調製方法
Viswanathan et al. Status of stem cell based clinical trials in the treatment for diabetes
WO2020185056A3 (ko) 타가면역세포배양방법, 그 방법으로 얻어진 면역세포배양액 및 이를 포함하는 면역세포치료제
KR102306231B1 (ko) 편도 유래 중간엽 줄기세포로부터 건 세포의 분화방법
WO2014063035A3 (en) Treatment of pain using amnion derived adherent cells
US20250241961A1 (en) Stem cell immunotherapy for colitis
Fløisand et al. PS1223 INTERIM ANALYSIS OF A WT‐1 AND PRAME ‘FAST‐DC’VACCINE SHOWS SAFETY AS ACTIVE IMMMUNOTHERAPY FOR THE PREVENTION OF AML RELAPSE
MX2019007906A (es) Composicion vacunal que comprende un mutante de la interleucina-15 humana.