JP2014504865A5 - - Google Patents

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Publication number
JP2014504865A5
JP2014504865A5 JP2013547842A JP2013547842A JP2014504865A5 JP 2014504865 A5 JP2014504865 A5 JP 2014504865A5 JP 2013547842 A JP2013547842 A JP 2013547842A JP 2013547842 A JP2013547842 A JP 2013547842A JP 2014504865 A5 JP2014504865 A5 JP 2014504865A5
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JP
Japan
Prior art keywords
nucleic acid
acid molecule
reference nucleic
binding
level
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2013547842A
Other languages
English (en)
Japanese (ja)
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JP2014504865A (ja
Filing date
Publication date
Priority claimed from PCT/EP2011/002068 external-priority patent/WO2011131371A1/en
Application filed filed Critical
Priority claimed from PCT/EP2012/000089 external-priority patent/WO2012095303A1/en
Publication of JP2014504865A publication Critical patent/JP2014504865A/ja
Publication of JP2014504865A5 publication Critical patent/JP2014504865A5/ja
Pending legal-status Critical Current

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JP2013547842A 2011-01-10 2012-01-10 標的分子との結合親和性を有する核酸分子およびその生成方法 Pending JP2014504865A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP11000117.9 2011-01-10
EP11000117 2011-01-10
PCT/EP2011/002068 WO2011131371A1 (en) 2010-04-21 2011-04-21 Lipid binding nucleic acids
EPPCT/EP2011/002068 2011-04-21
EP11008467 2011-10-21
EP11008467.0 2011-10-21
PCT/EP2012/000089 WO2012095303A1 (en) 2011-01-10 2012-01-10 Nucleic acid molecule having binding affinity to a target molecule and a method for generating the same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017075557A Division JP2017148055A (ja) 2011-01-10 2017-04-05 標的分子との結合親和性を有する核酸分子およびその生成方法

Publications (2)

Publication Number Publication Date
JP2014504865A JP2014504865A (ja) 2014-02-27
JP2014504865A5 true JP2014504865A5 (https=) 2015-03-05

Family

ID=45464586

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013547842A Pending JP2014504865A (ja) 2011-01-10 2012-01-10 標的分子との結合親和性を有する核酸分子およびその生成方法
JP2017075557A Pending JP2017148055A (ja) 2011-01-10 2017-04-05 標的分子との結合親和性を有する核酸分子およびその生成方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2017075557A Pending JP2017148055A (ja) 2011-01-10 2017-04-05 標的分子との結合親和性を有する核酸分子およびその生成方法

Country Status (8)

Country Link
US (2) US9976145B2 (https=)
EP (1) EP2663640B1 (https=)
JP (2) JP2014504865A (https=)
KR (2) KR102080142B1 (https=)
CN (1) CN103339258A (https=)
AU (1) AU2012206750A1 (https=)
CA (1) CA2824073A1 (https=)
WO (1) WO2012095303A1 (https=)

Families Citing this family (10)

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Publication number Priority date Publication date Assignee Title
JP2014533098A (ja) * 2011-10-21 2014-12-11 ノクソン・ファルマ・アクチエンゲゼルシャフト グルカゴン結合核酸
KR102034203B1 (ko) * 2012-01-10 2019-10-18 아프타리온 바이오테크 아게 새로운 C5a 결합 핵산
BR112014016939A2 (pt) * 2012-01-10 2019-09-24 Noxxon Pharma Ag ácidos nucleicos que se ligam especificamente a cgrp
US11172873B2 (en) 2018-05-17 2021-11-16 The Procter & Gamble Company Systems and methods for hair analysis
WO2019222340A1 (en) 2018-05-17 2019-11-21 The Procter & Gamble Company Systems and methods for hair coverage analysis
CN112771164B (zh) 2018-06-29 2026-03-27 宝洁公司 用于个人护理应用的适配体
CA3134968A1 (en) 2019-04-16 2020-10-22 Juan Esteban Velasquez Aptamers for odor control applications
US12039732B2 (en) 2021-04-14 2024-07-16 The Procter & Gamble Company Digital imaging and learning systems and methods for analyzing pixel data of a scalp region of a users scalp to generate one or more user-specific scalp classifications
EP4306640A1 (en) 2022-06-21 2024-01-17 TME Pharma AG Method for treating a tumor in a subject
KR20250025627A (ko) 2022-06-21 2025-02-24 티엠이 파마 아게 대상체의 종양을 치료하는 방법

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2259800T3 (es) 1990-06-11 2006-10-16 Gilead Sciences, Inc. Procedimientos de uso de ligandos de acido nucleico.
US6011020A (en) 1990-06-11 2000-01-04 Nexstar Pharmaceuticals, Inc. Nucleic acid ligand complexes
DE59708838D1 (de) 1996-08-30 2003-01-09 Jens Peter Fuerste Spiegelselektion und spiegelevolution von nucleinsäuren
US6395029B1 (en) 1999-01-19 2002-05-28 The Children's Hospital Of Philadelphia Sustained delivery of polyionic bioactive agents
US6652886B2 (en) 2001-02-16 2003-11-25 Expression Genetics Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents
EP1264603B8 (en) * 2001-06-10 2010-03-03 Noxxon Pharma AG Use of L-polynucleotides for in vivo imaging
EP1306382A1 (de) 2001-10-26 2003-05-02 Noxxon Pharma AG Modifizierte L-Nukleinsäure
ATE469164T1 (de) 2001-10-26 2010-06-15 Noxxon Pharma Ag Modifizierte l-nukleinsäure
WO2003070823A2 (en) 2002-02-20 2003-08-28 The General Hospital Corporation Conjugates comprising a biodegradable polymer and uses therefor
NZ542687A (en) 2003-04-13 2010-02-26 Enzon Pharmaceuticals Inc Polymeric oligonucleotide prodrugs
GB0314472D0 (en) 2003-06-20 2003-07-23 Warwick Effect Polymers Ltd Polymer
OA13282A (en) 2003-11-10 2007-01-31 Noxxon Pharma Ag Nucleic acids specifically binding bioactive ghrelin.
CA2555467C (en) 2004-02-09 2012-10-09 Noxxon Pharma Ag Process for the production of conjugates from polysaccharides and polynucleotides
CA2940803A1 (en) 2004-03-23 2005-10-27 Ascendis Pharma Gmbh Prodrug linker
US7579450B2 (en) 2004-04-26 2009-08-25 Archemix Corp. Nucleic acid ligands specific to immunoglobulin E and their use as atopic disease therapeutics
JP5107716B2 (ja) 2004-11-05 2012-12-26 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア 分子治療用生分解性リンカー
US20090075342A1 (en) 2005-04-26 2009-03-19 Sharon Cload Metabolic profile directed aptamer medicinal chemistry
US20120101267A1 (en) 2005-10-07 2012-04-26 Alison Velyian Todd Multicomponent nucleic acid enzymes with cleavage, ligase or other activity and methods for their use
JP5665272B2 (ja) 2005-10-07 2015-02-04 スピーデクス ピーティーワイ リミテッド 多成分核酸酵素およびそれらの使用方法
MX2009002859A (es) 2006-09-15 2009-03-30 Enzon Pharmaceuticals Inc Enlazadores biodegradables a base de ester impedido para suministro de oligonucleotidos.
US8962238B2 (en) 2007-04-05 2015-02-24 SpeedDx Pty Ltd Nucleic acid enzymes and complexes and methods for their use
WO2010014572A2 (en) * 2008-07-28 2010-02-04 Idera Pharmaceuticals, Inc. Modulation of toll-like receptor 9 expression by antisense oligonucleotides
EP2561079A1 (en) 2010-04-21 2013-02-27 Noxxon Pharma AG Lipid binding nucleic acids

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