JP2014505074A - 血圧低下を最小化しおよび／または制御しながら頻脈を治療しおよび／または心拍数を制御する方法 - Google Patents

血圧低下を最小化しおよび／または制御しながら頻脈を治療しおよび／または心拍数を制御する方法 Download PDF

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Publication number
JP2014505074A
JP2014505074A JP2013551327A JP2013551327A JP2014505074A JP 2014505074 A JP2014505074 A JP 2014505074A JP 2013551327 A JP2013551327 A JP 2013551327A JP 2013551327 A JP2013551327 A JP 2013551327A JP 2014505074 A JP2014505074 A JP 2014505074A
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JP
Japan
Prior art keywords
μmol
esmolol
phenylpropionate
propoxy
hydroxy
Prior art date
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Withdrawn
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JP2013551327A
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English (en)
Japanese (ja)
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JP2014505074A5 (enExample
Inventor
バレット ラビナウ，
ジェフ マッキー，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter Healthcare SA
Baxter International Inc
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Baxter Healthcare SA
Baxter International Inc
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Application filed by Baxter Healthcare SA, Baxter International Inc filed Critical Baxter Healthcare SA
Publication of JP2014505074A publication Critical patent/JP2014505074A/ja
Publication of JP2014505074A5 publication Critical patent/JP2014505074A5/ja
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2013551327A 2011-01-27 2012-01-26 血圧低下を最小化しおよび／または制御しながら頻脈を治療しおよび／または心拍数を制御する方法 Withdrawn JP2014505074A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161436992P 2011-01-27 2011-01-27
US61/436,992 2011-01-27
PCT/US2012/022696 WO2012103314A1 (en) 2011-01-27 2012-01-26 Methods of treating tachycardia and/or controlling heart rate while minimizing and/or controlling hypotension

Publications (2)

Publication Number Publication Date
JP2014505074A true JP2014505074A (ja) 2014-02-27
JP2014505074A5 JP2014505074A5 (enExample) 2015-03-19

Family

ID=45567141

Family Applications (1)

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JP2013551327A Withdrawn JP2014505074A (ja) 2011-01-27 2012-01-26 血圧低下を最小化しおよび／または制御しながら頻脈を治療しおよび／または心拍数を制御する方法

Country Status (10)

Country Link
US (2) US8686036B2 (enExample)
EP (1) EP2667867B1 (enExample)
JP (1) JP2014505074A (enExample)
KR (1) KR20140034729A (enExample)
CN (1) CN103338763A (enExample)
AU (1) AU2012211318C1 (enExample)
BR (1) BR112013016701A2 (enExample)
CA (1) CA2825311A1 (enExample)
MX (1) MX2013008713A (enExample)
WO (1) WO2012103314A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012211309B2 (en) 2011-01-27 2014-10-09 Baxter Healthcare Sa Use of (S) - esmolol for controlling venous irritation associated with the treatment of a cardiac disorder
RU2613564C1 (ru) * 2015-12-02 2017-03-17 федеральное государственное бюджетное образовательное учреждение высшего образования "Северо-Западный государственный медицинский университет имени И.И. Мечникова" Министерства здравоохранения Российской Федерации (ФГБОУ ВО СЗГМУ им. И.И. Мечникова Минздрава России) Способ прогнозирования интраоперационной артериальной гипотензии при проведении анестезии

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0720861B2 (ja) 1984-04-09 1995-03-08 ザ デュポン マーク ファーマソウテイカル カンパニー 心臓障害の処置または予防用の医薬組成物および方法
JPS63502585A (ja) * 1985-12-04 1988-09-29 ザ　デュポン　メルク　ファーマシュウティカル　カンパニー アリルオキシプロパノ−ルアミン類及びアリルエタノ−ルアミン類の合成法
WO1988001614A1 (en) 1986-09-02 1988-03-10 E.I. Du Pont De Nemours And Company RESOLUTION OF dl-METHYL 3-[4-(2-HYDROXY-3-ISOPROPYLAMINO)PROPOXY]PHENYLPROPIONATE [(dl-ESMOLOL)]
US4857552A (en) 1988-06-08 1989-08-15 E. I. Du Pont De Nemours And Co. Stable pharmaceutical composition
US5849843A (en) 1993-11-16 1998-12-15 Baxter International Inc. Polymeric compositions for medical packaging and devices
US5998019A (en) 1993-11-16 1999-12-07 Baxter International Inc. Multi-layered polymer structure for medical products
US5977409A (en) 1997-04-15 1999-11-02 University Of Toledo Method of using α-substituted benzylamine chiral auxiliary synthetic reagents
US6310094B1 (en) 2001-01-12 2001-10-30 Baxter International Inc. Ready-to-use esmolol solution
TWI277414B (en) 2001-01-12 2007-04-01 Baxter Int Esmolol formulation
ATE533509T1 (de) * 2003-08-08 2011-12-15 Ono Pharmaceutical Co Herzverlangsamender arzneistoff mit beta-blockern mit kurzzeitwirkung als wirkstoff
US20080293814A1 (en) 2007-05-22 2008-11-27 Deepak Tiwari Concentrate esmolol
CN101323580A (zh) 2008-07-25 2008-12-17 河北科技大学 手性芳氧丙醇胺类化合物及其盐的合成方法
CN101881755B (zh) 2009-05-04 2013-05-29 南京海辰药业有限公司 通过高效液相色谱法检测盐酸艾司洛尔光学异构体的方法
CN101891636A (zh) 2009-05-21 2010-11-24 南京海辰药业有限公司 制备盐酸艾司洛尔光学异构体的新方法
CN102106846A (zh) 2009-12-23 2011-06-29 南京海辰药业有限公司 左旋盐酸艾司洛尔药物组合物及其制备方法
AU2012211309B2 (en) 2011-01-27 2014-10-09 Baxter Healthcare Sa Use of (S) - esmolol for controlling venous irritation associated with the treatment of a cardiac disorder

Also Published As

Publication number Publication date
CA2825311A1 (en) 2012-08-02
CN103338763A (zh) 2013-10-02
BR112013016701A2 (pt) 2017-07-04
AU2012211318A1 (en) 2013-05-02
US9084763B2 (en) 2015-07-21
US8686036B2 (en) 2014-04-01
EP2667867B1 (en) 2015-05-27
US20140066503A1 (en) 2014-03-06
AU2012211318B2 (en) 2016-01-28
EP2667867A1 (en) 2013-12-04
WO2012103314A1 (en) 2012-08-02
KR20140034729A (ko) 2014-03-20
MX2013008713A (es) 2013-08-29
US20120302637A1 (en) 2012-11-29
AU2012211318C1 (en) 2016-08-04

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