JP2014502160A5 - - Google Patents
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- Publication number
- JP2014502160A5 JP2014502160A5 JP2013541927A JP2013541927A JP2014502160A5 JP 2014502160 A5 JP2014502160 A5 JP 2014502160A5 JP 2013541927 A JP2013541927 A JP 2013541927A JP 2013541927 A JP2013541927 A JP 2013541927A JP 2014502160 A5 JP2014502160 A5 JP 2014502160A5
- Authority
- JP
- Japan
- Prior art keywords
- arthritis
- disease
- dermatitis
- chronic
- acute
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 206010003246 Arthritis Diseases 0.000 description 8
- 206010039073 Rheumatoid arthritis Diseases 0.000 description 4
- 206010006451 Bronchitis Diseases 0.000 description 3
- 200000000018 inflammatory disease Diseases 0.000 description 3
- 206010011732 Cyst Diseases 0.000 description 2
- 206010021972 Inflammatory bowel disease Diseases 0.000 description 2
- 208000002193 Pain Diseases 0.000 description 2
- 230000001154 acute Effects 0.000 description 2
- 230000035939 shock Effects 0.000 description 2
- 201000002661 spondylitis Diseases 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 206010001053 Acute respiratory failure Diseases 0.000 description 1
- 206010003230 Arteritis Diseases 0.000 description 1
- 206010003256 Arthritis gonococcal Diseases 0.000 description 1
- 206010003267 Arthritis reactive Diseases 0.000 description 1
- 206010003274 Arthritis viral Diseases 0.000 description 1
- 208000006673 Asthma Diseases 0.000 description 1
- 208000009137 Behcet Syndrome Diseases 0.000 description 1
- 201000008335 Behcet's disease Diseases 0.000 description 1
- 206010006448 Bronchiolitis Diseases 0.000 description 1
- 206010006458 Bronchitis chronic Diseases 0.000 description 1
- 206010007882 Cellulitis Diseases 0.000 description 1
- 208000007451 Chronic Bronchitis Diseases 0.000 description 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 description 1
- 208000010247 Contact Dermatitis Diseases 0.000 description 1
- 206010012438 Dermatitis atopic Diseases 0.000 description 1
- 206010012442 Dermatitis contact Diseases 0.000 description 1
- 206010012455 Dermatitis exfoliative Diseases 0.000 description 1
- 208000005679 Eczema Diseases 0.000 description 1
- 208000004526 Exfoliative Dermatitis Diseases 0.000 description 1
- 206010016207 Familial mediterranean fever Diseases 0.000 description 1
- 206010016629 Fibroma Diseases 0.000 description 1
- 208000007465 Giant Cell Arteritis Diseases 0.000 description 1
- 206010072579 Granulomatosis with polyangiitis Diseases 0.000 description 1
- 206010018872 Haemochromatosis Diseases 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 206010020118 Histiocytosis Diseases 0.000 description 1
- 208000004575 Infectious Arthritis Diseases 0.000 description 1
- 206010022114 Injury Diseases 0.000 description 1
- 206010024377 Leukocytoclastic vasculitis Diseases 0.000 description 1
- 206010025135 Lupus erythematosus Diseases 0.000 description 1
- 206010025169 Lyme disease Diseases 0.000 description 1
- 208000000112 Myalgia Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010031252 Osteomyelitis Diseases 0.000 description 1
- 206010033645 Pancreatitis Diseases 0.000 description 1
- 206010034674 Peritonitis Diseases 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 206010037162 Psoriatic arthropathy Diseases 0.000 description 1
- 206010037549 Purpura Diseases 0.000 description 1
- 241001672981 Purpura Species 0.000 description 1
- 208000002574 Reactive Arthritis Diseases 0.000 description 1
- 206010038294 Reiter's syndrome Diseases 0.000 description 1
- 206010039085 Rhinitis allergic Diseases 0.000 description 1
- 206010041303 Solar dermatitis Diseases 0.000 description 1
- 206010043207 Temporal arteritis Diseases 0.000 description 1
- 208000002240 Tennis Elbow Diseases 0.000 description 1
- 206010047115 Vasculitis Diseases 0.000 description 1
- 208000004762 Vasculitis, Leukocytoclastic, Cutaneous Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 201000010105 allergic rhinitis Diseases 0.000 description 1
- 201000004384 alopecia Diseases 0.000 description 1
- 201000008937 atopic dermatitis Diseases 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 230000001684 chronic Effects 0.000 description 1
- 201000004624 dermatitis Diseases 0.000 description 1
- 231100000406 dermatitis Toxicity 0.000 description 1
- 231100000080 dermatitis contact Toxicity 0.000 description 1
- 201000011275 epicondylitis Diseases 0.000 description 1
- 230000002538 fungal Effects 0.000 description 1
- 201000005569 gout Diseases 0.000 description 1
- 230000003676 hair loss Effects 0.000 description 1
- 201000008298 histiocytosis Diseases 0.000 description 1
- 201000006362 hypersensitivity vasculitis Diseases 0.000 description 1
- 201000006417 multiple sclerosis Diseases 0.000 description 1
- 210000000056 organs Anatomy 0.000 description 1
- 201000008482 osteoarthritis Diseases 0.000 description 1
- 201000004681 psoriasis Diseases 0.000 description 1
- 201000001263 psoriatic arthritis Diseases 0.000 description 1
- 230000002685 pulmonary Effects 0.000 description 1
- 230000000241 respiratory Effects 0.000 description 1
- 201000004193 respiratory failure Diseases 0.000 description 1
- 201000001223 septic arthritis Diseases 0.000 description 1
- 201000010874 syndrome Diseases 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
Description
本発明のペプチドはリウマチ性関節炎を治療する効能が優れている。本発明の炎症性疾患には、これに限定はされないが、浮腫、炎症性腸疾患、腹膜炎、蜂窩織炎、膵臓炎、骨髄炎、ショックを誘発するトラウマ、気管支喘息、アレルギー性鼻炎、包嚢性繊維腫、急性気管支炎、慢性気管支炎、急性細気管支炎、慢性細気管支炎、骨関節炎、痛風、脊椎炎、硬直性脊椎、ライタスシンドローム(Reiter's syndrom)、乾癬性関節炎、炎症性腸疾患を同伴した脊椎炎、青少年関節症、青少年交錯関節症、反応性関節症、感染性関節炎、感染後関節炎、リン菌関節炎、結核関節炎、ウィルス関節炎、真菌関節炎、梅毒関節炎、ライム病、脈管炎シンドロームを同伴した関節炎、多発性動脈炎、過敏性脈管炎、ウェグナー肉芽腫症、多発性筋肉痛、巨大細胞動脈炎、カルシウム結晶蓄積関節炎、胃痛風、関節性関節炎、滑液嚢炎、痩果炎、テニス・エルボー、神経性関節炎、関節血症、ヘーノホシェーンライン紫斑病、多心性膜内組織球症、異常血色素症、ヘモグロビン痛、家族性地中海熱、バセット病(Behcet's disease)、全身性紅斑性嚢瘡、多発性硬化症、肺血症、肺血症ショック、急性呼吸器痛症シンドローム、複合器官異常、慢性閉鎖性肺疾患、リウマチ性性関節炎、急性呼吸不全症候群がある。さらに、炎症性疾患は急性及び慢性湿疹、アトピー性皮膚炎、接触性皮膚炎、皮膚炎性脱毛、剥落性皮膚炎、日光性皮膚炎及び乾癬等がある。好ましくは、本発明の炎症性疾患はリウマチ性性関節炎である。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2010-0121894 | 2010-12-02 | ||
| KR20100121894 | 2010-12-02 | ||
| PCT/KR2011/009318 WO2012074330A2 (en) | 2010-12-02 | 2011-12-02 | Fusion peptide comprising dhfas-1 domain and mmp substrate and use thereof for preventing and treating rheumatoid arthritis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014502160A JP2014502160A (ja) | 2014-01-30 |
| JP2014502160A5 true JP2014502160A5 (ja) | 2016-08-04 |
| JP5982394B2 JP5982394B2 (ja) | 2016-08-31 |
Family
ID=46172429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013541927A Active JP5982394B2 (ja) | 2010-12-02 | 2011-12-02 | ＭＭＰ基質で連結したβｉｇ−ｈ３断片ペプチド及びそのリウマチ性関節炎予防及び治療用途 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9605038B2 (ja) |
| EP (1) | EP2646473B1 (ja) |
| JP (1) | JP5982394B2 (ja) |
| KR (1) | KR101369502B1 (ja) |
| CN (1) | CN103370340B (ja) |
| WO (1) | WO2012074330A2 (ja) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110770249B (zh) * | 2017-04-21 | 2024-03-29 | 英特瑞克斯顿股份有限公司 | 递送包含基质金属蛋白酶的自体细胞用于治疗硬皮病 |
| KR102111780B1 (ko) * | 2018-07-23 | 2020-05-15 | 순천향대학교 산학협력단 | 지방산 합성 효소를 포함하는 폐기종 또는 폐섬유화증의 예방 또는 치료용 약학 조성물 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0202253D0 (sv) * | 2002-07-18 | 2002-07-18 | Index Pharmaceuticals Ab | Novel sequence information and methods for its use in diagnosis and therapy XIII |
| KR100568755B1 (ko) | 2003-04-03 | 2006-04-07 | 주식회사 리젠 바이오텍 | Ｙｈ 모티프를 포함하는 펩타이드를 유효성분으로함유하는 혈관신생 억제제 |
| KR100635540B1 (ko) * | 2004-10-12 | 2006-10-18 | 경북대학교 산학협력단 | 신규한 염증성 질환의 예방 또는 치료용 약학적 조성물 |
| KR100804166B1 (ko) * | 2005-02-28 | 2008-02-19 | 경북대학교 산학협력단 | 피브로넥틴 및 βｉｇ-ｈ3의 일부 도메인으로 이루어진 재조합 단백질을 포함하는 혈관신생 억제용 조성물 |
| CN100362020C (zh) * | 2006-02-13 | 2008-01-16 | 浙江理工大学 | 一种重组动物丝－rgd融合蛋白及其生物合成方法 |
| KR20090050667A (ko) * | 2007-11-16 | 2009-05-20 | 경북대학교 산학협력단 | βｉｇ-ｈ3 단편을 유효성분으로 포함하는 류마티스관절염의 예방 및 치료용 약학적 조성물 |
-
2011
- 2011-12-02 JP JP2013541927A patent/JP5982394B2/ja active Active
- 2011-12-02 KR KR1020110128557A patent/KR101369502B1/ko active IP Right Grant
- 2011-12-02 CN CN201180057966.3A patent/CN103370340B/zh active Active
- 2011-12-02 WO PCT/KR2011/009318 patent/WO2012074330A2/en active Application Filing
- 2011-12-02 EP EP11845862.9A patent/EP2646473B1/en active Active
-
2013
- 2013-05-31 US US13/907,327 patent/US9605038B2/en active Active
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