JP2014500874A5 - - Google Patents
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- Publication number
- JP2014500874A5 JP2014500874A5 JP2013538999A JP2013538999A JP2014500874A5 JP 2014500874 A5 JP2014500874 A5 JP 2014500874A5 JP 2013538999 A JP2013538999 A JP 2013538999A JP 2013538999 A JP2013538999 A JP 2013538999A JP 2014500874 A5 JP2014500874 A5 JP 2014500874A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- antibody
- binding fragment
- seq
- igf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000427 antigen Substances 0.000 claims 23
- 102000036639 antigens Human genes 0.000 claims 23
- 108091007433 antigens Proteins 0.000 claims 23
- 239000012634 fragment Substances 0.000 claims 23
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 claims 7
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 claims 7
- 108090001117 Insulin-Like Growth Factor II Proteins 0.000 claims 6
- 102000048143 Insulin-Like Growth Factor II Human genes 0.000 claims 6
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 201000011510 cancer Diseases 0.000 claims 4
- 230000037396 body weight Effects 0.000 claims 3
- 206010009944 Colon cancer Diseases 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 239000012472 biological sample Substances 0.000 claims 2
- 238000012423 maintenance Methods 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 206010005003 Bladder cancer Diseases 0.000 claims 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 1
- 102100037852 Insulin-like growth factor I Human genes 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 208000015634 Rectal Neoplasms Diseases 0.000 claims 1
- 201000011683 Small Cell Sarcoma Diseases 0.000 claims 1
- 206010043515 Throat cancer Diseases 0.000 claims 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 1
- 208000002495 Uterine Neoplasms Diseases 0.000 claims 1
- 230000003796 beauty Effects 0.000 claims 1
- 210000000481 breast Anatomy 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 206010073071 hepatocellular carcinoma Diseases 0.000 claims 1
- 231100000844 hepatocellular carcinoma Toxicity 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 206010061289 metastatic neoplasm Diseases 0.000 claims 1
- 238000006386 neutralization reaction Methods 0.000 claims 1
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 1
- 206010038038 rectal cancer Diseases 0.000 claims 1
- 201000001275 rectum cancer Diseases 0.000 claims 1
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 1
- 201000005112 urinary bladder cancer Diseases 0.000 claims 1
- 206010046766 uterine cancer Diseases 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41431810P | 2010-11-16 | 2010-11-16 | |
| US61/414,318 | 2010-11-16 | ||
| US201161529614P | 2011-08-31 | 2011-08-31 | |
| US61/529,614 | 2011-08-31 | ||
| PCT/US2011/060839 WO2012068148A1 (en) | 2010-11-16 | 2011-11-15 | Regimens for treatments using anti-igf antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014500874A JP2014500874A (ja) | 2014-01-16 |
| JP2014500874A5 true JP2014500874A5 (cg-RX-API-DMAC7.html) | 2015-01-08 |
Family
ID=46084376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013538999A Pending JP2014500874A (ja) | 2010-11-16 | 2011-11-15 | 抗ｉｇｆ抗体を用いた治療レジメン |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20130330353A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2640421A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2014500874A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2011329067A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2818561A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012068148A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2892750A1 (en) * | 2012-11-29 | 2014-06-05 | Bayer Healthcare Llc | Monoclonal antibodies agaisnt activated protein c (apc) |
| CA2934313A1 (en) * | 2013-12-19 | 2015-06-25 | Medimmune, Llc | Compositions and methods for treating sarcoma |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2005018671A1 (ja) * | 2003-08-21 | 2006-10-19 | 協和醗酵工業株式会社 | 癌転移阻害剤 |
| JP5302007B2 (ja) * | 2005-12-13 | 2013-10-02 | アストラゼネカ アクチボラグ | インスリン様増殖因子に特異的な結合タンパク質およびその使用 |
| WO2007118214A2 (en) * | 2006-04-07 | 2007-10-18 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Antibody compositions and methods for treatment of neoplastic disease |
| NZ587504A (en) * | 2008-02-21 | 2012-09-28 | Merck Sharp & Dohme | Benzopyrazole derivatives as ERK inhibitors |
| PT2376116E (pt) * | 2008-12-12 | 2016-02-24 | Boehringer Ingelheim Int | Anticorpos anti-igf |
-
2011
- 2011-11-15 JP JP2013538999A patent/JP2014500874A/ja active Pending
- 2011-11-15 EP EP11842005.8A patent/EP2640421A4/en not_active Withdrawn
- 2011-11-15 WO PCT/US2011/060839 patent/WO2012068148A1/en not_active Ceased
- 2011-11-15 US US13/884,843 patent/US20130330353A1/en not_active Abandoned
- 2011-11-15 AU AU2011329067A patent/AU2011329067A1/en not_active Abandoned
- 2011-11-15 CA CA2818561A patent/CA2818561A1/en not_active Abandoned
-
2015
- 2015-03-13 US US14/657,134 patent/US20150183860A1/en not_active Abandoned