JP2014503222A5 - - Google Patents
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- Publication number
- JP2014503222A5 JP2014503222A5 JP2013549609A JP2013549609A JP2014503222A5 JP 2014503222 A5 JP2014503222 A5 JP 2014503222A5 JP 2013549609 A JP2013549609 A JP 2013549609A JP 2013549609 A JP2013549609 A JP 2013549609A JP 2014503222 A5 JP2014503222 A5 JP 2014503222A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- recurrence
- patient
- colorectal cancer
- expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010009944 Colon cancer Diseases 0.000 claims description 48
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims description 48
- 230000014509 gene expression Effects 0.000 claims description 47
- 238000003556 assay Methods 0.000 claims description 32
- 150000007523 nucleic acids Chemical group 0.000 claims description 32
- 238000004458 analytical method Methods 0.000 claims description 19
- 238000000034 method Methods 0.000 claims description 15
- 239000000523 sample Substances 0.000 claims description 15
- 239000013610 patient sample Substances 0.000 claims description 13
- 230000002068 genetic effect Effects 0.000 claims description 7
- 108091026890 Coding region Proteins 0.000 claims description 6
- 108091092584 GDNA Proteins 0.000 claims description 6
- 108700019961 Neoplasm Genes Proteins 0.000 claims description 6
- 102000048850 Neoplasm Genes Human genes 0.000 claims description 6
- 230000003321 amplification Effects 0.000 claims description 6
- 230000000295 complement effect Effects 0.000 claims description 6
- 239000002299 complementary DNA Substances 0.000 claims description 6
- 238000009396 hybridization Methods 0.000 claims description 6
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 6
- 108091033319 polynucleotide Proteins 0.000 claims description 6
- 102000040430 polynucleotide Human genes 0.000 claims description 6
- 239000002157 polynucleotide Substances 0.000 claims description 6
- 108090000623 proteins and genes Proteins 0.000 claims description 6
- 239000011159 matrix material Substances 0.000 claims description 4
- 238000002493 microarray Methods 0.000 claims description 2
- 108020004707 nucleic acids Proteins 0.000 claims description 2
- 102000039446 nucleic acids Human genes 0.000 claims description 2
- 238000004445 quantitative analysis Methods 0.000 claims description 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 238000004393 prognosis Methods 0.000 claims 1
- 238000010276 construction Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161433798P | 2011-01-18 | 2011-01-18 | |
| US61/433,798 | 2011-01-18 | ||
| PCT/US2012/021539 WO2012099872A1 (en) | 2011-01-18 | 2012-01-17 | Prognostic signature for colorectal cancer recurrence |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014503222A JP2014503222A (ja) | 2014-02-13 |
| JP2014503222A5 true JP2014503222A5 (enExample) | 2015-01-22 |
Family
ID=46516038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013549609A Pending JP2014503222A (ja) | 2011-01-18 | 2012-01-17 | 結腸直腸がん再発に関する予後のサイン |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9234245B2 (enExample) |
| EP (1) | EP2665835B1 (enExample) |
| JP (1) | JP2014503222A (enExample) |
| KR (1) | KR20140040694A (enExample) |
| CN (1) | CN103403187A (enExample) |
| AU (1) | AU2012207442B2 (enExample) |
| CA (1) | CA2825046A1 (enExample) |
| IL (1) | IL227419A (enExample) |
| MX (1) | MX2013008252A (enExample) |
| WO (1) | WO2012099872A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6757560B2 (ja) * | 2014-09-26 | 2020-09-23 | シスメックス株式会社 | 大腸癌の再発リスク診断を補助する方法、プログラムおよびコンピュータシステム |
| US10900084B2 (en) | 2015-09-16 | 2021-01-26 | Sysmex Corporation | Method for supporting diagnosis of risk of colorectal cancer recurrence, treatment of colorectal cancer, and administration of anticancer drug |
| SE540173C2 (en) * | 2016-04-20 | 2018-04-24 | Hiloprobe Ab | Marker genes for colorectal cancer classification, method for judging lymph node metastasis for prognosis of colorectal cancer and kit therefor |
| EP3743534B1 (en) | 2018-01-22 | 2022-03-23 | Liquid Biopsy Research LLC | Methods for colon cancer detection and treatment monitoring |
| IL311084A (en) * | 2018-11-30 | 2024-04-01 | Caris Mpi Inc | New generation molecular characterization |
| CN111321221B (zh) * | 2018-12-14 | 2022-09-23 | 中国医学科学院肿瘤医院 | 用于预测直肠癌局部切除手术后复发风险的组合物、微阵列和计算机系统 |
| CN109929934B (zh) * | 2019-03-27 | 2022-09-09 | 中山大学附属第六医院 | 免疫相关基因在结直肠癌预后的试剂盒和系统中的应用 |
| CN113436741B (zh) * | 2021-07-16 | 2023-02-28 | 四川大学华西医院 | 基于组织特异增强子区域dna甲基化的肺癌复发预测方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6582908B2 (en) * | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
| GB9425138D0 (en) * | 1994-12-12 | 1995-02-08 | Dynal As | Isolation of nucleic acid |
| US20020068277A1 (en) * | 1998-11-20 | 2002-06-06 | Simpson Andrew John George | Method for determining nucleotide sequences using arbitrary primers and low stringency |
| AU2003222221A1 (en) * | 2002-02-15 | 2004-10-25 | The General Hospital Corporation | Map-kinase inhibitors as regulators of tumour-associated antigen expression |
| GB0323226D0 (en) * | 2003-10-03 | 2003-11-05 | Ncc Technology Ventures Pte Lt | Materials and methods relating to breast cancer diagnosis |
| WO2005085861A2 (en) | 2004-03-03 | 2005-09-15 | Oridis Biomed Forschungs- Und Entwicklungs Gmbh | Nucleic acids and encoded polypeptides for use in liver disorders and epithelial cancer |
| AU2005321898B2 (en) * | 2004-12-29 | 2012-07-19 | Mannkind Corporation | Use of compositions comprising various tumor-associated antigens as anti-cancer vaccines |
| US20060257902A1 (en) | 2005-03-25 | 2006-11-16 | Ambion, Inc. | Methods and compositions for depleting abundant RNA transcripts |
| JP5244103B2 (ja) * | 2006-08-09 | 2013-07-24 | ホームステッド クリニカル コーポレイション | 器官特異的蛋白質およびその使用方法 |
| EP2080140B1 (en) * | 2006-11-03 | 2013-04-24 | Baylor Research Institute | Diagnosis of metastatic melanoma and monitoring indicators of immunosuppression through blood leukocyte microarray analysis |
| AT504702A1 (de) * | 2006-12-22 | 2008-07-15 | Arc Austrian Res Centers Gmbh | Set von tumormarkern |
| JP2010178650A (ja) * | 2009-02-04 | 2010-08-19 | Univ Of Tokyo | 固形癌の再発予測のための試験方法および再発予防剤 |
| GB0904904D0 (en) * | 2009-03-23 | 2009-05-06 | Univ Leiden Medical Ct | Angiogenesis methods, medicaments and agents |
-
2012
- 2012-01-17 MX MX2013008252A patent/MX2013008252A/es not_active Application Discontinuation
- 2012-01-17 CA CA2825046A patent/CA2825046A1/en not_active Abandoned
- 2012-01-17 WO PCT/US2012/021539 patent/WO2012099872A1/en not_active Ceased
- 2012-01-17 KR KR1020137020961A patent/KR20140040694A/ko not_active Withdrawn
- 2012-01-17 JP JP2013549609A patent/JP2014503222A/ja active Pending
- 2012-01-17 US US13/351,485 patent/US9234245B2/en not_active Expired - Fee Related
- 2012-01-17 CN CN2012800105712A patent/CN103403187A/zh active Pending
- 2012-01-17 AU AU2012207442A patent/AU2012207442B2/en not_active Ceased
- 2012-01-17 EP EP12736444.6A patent/EP2665835B1/en not_active Not-in-force
-
2013
- 2013-07-10 IL IL227419A patent/IL227419A/en active IP Right Grant
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