JP2014500735A - サイトフェレーシスカートリッジおよびその使用 - Google Patents

サイトフェレーシスカートリッジおよびその使用 Download PDF

Info

Publication number
JP2014500735A
JP2014500735A JP2013534056A JP2013534056A JP2014500735A JP 2014500735 A JP2014500735 A JP 2014500735A JP 2013534056 A JP2013534056 A JP 2013534056A JP 2013534056 A JP2013534056 A JP 2013534056A JP 2014500735 A JP2014500735 A JP 2014500735A
Authority
JP
Japan
Prior art keywords
cartridge
fluid
scd
range
housing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2013534056A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014500735A5 (enExample
Inventor
エイチ． デビット ヒュームズ
デボラ バフィントン
クリストファー ジェイ． ピノ
Original Assignee
サイトフェリックス インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by サイトフェリックス インコーポレイテッド filed Critical サイトフェリックス インコーポレイテッド
Publication of JP2014500735A publication Critical patent/JP2014500735A/ja
Publication of JP2014500735A5 publication Critical patent/JP2014500735A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3672—Means preventing coagulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3672—Means preventing coagulation
    • A61M1/3675—Deactivation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1698—Blood oxygenators with or without heat-exchangers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0427—Platelets; Thrombocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0439—White blood cells; Leucocytes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/44—Cartridge types

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
JP2013534056A 2010-10-15 2011-10-14 サイトフェレーシスカートリッジおよびその使用 Pending JP2014500735A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39380510P 2010-10-15 2010-10-15
US61/393,805 2010-10-15
PCT/US2011/056469 WO2012051595A1 (en) 2010-10-15 2011-10-14 Cytopheresic cartridge and use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017213380A Division JP7057098B2 (ja) 2010-10-15 2017-11-06 サイトフェレーシスカートリッジおよびその使用

Publications (2)

Publication Number Publication Date
JP2014500735A true JP2014500735A (ja) 2014-01-16
JP2014500735A5 JP2014500735A5 (enExample) 2014-11-27

Family

ID=44908112

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2013534056A Pending JP2014500735A (ja) 2010-10-15 2011-10-14 サイトフェレーシスカートリッジおよびその使用
JP2017213380A Active JP7057098B2 (ja) 2010-10-15 2017-11-06 サイトフェレーシスカートリッジおよびその使用
JP2020200927A Active JP7224329B2 (ja) 2010-10-15 2020-12-03 サイトフェレーシスカートリッジおよびその使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2017213380A Active JP7057098B2 (ja) 2010-10-15 2017-11-06 サイトフェレーシスカートリッジおよびその使用
JP2020200927A Active JP7224329B2 (ja) 2010-10-15 2020-12-03 サイトフェレーシスカートリッジおよびその使用

Country Status (9)

Country Link
US (4) US20130288370A1 (enExample)
EP (1) EP2627369B1 (enExample)
JP (3) JP2014500735A (enExample)
CN (1) CN103260670A (enExample)
AU (1) AU2011315839B2 (enExample)
CA (1) CA2814586C (enExample)
ES (1) ES2909788T3 (enExample)
IL (1) IL225713A0 (enExample)
WO (1) WO2012051595A1 (enExample)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014061285A (ja) * 2012-08-31 2014-04-10 Asahi Kasei Medical Co Ltd 臓器炎症抑制用基材及びデバイス
JPWO2015125852A1 (ja) * 2014-02-19 2017-03-30 東レ株式会社 血小板浮遊液洗浄用の中空糸膜モジュール
JP2017513636A (ja) * 2014-04-24 2017-06-01 エクスセラ メディカル コーポレイション 高流量を用いて血液から細菌を除去するための方法
US10639413B2 (en) 2013-06-24 2020-05-05 Exthera Medical Corporation Blood filtration system containing mannose coated substrate
US10688239B2 (en) 2005-12-13 2020-06-23 Exthera Medical Corporation Method for extracorporeal removal of a pathogenic microbe, an inflammatory cell or an inflammatory protein from blood
US10857283B2 (en) 2014-09-22 2020-12-08 Exthera Medical Corporation Wearable hemoperfusion device
US11123466B2 (en) 2009-12-01 2021-09-21 Exthera Medical Corporation Methods for removing cytokines from blood with surface immobilized polysaccharides
US11266772B2 (en) 2012-06-13 2022-03-08 Exthera Medical Corporation Use of heparin and carbohydrates to treat cancer
US11306346B2 (en) 2013-11-08 2022-04-19 Exthera Medical Corporation Methods for diagnosing infectious diseases using adsorption media
US11911551B2 (en) 2016-03-02 2024-02-27 Exthera Medical Corporation Method for treating drug intoxication
US12090261B2 (en) 2019-05-16 2024-09-17 Exthera Medical Corporation Method for modulating endothelial glycocalyx structure

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2627369B1 (en) * 2010-10-15 2022-01-12 SeaStar Medical, Inc. Cytopheresic cartridge and use thereof
EP4194024A1 (en) * 2012-01-09 2023-06-14 SeaStar Medical, Inc. Cartridge and method for increasing myocardial function
EP2886140A1 (en) * 2013-12-17 2015-06-24 University of Limerick An apparatus for the extracorporeal treatment of blood
EP3177904A4 (en) * 2014-08-07 2018-01-03 The General Hospital Corporation Platelet-targeted microfluidic isolation of cells
KR102463285B1 (ko) * 2014-12-25 2022-11-07 테루모 가부시키가이샤 체외 순환 관리 장치, 및 이를 갖는 체외 순환 장치
CN105214157B (zh) * 2015-11-02 2017-06-30 珠海健帆生物科技股份有限公司 血液净化装置及系统
CN106267410B (zh) * 2016-07-01 2019-03-08 翁炳焕 艾滋病感染细胞分离器
CN106110286A (zh) * 2016-08-23 2016-11-16 万龙 一种适用于老年患者的治疗巨细胞动脉炎的中药制剂
CN109803748A (zh) * 2016-09-30 2019-05-24 东丽株式会社 培养血小板浓缩组件及使用其的血小板制剂的制造方法
JP2021522519A (ja) * 2018-04-19 2021-08-30 スティッキーセル ピーティーワイ リミテッドＳｔｉｃｋｙｃｅｌｌ Ｐｔｙ Ｌｔｄ 感染症の技術分野における白血球補充
CN111840780B (zh) * 2020-06-24 2022-07-12 安徽通灵仿生科技有限公司 适用于ecmo期间血液净化装置的管路适配器
CN115137899A (zh) * 2022-06-24 2022-10-04 深圳华源再生医学有限公司 多功能人工脏器装置
CN116617482B (zh) * 2023-04-28 2024-12-17 天津大学温州安全(应急)研究院 一种用于动物的ecmo联合血液净化装置
WO2025101550A1 (en) 2023-11-07 2025-05-15 Fresenius Medical Care Holdings, Inc. Small diameter hollow fiber membrane and methods for making the same
WO2025101552A1 (en) 2023-11-07 2025-05-15 Fresenius Medical Care Holdings, Inc. Dialyzers utilizing small diameter hollow fiber membranes

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008007465A1 (fr) * 2006-07-12 2008-01-17 Asahi Kasei Medical Co., Ltd. Procédé d'élimination d'un prion anormal dans une préparation à base de sang
WO2008038785A1 (en) * 2006-09-29 2008-04-03 Toray Industries, Inc. Cell-adsorbing column
WO2009029801A2 (en) * 2007-08-31 2009-03-05 The Regents Of The University Of Michigan Selective cytopheresis devices and related methods thereof
JP2009529924A (ja) * 2005-09-09 2009-08-27 メムブラーナ ゲゼルシャフト ミット ベシュレンクテル ハフツング 血液から白血球を除去するための方法
WO2009128564A1 (ja) * 2008-04-18 2009-10-22 日機装株式会社 血球除去用吸着体

Family Cites Families (128)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE637951A (enExample) 1962-09-29
US3489145A (en) 1966-08-08 1970-01-13 Surgeon General Of The Public Method and apparatus for continuous separation of blood in vivo
GB2018151B (en) 1978-03-06 1982-12-08 Asahi Chemical Ind Seperation of leukocytes from leukocyte-containing suspension by filtration
DE2911508A1 (de) 1978-03-28 1979-10-04 Kuraray Co Fluidbehandlungsvorrichtung
US4334993A (en) 1979-12-05 1982-06-15 Baxter Travenol Laboratories, Inc. Potted-typed seal with stress relief and method of making same
US4500309A (en) 1982-05-07 1985-02-19 The Kansas University Endowment Association Method for regional anticoagulation during extracorporeal dialysis
US4980068A (en) 1983-08-15 1990-12-25 Lavender Ardis R System, apparatus and method for continuously fractionating blood in situ
SE441236B (sv) 1984-06-18 1985-09-23 Gambro Dialysatoren Forfarande for framstellning av en anordning innefattande en halfiberbunt
ATE84419T1 (de) 1985-09-24 1993-01-15 Item Dev Ab Kontinuierliche intravenoese infusion von adenosin an menschlichen patienten, einheitsdosierungsform von adenosin und dessen verwendung bei der herstellung von arzneimitteln.
SE8601891D0 (sv) 1986-04-24 1986-04-24 Svante Jonsson Maskin for plasmabytesbehandling och trombocytgivning
SE454847B (sv) 1987-08-31 1988-06-06 Gambro Dialysatoren Anordning for diffusion och/eller filtrering samt forfarande for tillverkning av denna anordning
WO1989001967A1 (en) 1987-09-03 1989-03-09 Brown University Research Foundation Blood purification with cultured renal cells
CA1325770C (en) 1988-04-04 1994-01-04 Toru Kuroda Adsorber module for whole blood treatment and an adsorber apparatus containing the adsorber module
US5104373A (en) 1988-09-22 1992-04-14 American Immuno Tech, Inc. Method and apparatus for extracorporeal blood treatment
US5229012A (en) 1989-05-09 1993-07-20 Pall Corporation Method for depletion of the leucocyte content of blood and blood components
US5344561A (en) 1989-05-09 1994-09-06 Pall Corporation Device for depletion of the leucocyte content of blood and blood components
US5100564A (en) 1990-11-06 1992-03-31 Pall Corporation Blood collection and processing system
US5032615A (en) 1989-10-31 1991-07-16 The Regents Of The University Of California Continuous hemodialysis using citrate
US5266219A (en) 1989-12-28 1993-11-30 Pall Corporation Device and method for separating plasma from blood
ATE170982T1 (de) 1990-02-14 1998-09-15 Pentapharm Ag Inhibitoren zur antikoagulierenden vorbehandung von blutproben
US5383847A (en) 1990-03-29 1995-01-24 Therakos, Inc. Non-specific immune system enhancement
EP0461791B1 (en) 1990-06-11 1997-01-02 Hector D. Barone Aortic graft and apparatus for repairing an abdominal aortic aneurysm
US5362406A (en) 1990-07-27 1994-11-08 Pall Corporation Leucocyte depleting filter device and method of use
US5217627A (en) 1990-11-06 1993-06-08 Pall Corporation System and method for processing biological fluid
US5486286A (en) 1991-04-19 1996-01-23 Althin Medical, Inc. Apparatus for performing a self-test of kidney dialysis membrane
SE502103C2 (sv) 1991-08-01 1995-08-14 Gambro Dialysatoren Filterenhet för överföring av massa och/eller värme innehållande hålrumsfibrer
US5443743A (en) 1991-09-11 1995-08-22 Pall Corporation Gas plasma treated porous medium and method of separation using same
CA2074671A1 (en) 1991-11-04 1993-05-05 Thomas Bormann Device and method for separating plasma from a biological fluid
CA2121603A1 (en) 1991-11-15 1993-05-16 Hirohisa Okuyama Antiphlogistic-analgesic plaster
US5804079A (en) 1991-12-23 1998-09-08 Baxter International Inc. Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes
US5403272A (en) 1992-05-29 1995-04-04 Baxter International Inc. Apparatus and methods for generating leukocyte free platelet concentrate
IL104670A (en) 1993-02-09 1998-04-05 Travenol Lab Israel Ltd Leukocyte removal method and filter unit for same
ATE204478T1 (de) 1993-05-03 2001-09-15 Genentech Inc Inhibierung von leukozytenadhäsion
US5567443A (en) 1993-08-04 1996-10-22 Japan Immunoresearch Laboratories Co., Ltd. Method of treating inflammatory diseases
US5571418A (en) 1993-08-20 1996-11-05 Lee; Patrice A. Hemofiltration of toxic mediator-related disease
US5545339A (en) 1994-02-25 1996-08-13 Pall Corporation Method for processing biological fluid and treating separated component
EP0692268B2 (de) 1994-07-13 2005-02-09 Fresenius Medical Care Deutschland GmbH Substituataufbereitung bei der Hämofiltration oder Hämodiafiltration
US5582907A (en) 1994-07-28 1996-12-10 Pall Corporation Melt-blown fibrous web
JPH10508343A (ja) 1994-07-28 1998-08-18 ポール・コーポレーション 繊維質ウェブ及びその製造方法
US5565149A (en) 1995-03-15 1996-10-15 Permea, Inc. Control of dissolved gases in liquids
US5836934A (en) 1995-06-07 1998-11-17 Baxter International Inc. Closed system and methods for mixing additive solutions while removing undesired matter from blood cells
KR100254745B1 (ko) 1995-07-10 2000-05-01 마모루 우메가에 염증성 질환치료용 체외 순환 혈액 처리 시스템
US5591972A (en) 1995-08-03 1997-01-07 Illumination Technologies, Inc. Apparatus for reading optical information
DE19528907C1 (de) 1995-08-05 1996-11-07 Fresenius Ag Vorrichtung zur Ermittlung hämodynamischer Parameter während einer extrakorporalen Blutbehandlung
DE19541783C1 (de) 1995-11-09 1997-03-27 Fresenius Ag Verfahren zum Betreiben einer Blutbehandlungsvorrichtung zur Ermittlung hämodynamischer Parameter während einer extrakorporalen Blutbehandlung und Vorrichtung zur Ermittlung hämodynamischer Parameter während einer extrakorporalen Blutbehandlung
JPH1017493A (ja) 1996-07-02 1998-01-20 Masashi Fujii カルシウムの金属イオン封鎖剤を含む抗炎症性または抗アレルギー性皮膚外用剤
WO1998001208A1 (en) 1996-07-08 1998-01-15 Memtec America Corporation Cationically charge-modified membranes
US6231770B1 (en) 1996-07-09 2001-05-15 Pall Corporation Multiple element filter and method of using therefor
US6150164A (en) 1996-09-30 2000-11-21 The Regents Of The University Of Michigan Methods and compositions of a bioartificial kidney suitable for use in vivo or ex vivo
US6045899A (en) 1996-12-12 2000-04-04 Usf Filtration & Separations Group, Inc. Highly assymetric, hydrophilic, microfiltration membranes having large pore diameters
US6830553B1 (en) 1997-02-14 2004-12-14 Nxstage Medical, Inc. Blood treatment systems and methods that maintain sterile extracorporeal processing conditions
US6595943B1 (en) 1997-02-14 2003-07-22 Nxstage Medical, Inc. Systems and methods for controlling blood flow and waste fluid removal during hemofiltration
AU6120298A (en) 1997-03-07 1998-09-22 Takeda Chemical Industries Ltd. 2-peperazinone-1-acetic acid derivatives and their use
DE19712298C2 (de) 1997-03-24 1999-05-20 Fresenius Ag Vorrichtung und Verfahren zum Trennen von Blut in Blutkomponenten
US6889082B2 (en) 1997-10-09 2005-05-03 Orqis Medical Corporation Implantable heart assist system and method of applying same
US6123859A (en) 1998-04-22 2000-09-26 Hemasure Inc. Method for in-line filtering biological liquid
US6287516B1 (en) 1998-07-10 2001-09-11 Immunocept, L.L.C. Hemofiltration systems, methods, and devices used to treat inflammatory mediator related disease
JP3640824B2 (ja) 1999-01-07 2005-04-20 テルモ株式会社 白血球除去フィルターおよびその製造方法
AU2692900A (en) 1999-03-17 2000-10-04 Japan Immuno Research Laboratories Co., Ltd. Treatment of disease
EP1171178B1 (en) 1999-04-23 2006-11-22 RenaMed Biologics, Inc. Extracorporeal circuit
JP2001149471A (ja) 1999-11-29 2001-06-05 Nikkiso Co Ltd 中空糸型血液浄化器及びその包装方法
US6736972B1 (en) 2000-03-24 2004-05-18 Immunocept, L.L.C. Method and system for providing therapeutic agents with hemofiltration for reducing inflammatory mediator related diseases
JP2001276217A (ja) 2000-04-04 2001-10-09 Dountsuendorufaa Udo 単一又は複数の疾患のある患者での組織、血漿又は血液透析用のバイオコートされた吸着剤
US6566402B2 (en) 2000-05-24 2003-05-20 Uab Research Foundation Use of citrate-containing dialysate for renal dialysis treatment
ES2288899T3 (es) 2000-10-04 2008-02-01 Astellas Pharma Inc. Uso de un antagonista de vasopresina tal como conivaptan en la fabricacion de un medicamento para el tratamiento de la hipertension pulmonar.
US20020107469A1 (en) 2000-11-03 2002-08-08 Charles Bolan Apheresis methods and devices
DE10114283C2 (de) 2000-12-22 2003-04-24 Fresenius Medical Care De Gmbh Verfahren zur Ermittlung der Ionenkonzentration des Blutes eines Patienten bei der citrat-antikoagulierten Hämodialyse und/oder Hämofiltration; Dialysegerät
US6706274B2 (en) 2001-01-18 2004-03-16 Scimed Life Systems, Inc. Differential delivery of nitric oxide
US6706008B2 (en) 2001-03-06 2004-03-16 Baxter International Inc. Automated system and method for withdrawing compounds from blood
US6582386B2 (en) 2001-03-06 2003-06-24 Baxter International Inc. Multi-purpose, automated blood and fluid processing systems and methods
US6653131B2 (en) 2001-08-30 2003-11-25 The Regents Of The University Of Michigan Method of treating systemic inflammatory response syndrome
US7166443B2 (en) 2001-10-11 2007-01-23 Aviva Biosciences Corporation Methods, compositions, and automated systems for separating rare cells from fluid samples
US8986944B2 (en) 2001-10-11 2015-03-24 Aviva Biosciences Corporation Methods and compositions for separating rare cells from fluid samples
US7442546B2 (en) 2002-03-15 2008-10-28 The Regents Of The University Of Michigan Method of modulating inflammatory response
US7531133B2 (en) 2002-09-10 2009-05-12 Pulmonox Technologies Corporation Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma
WO2004024300A1 (en) 2002-09-11 2004-03-25 The Regents Of The University Of Michigan Ultrafiltration membrane, device, bioartificial organ and methods
US7459169B2 (en) 2002-10-21 2008-12-02 Allvivo, Inc. Surface coating comprising bioactive compound
WO2004050146A1 (ja) 2002-12-02 2004-06-17 Asahi Medical Co., Ltd. 白血球除去方法、白血球除去フィルター及びその使用
US7351218B2 (en) 2002-12-20 2008-04-01 Gambro Lundia Ab Device and process for extracorporeal treatment by citrate anticoagulant
WO2004064730A2 (en) 2003-01-14 2004-08-05 Cytokinetics, Inc. Compounds, compositions and methods
JP2004243048A (ja) 2003-02-10 2004-09-02 Besutekku:Kk 電位治療装置制御方法、電位治療装置及び白血球分画の顆粒球とリンパ球との比率を調整する方法
US7201730B2 (en) 2003-03-17 2007-04-10 Hemavation, Llc Device and method for reducing inflammatory mediators in blood
US7297270B2 (en) 2003-04-04 2007-11-20 Chf Solutions, Inc. Hollow fiber filter for extracorporeal blood circuit
AU2004248962A1 (en) 2003-06-21 2004-12-29 Lifeforce Group Plc Leukocyte cell banks
US7875272B2 (en) 2003-06-27 2011-01-25 Ethicon, Incorporated Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells
DE60307849T2 (de) 2003-09-23 2007-01-04 Fresenius Hemocare Italia S.R.L., Cavezzo Filter, Reinigungsvorrichtung und Verfahren zum Entfernen von Substanzen aus Blutprodukten
US7029456B2 (en) 2003-10-15 2006-04-18 Baxter International Inc. Medical fluid therapy flow balancing and synchronization system
EP1718603A4 (en) 2004-02-09 2009-09-23 Noxilizer Inc MOLECULES RELEASING NITROGEN MONOXIDE
US20050215937A1 (en) 2004-03-05 2005-09-29 Spinale Francis G System and method for filtering leukocytes in cardiac surgery
AU2005240082B2 (en) 2004-04-30 2009-07-23 Innatus Corporation Method and system to remove soluble TNFR1,TNFR2, and IL2 in patients
JP4854083B2 (ja) 2004-06-09 2012-01-11 旭化成メディカル株式会社 白血球除去方法およびその方法に用いられるフィルター
EP1765433B1 (en) 2004-06-21 2016-05-18 Hemolife Medical, Inc. Plasma detoxification and volume control system
CA2572179A1 (en) 2004-06-23 2006-01-19 Myogen, Inc. Enoximone formulations and their use in the treatment of pde-iii mediated diseases
US8708945B2 (en) 2004-07-22 2014-04-29 Asahi Kasei Medical Co., Ltd. Method for suppressing surgical site infection and column to be used for the method
WO2006083322A2 (en) 2004-07-29 2006-08-10 Ligocyte Pharmaceuticals, Inc. Methods for the treatment and prevention of infection using anti-selectin agents
CN101098704B (zh) 2005-01-06 2011-07-13 旭化成医疗株式会社 白血球除去方法
CN101151056B (zh) 2005-03-31 2012-07-04 东丽株式会社 吸附材料和体外循环柱
EP1931445B1 (en) 2005-08-31 2018-08-01 Gambro Lundia AB Cyclic olefin copolymer as a leukoreduction material
US7874998B2 (en) 2005-11-04 2011-01-25 The Regents Of The University Of Michigan Filtration devices and related methods thereof
WO2007079410A2 (en) 2005-12-30 2007-07-12 C.R Bard Inc. Embolus blood clot filter delivery system
JP2009525781A (ja) 2006-02-02 2009-07-16 イノベーティブ バイオ セラピーズ 細胞をベースとする体外治療装置および送達システム
US20090081296A1 (en) 2006-02-02 2009-03-26 Humes H David Extracorporeal cell-based therapeutic device and delivery system
US7527737B2 (en) 2006-05-09 2009-05-05 Wang Xiangyu Hemodialysis apparatus and methods
EP2041299A4 (en) 2006-07-14 2010-01-13 Aviva Biosciences Corp METHOD AND COMPOSITIONS FOR DETECTION OF RARE CELLS FROM A BIOLOGICAL SAMPLE
JP5268250B2 (ja) 2006-12-05 2013-08-21 旭化成メディカル株式会社 炎症性サイトカイン産生を抑制するフィルター材、装置、および方法
JP5424894B2 (ja) * 2007-01-13 2014-02-26 メムブラーナ ゲゼルシャフト ミット ベシュレンクテル ハフツング 血液から白血球を除去するための装置
JP2008206753A (ja) 2007-02-27 2008-09-11 Toray Ind Inc 炎症性疾患処置カラム
US20080319369A1 (en) 2007-06-22 2008-12-25 George Trutza Systems and Methods for Removing Fluid and Atherogenic, Thrombotic, and Inflammatory Markers From Blood
WO2009039378A2 (en) 2007-09-19 2009-03-26 The Charles Stark Draper Laboratory, Inc. Microfluidic structures for biomedical applications
US20110197628A1 (en) 2008-01-25 2011-08-18 Baylor College Of Medicine Cryoaggregate filtration for the treatment of cardiomyopathy and other autoimmune diseases
CN102171332A (zh) 2008-06-18 2011-08-31 创新生物制剂疗法公司 促进肾前体细胞增殖的方法
CA2734200A1 (en) 2008-08-15 2010-02-18 Innovative Biotherapies, Inc. An extracorporeal cell-based therapeutic device and delivery system
DE102008045127A1 (de) 2008-09-01 2010-03-04 Heinrich, Hans-Werner, Prof. Dr. Filtersystem zur extrakorporalen Abreicherung von aktivierten Polymorphkernigen Granuloyzten (Polymorphonuclear leukocytes-PMNs)
CN102186880A (zh) 2008-09-10 2011-09-14 Ith免疫治疗控股股份公司 炎症的治疗
US9492468B2 (en) 2008-10-03 2016-11-15 Pericor Therapeutics, Inc. Methods and compositions for treatment of acute heart failure
CA2760305A1 (en) 2009-04-28 2010-11-04 Boehringer Ingelheim International Gmbh Ex-vivo treatment of immunological disorders with pkc-theta inhibitors
CA2776613A1 (en) 2009-10-07 2011-04-14 University Of Pittsburgh - Of The Commonwealth System Of Higher Educatio N Devices, systems and methods for cell modification
WO2011044369A1 (en) 2009-10-08 2011-04-14 Otsuka Pharmaceutical Co., Ltd. An immunoactivation blood perfusion filter for the treatment of malignant tumors
US20110250578A1 (en) 2010-04-13 2011-10-13 Northern Alberta Institute Of Technology Ventilator test lung and trigger assembly
EP2627369B1 (en) * 2010-10-15 2022-01-12 SeaStar Medical, Inc. Cytopheresic cartridge and use thereof
US9199026B2 (en) 2011-01-07 2015-12-01 Somerset Group Enterprises, Inc. Modular extracorporeal systems and methods for treating blood-borne diseases
CN103561633B (zh) 2011-03-24 2016-02-24 意昂外科手术有限公司 腹腔镜系统
US20150246169A1 (en) 2011-10-14 2015-09-03 Cytopherx, Inc. Cartridge and method for increasing myocardial function
EP4194024A1 (en) 2012-01-09 2023-06-14 SeaStar Medical, Inc. Cartridge and method for increasing myocardial function
WO2014073105A1 (ja) 2012-11-12 2014-05-15 三浦工業株式会社 バラスト水処理装置
CN105592905B (zh) 2013-11-07 2018-06-29 三浦工业株式会社 压载水处理装置
WO2015095553A1 (en) 2013-12-20 2015-06-25 Nephrogenesis, Llc Methods and apparatus for kidney dialysis
US20170000937A1 (en) 2014-01-21 2017-01-05 Nephro-Solutions Ag Dialysis Apparatus Comprising a Dialyzer

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009529924A (ja) * 2005-09-09 2009-08-27 メムブラーナ ゲゼルシャフト ミット ベシュレンクテル ハフツング 血液から白血球を除去するための方法
WO2008007465A1 (fr) * 2006-07-12 2008-01-17 Asahi Kasei Medical Co., Ltd. Procédé d'élimination d'un prion anormal dans une préparation à base de sang
WO2008038785A1 (en) * 2006-09-29 2008-04-03 Toray Industries, Inc. Cell-adsorbing column
WO2009029801A2 (en) * 2007-08-31 2009-03-05 The Regents Of The University Of Michigan Selective cytopheresis devices and related methods thereof
WO2009128564A1 (ja) * 2008-04-18 2009-10-22 日機装株式会社 血球除去用吸着体

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11065378B2 (en) 2005-12-13 2021-07-20 Exthera Medical Corporation Method for extracorporeal removal of a pathogenic microbe, an inflammatory cell or an inflammatory protein from blood
US10688239B2 (en) 2005-12-13 2020-06-23 Exthera Medical Corporation Method for extracorporeal removal of a pathogenic microbe, an inflammatory cell or an inflammatory protein from blood
US11123466B2 (en) 2009-12-01 2021-09-21 Exthera Medical Corporation Methods for removing cytokines from blood with surface immobilized polysaccharides
US11266772B2 (en) 2012-06-13 2022-03-08 Exthera Medical Corporation Use of heparin and carbohydrates to treat cancer
JP2014061285A (ja) * 2012-08-31 2014-04-10 Asahi Kasei Medical Co Ltd 臓器炎症抑制用基材及びデバイス
US10639413B2 (en) 2013-06-24 2020-05-05 Exthera Medical Corporation Blood filtration system containing mannose coated substrate
US11306346B2 (en) 2013-11-08 2022-04-19 Exthera Medical Corporation Methods for diagnosing infectious diseases using adsorption media
JPWO2015125852A1 (ja) * 2014-02-19 2017-03-30 東レ株式会社 血小板浮遊液洗浄用の中空糸膜モジュール
JP2021045573A (ja) * 2014-04-24 2021-03-25 エクスセラ メディカル コーポレイション 高流量を用いて血液から細菌を除去するための方法
JP2017513636A (ja) * 2014-04-24 2017-06-01 エクスセラ メディカル コーポレイション 高流量を用いて血液から細菌を除去するための方法
JP7184864B2 (ja) 2014-04-24 2022-12-06 エクスセラ メディカル コーポレイション 高流量を用いて血液から細菌を除去するための方法
US11844895B2 (en) 2014-04-24 2023-12-19 Exthera Medical Corporation Method for removing bacteria from blood using high flow rate
US10857283B2 (en) 2014-09-22 2020-12-08 Exthera Medical Corporation Wearable hemoperfusion device
US11911551B2 (en) 2016-03-02 2024-02-27 Exthera Medical Corporation Method for treating drug intoxication
US12090261B2 (en) 2019-05-16 2024-09-17 Exthera Medical Corporation Method for modulating endothelial glycocalyx structure

Also Published As

Publication number Publication date
AU2011315839A1 (en) 2013-05-02
WO2012051595A1 (en) 2012-04-19
CA2814586A1 (en) 2012-04-19
CA2814586C (en) 2024-01-30
EP2627369B1 (en) 2022-01-12
ES2909788T3 (es) 2022-05-10
US11866730B2 (en) 2024-01-09
JP7224329B2 (ja) 2023-02-17
US20250041804A1 (en) 2025-02-06
US20220177838A1 (en) 2022-06-09
CN103260670A (zh) 2013-08-21
US20130288370A1 (en) 2013-10-31
US11118162B2 (en) 2021-09-14
EP2627369A1 (en) 2013-08-21
IL225713A0 (en) 2013-06-27
AU2011315839B2 (en) 2016-02-18
US20180171293A1 (en) 2018-06-21
JP7057098B2 (ja) 2022-04-19
JP2021035635A (ja) 2021-03-04
JP2018038845A (ja) 2018-03-15
US12478923B2 (en) 2025-11-25

Similar Documents

Publication Publication Date Title
JP7224329B2 (ja) サイトフェレーシスカートリッジおよびその使用
JP5769418B2 (ja) 選択的細胞吸着除去装置およびその関連方法
JP7025866B2 (ja) 心筋機能を向上させるためのカートリッジおよび方法

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20141010

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20141010

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20150508

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20151005

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20151221

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160405

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20160720

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20161013

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170120

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20170705