JP2014504500A5 - - Google Patents

Download PDF

Info

Publication number
JP2014504500A5
JP2014504500A5 JP2013546722A JP2013546722A JP2014504500A5 JP 2014504500 A5 JP2014504500 A5 JP 2014504500A5 JP 2013546722 A JP2013546722 A JP 2013546722A JP 2013546722 A JP2013546722 A JP 2013546722A JP 2014504500 A5 JP2014504500 A5 JP 2014504500A5
Authority
JP
Japan
Prior art keywords
expression system
virus
protein
polynucleotide
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013546722A
Other languages
English (en)
Japanese (ja)
Other versions
JP6324725B2 (ja
JP2014504500A (ja
Filing date
Publication date
Priority claimed from PCT/EP2010/007995 external-priority patent/WO2012089231A1/en
Application filed filed Critical
Publication of JP2014504500A publication Critical patent/JP2014504500A/ja
Publication of JP2014504500A5 publication Critical patent/JP2014504500A5/ja
Application granted granted Critical
Publication of JP6324725B2 publication Critical patent/JP6324725B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2013546722A 2010-12-30 2011-12-30 発現系 Expired - Fee Related JP6324725B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/EP2010/007995 WO2012089231A1 (en) 2010-12-30 2010-12-30 Paramyxovirus vaccines
EPPCT/EP2010/007995 2010-12-30
PCT/EP2011/074307 WO2012089833A2 (en) 2010-12-30 2011-12-30 Expression Systems

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017004556A Division JP2017079787A (ja) 2010-12-30 2017-01-13 発現系

Publications (3)

Publication Number Publication Date
JP2014504500A JP2014504500A (ja) 2014-02-24
JP2014504500A5 true JP2014504500A5 (https=) 2015-02-19
JP6324725B2 JP6324725B2 (ja) 2018-05-16

Family

ID=45464575

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013546722A Expired - Fee Related JP6324725B2 (ja) 2010-12-30 2011-12-30 発現系
JP2017004556A Pending JP2017079787A (ja) 2010-12-30 2017-01-13 発現系

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2017004556A Pending JP2017079787A (ja) 2010-12-30 2017-01-13 発現系

Country Status (23)

Country Link
US (4) US20140141042A1 (https=)
EP (2) EP2658573B1 (https=)
JP (2) JP6324725B2 (https=)
KR (1) KR102070463B1 (https=)
CN (1) CN103442731B (https=)
AU (2) AU2011351380A1 (https=)
BR (1) BR112013016823A2 (https=)
CA (1) CA2821111A1 (https=)
CY (1) CY1124146T1 (https=)
DK (1) DK2658573T3 (https=)
ES (1) ES2869199T3 (https=)
HR (1) HRP20210750T1 (https=)
HU (1) HUE053986T2 (https=)
IL (1) IL226551B (https=)
LT (1) LT2658573T (https=)
MX (1) MX352205B (https=)
NZ (1) NZ610743A (https=)
PL (1) PL2658573T3 (https=)
PT (1) PT2658573T (https=)
RU (1) RU2609645C2 (https=)
SG (2) SG10201510760WA (https=)
SI (1) SI2658573T1 (https=)
WO (2) WO2012089231A1 (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3842068A1 (en) 2012-07-05 2021-06-30 GlaxoSmithKline Biologicals S.A. Novel prime-boosting regimens involving immunogenic polypeptides encoded by polynucleotides
DK2879702T3 (da) * 2012-08-01 2020-02-24 Bavarian Nordic As Rekombinant modificeret vacciniavirus ankara (mva)-vaccine mod respiratorisk syncytialvirus (rsv)
KR102435054B1 (ko) * 2012-08-01 2022-08-22 버베리안 노딕 에이/에스 재조합 변형된 백시니아 바이러스 앙카라(ankara) (mva) 호흡기 신시티알 바이러스(rsv) 백신
US20140037680A1 (en) 2012-08-06 2014-02-06 Glaxosmithkline Biologicals, S.A. Novel method
AU2013301312A1 (en) 2012-08-06 2015-03-19 Glaxosmithkline Biologicals S.A. Method for eliciting in infants an immune response against RSV and B. pertussis
CA2900110A1 (en) * 2013-02-01 2014-08-07 Medimmune, Llc Respiratory syncytial virus f protein epitopes
US20140286981A1 (en) 2013-03-14 2014-09-25 Wisconsin Alumni Research Foundation Broadly reactive mosaic peptide for influenza vaccine
EP3653701A1 (en) 2013-03-15 2020-05-20 The Research Foundation for The State University of New York Attenuated influenza viruses and vaccines
MX2016001695A (es) 2013-08-05 2016-05-02 Glaxosmithkline Biolog Sa Composiciones inmunogenas de combinacion.
MX384992B (es) 2014-06-13 2025-03-14 Glaxosmithkline Biologicals Sa Combinaciones inmunógenas.
BR112017026523A2 (pt) 2015-06-12 2018-08-14 Glaxosmithkline Biologicals Sa vetor recombinante, adenovírus recombinante, composição, uso de um vetor recombinante, de um adenovírus recombinante ou de uma composição, método para induzir uma resposta imune em um indivíduo, e, polinucleotídeo isolado.
EP4011451A1 (en) * 2015-10-22 2022-06-15 ModernaTX, Inc. Metapneumovirus mrna vaccines
GB201614485D0 (en) 2016-08-25 2016-10-12 Univ Oxford Innovation Ltd Immunogenic composition
WO2018060288A1 (en) 2016-09-29 2018-04-05 Glaxosmithkline Biologicals S.A. Compositions and methods of treatment of persistent hpv infection
WO2018107088A2 (en) 2016-12-08 2018-06-14 Modernatx, Inc. Respiratory virus nucleic acid vaccines
ES2959811T3 (es) 2016-12-09 2024-02-28 Glaxosmithkline Biologicals Sa Construcciones de adenovirus de chimpancé con antígenos de Lyssavirus
GB201620968D0 (en) 2016-12-09 2017-01-25 Glaxosmithkline Biologicals Sa Adenovirus polynucleotides and polypeptides
GB201701239D0 (en) 2017-01-25 2017-03-08 Glaxosmithkline Biologicals Sa Novel formulation
CN107119064A (zh) * 2017-02-21 2017-09-01 南京农业大学 重组枯草芽孢杆菌串联表达禽流感病毒ha抗原片段和pb1-f2蛋白
EP3697902A1 (en) 2017-10-16 2020-08-26 GlaxoSmithKline Biologicals S.A. Enhanced promoter
EP3697919A1 (en) 2017-10-16 2020-08-26 GlaxoSmithKline Biologicals SA Adenoviral vectors with two expression cassettes encoding rsv antigenic proteins or fragments thereof
JP2021500880A (ja) 2017-10-16 2021-01-14 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 2つの発現カセットを有するサルアデノウイルスベクター
AU2018356538B2 (en) * 2017-10-25 2023-09-28 Nouscom Ag Eukaryotic cell line
BR112020012361A2 (pt) 2017-12-20 2020-11-24 Glaxosmithkline Biologicals S.A. constructos de antígeno do vírus epstein-barr
EP3807298A1 (en) 2018-06-12 2021-04-21 GlaxoSmithKline Biologicals S.A. Adenovirus polynucleotides and polypeptides
WO2020014656A1 (en) * 2018-07-13 2020-01-16 University Of Georgia Research Foundation Broadly reactive immunogens of influenza h3 virus, compositions and methods of use thereof
CN109180820B (zh) * 2018-09-19 2021-06-25 天康生物制药有限公司 马流感病毒h3n8亚型的融合蛋白及其制备方法、应用和疫苗
WO2020061443A2 (en) * 2018-09-21 2020-03-26 Board Of Regents Of The University Of Nebraska Methods of making and using universal centralized influenza vaccine genes
US11351242B1 (en) 2019-02-12 2022-06-07 Modernatx, Inc. HMPV/hPIV3 mRNA vaccine composition
CN112220921B (zh) * 2020-08-25 2022-08-16 北京交通大学 一种针对呼吸道合胞病毒感染的组合疫苗

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7135312B2 (en) * 1993-04-15 2006-11-14 University Of Rochester Circular DNA vectors for synthesis of RNA and DNA
DE19651443A1 (de) * 1996-12-11 1998-06-18 Hoechst Ag Selbstverstärkende, pharmakologisch kontrollierbare Expressionssysteme
US7655774B2 (en) 2000-02-18 2010-02-02 University Of Washington Ancestral and COT viral sequences, proteins and immunogenic compositions
US20040096451A1 (en) * 2002-07-25 2004-05-20 Young James F. Methods of treating and preventing RSV, hMPV, and PIV using anti-RSV, anti-hMPV, and anti-PIV antibodies
EP1441762A1 (en) * 2001-09-28 2004-08-04 University Of South Florida Rsv gene expression vaccine
AU2002365366B2 (en) * 2001-11-21 2007-05-10 The Trustees Of The University Of Pennsylvania Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use
EP1485468A4 (en) * 2002-02-21 2007-01-03 Medimmune Vaccines Inc RECOMBINANT PARAIN FLUENZAVIRUS EXPRESSION SYSTEMS AND VACCINES WITH ANTIGENS FROM METAPNEUMOVIRUS STEM-RELATED HETEROLOGISTS
US20050136035A1 (en) * 2003-06-03 2005-06-23 Derek Ko Cell specific replication-competent viral vectors comprising a self processing peptide cleavage site
US7566458B2 (en) * 2003-06-16 2009-07-28 Medimmune, Llc Influenza hemagglutinin and neuraminidase variants
DE602005017743D1 (de) 2004-01-23 2009-12-31 Angeletti P Ist Richerche Bio Impfstoffträger für schimpansen-adenovirus
WO2007126887A2 (en) * 2006-03-27 2007-11-08 The Government Of The United States Of America Immunogenic compositions comprising polynucleotides encoding matrix protein 2 and methods of use
WO2008054540A2 (en) * 2006-05-18 2008-05-08 Pharmexa Inc. Inducing immune responses to influenza virus using polypeptide and nucleic acid compositions
AU2007345319B2 (en) * 2006-07-13 2012-09-06 Institute For Advanced Study Viral inhibitory nucleotide sequences and vaccines
DE202007018643U1 (de) 2006-09-05 2009-01-02 BSH Bosch und Siemens Hausgeräte GmbH Bodendüse für Hartböden
WO2008133663A2 (en) * 2006-11-30 2008-11-06 Government Of The United States Of America, As Represented By The Secretary, Codon modified immunogenic compositions and methods of use
WO2009092113A2 (en) * 2008-01-19 2009-07-23 Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods and compositions for the delivery of vaccines to disrupted epithelium
US20100040650A1 (en) * 2008-05-30 2010-02-18 Crowe Jr James E Virus-Like paramyxovirus particles and vaccines
WO2009146902A1 (en) * 2008-06-03 2009-12-10 Okairòs Ag A vaccine for the prevention and therapy of hcv infections
JP5781929B2 (ja) * 2008-07-15 2015-09-24 ノバルティス アーゲー 免疫原性の両親媒性ペプチド組成物
WO2010077712A1 (en) * 2008-12-09 2010-07-08 Novavax, Inc. Bovine respiratory syncytial virus virus-like particle (vlps)
PL2370099T3 (pl) * 2008-12-09 2016-10-31 Zmodyfikowane białka F RSV i sposoby ich zastosowania
JP2010168288A (ja) * 2009-01-20 2010-08-05 Yokohama City Univ 最適化した抗原遺伝子の使用によるウイルスワクチンの免疫原性の増強
PL2391638T3 (pl) 2009-02-02 2018-11-30 Glaxosmithkline Biologicals Sa Sekwencje nukleotydowe i aminokwasowe małpiego adenowirusa, zawierające je wektory i ich zastosowania

Similar Documents

Publication Publication Date Title
JP2014504500A5 (https=)
RU2013135498A (ru) Экспрессионные системы
Cheung et al. Biology of influenza a virus
US12364746B2 (en) Mosaic influenza virus hemagglutinin polypeptides and uses thereof
Bouvier et al. The biology of influenza viruses
CA2805505C (en) Chimeric influenza viruses having reduced ability to reassort with other influenza viruses and uses thereof
JP2015506689A5 (https=)
CA2848117A1 (en) Recombinant influenza virus highly expressing ha protein and preparation method and use thereof
AR076690A1 (es) Vacuna universal contra la influenza basada en un virus vaccinia ankara modificado (mva) recombinante
IL321503A (en) Recombinant virus, composition comprising the same, and uses thereof
Urbaniak et al. In vivo reassortment of influenza viruses
JP2019500860A5 (https=)
JP6335167B2 (ja) 感染性インフルエンザウイルスの産生
RU2013150802A (ru) Способы выделения и определения количественного содержания антигена в вакцинах
Wang et al. PA from an H5N1 highly pathogenic avian influenza virus activates viral transcription and replication and induces apoptosis and interferon expression at an early stage of infection
Timofeeva et al. Mutations in the genome of avian influenza viruses of the H1 and H5 subtypes responsible for adaptation to mammals
Abbas et al. Proteins of Influenza Virus: A Review
JP2017531032A (ja) ワクチン抗原の製造方法、得られるワクチン抗原、および使用
Kwon et al. Characterization of a chicken embryo-adapted H9N2 subtype avian influenza virus
Wong et al. Steps toward a universal influenza vaccine: research models and comparison of current approaches
Tsuda et al. Factors responsible for plaque formation of A/duck/Siberia/272/1998 (H13N6) influenza virus on MDCK cells
Hartgroves et al. Rapid generation of a well-matched vaccine seed from a modern influenza A virus primary isolate without recourse to eggs
Lee et al. Control technique of avian influenza
Lee et al. Complete genome sequence of a natural recombinant H9N2 influenza virus from wild birds in Republic of Korea
Wang et al. Complete genome sequences of six avian-like H1N1 swine influenza viruses from northwestern China