JP2014500230A - 治療薬としてオリゴヌクレオチド類縁体の設計 - Google Patents

治療薬としてオリゴヌクレオチド類縁体の設計 Download PDF

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JP2014500230A
JP2014500230A JP2013527134A JP2013527134A JP2014500230A JP 2014500230 A JP2014500230 A JP 2014500230A JP 2013527134 A JP2013527134 A JP 2013527134A JP 2013527134 A JP2013527134 A JP 2013527134A JP 2014500230 A JP2014500230 A JP 2014500230A
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JP2014500230A5 (enExample
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ピー． アイヤル ラーダークリシュナン
エドワード コグリン ジョン
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スプリング バンク ファーマシューティカルズ，インコーポレイテッド
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JP2013527134A 2010-08-30 2011-08-25 治療薬としてオリゴヌクレオチド類縁体の設計 Pending JP2014500230A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40238010P 2010-08-30 2010-08-30
US61/402,380 2010-08-30
PCT/US2011/049213 WO2012030626A2 (en) 2010-08-30 2011-08-25 Design of oligonucleotide analogs as therapeutic agents

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2016028052A Division JP6210392B2 (ja) 2010-08-30 2016-02-17 治療薬としてオリゴヌクレオチド類縁体の設計
JP2017157747A Division JP2018010001A (ja) 2010-08-30 2017-08-18 治療薬としてオリゴヌクレオチド類縁体の設計

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JP2014500230A true JP2014500230A (ja) 2014-01-09
JP2014500230A5 JP2014500230A5 (enExample) 2014-10-09

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JP2013527134A Pending JP2014500230A (ja) 2010-08-30 2011-08-25 治療薬としてオリゴヌクレオチド類縁体の設計
JP2016028052A Expired - Fee Related JP6210392B2 (ja) 2010-08-30 2016-02-17 治療薬としてオリゴヌクレオチド類縁体の設計
JP2017157747A Pending JP2018010001A (ja) 2010-08-30 2017-08-18 治療薬としてオリゴヌクレオチド類縁体の設計

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JP2016028052A Expired - Fee Related JP6210392B2 (ja) 2010-08-30 2016-02-17 治療薬としてオリゴヌクレオチド類縁体の設計
JP2017157747A Pending JP2018010001A (ja) 2010-08-30 2017-08-18 治療薬としてオリゴヌクレオチド類縁体の設計

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US (2) US9040234B2 (enExample)
EP (2) EP2611451A4 (enExample)
JP (3) JP2014500230A (enExample)
KR (1) KR101926419B1 (enExample)
CN (2) CN103298475A (enExample)
WO (1) WO2012030626A2 (enExample)

Cited By (1)

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JP2016513113A (ja) * 2013-02-18 2016-05-12 スプリング バンク ファーマシューティカルズ，インコーポレイテッド ワクチンアジュバントおよび治療剤としての短鎖オリゴヌクレオチドの設計

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US9040234B2 (en) * 2010-08-30 2015-05-26 Spring Bank Pharmaceuticals, Inc. Oligonucleotide analogs as therapeutic agents
WO2013142157A1 (en) * 2012-03-22 2013-09-26 Alios Biopharma, Inc. Pharmaceutical combinations comprising a thionucleotide analog
EP3261008B1 (en) * 2015-02-17 2021-09-08 Cipherome, Inc. Method for selecting anticancer agent based on protein damage information of individual to prevent anticancer agent side effects
CA2982125A1 (en) * 2015-04-07 2016-10-13 Spring Bank Pharmaceuticals, Inc. Compositions and methods for the treatment of hbv infection
JP2018519333A (ja) * 2015-07-02 2018-07-19 スプリング バンク ファーマシューティカルズ，インコーポレイテッド ウイルス感染の治療のための組成物および方法
TW201717968A (zh) * 2015-07-14 2017-06-01 春季銀行製藥公司 誘導ｒｉｇ－ｉ和其他模式辨識受體之化合物及組成物
US11098077B2 (en) * 2016-07-05 2021-08-24 Chinook Therapeutics, Inc. Locked nucleic acid cyclic dinucleotide compounds and uses thereof
WO2018013887A1 (en) * 2016-07-15 2018-01-18 Sperovie Biosciences, Inc. Compounds, compositions, and methods for the treatment of disease
SG11201900154VA (en) * 2016-07-15 2019-02-27 Sperovie Biosciences Inc Compounds, compositions, and methods for the treatment of disease
CN110023321A (zh) 2016-08-17 2019-07-16 索尔斯蒂斯生物有限公司 多核苷酸构建体
WO2019006455A1 (en) 2017-06-30 2019-01-03 Solstice Biologics, Ltd. AUXILIARIES OF CHIRAL PHOSPHORAMIDITIS AND METHODS OF USE THEREOF
CN111484541B (zh) * 2019-01-25 2023-06-02 博瑞生物医药（苏州）股份有限公司 双核苷酸前体药物及其制备方法
EP4153752A4 (en) * 2020-05-22 2025-10-01 Harvard College INTERFERON-INDUCING OLIGONUCLEOTIDE DUPLEXES AND METHODS OF USE

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JP2005525991A (ja) * 2001-05-16 2005-09-02 マイジェニックス インコーポレイテッド 核酸ベースの化合物およびその使用方法
JP2007530449A (ja) * 2003-12-08 2007-11-01 イデラ ファーマシューティカルズ インコーポレイテッド 小オリゴヌクレオチドに基づく化合物による免疫刺激特性の調節
JP2009519345A (ja) * 2005-12-13 2009-05-14 スプリング バンク ヌクレオチドプロドラッグおよびオリゴヌクレオチドプロドラッグ
WO2009146123A2 (en) * 2008-04-03 2009-12-03 Spring Bank Compositions and methods for treating viral infections
JP2010500011A (ja) * 2006-08-08 2010-01-07 ガンサー ハートマン ５’リン酸オリゴヌクレオチドの構造および使用

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US20100040576A1 (en) * 2007-12-18 2010-02-18 The Texas A&M University System Modified Oligonucleotides For The Treatment Of Hepatitis C Infection
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JP2005525991A (ja) * 2001-05-16 2005-09-02 マイジェニックス インコーポレイテッド 核酸ベースの化合物およびその使用方法
JP2007530449A (ja) * 2003-12-08 2007-11-01 イデラ ファーマシューティカルズ インコーポレイテッド 小オリゴヌクレオチドに基づく化合物による免疫刺激特性の調節
JP2009519345A (ja) * 2005-12-13 2009-05-14 スプリング バンク ヌクレオチドプロドラッグおよびオリゴヌクレオチドプロドラッグ
JP2010500011A (ja) * 2006-08-08 2010-01-07 ガンサー ハートマン ５’リン酸オリゴヌクレオチドの構造および使用
WO2009146123A2 (en) * 2008-04-03 2009-12-03 Spring Bank Compositions and methods for treating viral infections

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BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. Vol.20(5), JPN6015033235, 11 January 2010 (2010-01-11), pages 1783 - 1786, ISSN: 0003137219 *

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016513113A (ja) * 2013-02-18 2016-05-12 スプリング バンク ファーマシューティカルズ，インコーポレイテッド ワクチンアジュバントおよび治療剤としての短鎖オリゴヌクレオチドの設計

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WO2012030626A3 (en) 2012-05-31
US20120053226A1 (en) 2012-03-01
CN107973833A (zh) 2018-05-01
JP2018010001A (ja) 2018-01-18
KR101926419B1 (ko) 2018-12-10
EP2611451A4 (en) 2014-01-15
KR20140048068A (ko) 2014-04-23
US9040234B2 (en) 2015-05-26
JP6210392B2 (ja) 2017-10-11
EP3524252A1 (en) 2019-08-14
JP2016164148A (ja) 2016-09-08
EP2611451A2 (en) 2013-07-10
WO2012030626A2 (en) 2012-03-08
CN103298475A (zh) 2013-09-11
US20150329864A1 (en) 2015-11-19

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